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EP3560490A4 - ORAL IBUPROFEN PREPARATION - Google Patents

ORAL IBUPROFEN PREPARATION Download PDF

Info

Publication number
EP3560490A4
EP3560490A4 EP17883760.5A EP17883760A EP3560490A4 EP 3560490 A4 EP3560490 A4 EP 3560490A4 EP 17883760 A EP17883760 A EP 17883760A EP 3560490 A4 EP3560490 A4 EP 3560490A4
Authority
EP
European Patent Office
Prior art keywords
oral ibuprofen
ibuprofen preparation
preparation
oral
ibuprofen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP17883760.5A
Other languages
German (de)
French (fr)
Other versions
EP3560490A1 (en
EP3560490B1 (en
EP3560490C0 (en
Inventor
Tomihisa Yamaguchi
Makoto Umino
Nobuo Miyadai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SSP Co Ltd
Original Assignee
SSP Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SSP Co Ltd filed Critical SSP Co Ltd
Publication of EP3560490A1 publication Critical patent/EP3560490A1/en
Publication of EP3560490A4 publication Critical patent/EP3560490A4/en
Application granted granted Critical
Publication of EP3560490B1 publication Critical patent/EP3560490B1/en
Publication of EP3560490C0 publication Critical patent/EP3560490C0/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/08Oxides; Hydroxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1611Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Biophysics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP17883760.5A 2016-12-22 2017-12-22 Oral ibuprofen preparation Active EP3560490B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2016249261A JP2018104299A (en) 2016-12-22 2016-12-22 Oral ibuprofen formulation
PCT/JP2017/046056 WO2018117249A1 (en) 2016-12-22 2017-12-22 Oral ibuprofen preparation

Publications (4)

Publication Number Publication Date
EP3560490A1 EP3560490A1 (en) 2019-10-30
EP3560490A4 true EP3560490A4 (en) 2020-08-26
EP3560490B1 EP3560490B1 (en) 2024-11-06
EP3560490C0 EP3560490C0 (en) 2024-11-06

Family

ID=62626626

Family Applications (1)

Application Number Title Priority Date Filing Date
EP17883760.5A Active EP3560490B1 (en) 2016-12-22 2017-12-22 Oral ibuprofen preparation

Country Status (7)

Country Link
EP (1) EP3560490B1 (en)
JP (1) JP2018104299A (en)
AU (1) AU2017384442B2 (en)
HU (1) HUE070029T2 (en)
MX (1) MX2019007529A (en)
RU (1) RU2751351C2 (en)
WO (1) WO2018117249A1 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0465235A1 (en) * 1990-07-03 1992-01-08 McNEIL-PPC, INC. Pharmaceutical compositions and methods for alleviating gastrointestinal symptoms induced by nonsteroidal anti-inflammatory drugs

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2704721B2 (en) * 1987-02-12 1998-01-26 ライオン株式会社 Ibuprofen formulation
JPH01294619A (en) * 1988-02-16 1989-11-28 Sanwa Kagaku Kenkyusho Co Ltd Glycyrrhetin preparation
JP3717189B2 (en) * 1992-01-27 2005-11-16 ダイト株式会社 Analgesic anti-inflammatory agent
JP2000264838A (en) * 1999-03-16 2000-09-26 Taiho Yakuhin Kogyo Kk Processed ibuprofen powder and solid preparation containing it
JP5296968B2 (en) * 2005-06-17 2013-09-25 第一三共ヘルスケア株式会社 Oral pharmaceutical composition containing ibuprofen
JP2007084514A (en) * 2005-09-26 2007-04-05 Gunma Univ Glycyrrhizin preparation for inflammatory bowel disease
JP2010270042A (en) * 2009-05-20 2010-12-02 Kowa Co Method for stabilizing glycyrrhizic acid
JP5959393B2 (en) * 2012-09-27 2016-08-02 小林製薬株式会社 Pharmaceutical composition containing phenylpropionic acid anti-inflammatory analgesic
JP6117591B2 (en) * 2013-03-29 2017-04-19 小林製薬株式会社 Pharmaceutical composition containing mosapride and an antacid

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0465235A1 (en) * 1990-07-03 1992-01-08 McNEIL-PPC, INC. Pharmaceutical compositions and methods for alleviating gastrointestinal symptoms induced by nonsteroidal anti-inflammatory drugs

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
OKABE S ET AL: "Effects of Fm100, Fm 100-DeG and glycyrrhizin on gastric secretion and experimental gastriculcers in rats", OYO YAKURI - PHARMACOMETRICS, OYO YAKURI KENKYUKAI, JP, vol. 18, no. 3, 1 January 1979 (1979-01-01), pages 469 - 474, XP009521469, ISSN: 0300-8533 *

Also Published As

Publication number Publication date
RU2019122120A3 (en) 2021-02-10
AU2017384442A1 (en) 2019-07-04
AU2017384442B2 (en) 2022-12-08
BR112019012932A2 (en) 2019-12-10
MX2019007529A (en) 2019-08-16
HUE070029T2 (en) 2025-05-28
EP3560490A1 (en) 2019-10-30
EP3560490B1 (en) 2024-11-06
EP3560490C0 (en) 2024-11-06
RU2019122120A (en) 2021-01-22
WO2018117249A1 (en) 2018-06-28
RU2751351C2 (en) 2021-07-13
JP2018104299A (en) 2018-07-05

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