EP3579868A4 - Composition immunogène pour moduler le système immunitaire et procédés pour traiter des infections bactériennes chez un sujet - Google Patents

Composition immunogène pour moduler le système immunitaire et procédés pour traiter des infections bactériennes chez un sujet Download PDF

Info

Publication number: EP3579868A4
Authority: EP; European Patent Office
Prior art keywords: modulating; subject; methods; immune system; immunogenic composition
Prior art date: 2017-02-13
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

EP18751350.2A

Other languages

German (de)

English (en)

Other versions

EP3579868A1 (fr

Inventor

Alexandre Eduardo NOWILL

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Individual

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2017-02-13

Filing date

2018-02-15

Publication date

2021-01-06

2017-02-13 Priority claimed from US15/431,329 external-priority patent/US10213504B2/en

2018-02-15 Application filed by Individual filed Critical Individual

2019-12-18 Publication of EP3579868A1 publication Critical patent/EP3579868A1/fr

2021-01-06 Publication of EP3579868A4 publication Critical patent/EP3579868A4/fr

Status Pending legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/396—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having three-membered rings, e.g. aziridine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K39/275—Poxviridae, e.g. avipoxvirus
- A61K39/285—Vaccinia virus or variola virus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Epidemiology (AREA)
Mycology (AREA)
Microbiology (AREA)
Virology (AREA)
Communicable Diseases (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Oncology (AREA)
Pulmonology (AREA)
Engineering & Computer Science (AREA)
Tropical Medicine & Parasitology (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

EP18751350.2A 2017-02-13 2018-02-15 Composition immunogène pour moduler le système immunitaire et procédés pour traiter des infections bactériennes chez un sujet Pending EP3579868A4 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US15/431,329 US10213504B2 (en)	2011-03-18	2017-02-13	Immunogenic composition for modulating the immune system and methods to treat bacterial infections in a subject
PCT/BR2018/000004 WO2018145180A1 (fr)	2017-02-13	2018-02-15	Composition immunogène pour moduler le système immunitaire et procédés pour traiter des infections bactériennes chez un sujet

Publications (2)

Publication Number	Publication Date
EP3579868A1 EP3579868A1 (fr)	2019-12-18
EP3579868A4 true EP3579868A4 (fr)	2021-01-06

Family

ID=63106848

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP18751350.2A Pending EP3579868A4 (fr)	2017-02-13	2018-02-15	Composition immunogène pour moduler le système immunitaire et procédés pour traiter des infections bactériennes chez un sujet

Country Status (10)

Country	Link
EP (1)	EP3579868A4 (fr)
JP (1)	JP2020507629A (fr)
KR (1)	KR20190139209A (fr)
CN (1)	CN110709099B (fr)
AU (1)	AU2018217441B2 (fr)
BR (1)	BR112019016670A2 (fr)
IL (1)	IL268626B2 (fr)
MX (1)	MX2019009689A (fr)
RU (1)	RU2019128674A (fr)
WO (1)	WO2018145180A1 (fr)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2687227A1 (fr) *	2011-03-18	2014-01-22	Nowill, Alexandre Eduardo	Composition immunogène pour modulation du système immunitaire et son utilisation, méthode de traitement et de prévention de maladies, méthode destinée à induire la régénération cellulaire et méthode de rétablissement de la réponse immunitaire

Family Cites Families (8)

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Publication number	Priority date	Publication date	Assignee	Title
EP1617867B1 (fr) *	2003-04-30	2011-10-26	Medi Service S.R.L.	Composition immunomodulatrice contenant une fraction de particules de lysats mecaniques bacteriens
WO2005077408A2 (fr) *	2004-02-06	2005-08-25	Vaxinnate Corporation	Compositions de modele moleculaire associe a un pathogene (pamp) et monocytogenes listeria et leurs procedes d'utilisation
WO2008020330A2 (fr) *	2006-08-16	2008-02-21	Novartis Ag	Immunogènes pour escherichia coli uropathogène
EP1938835A1 (fr) *	2006-12-29	2008-07-02	Pevion Biotech AG	Agent immunostimulant non spécifique
AU2009266940A1 (en) *	2008-07-01	2010-01-07	Emory University	Synergistic induction of humoral and cellular immunity by combinatorial activation of toll-like receptors
WO2011004263A2 (fr) *	2009-07-07	2011-01-13	Novartis Ag	Immunogènes d' escherichia coli conservés
HRP20141270T1 (xx) *	2009-07-16	2015-03-13	Novartis Ag	Detoksificirani imunogeni escherichie coli
US8980279B2 (en) *	2010-07-26	2015-03-17	Qu Biologics	Personalized site-specific immunomodulation

2018
- 2018-02-15 BR BR112019016670A patent/BR112019016670A2/pt unknown
- 2018-02-15 WO PCT/BR2018/000004 patent/WO2018145180A1/fr not_active Ceased
- 2018-02-15 KR KR1020197026857A patent/KR20190139209A/ko not_active Ceased
- 2018-02-15 RU RU2019128674A patent/RU2019128674A/ru unknown
- 2018-02-15 IL IL268626A patent/IL268626B2/en unknown
- 2018-02-15 AU AU2018217441A patent/AU2018217441B2/en active Active
- 2018-02-15 JP JP2019564565A patent/JP2020507629A/ja active Pending
- 2018-02-15 MX MX2019009689A patent/MX2019009689A/es unknown
- 2018-02-15 CN CN201880023729.7A patent/CN110709099B/zh active Active
- 2018-02-15 EP EP18751350.2A patent/EP3579868A4/fr active Pending

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2687227A1 (fr) *	2011-03-18	2014-01-22	Nowill, Alexandre Eduardo	Composition immunogène pour modulation du système immunitaire et son utilisation, méthode de traitement et de prévention de maladies, méthode destinée à induire la régénération cellulaire et méthode de rétablissement de la réponse immunitaire

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ALEXANDRE E. NOWILL ET AL: "Immune Response Resetting in Ongoing Sepsis", THE JOURNAL OF IMMUNOLOGY, vol. 203, no. 5, 29 July 2019 (2019-07-29), US, pages 1298 - 1312, XP055753436, ISSN: 0022-1767, DOI: 10.4049/jimmunol.1900104 *
See also references of WO2018145180A1 *

Also Published As

Publication number	Publication date
IL268626A (en)	2019-10-31
CN110709099A (zh)	2020-01-17
RU2019128674A (ru)	2021-03-16
IL268626B2 (en)	2024-04-01
KR20190139209A (ko)	2019-12-17
WO2018145180A1 (fr)	2018-08-16
IL268626B1 (en)	2023-12-01
BR112019016670A2 (pt)	2020-04-14
AU2018217441B2 (en)	2024-11-07
MX2019009689A (es)	2019-12-18
EP3579868A1 (fr)	2019-12-18
CN110709099B (zh)	2024-03-29
JP2020507629A (ja)	2020-03-12
RU2019128674A3 (fr)	2021-06-18
AU2018217441A1 (en)	2019-10-03

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