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EP3209331C0 - Solution ophtalmique - Google Patents

Solution ophtalmique

Info

Publication number
EP3209331C0
EP3209331C0 EP15791036.5A EP15791036A EP3209331C0 EP 3209331 C0 EP3209331 C0 EP 3209331C0 EP 15791036 A EP15791036 A EP 15791036A EP 3209331 C0 EP3209331 C0 EP 3209331C0
Authority
EP
European Patent Office
Prior art keywords
eye solution
eye
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP15791036.5A
Other languages
German (de)
English (en)
Other versions
EP3209331A1 (fr
EP3209331B1 (fr
Inventor
Mandar V Shah
Deepak Bahri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sentiss Pharma Pvt Ltd
Original Assignee
Sentiss Pharma Pvt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sentiss Pharma Pvt Ltd filed Critical Sentiss Pharma Pvt Ltd
Publication of EP3209331A1 publication Critical patent/EP3209331A1/fr
Application granted granted Critical
Publication of EP3209331C0 publication Critical patent/EP3209331C0/fr
Publication of EP3209331B1 publication Critical patent/EP3209331B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP15791036.5A 2014-10-20 2015-10-16 Solution ophtalmique Active EP3209331B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2985DE2014 2014-10-20
PCT/IB2015/057963 WO2016063184A1 (fr) 2014-10-20 2015-10-16 Solution ophtalmique

Publications (3)

Publication Number Publication Date
EP3209331A1 EP3209331A1 (fr) 2017-08-30
EP3209331C0 true EP3209331C0 (fr) 2023-07-12
EP3209331B1 EP3209331B1 (fr) 2023-07-12

Family

ID=54477035

Family Applications (1)

Application Number Title Priority Date Filing Date
EP15791036.5A Active EP3209331B1 (fr) 2014-10-20 2015-10-16 Solution ophtalmique

Country Status (7)

Country Link
US (1) US11285163B2 (fr)
EP (1) EP3209331B1 (fr)
JP (1) JP6704400B2 (fr)
EA (1) EA034839B1 (fr)
ES (1) ES2954412T3 (fr)
UA (1) UA124698C2 (fr)
WO (1) WO2016063184A1 (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA124698C2 (uk) 2014-10-20 2021-11-03 Сентіс Фарма Прайвет Лімітед Офтальмологічний розчин
WO2017055454A1 (fr) 2015-09-30 2017-04-06 Novaliq Gmbh Composés semi-fluorés et leurs compositions
US20190209465A1 (en) * 2016-07-01 2019-07-11 Pharmathen S.A. Process for preparing pharmaceutical ophthalmic compositions of brinzolamide
JP6931493B2 (ja) * 2017-06-22 2021-09-08 ヨンスン ファイン ケミカル カンパニー,リミテッド 緑内障治療用点眼組成物
CN110269867B (zh) * 2018-03-14 2022-06-21 必康生技(香港)有限公司 用于生物流体净化的组合物
JP7496778B2 (ja) * 2018-03-28 2024-06-07 ノバリック ゲーエムベーハー チモロールを含む医薬組成物
JP2021521240A (ja) * 2018-04-25 2021-08-26 シルパ メディケア リミテッドShilpa Medicare Limited ブリンゾラミドの眼科用組成物
WO2019206956A1 (fr) 2018-04-27 2019-10-31 Novaliq Gmbh Compositions ophtalmiques comprenant du tafluprost pour le traitement du glaucome
GR1009616B (el) * 2018-07-20 2019-10-11 Φαρματεν Α.Β.Ε.Ε. Οφθαλμικο φαρμακευτικο σκευασμα που περιεχει βρινζολαμιδη και τιμολολη και μεθοδος παρασκευης αυτου
CA3115664A1 (fr) * 2018-08-29 2020-03-05 Ocugen, Inc. Compositions ophtalmiques et methodes d'utilisation
MY206642A (en) 2018-10-12 2024-12-30 Novaliq Gmbh Ophthalmic composition for treatment of dry eye disease
CN110193084A (zh) * 2019-07-02 2019-09-03 付纪军 一种含聚乙烯己内酰胺-聚乙酸乙烯酯-聚乙二醇接枝共聚物的药物制剂及其制备方法
AU2020340561A1 (en) 2019-09-06 2022-03-31 Novaliq Gmbh Ophthalmic composition for the treatment of uveitis
IL271763A (en) * 2019-12-30 2021-06-30 Michael Belkin Preparations, kits and methods for the treatment of glaucoma
WO2021240376A2 (fr) 2020-05-27 2021-12-02 Lupin Limited Compositions de nanoémulsion ophtalmique
US11850249B2 (en) * 2020-10-05 2023-12-26 Somerset Therapeutics, Llc Methods of efficiently reducing intraocular pressure
WO2022081297A1 (fr) * 2020-10-12 2022-04-21 The Regents Of The University Of Colorado, A Body Corporate Compositions et méthodes pour abaisser la pression intracrânienne par administration intranasale d'un agent
JP6855026B1 (ja) * 2020-11-09 2021-04-07 東亜薬品株式会社 タフルプロスト点眼液
WO2024241345A1 (fr) * 2023-05-22 2024-11-28 Sentiss Pharma Private Limited Composition de suspension ophtalmique de brinzolamide et de latanoprost
WO2025230326A1 (fr) * 2024-04-30 2025-11-06 주식회사태준제약 Composition ophtalmique comprenant de la pilocarpine

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4599353A (en) 1982-05-03 1986-07-08 The Trustees Of Columbia University In The City Of New York Use of eicosanoids and their derivatives for treatment of ocular hypertension and glaucoma
ATE108330T1 (de) 1987-09-18 1994-07-15 R Tech Ueno Ltd Hypotensive okulare mittel.
ATE420857T1 (de) 1988-09-06 2009-01-15 Pfizer Health Ab Prostaglandin-derivate zur behandlung von glaukom und ocularer hypertension
US5153192A (en) 1990-04-09 1992-10-06 Alcon Laboratories, Inc. Thiophene sulfonamides useful as carbonic anhydrase inhibitors
US5378703A (en) * 1990-04-09 1995-01-03 Alcon Laboratories, Inc. Sulfonamides useful as carbonic anhydrase inhibitors
US5352708A (en) 1992-09-21 1994-10-04 Allergan, Inc. Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
US5510383A (en) 1993-08-03 1996-04-23 Alcon Laboratories, Inc. Use of cloprostenol, fluprostenol and their salts and esters to treat glaucoma and ocular hypertension
FR2754712B1 (fr) * 1996-10-17 1999-09-03 Merck Sharp Dohme Chibret Lab Compositions ophtalmiques
US6071904A (en) 1996-12-11 2000-06-06 Alcon Laboratories, Inc. Process for manufacturing ophthalmic suspensions
MX2009000885A (es) 2006-07-25 2009-02-05 Osmotica Corp Soluciones oftalmicas.
WO2008027340A2 (fr) * 2006-08-30 2008-03-06 Merck & Co., Inc. Formulations ophtalmiques locales
TWI544927B (zh) 2008-03-17 2016-08-11 愛爾康研究有限公司 具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物
JP2010037327A (ja) * 2008-07-07 2010-02-18 Wakamoto Pharmaceut Co Ltd ブリンゾラミド水性組成物
JP5558582B2 (ja) 2009-12-03 2014-07-23 ルピン・リミテッド 眼科用医薬組成物の調製方法
CA2805425C (fr) * 2010-07-15 2019-07-23 Corinthian Ophthalmic, Inc. Administration de medicament ophtalmique
JP2014520895A (ja) * 2011-07-20 2014-08-25 アラーガン インコーポレイテッド ビマトプロストおよびブリモニジンの固定用量の組み合わせ
US20130035338A1 (en) * 2011-08-05 2013-02-07 Gordon Tang Eyelid treatment
RU2014129268A (ru) * 2011-12-16 2016-02-10 Аллерган, Инк. Офтальмологические составы, которые содержат привитые сополимеры поливинилкапролактам-поливинилацетат-полиэтиленгликоля
GR1007906B (el) * 2012-03-22 2013-05-30 Φαρματεν Αβεε, Οφθαλμικο φαρμακευτικο σκευασμα περιεχον ενα αναστολεα καρβονικης ανυδρασης και μεθοδος για την παρασκευη αυτου
EP3096740B1 (fr) * 2014-01-24 2020-09-30 Sentiss Pharma Private Limited Composition pharmaceutique comprenant du brinzolamide
UA124698C2 (uk) 2014-10-20 2021-11-03 Сентіс Фарма Прайвет Лімітед Офтальмологічний розчин

Also Published As

Publication number Publication date
EP3209331A1 (fr) 2017-08-30
EA034839B1 (ru) 2020-03-26
ES2954412T3 (es) 2023-11-22
US20170304316A1 (en) 2017-10-26
JP6704400B2 (ja) 2020-06-03
EA201790889A1 (ru) 2017-08-31
WO2016063184A1 (fr) 2016-04-28
US11285163B2 (en) 2022-03-29
EP3209331B1 (fr) 2023-07-12
JP2017531045A (ja) 2017-10-19
UA124698C2 (uk) 2021-11-03

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