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EP3494377A1 - Élément à échantillon - Google Patents

Élément à échantillon

Info

Publication number
EP3494377A1
EP3494377A1 EP17780203.0A EP17780203A EP3494377A1 EP 3494377 A1 EP3494377 A1 EP 3494377A1 EP 17780203 A EP17780203 A EP 17780203A EP 3494377 A1 EP3494377 A1 EP 3494377A1
Authority
EP
European Patent Office
Prior art keywords
resins
sample element
resinous material
element according
gma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP17780203.0A
Other languages
German (de)
English (en)
Inventor
Stefano COLLISELLI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP3494377A1 publication Critical patent/EP3494377A1/fr
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor

Definitions

  • the present invention relates to a sample element.
  • the present invention is advantageously applied for the realization of a sample or simulation element suitable for use in the process of controlling and validating production processes, in particular of primary packaging machines in the pharmaceutical sector, the following description being made with explicit reference without losing its generality.
  • the purpose of the present invention is therefore to overcome the drawbacks of the known art disclosed above.
  • the purpose of the present invention is to provide sample element which has a simple construction, is safe and has high quality and durability.
  • Another purpose of the present invention is to provide a sample element with high durability against wear, high compressive strength and high resistance to the great stresses imposed within the primary packaging machines of which production performances must be tested.
  • FIG. 2 is a schematic sectional view of a second embodiment of a sample element in question.
  • E globally a sample or simulation element is indicated which is able to be supplied and introduced into primary packaging machines, in a preferable but not limited way by the pharmaceutical sector, in order to monitor and test the quality and/or validation of the machines themselves and their production processes.
  • the sample element E in the purely indicative examples of Figures 1 and 2, is a vial or similar container used to contain liquid substances in the pharmaceutical sector which is made of a single body C through molding of a resinous material with components resistant to bacterial colonization and specially designed to be fed/cold- pressed and pressurized within a mold of a predefined shape and preferably made of a metal material.
  • the cold-fed resinous material gives to the element E high hardness, aesthetic validity, very high polishing quality, high wear resistance, high biocompatible mechanical and thermal performances, and also a previously selected and variable color, in order to permit an easy and quick detection of element E during control phases.
  • the cited resinous material may include acrylic resins, including PMMA-based resins, hydrophilic acrylic resins modified with hydroxyl methyl methacrylate, by copolymerization of MMA with hydroxyl methyl methacrylate, vinyl acrylic copolymers (vinyl chloride powder or vinyl acetate, liquid-based MMA), component substances such as dimethyl methacrylate F, Xi, N, N-dimethyl-p-toluidine T, N/A- polymethyl methacrylate, N/A-diethyl phthalate, dibenzoyl peroxide E, Xi.
  • acrylic resins including PMMA-based resins, hydrophilic acrylic resins modified with hydroxyl methyl methacrylate, by copolymerization of MMA with hydroxyl methyl methacrylate, vinyl acrylic copolymers (vinyl chloride powder or vinyl acetate, liquid-based MMA), component substances such as dimethyl methacrylate F, Xi, N, N-dimethyl-p-
  • the resinous material may include composite resins, including conventional composite resins, micro-filled composite resins (barium glasses, quartz and pyrogenic silica), micro-particulate resin complexes, mixed-filled composite resins.
  • composite resins including conventional composite resins, micro-filled composite resins (barium glasses, quartz and pyrogenic silica), micro-particulate resin complexes, mixed-filled composite resins.
  • the resinous material may include light-curing resins (BIS- GMA, UDMA and TEGDMA), i.e. either a synthesized chemical compound (BIS- GMA) treated with various diluents, or triethylene glycol dimethacrylate (TEGDMA) or ethylene glycol methacrylate (EGDMA) or di-urethane-di-methacrylate (DUEDMA), or bisphenol-A methcrylate (BIS-GMA), or methyl methacrylate (MMA).
  • a synthesized chemical compound TEGDMA
  • EGDMA ethylene glycol methacrylate
  • DUEDMA di-urethane-di-methacrylate
  • MMA methyl methacrylate
  • the resinous material may include self-cured resins, synthetic resins, artificial resins with fillers, epoxy resins, polyurethane resins with specific dyes (stabilized methyl methacrylate).
  • the element E then has integrated control sensor means S, at different selected points of the element E itself ( Figures 1 and 2), such as resistors, temperature probes, pressure probes, inserts detectable by external analysis systems (such as cameras, metal detectors, X-rays, etc.) or equivalent.
  • integrated control sensor means S such as resistors, temperature probes, pressure probes, inserts detectable by external analysis systems (such as cameras, metal detectors, X-rays, etc.) or equivalent.
  • the sensors S will therefore be integrated in a single body with the same element E, in order to guarantee technical characteristics and high strength, high wear life, high compressive strength and high resistance to the considerable stresses imposed within the primary packaging machines.

Landscapes

  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Dental Preparations (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Thyristors (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)

Abstract

Un élément à échantillon (E) comprend un corps (C) unique constitué d'une matière résineuse et supportant un moyen formant capteur de commande (S) noyé dans ledit corps (C).
EP17780203.0A 2016-08-04 2017-07-31 Élément à échantillon Ceased EP3494377A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT102016000082156A IT201600082156A1 (it) 2016-08-04 2016-08-04 Elemento campione di controllo di un processo produttivo.
PCT/IB2017/054656 WO2018025161A1 (fr) 2016-08-04 2017-07-31 Élément à échantillon

Publications (1)

Publication Number Publication Date
EP3494377A1 true EP3494377A1 (fr) 2019-06-12

Family

ID=57708681

Family Applications (1)

Application Number Title Priority Date Filing Date
EP17780203.0A Ceased EP3494377A1 (fr) 2016-08-04 2017-07-31 Élément à échantillon

Country Status (3)

Country Link
EP (1) EP3494377A1 (fr)
IT (1) IT201600082156A1 (fr)
WO (1) WO2018025161A1 (fr)

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3829221A (en) * 1972-02-29 1974-08-13 M Dupuy Apparatus for automatically measuring the light transmission factor or liquid test samples
US5439036A (en) * 1993-03-29 1995-08-08 Kraemer; Norbert Method and apparatus for the automatic checking and quality determination of tablets or pills
US6143573A (en) * 1994-07-11 2000-11-07 Tekmar Company Modular vial autosampler
WO2003050513A2 (fr) * 2001-12-06 2003-06-19 Biocontrol Systems, Inc. Systeme de recuperation et d'analyse d'echantillons
US6943692B2 (en) * 2001-02-02 2005-09-13 Bristol-Myers Squibb Pharma Company Apparatus and methods for on-line monitoring of fluorinated material in headspace of vial
US20060145863A1 (en) * 2004-12-20 2006-07-06 Jean-Paul Martin RFID tag with visual environmental condition monitor
US20070203650A1 (en) * 2006-02-28 2007-08-30 Jensen Thomas P Environmental sensing
US20120274470A1 (en) * 2009-12-11 2012-11-01 Sandvick Warren J Food safety indicator
US20150307245A1 (en) * 2014-04-24 2015-10-29 Steven D. Puccini Intelligent wine capsule
EP3100974A1 (fr) * 2015-06-05 2016-12-07 Anheuser-Busch InBev S.A. Procédé de commande d'un protocole de gestion d'éclatement de bouteille d'un dispositif de remplissage de récipient et conteneur factice appliqué à cet effet

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0637290Y2 (ja) * 1991-06-14 1994-09-28 スタンレー電気株式会社 カプラ一体型センサ
JP3862770B2 (ja) * 1995-09-07 2006-12-27 日立化成工業株式会社 金属張積層板の製造方法
JP5359549B2 (ja) * 2008-05-30 2013-12-04 新日鐵住金株式会社 ベルレス高炉における原料装入状況の把握方法および高炉の操業方法
JP5307852B2 (ja) * 2011-05-19 2013-10-02 三菱電機株式会社 温度センサ
WO2015129291A1 (fr) * 2014-02-26 2015-09-03 学校法人 関西大学 Procédé de production de polymère piézoélectrique

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3829221A (en) * 1972-02-29 1974-08-13 M Dupuy Apparatus for automatically measuring the light transmission factor or liquid test samples
US5439036A (en) * 1993-03-29 1995-08-08 Kraemer; Norbert Method and apparatus for the automatic checking and quality determination of tablets or pills
US6143573A (en) * 1994-07-11 2000-11-07 Tekmar Company Modular vial autosampler
US6943692B2 (en) * 2001-02-02 2005-09-13 Bristol-Myers Squibb Pharma Company Apparatus and methods for on-line monitoring of fluorinated material in headspace of vial
WO2003050513A2 (fr) * 2001-12-06 2003-06-19 Biocontrol Systems, Inc. Systeme de recuperation et d'analyse d'echantillons
JP2006502376A (ja) * 2001-12-06 2006-01-19 バイオコントロール システムズ，インコーポレイティド サンプル収集および試験システム
US20060145863A1 (en) * 2004-12-20 2006-07-06 Jean-Paul Martin RFID tag with visual environmental condition monitor
US20070203650A1 (en) * 2006-02-28 2007-08-30 Jensen Thomas P Environmental sensing
US20120274470A1 (en) * 2009-12-11 2012-11-01 Sandvick Warren J Food safety indicator
US20150307245A1 (en) * 2014-04-24 2015-10-29 Steven D. Puccini Intelligent wine capsule
EP3100974A1 (fr) * 2015-06-05 2016-12-07 Anheuser-Busch InBev S.A. Procédé de commande d'un protocole de gestion d'éclatement de bouteille d'un dispositif de remplissage de récipient et conteneur factice appliqué à cet effet

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ANONYMOUS E A: "Fraunhofer ENAS Annual Report 2009", 1 January 2009 (2009-01-01), Chemnitz, GERMANY, pages 1 - 97, XP093019135, Retrieved from the Internet <URL:https://www.enas.fraunhofer.de/content/dam/enas/Dokumente/Deutsch/Downloads/Jahresberichte/Jahresbericht2009_FraunhoferENAS_web.pdf> [retrieved on 20230130] *
ANONYMOUS: "Annex 4 WHO guidelines for sampling of pharmaceutical products and related materials", 1 January 2005 (2005-01-01), pages 1 - 35, XP093094979, Retrieved from the Internet <URL:https://www.who.int/docs/default-source/medicines/norms-and-standards/guidelines/quality-control/trs929-annex4-guidelinessamplingpharmproducts.pdf?sfvrsn=f6273f30_2> [retrieved on 20231025] *
See also references of WO2018025161A1 *

Also Published As

Publication number Publication date
WO2018025161A1 (fr) 2018-02-08
IT201600082156A1 (it) 2018-02-04

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