EP3305808A4 - Microorganisme produisant de l'o-acétyl-homosérine et procédé de production d'o-acétyl-homosérine l'utilisant - Google Patents

Microorganisme produisant de l'o-acétyl-homosérine et procédé de production d'o-acétyl-homosérine l'utilisant Download PDF

Info

Publication number: EP3305808A4
Authority: EP; European Patent Office
Prior art keywords: homoserine; acetyl; producing; same; microorganism
Prior art date: 2015-06-04
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

EP16803792.7A

Other languages

German (de)

English (en)

Other versions

EP3305808B1 (fr

EP3305808A1 (fr

Inventor

Jee Yeon BAE

Ji Hyun Shim

Hyun Ah Kim

Juhee Seo

Yong Uk Shin

Jae Hee Lee

Sang Kyoum Kim

So Young Kim

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

CJ CheilJedang Corp

Original Assignee

CJ CheilJedang Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2015-06-04

Filing date

2016-06-03

Publication date

2018-12-05

2016-06-03 Application filed by CJ CheilJedang Corp filed Critical CJ CheilJedang Corp

2016-06-03 Priority to PL16803792T priority Critical patent/PL3305808T3/pl

2018-04-11 Publication of EP3305808A1 publication Critical patent/EP3305808A1/fr

2018-12-05 Publication of EP3305808A4 publication Critical patent/EP3305808A4/fr

2022-01-12 Application granted granted Critical

2022-01-12 Publication of EP3305808B1 publication Critical patent/EP3305808B1/fr

Status Active legal-status Critical Current

2036-06-03 Anticipated expiration legal-status Critical

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/12—Methionine; Cysteine; Cystine
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
- C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
- C12Y102/01011—Aspartate-semialdehyde dehydrogenase (1.2.1.11)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y106/00—Oxidoreductases acting on NADH or NADPH (1.6)
- C12Y106/01—Oxidoreductases acting on NADH or NADPH (1.6) with NAD+ or NADP+ as acceptor (1.6.1)
- C12Y106/01001—NAD(P)+ transhydrogenase (B-specific) (1.6.1.1)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
- C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
- C12Y203/01031—Homoserine O-acetyltransferase (2.3.1.31)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
- C12Y207/01039—Homoserine kinase (2.7.1.39)

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
General Health & Medical Sciences (AREA)
General Engineering & Computer Science (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Biophysics (AREA)
Plant Pathology (AREA)
Physics & Mathematics (AREA)
Gastroenterology & Hepatology (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)

EP16803792.7A 2015-06-04 2016-06-03 Microorganisme produisant de l'o-acétyl-homosérine et procédé de production d'o-acétyl-homosérine l'utilisant Active EP3305808B1 (fr)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
PL16803792T PL3305808T3 (pl)	2015-06-04	2016-06-03	Mikroorganizm wytwarzający o-acetylohomoserynę i sposób wytwarzania o-acetylohomoseryny z jego zastosowaniem

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
KR20150079358		2015-06-04
PCT/KR2016/005951 WO2016195439A1 (fr)	2015-06-04	2016-06-03	Microorganisme produisant de l'o-acétyl-homosérine et procédé de production d'o-acétyl-homosérine l'utilisant

Publications (3)

Publication Number	Publication Date
EP3305808A1 EP3305808A1 (fr)	2018-04-11
EP3305808A4 true EP3305808A4 (fr)	2018-12-05
EP3305808B1 EP3305808B1 (fr)	2022-01-12

Family

ID=57440936

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP16803792.7A Active EP3305808B1 (fr)	2015-06-04	2016-06-03	Microorganisme produisant de l'o-acétyl-homosérine et procédé de production d'o-acétyl-homosérine l'utilisant

Country Status (14)

Country	Link
US (2)	US10400256B2 (fr)
EP (1)	EP3305808B1 (fr)
JP (1)	JP6543734B2 (fr)
KR (1)	KR101859276B1 (fr)
CN (1)	CN108026147B (fr)
AU (1)	AU2016271665B2 (fr)
BR (1)	BR112017026005A2 (fr)
ES (1)	ES2906229T3 (fr)
HU (1)	HUE057284T2 (fr)
MY (1)	MY174840A (fr)
PL (1)	PL3305808T3 (fr)
RU (1)	RU2706535C2 (fr)
SG (1)	SG11201709899QA (fr)
WO (1)	WO2016195439A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR101996769B1 (ko) *	2018-12-21	2019-10-01	씨제이제일제당 (주)	변이형 호모세린 디하이드로게나제 및 이를 이용한 호모세린 또는 호모세린 유래 l-아미노산의 생산 방법
KR102182497B1 (ko) *	2019-12-20	2020-11-24	씨제이제일제당 주식회사	내막 단백질의 변이체 및 이를 이용한 목적 산물 생산 방법
CN115728496B (zh) *	2022-11-11	2025-07-29	东南大学	碳点复合物作为探针和共反应物的免疫传感器及其应用
CN119082224B (zh) *	2024-09-26	2025-12-12	杭州精构生物科技有限责任公司	一种生产o-乙酰高丝氨酸的大肠埃希氏菌工程菌株的发酵方法

Citations (3)

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Publication number	Priority date	Publication date	Assignee	Title
WO2008013432A1 (fr) *	2006-07-28	2008-01-31	Cj Cheiljedang Corporation	Micro-organisme produisant un précurseur de l-méthionine et procédé de production de l-méthionine et d'acide organique à partir du précurseur de l-méthionine
EP2657250A2 (fr) *	2010-12-21	2013-10-30	CJ CheilJedang Corporation	Polypeptide de variant possédant une activité d'homosérine acétyltransférase et microorganisme l'exprimant
WO2014145334A1 (fr) *	2013-03-15	2014-09-18	Opx Biotechnologies, Inc.	Mutations d'acétyl-coa carboxylase

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RU2175351C2 (ru)	1998-12-30	2001-10-27	Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО "АГРИ")	Фрагмент днк из escherichia coli, определяющий повышенную продукцию l-аминокислот (варианты), и способ получения l-аминокислот
DE10305774A1 (de)	2003-02-06	2004-08-26	Consortium für elektrochemische Industrie GmbH	Verfahren zur fermentativen Herstellung von L-Methionin
BRPI0811838A2 (pt)	2007-05-22	2014-10-07	Basf Plant Science Gmbh	Método para a produção de uma célula de planta transgênica ou uma parte da mesma, célula de planta transgênica, uma planta ou uma parte da mesma, semente, molécula de ácido nucleico isolada, construto de ácido nucleico, vetor, célula hospedeira, processo para a produção de um polipeptídeo, polipeptídeo, anticorpo, tecido de planta, material de propagação, material colhido ou uma planta, processo para a identificação de um composto, método para produção de uma composição agrícola, composição, método para produção de uma planta transgênica, e, uso de uma molécula de ácido nucleico de codificação de srp
ES2624913T3 (es) *	2008-09-08	2017-07-18	Ajinomoto Co., Inc.	Microorganismo que produce un L-aminoácido y procedimiento para producir un L-aminoácido
JP5521347B2 (ja) *	2009-02-16	2014-06-11	味の素株式会社	Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造法
US8283152B2 (en) *	2009-08-28	2012-10-09	Cj Cheiljedang Corporation	Microorganism producing O-acetyl-homoserine and the method of producing O-acetyl-homoserine using the microorganism
AR083468A1 (es)	2010-10-25	2013-02-27	Metabolic Explorer Sa	Aumento de la disponibilidad de nadph para la produccion de metionina
KR101250651B1 (ko)	2010-12-21	2013-04-03	씨제이제일제당 (주)	신규 ｏ-아세틸호모세린 설피드릴라제 또는 변이체 및 이를 이용한 메치오닌 전환 방법

2016
- 2016-06-03 ES ES16803792T patent/ES2906229T3/es active Active
- 2016-06-03 HU HUE16803792A patent/HUE057284T2/hu unknown
- 2016-06-03 BR BR112017026005-0A patent/BR112017026005A2/pt unknown
- 2016-06-03 US US15/579,188 patent/US10400256B2/en active Active
- 2016-06-03 WO PCT/KR2016/005951 patent/WO2016195439A1/fr not_active Ceased
- 2016-06-03 RU RU2017144551A patent/RU2706535C2/ru active
- 2016-06-03 KR KR1020160069827A patent/KR101859276B1/ko active Active
- 2016-06-03 AU AU2016271665A patent/AU2016271665B2/en active Active
- 2016-06-03 MY MYPI2017704565A patent/MY174840A/en unknown
- 2016-06-03 CN CN201680043236.0A patent/CN108026147B/zh active Active
- 2016-06-03 PL PL16803792T patent/PL3305808T3/pl unknown
- 2016-06-03 SG SG11201709899QA patent/SG11201709899QA/en unknown
- 2016-06-03 JP JP2017562280A patent/JP6543734B2/ja active Active
- 2016-06-03 EP EP16803792.7A patent/EP3305808B1/fr active Active
2019
- 2019-07-17 US US16/514,777 patent/US10597686B2/en active Active

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2008013432A1 (fr) *	2006-07-28	2008-01-31	Cj Cheiljedang Corporation	Micro-organisme produisant un précurseur de l-méthionine et procédé de production de l-méthionine et d'acide organique à partir du précurseur de l-méthionine
EP2657250A2 (fr) *	2010-12-21	2013-10-30	CJ CheilJedang Corporation	Polypeptide de variant possédant une activité d'homosérine acétyltransférase et microorganisme l'exprimant
WO2014145334A1 (fr) *	2013-03-15	2014-09-18	Opx Biotechnologies, Inc.	Mutations d'acétyl-coa carboxylase

Non-Patent Citations (4)

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Title
DATABASE Geneseq [online] 9 July 2009 (2009-07-09), "Environmental stress related sequence, SEQ ID 8934.", XP002785583, retrieved from EBI accession no. GSN:AWF72241 Database accession no. AWF72241 *
DATABASE Protein [online] 31 January 2014 (2014-01-31), "leucine export protein LeuE [Providencia stuartii MRSN 2154]", XP002785582, retrieved from NCBI Database accession no. AFH92508 *
DATABASE UniProt [online] 3 September 2014 (2014-09-03), "SubName: Full=Leucine export protein LeuE {ECO:0000313\|EMBL:KDM91107.1};", XP002785581, retrieved from EBI accession no. UNIPROT:A0A066RTU4 Database accession no. A0A066RTU4 *
See also references of WO2016195439A1 *

Also Published As

Publication number	Publication date
KR101859276B1 (ko)	2018-05-18
HUE057284T2 (hu)	2022-04-28
MY174840A (en)	2020-05-18
CN108026147B (zh)	2021-10-01
SG11201709899QA (en)	2017-12-28
AU2016271665B2 (en)	2019-05-09
JP2018517411A (ja)	2018-07-05
EP3305808B1 (fr)	2022-01-12
CN108026147A (zh)	2018-05-11
AU2016271665A1 (en)	2018-01-04
US20190338322A1 (en)	2019-11-07
JP6543734B2 (ja)	2019-07-10
ES2906229T3 (es)	2022-04-13
RU2017144551A (ru)	2019-07-09
RU2706535C2 (ru)	2019-11-19
WO2016195439A1 (fr)	2016-12-08
BR112017026005A2 (pt)	2018-08-14
KR20160144017A (ko)	2016-12-15
US20180135086A1 (en)	2018-05-17
PL3305808T3 (pl)	2022-04-04
RU2017144551A3 (fr)	2019-07-17
EP3305808A1 (fr)	2018-04-11
US10400256B2 (en)	2019-09-03
US10597686B2 (en)	2020-03-24

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