EP3582801A4 - ADDITIVE COMPOUNDS FOR PROTEIN PROCESSING - Google Patents
ADDITIVE COMPOUNDS FOR PROTEIN PROCESSING Download PDFInfo
- Publication number
- EP3582801A4 EP3582801A4 EP18754459.8A EP18754459A EP3582801A4 EP 3582801 A4 EP3582801 A4 EP 3582801A4 EP 18754459 A EP18754459 A EP 18754459A EP 3582801 A4 EP3582801 A4 EP 3582801A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- protein processing
- additive compounds
- additive
- compounds
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000654 additive Substances 0.000 title 1
- 230000000996 additive effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 230000020978 protein processing Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Mycology (AREA)
- Veterinary Medicine (AREA)
- Water Supply & Treatment (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762459893P | 2017-02-16 | 2017-02-16 | |
| PCT/US2018/018123 WO2018152165A1 (en) | 2017-02-16 | 2018-02-14 | Excipient compounds for protein processing |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP3582801A1 EP3582801A1 (en) | 2019-12-25 |
| EP3582801A4 true EP3582801A4 (en) | 2020-12-23 |
Family
ID=63170449
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP18754459.8A Withdrawn EP3582801A4 (en) | 2017-02-16 | 2018-02-14 | ADDITIVE COMPOUNDS FOR PROTEIN PROCESSING |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP3582801A4 (en) |
| JP (1) | JP2020507593A (en) |
| KR (1) | KR102572453B1 (en) |
| CA (1) | CA3053909A1 (en) |
| WO (1) | WO2018152165A1 (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10478498B2 (en) | 2014-06-20 | 2019-11-19 | Reform Biologics, Llc | Excipient compounds for biopolymer formulations |
| WO2015196091A1 (en) | 2014-06-20 | 2015-12-23 | Reform Biologics, Llc | Viscosity-reducing excipient compounds for protein formulations |
| CN112040931A (en) * | 2018-03-07 | 2020-12-04 | 改进生物制品有限责任公司 | Excipient Compounds for Protein Formulations |
| KR20210096633A (en) * | 2018-11-29 | 2021-08-05 | 리폼 바이오로직스, 엘엘씨 | Excipient compounds for protein processing |
| TWI871300B (en) * | 2019-01-28 | 2025-02-01 | 美商安進公司 | A continuous manufacturing process for biologics manufacturing by integration of drug substance and drug product processes |
| WO2021064079A1 (en) * | 2019-10-04 | 2021-04-08 | Merck Patent Gmbh | Purification of proteins and viral inactivation |
| CN113621360A (en) * | 2020-05-06 | 2021-11-09 | 中国石油化工股份有限公司 | Thick oil viscosity reducer and application thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5710311B2 (en) * | 2011-02-18 | 2015-04-30 | 株式会社日立製作所 | Addition medium addition control method and cell culture apparatus using the method |
| AU2012328524B2 (en) * | 2011-10-28 | 2017-05-18 | Excelse Bio, Inc. | Protein formulations containing amino acids |
| EP2682168A1 (en) * | 2012-07-02 | 2014-01-08 | Millipore Corporation | Purification of biological molecules |
| IL312865B2 (en) * | 2013-09-11 | 2025-06-01 | Eagle Biologics Inc | Liquid protein formulations containing viscosity-reducing agents |
| WO2015196091A1 (en) * | 2014-06-20 | 2015-12-23 | Reform Biologics, Llc | Viscosity-reducing excipient compounds for protein formulations |
| MX391067B (en) * | 2014-10-01 | 2025-03-21 | Eagle Biologics Inc | FORMULATIONS OF POLYSACCHARIDES AND NUCLEIC ACID CONTAINING VISCOSITY REDUCING AGENTS. |
-
2018
- 2018-02-14 KR KR1020197026671A patent/KR102572453B1/en active Active
- 2018-02-14 JP JP2019543842A patent/JP2020507593A/en active Pending
- 2018-02-14 WO PCT/US2018/018123 patent/WO2018152165A1/en not_active Ceased
- 2018-02-14 EP EP18754459.8A patent/EP3582801A4/en not_active Withdrawn
- 2018-02-14 CA CA3053909A patent/CA3053909A1/en active Pending
Non-Patent Citations (1)
| Title |
|---|
| No further relevant documents disclosed * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2020507593A (en) | 2020-03-12 |
| EP3582801A1 (en) | 2019-12-25 |
| WO2018152165A1 (en) | 2018-08-23 |
| CA3053909A1 (en) | 2018-08-23 |
| KR102572453B1 (en) | 2023-08-29 |
| KR20190117631A (en) | 2019-10-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
| 17P | Request for examination filed |
Effective date: 20190905 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
| AX | Request for extension of the european patent |
Extension state: BA ME |
|
| DAV | Request for validation of the european patent (deleted) | ||
| DAX | Request for extension of the european patent (deleted) | ||
| REG | Reference to a national code |
Ref country code: DE Ref legal event code: R079 Free format text: PREVIOUS MAIN CLASS: A61K0038160000 Ipc: C07K0001340000 |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20201120 |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: C07K 16/00 20060101ALI20201116BHEP Ipc: A61K 39/395 20060101ALI20201116BHEP Ipc: C07K 1/22 20060101ALI20201116BHEP Ipc: A61K 38/16 20060101ALI20201116BHEP Ipc: C07K 1/34 20060101AFI20201116BHEP |
|
| RAP3 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: REFORM BIOLOGICS, INC. |
|
| RAP3 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: COMERA LIFE SCIENCES, INC. |
|
| P01 | Opt-out of the competence of the unified patent court (upc) registered |
Effective date: 20230516 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |
|
| 17Q | First examination report despatched |
Effective date: 20230912 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
| 18D | Application deemed to be withdrawn |
Effective date: 20240903 |