EP3452036A4 - USE OF TOPICAL FORMULATIONS OF CANNABINOIDS FOR THE TREATMENT OF BLEED EPIDERMOLYSIS AND RELATED CONNECTIVE TISSUE DISORDERS - Google Patents
USE OF TOPICAL FORMULATIONS OF CANNABINOIDS FOR THE TREATMENT OF BLEED EPIDERMOLYSIS AND RELATED CONNECTIVE TISSUE DISORDERS Download PDFInfo
- Publication number
- EP3452036A4 EP3452036A4 EP17792340.6A EP17792340A EP3452036A4 EP 3452036 A4 EP3452036 A4 EP 3452036A4 EP 17792340 A EP17792340 A EP 17792340A EP 3452036 A4 EP3452036 A4 EP 3452036A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- epidermolysis
- cannabinoids
- bleed
- treatment
- connective tissue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/658—Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Furan Compounds (AREA)
- Pyrane Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662331633P | 2016-05-04 | 2016-05-04 | |
| PCT/CA2017/050546 WO2017190249A1 (en) | 2016-05-04 | 2017-05-04 | Use of topical formulations of cannabinoids in the treatment of epidermolysis bullosa and related connective tissue disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP3452036A1 EP3452036A1 (en) | 2019-03-13 |
| EP3452036A4 true EP3452036A4 (en) | 2019-11-06 |
Family
ID=60202544
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP17792340.6A Pending EP3452036A4 (en) | 2016-05-04 | 2017-05-04 | USE OF TOPICAL FORMULATIONS OF CANNABINOIDS FOR THE TREATMENT OF BLEED EPIDERMOLYSIS AND RELATED CONNECTIVE TISSUE DISORDERS |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US12042479B2 (en) |
| EP (1) | EP3452036A4 (en) |
| JP (2) | JP7054691B2 (en) |
| CN (1) | CN109689045A (en) |
| AU (1) | AU2017260706B2 (en) |
| CA (1) | CA3023049A1 (en) |
| IL (1) | IL262702B (en) |
| SG (1) | SG11201809688RA (en) |
| WO (1) | WO2017190249A1 (en) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10640464B2 (en) | 2011-01-03 | 2020-05-05 | The William M. Yarbrough Foundation | Use of isothiocyanate functional surfactants as Nrf2 inducers to treat epidermolysis bullosa simplex and related diseases |
| AU2017260706B2 (en) | 2016-05-04 | 2023-05-11 | Inmed Pharmaceuticals Inc. | Use of topical formulations of cannabinoids in the treatment of epidermolysis bullosa and related connective tissue disorders |
| CA3052146A1 (en) * | 2017-02-01 | 2018-08-09 | Gbs Global Biopharma, Inc. | Cannabinoid-containing complex mixtures for the treatment of mast cell-associated or basophil-mediated inflammatory disorders |
| US11318179B2 (en) * | 2017-06-20 | 2022-05-03 | Jessica Kado | Topical formulation for binding to dermatological cannabinoid receptors |
| WO2019056123A1 (en) * | 2017-09-22 | 2019-03-28 | Inmed Pharmaceuticals Inc. | Topical formulations of cannabinoids and use thereof in the treatment of pain |
| WO2019191830A1 (en) | 2018-04-04 | 2019-10-10 | Vincenzo Maida | Topical cannabinoid formulations and instillates, kits, and methods for treating integumentary wounds, and uses thereof |
| WO2020051284A1 (en) * | 2018-09-05 | 2020-03-12 | Nemus Bioscience, Inc. | Cannabinoids for the treatment of gram-positive infections including antibiotic-resistant bacterial strains |
| EP3643303A1 (en) * | 2018-10-22 | 2020-04-29 | InnovativeHealth Group SL | Compounds for use in the treatment or prevention of fibrotic diseases; pharmaceutical, cosmetic compositions and uses thereof |
| WO2020142692A1 (en) * | 2019-01-04 | 2020-07-09 | Columbia Care Llc | Topical formulations having cannabinoid |
| CA3130763A1 (en) | 2019-02-25 | 2020-09-03 | Ginkgo Bioworks, Inc. | Biosynthesis of cannabinoids and cannabinoid precursors |
| WO2020234650A1 (en) * | 2019-05-21 | 2020-11-26 | Timeless Herbal Care (Canada) Ltd. | Pharmaceutical compositions comprising cbd and terpene compositions |
| CA3057647A1 (en) * | 2019-10-03 | 2021-04-03 | Vinsan Therapeutics Inc. | Topical formulations and instillates, kits, and methods for treating integumentary wounds, and uses thereof |
| US11160768B2 (en) | 2019-10-22 | 2021-11-02 | Edmund M. Dunn | Paraffin wax with CBD isolate |
| CN113116870A (en) * | 2019-12-31 | 2021-07-16 | 四川大学 | Application of cannabidiol in preparation of medicine for promoting oral mucosa healing |
| US20210236687A1 (en) * | 2020-01-31 | 2021-08-05 | Pac-Dent, Inc. | Cannabinoid-based oral hemostatic compositions |
| MX2022009507A (en) * | 2020-02-06 | 2022-11-09 | London Pharmaceuticals And Res Corporation | SULFATE ESTERS OF CANNABINOIDS, THEIR SALTS AND USES THEREOF. |
| EP4430023A1 (en) * | 2021-11-10 | 2024-09-18 | London Pharmaceuticals and Research Corporation | New cannabinoid-gabapentinoid conjugates and uses thereof |
| KR20250109184A (en) * | 2022-09-19 | 2025-07-16 | 브라이트씨드, 인크. | Compositions and methods for improving intestinal permeability |
| WO2024108201A2 (en) * | 2022-11-18 | 2024-05-23 | Bazelet Health Systems, Inc. | Cannabigerolic acid (cbga) and cannabigerol (cbg) derived products and methods of use |
| CN116602268B (en) * | 2023-02-24 | 2024-01-05 | 中国医学科学院皮肤病医院(中国医学科学院皮肤病研究所) | Application of gene knockout mutant zebrafish in preparing animal models of pigmentation reduction |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010013240A1 (en) * | 2008-07-31 | 2010-02-04 | Dekel Pharmaceuticals Ltd. | Compositions and methods for treating inflammatory disorders |
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| DE19706903A1 (en) | 1997-02-21 | 1998-08-27 | Bayer Ag | Use of known agonists of the central cannabinoid receptor CB 1 |
| EP1645270B1 (en) | 1998-05-29 | 2010-04-28 | Neurosciences Research Foundation Inc. | Control of pain with ANANDAMIDE |
| JP2002520282A (en) | 1998-07-09 | 2002-07-09 | フランシス エイ. ナーデラ, | Methods and compositions for the treatment of chronic lymphocytic leukemia |
| US6566560B2 (en) | 1999-03-22 | 2003-05-20 | Immugen Pharmaceuticals, Inc. | Resorcinolic compounds |
| US6921722B2 (en) | 2000-05-30 | 2005-07-26 | Ebara Corporation | Coating, modification and etching of substrate surface with particle beam irradiation of the same |
| US8449908B2 (en) | 2000-12-22 | 2013-05-28 | Alltranz, Llc | Transdermal delivery of cannabidiol |
| US7109216B2 (en) | 2001-09-21 | 2006-09-19 | Solvay Pharmaceuticals B.V. | 1H-imidazole derivatives having CB1 agonistic, CB1 partial agonistic or CB1-antagonistic activity |
| US6825209B2 (en) | 2002-04-15 | 2004-11-30 | Research Triangle Institute | Compounds having unique CB1 receptor binding selectivity and methods for their production and use |
| CA2524251A1 (en) | 2003-05-01 | 2004-11-11 | Vernalis Research Limited | Azetidinecarboxamide derivatives and their use in the treatment of cb1 receptor mediated disorders |
| JP2007507523A (en) | 2003-10-02 | 2007-03-29 | セフアロン・インコーポレーテツド | Substituted indole derivatives |
| FR2864958B1 (en) | 2004-01-12 | 2006-02-24 | Sanofi Synthelabo | N - [(1,5-DIPHENYL-1H-PYRAZOL-3-YL) METHYL] SULFONAMIDE DERIVATIVE, THEIR PREPARATION AND THERAPEUTIC USE THEREOF |
| TWI330635B (en) | 2004-03-05 | 2010-09-21 | Organon Nv | (indol-3-yl)-heterocycle derivatives |
| EP1588697A1 (en) | 2004-04-16 | 2005-10-26 | Kurt H. Prof. Dr. Bauer | Emulsion gel for topical application of pharmaceuticals |
| GB2414933B (en) | 2004-06-08 | 2009-07-15 | Gw Pharma Ltd | Cannabinoid compositions for the treatment of disease and/or symptoms in arthritis |
| WO2006111424A1 (en) * | 2005-04-22 | 2006-10-26 | Life & Brain Gmbh | Methods for identifying modulators of cb1 and cb2 cannabinoid receptors and their use in wound healing |
| GB2432312A (en) | 2005-11-01 | 2007-05-23 | Gw Pharma Ltd | Pharmaceutical compositions for the treatment of pain |
| GB2439393B (en) | 2006-06-23 | 2011-05-11 | Gw Pharma Ltd | Cannabinoids for use in the treatment of neuropathic pain |
| BRPI0714199A2 (en) | 2006-07-04 | 2012-12-25 | Janssen Pharmaceutica Nv | benzimidazole cannabinoid agonists carrying a substituted heterocyclic group |
| US9394267B2 (en) | 2007-07-13 | 2016-07-19 | The Cleveland Clinic Foundation | Heterocyclic modulators of cannabinoid receptors |
| EP2424525A1 (en) | 2009-04-28 | 2012-03-07 | AllTranz Inc. | Formulations of cannabidiol and methods of using the same |
| WO2010126501A1 (en) | 2009-04-29 | 2010-11-04 | University Of Kentucky Research Foundation | Cannabinoid-containing compositions and methods for their use |
| SG10201404925TA (en) | 2009-08-28 | 2014-10-30 | Arena Pharm Inc | Cannabinoid receptor modulators |
| GB2524689B (en) | 2011-05-20 | 2016-01-27 | Gw Pharma Ltd | Cannabinoids for use in the treatment of neuropathic pain |
| US9133128B2 (en) | 2011-06-17 | 2015-09-15 | Research Triangle Institute | Pyrazole derivatives as cannabinoid receptor 1 antagonists |
| CA2866787C (en) | 2011-09-29 | 2021-05-18 | Thc Pharm Gmbh The Health Concept | Cannabinoid carboxylic acids, salts of cannabinoid carboxylic acids, and the production and uses of same |
| AU2014347807A1 (en) | 2013-10-31 | 2016-05-26 | Full Spectrum Laboratories, Ltd. | Terpene and cannabinoid formulations |
| US20160022627A2 (en) | 2014-04-18 | 2016-01-28 | Mary's Medicinals LLC | Transdermal cannabinoid patch |
| US10028904B2 (en) | 2014-12-04 | 2018-07-24 | Wisconsin Alumni Research Foundation | Transdermal cannabinoid formulations |
| US9375417B2 (en) | 2014-12-04 | 2016-06-28 | Mary's Medicinals LLC | Transdermal cannabinoid formulations |
| GB2542797A (en) * | 2015-09-29 | 2017-04-05 | Gw Pharma Ltd | Use of cannabinoids in the treatment of inflammatory skin diseases |
| PL3429580T3 (en) | 2016-03-16 | 2025-09-22 | Buzzelet Development And Technologies Ltd | CANNABINOID COMPOSITION ENRICHED WITH TERPENES |
| AU2017260706B2 (en) | 2016-05-04 | 2023-05-11 | Inmed Pharmaceuticals Inc. | Use of topical formulations of cannabinoids in the treatment of epidermolysis bullosa and related connective tissue disorders |
-
2017
- 2017-05-04 AU AU2017260706A patent/AU2017260706B2/en active Active
- 2017-05-04 US US16/098,324 patent/US12042479B2/en active Active
- 2017-05-04 WO PCT/CA2017/050546 patent/WO2017190249A1/en not_active Ceased
- 2017-05-04 JP JP2019510730A patent/JP7054691B2/en active Active
- 2017-05-04 CN CN201780041674.8A patent/CN109689045A/en active Pending
- 2017-05-04 EP EP17792340.6A patent/EP3452036A4/en active Pending
- 2017-05-04 CA CA3023049A patent/CA3023049A1/en active Pending
- 2017-05-04 SG SG11201809688RA patent/SG11201809688RA/en unknown
-
2018
- 2018-10-31 IL IL262702A patent/IL262702B/en unknown
-
2022
- 2022-04-04 JP JP2022062473A patent/JP7342183B2/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010013240A1 (en) * | 2008-07-31 | 2010-02-04 | Dekel Pharmaceuticals Ltd. | Compositions and methods for treating inflammatory disorders |
Non-Patent Citations (5)
| Title |
|---|
| ANONYMOUS: "CBD For Skin Conditions - Cannabidiol Salve, Balms, Creams", BUYCBDOILONLINE, 13 June 2014 (2014-06-13), pages 1 - 8, XP055550284, Retrieved from the Internet <URL:http://www.buycbdoilonline.info/2014/06/cbd-skin-conditions> [retrieved on 20190131] * |
| ANONYMOUS: "News Releases-InMed Pharmaceuticals", 4 November 2015 (2015-11-04), XP055784310, Retrieved from the Internet <URL:https://investors.inmedpharma.com/news-releases?item=74> [retrieved on 20210310] * |
| JOUNI UITTO ET AL: "Progress toward Treatment and Cure of Epidermolysis Bullosa: Summary of the DEBRA International Research Symposium EB2015", JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 136, no. 2, 1 February 2016 (2016-02-01), NL, pages 352 - 358, XP055352164, ISSN: 0022-202X, DOI: 10.1016/j.jid.2015.10.050 * |
| MARIANGELA PUCCI ET AL: "Epigenetic control of skin differentiation genes by phytocannabinoids : Epigenesis of skin genes by phytocannabinoids", BRITISH JOURNAL OF PHARMACOLOGY, vol. 170, no. 3, 17 September 2013 (2013-09-17), UK, pages 581 - 591, XP055508939, ISSN: 0007-1188, DOI: 10.1111/bph.12309 * |
| See also references of WO2017190249A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CA3023049A1 (en) | 2017-11-09 |
| IL262702A (en) | 2018-12-31 |
| JP2019518075A (en) | 2019-06-27 |
| EP3452036A1 (en) | 2019-03-13 |
| SG11201809688RA (en) | 2018-11-29 |
| AU2017260706B2 (en) | 2023-05-11 |
| JP7342183B2 (en) | 2023-09-11 |
| CN109689045A (en) | 2019-04-26 |
| JP7054691B2 (en) | 2022-04-14 |
| AU2017260706A1 (en) | 2018-11-22 |
| IL262702B (en) | 2022-06-01 |
| WO2017190249A1 (en) | 2017-11-09 |
| JP2022084953A (en) | 2022-06-07 |
| US20190142788A1 (en) | 2019-05-16 |
| US12042479B2 (en) | 2024-07-23 |
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| STAA | Information on the status of an ep patent application or granted ep patent |
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| A4 | Supplementary search report drawn up and despatched |
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| RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 31/343 20060101ALI20191002BHEP Ipc: A61K 31/352 20060101AFI20191002BHEP Ipc: A61K 31/4172 20060101ALI20191002BHEP Ipc: A61K 31/473 20060101ALI20191002BHEP Ipc: A61P 17/00 20060101ALI20191002BHEP Ipc: A61K 31/415 20060101ALI20191002BHEP Ipc: A61K 31/397 20060101ALI20191002BHEP Ipc: A61K 31/05 20060101ALI20191002BHEP Ipc: A61K 31/404 20060101ALI20191002BHEP Ipc: A61K 31/4162 20060101ALI20191002BHEP Ipc: A61K 31/122 20060101ALI20191002BHEP Ipc: A61K 31/5383 20060101ALI20191002BHEP |
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| RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: INMED PHARMACEUTICALS INC. |
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