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EP3304040A4 - SYSTEM AND APPARATUS FOR BLIND DECONVOLUTION OF FLOW CYTOMETER PARTICLE EMISSION - Google Patents

SYSTEM AND APPARATUS FOR BLIND DECONVOLUTION OF FLOW CYTOMETER PARTICLE EMISSION Download PDF

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Publication number
EP3304040A4
EP3304040A4 EP16799468.0A EP16799468A EP3304040A4 EP 3304040 A4 EP3304040 A4 EP 3304040A4 EP 16799468 A EP16799468 A EP 16799468A EP 3304040 A4 EP3304040 A4 EP 3304040A4
Authority
EP
European Patent Office
Prior art keywords
flow cytometer
particle emission
blind deconvolution
cytometer particle
deconvolution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP16799468.0A
Other languages
German (de)
French (fr)
Other versions
EP3304040A1 (en
EP3304040B1 (en
Inventor
Harvey Lee Kasdan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Accellix Ltd
Original Assignee
LEUKODX Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LEUKODX Ltd filed Critical LEUKODX Ltd
Publication of EP3304040A1 publication Critical patent/EP3304040A1/en
Publication of EP3304040A4 publication Critical patent/EP3304040A4/en
Application granted granted Critical
Publication of EP3304040B1 publication Critical patent/EP3304040B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429Signal processing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N2015/1006Investigating individual particles for cytology

Landscapes

  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
EP16799468.0A 2015-05-28 2016-05-23 System and apparatus for blind deconvolution of flow cytometer particle emission Active EP3304040B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562167524P 2015-05-28 2015-05-28
PCT/IL2016/000010 WO2016189522A1 (en) 2015-05-28 2016-05-23 System and apparatus for blind deconvolution of flow cytometer particle emission

Publications (3)

Publication Number Publication Date
EP3304040A1 EP3304040A1 (en) 2018-04-11
EP3304040A4 true EP3304040A4 (en) 2019-03-13
EP3304040B1 EP3304040B1 (en) 2023-04-19

Family

ID=57393937

Family Applications (1)

Application Number Title Priority Date Filing Date
EP16799468.0A Active EP3304040B1 (en) 2015-05-28 2016-05-23 System and apparatus for blind deconvolution of flow cytometer particle emission

Country Status (3)

Country Link
US (2) US10527538B2 (en)
EP (1) EP3304040B1 (en)
WO (1) WO2016189522A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016189522A1 (en) * 2015-05-28 2016-12-01 Leukodx, Ltd. System and apparatus for blind deconvolution of flow cytometer particle emission
US10883912B2 (en) * 2018-06-04 2021-01-05 Becton, Dickinson And Company Biexponential transformation for graphics display
CN114341926B (en) * 2019-08-09 2025-06-17 得克萨斯大学体系董事会 Methods for high performance electron microscopy
US20220404262A1 (en) * 2019-11-06 2022-12-22 Sony Group Corporation Optical measurement device and lens structure
CN116595291B (en) * 2023-07-18 2023-09-26 武汉怡特环保科技有限公司 Multi-exponential fitting method and device for fluorescence attenuation curve and computer equipment
CN120107664B (en) * 2025-02-14 2025-08-12 电子科技大学 Infrared target type identification method and device for emission position guided sampling matching

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5909278A (en) * 1996-07-29 1999-06-01 The Regents Of The University Of California Time-resolved fluorescence decay measurements for flowing particles
US7060992B1 (en) * 2003-03-10 2006-06-13 Tiax Llc System and method for bioaerosol discrimination by time-resolved fluorescence

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WO2002017219A1 (en) * 2000-08-25 2002-02-28 Amnis Corporation Measuring the velocity of small moving objects such as cells
DK2305172T3 (en) * 2003-03-28 2016-08-22 Inguran Llc DEVICE AND PROCEDURES TO PROVIDE SEXUAL ANIMAL SEED
WO2004102165A1 (en) 2003-05-07 2004-11-25 Novasite Pharmaceuticals, Inc. Multiplexed multitarget screening method
US7842512B2 (en) 2004-03-26 2010-11-30 Purdue Research Foundation Dyed microspheres for characterization of photochemical reactor behavior
WO2006127967A2 (en) 2005-05-25 2006-11-30 Massachusetts Institute Of Technology Multifocal scanning microscopy systems and methods
US8779390B2 (en) 2008-05-13 2014-07-15 Macquarie University Auto-synchronous fluorescence detection method and apparatus
FR2939199B1 (en) * 2008-12-02 2011-02-11 C2 Diagnostics METHOD AND DEVICE FOR FLOW CYTOMETRY WITHOUT SAGING FLUID
CN105572019B (en) 2010-04-15 2018-12-21 洛伊克德克斯有限公司 For quickly determining the equipment, system and method for medical conditions
WO2013138159A1 (en) * 2012-03-15 2013-09-19 Amgen Inc. Methods of determining exposure to uv light
JP6298474B2 (en) 2012-12-17 2018-03-20 レウコドゥックス,リミテッド Systems and methods for detecting biological conditions
ES2880609T3 (en) 2013-03-14 2021-11-25 Abbott Lab Methods for Detecting Matching Sample Events
WO2016189522A1 (en) * 2015-05-28 2016-12-01 Leukodx, Ltd. System and apparatus for blind deconvolution of flow cytometer particle emission

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5909278A (en) * 1996-07-29 1999-06-01 The Regents Of The University Of California Time-resolved fluorescence decay measurements for flowing particles
US7060992B1 (en) * 2003-03-10 2006-06-13 Tiax Llc System and method for bioaerosol discrimination by time-resolved fluorescence

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2016189522A1 *

Also Published As

Publication number Publication date
EP3304040A1 (en) 2018-04-11
US10527538B2 (en) 2020-01-07
US20180306698A1 (en) 2018-10-25
US10809179B2 (en) 2020-10-20
US20200080928A1 (en) 2020-03-12
WO2016189522A1 (en) 2016-12-01
EP3304040B1 (en) 2023-04-19

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