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EP3582801A4 - ADDITIVE COMPOUNDS FOR PROTEIN PROCESSING - Google Patents

ADDITIVE COMPOUNDS FOR PROTEIN PROCESSING Download PDF

Info

Publication number
EP3582801A4
EP3582801A4 EP18754459.8A EP18754459A EP3582801A4 EP 3582801 A4 EP3582801 A4 EP 3582801A4 EP 18754459 A EP18754459 A EP 18754459A EP 3582801 A4 EP3582801 A4 EP 3582801A4
Authority
EP
European Patent Office
Prior art keywords
protein processing
additive compounds
additive
compounds
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP18754459.8A
Other languages
German (de)
French (fr)
Other versions
EP3582801A1 (en
Inventor
David S. Soane
Philip Wuthrich
Robert P. Mahoney
Mark Moody
Daniel G. GREENE
Neil L. Schauer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Comera Life Sciences Inc
Original Assignee
Reform Biologics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reform Biologics Inc filed Critical Reform Biologics Inc
Publication of EP3582801A1 publication Critical patent/EP3582801A1/en
Publication of EP3582801A4 publication Critical patent/EP3582801A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/22Affinity chromatography or related techniques based upon selective absorption processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591Stabilisation, fragmentation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/34Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/36Extraction; Separation; Purification by a combination of two or more processes of different types
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Water Supply & Treatment (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
EP18754459.8A 2017-02-16 2018-02-14 ADDITIVE COMPOUNDS FOR PROTEIN PROCESSING Withdrawn EP3582801A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762459893P 2017-02-16 2017-02-16
PCT/US2018/018123 WO2018152165A1 (en) 2017-02-16 2018-02-14 Excipient compounds for protein processing

Publications (2)

Publication Number Publication Date
EP3582801A1 EP3582801A1 (en) 2019-12-25
EP3582801A4 true EP3582801A4 (en) 2020-12-23

Family

ID=63170449

Family Applications (1)

Application Number Title Priority Date Filing Date
EP18754459.8A Withdrawn EP3582801A4 (en) 2017-02-16 2018-02-14 ADDITIVE COMPOUNDS FOR PROTEIN PROCESSING

Country Status (5)

Country Link
EP (1) EP3582801A4 (en)
JP (1) JP2020507593A (en)
KR (1) KR102572453B1 (en)
CA (1) CA3053909A1 (en)
WO (1) WO2018152165A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10478498B2 (en) 2014-06-20 2019-11-19 Reform Biologics, Llc Excipient compounds for biopolymer formulations
WO2015196091A1 (en) 2014-06-20 2015-12-23 Reform Biologics, Llc Viscosity-reducing excipient compounds for protein formulations
CN112040931A (en) * 2018-03-07 2020-12-04 改进生物制品有限责任公司 Excipient Compounds for Protein Formulations
KR20210096633A (en) * 2018-11-29 2021-08-05 리폼 바이오로직스, 엘엘씨 Excipient compounds for protein processing
TWI871300B (en) * 2019-01-28 2025-02-01 美商安進公司 A continuous manufacturing process for biologics manufacturing by integration of drug substance and drug product processes
WO2021064079A1 (en) * 2019-10-04 2021-04-08 Merck Patent Gmbh Purification of proteins and viral inactivation
CN113621360A (en) * 2020-05-06 2021-11-09 中国石油化工股份有限公司 Thick oil viscosity reducer and application thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5710311B2 (en) * 2011-02-18 2015-04-30 株式会社日立製作所 Addition medium addition control method and cell culture apparatus using the method
AU2012328524B2 (en) * 2011-10-28 2017-05-18 Excelse Bio, Inc. Protein formulations containing amino acids
EP2682168A1 (en) * 2012-07-02 2014-01-08 Millipore Corporation Purification of biological molecules
IL312865B2 (en) * 2013-09-11 2025-06-01 Eagle Biologics Inc Liquid protein formulations containing viscosity-reducing agents
WO2015196091A1 (en) * 2014-06-20 2015-12-23 Reform Biologics, Llc Viscosity-reducing excipient compounds for protein formulations
MX391067B (en) * 2014-10-01 2025-03-21 Eagle Biologics Inc FORMULATIONS OF POLYSACCHARIDES AND NUCLEIC ACID CONTAINING VISCOSITY REDUCING AGENTS.

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
No further relevant documents disclosed *

Also Published As

Publication number Publication date
JP2020507593A (en) 2020-03-12
EP3582801A1 (en) 2019-12-25
WO2018152165A1 (en) 2018-08-23
CA3053909A1 (en) 2018-08-23
KR102572453B1 (en) 2023-08-29
KR20190117631A (en) 2019-10-16

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