[go: up one dir, main page]

EP3259342A4 - Method and apparatus for dynamically culturing a biological sample - Google Patents

Method and apparatus for dynamically culturing a biological sample Download PDF

Info

Publication number
EP3259342A4
EP3259342A4 EP16751802.6A EP16751802A EP3259342A4 EP 3259342 A4 EP3259342 A4 EP 3259342A4 EP 16751802 A EP16751802 A EP 16751802A EP 3259342 A4 EP3259342 A4 EP 3259342A4
Authority
EP
European Patent Office
Prior art keywords
biological sample
dynamically culturing
culturing
dynamically
biological
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP16751802.6A
Other languages
German (de)
French (fr)
Other versions
EP3259342A1 (en
Inventor
Eduardo Vom
Simon Jonathon Spence
Samuel Ross Garland Lanyon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genea IP Holdings Pty Ltd
Original Assignee
Genea IP Holdings Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2015900536A external-priority patent/AU2015900536A0/en
Application filed by Genea IP Holdings Pty Ltd filed Critical Genea IP Holdings Pty Ltd
Publication of EP3259342A1 publication Critical patent/EP3259342A1/en
Publication of EP3259342A4 publication Critical patent/EP3259342A4/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q3/00—Condition responsive control processes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/06—Bioreactors or fermenters specially adapted for specific uses for in vitro fertilization
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/32—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of substances in solution
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Computer Hardware Design (AREA)
  • Cell Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP16751802.6A 2015-02-17 2016-02-17 Method and apparatus for dynamically culturing a biological sample Pending EP3259342A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2015900536A AU2015900536A0 (en) 2015-02-17 Method and Apparatus for Dynamically Culturing a Biological Sample
PCT/AU2016/000044 WO2016131079A1 (en) 2015-02-17 2016-02-17 Method and apparatus for dynamically culturing a biological sample

Publications (2)

Publication Number Publication Date
EP3259342A1 EP3259342A1 (en) 2017-12-27
EP3259342A4 true EP3259342A4 (en) 2018-10-17

Family

ID=56691894

Family Applications (1)

Application Number Title Priority Date Filing Date
EP16751802.6A Pending EP3259342A4 (en) 2015-02-17 2016-02-17 Method and apparatus for dynamically culturing a biological sample

Country Status (5)

Country Link
US (1) US20180023149A1 (en)
EP (1) EP3259342A4 (en)
JP (4) JP2018508234A (en)
HK (1) HK1247952A1 (en)
WO (1) WO2016131079A1 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3619292A1 (en) * 2017-05-04 2020-03-11 Doody, M.D., Kevin J. In vitro fertilization fertilized egg incubation system
CN118767728A (en) 2018-01-17 2024-10-15 生命技术公司 Fluid mixing system including a spiral mixing assembly with an impeller attachment and method of use
CN112384605A (en) * 2018-05-30 2021-02-19 生命技术公司 Control system and method for fluid mixing device
EP3924459A1 (en) * 2019-03-11 2021-12-22 Forever Labs, Inc. Dynamic incubator system and method
CN110684660A (en) * 2019-11-01 2020-01-14 力盟生命科技(深圳)有限公司 Micro-vibration culture device for embryos
JP2023523427A (en) * 2020-04-24 2023-06-05 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア Digital fluid teleportation, advanced biological virtualization, and large-scale integration of biological functional chips and biomimetic models
EP4227724A1 (en) * 2022-02-14 2023-08-16 Leica Microsystems CMS GmbH Microscope parameter controller, microscope arrangement and method for controlling microscope parameters
GB2615819A (en) * 2022-02-22 2023-08-23 Oribiotech Ltd A bioreactor system
JP7735544B2 (en) * 2022-03-30 2025-09-08 本田技研工業株式会社 Cultivation method and culture device
CN119998435A (en) * 2022-11-07 2025-05-13 Esco医疗技术有限公司 Modular incubator system for monitoring morphological development of viable biomaterials during incubation
AU2023378830A1 (en) * 2022-11-07 2024-12-05 Esco Medical Technologies, Uab A valve system for a modular incubator system
AU2023378833A1 (en) * 2022-11-07 2024-12-05 Esco Medical Technologies, Uab A modular incubator system providing improved illumination for image capture of an incubated biological material
WO2024099598A1 (en) * 2022-11-07 2024-05-16 Esco Medical Technologies, Uab A modular incubator system
JP2025536597A (en) * 2022-11-07 2025-11-07 エスコ メディカル テクノロジーズ、ユーエイビー Docking station for a modular incubator system with an improved gas distribution system
HUP2300117A1 (en) * 2023-04-11 2024-10-28 Pecsi Tudomanyegyetem System and process for in vitro monitoring of embryos
CN118909760A (en) * 2024-08-28 2024-11-08 启东芳景生物科技有限公司 Automatic alarm device and method for biological cell detection

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030092178A1 (en) * 2001-11-15 2003-05-15 Biospherix, Ltd. Cell culture incubator with dynamic oxygen control
WO2009118015A2 (en) * 2008-08-01 2009-10-01 Smart Biosystems Aps A sample port of a cell culture system
WO2011090792A1 (en) * 2010-01-20 2011-07-28 Millipore Corporation Cell image capturing and remote monitoring systems
WO2013004644A1 (en) * 2011-07-01 2013-01-10 Universiteit Twente Microfluidic device with integrated sensors for cultivation of cells

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009039433A1 (en) * 2007-09-20 2009-03-26 Incept Biosystems Inc. Analytical microfluidic culture system
NZ598293A (en) * 2009-08-22 2014-06-27 Univ Leland Stanford Junior Imaging and evaluating embryos, oocytes, and stem cells
WO2012047678A2 (en) * 2010-09-27 2012-04-12 Auxogyn, Inc. Apparatus, method, and system for the automated imaging and evaluation of embryos, oocytes, and stem cells
US20140017717A1 (en) * 2012-05-31 2014-01-16 Auxogyn, Inc. In vitro embryo blastocyst prediction methods
EP2906680A1 (en) * 2012-10-15 2015-08-19 Unisense Fertilitech A/S Embryo incubator incorporating gas control
JP6360840B2 (en) * 2013-03-01 2018-07-18 ジェネア アイピー ホールディングス ピーティーワイ リミテッド Apparatus, method and system for monitoring culture sample development
EP3011047B1 (en) * 2013-06-18 2018-08-01 INSERM - Institut National de la Santé et de la Recherche Médicale Methods for determining the quality of an embryo

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030092178A1 (en) * 2001-11-15 2003-05-15 Biospherix, Ltd. Cell culture incubator with dynamic oxygen control
WO2009118015A2 (en) * 2008-08-01 2009-10-01 Smart Biosystems Aps A sample port of a cell culture system
WO2011090792A1 (en) * 2010-01-20 2011-07-28 Millipore Corporation Cell image capturing and remote monitoring systems
WO2013004644A1 (en) * 2011-07-01 2013-01-10 Universiteit Twente Microfluidic device with integrated sensors for cultivation of cells

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
AISLING AHLSTRÖM ET AL: "Cross-validation and predictive value of near-infrared spectroscopy algorithms for day-5 blastocyst transfer", REPRODUCTIVE BIOMEDICINE ONLINE, ELSEVIER, AMSTERDAM, NL, vol. 22, no. 5, 18 January 2011 (2011-01-18), pages 477 - 484, XP028349496, ISSN: 1472-6483, [retrieved on 20110124], DOI: 10.1016/J.RBMO.2011.01.009 *
See also references of WO2016131079A1 *
SELI EMRE ET AL: "Noninvasive metabolomic profiling of embryo culture media using Raman and near-infrared spectroscopy correlates with reproductive potential of embryos in women undergoing in vitro fertilization", FERTILITY AND STERILITY, ELSEVIER SCIENCE INC, NEW YORK, NY, USA, vol. 88, no. 5, 17 October 2007 (2007-10-17), pages 1350 - 1357, XP029113793, ISSN: 0015-0282, DOI: 10.1016/J.FERTNSTERT.2007.07.1390 *

Also Published As

Publication number Publication date
JP2021072814A (en) 2021-05-13
JP2024028759A (en) 2024-03-05
HK1247952A1 (en) 2018-10-05
EP3259342A1 (en) 2017-12-27
JP2018508234A (en) 2018-03-29
WO2016131079A1 (en) 2016-08-25
US20180023149A1 (en) 2018-01-25
JP2022188054A (en) 2022-12-20

Similar Documents

Publication Publication Date Title
EP3259342A4 (en) Method and apparatus for dynamically culturing a biological sample
EP3149464A4 (en) System and method for electronic biological sample analysis
GB201616174D0 (en) Method and apparatus for analysing a biological sample
GB2543728B (en) Medical kit and method for processing a biological sample
EP3279310A4 (en) Cell culture apparatus and cell culture method
EP3189129A4 (en) Devices and methods for dissociating a biological tissue sample
EP3097211A4 (en) Method and system for microbiome analysis
EP3173786A4 (en) Analysis method for diluted biological sample component
EP3201627A4 (en) Device and method for chemical analysis
EP3249040A4 (en) Cell culture apparatus and cell culture method
EP3279655A4 (en) Method of preparing sample for analysis and analysis method
EP3116664A4 (en) Method and apparatus for sorting
EP3127480A4 (en) Biological measurement apparatus and biological measurement method
EP3313976A4 (en) Tissue culture apparatus and method
EP3196292A4 (en) Cell culture apparatus and method
EP3130220A4 (en) Hydroponic culturing apparatus and hydroponic culturing method
EP3163306A4 (en) Substrate for sample analysis, and sample analysis apparatus
IL269847A (en) Apparatus and method for picking biological sample
EP3201436A4 (en) Apparatus and method for providing a fluid sample in a well
EP3147661A4 (en) Method for pretreatment and method for analysis of lenalidomide in biological sample
EP3649470A4 (en) Methods and apparatus for sample analysis using lateral flow
EP3248006A4 (en) Method for preparing a biological sample for use in an immunolabeling process
EP3144681A4 (en) Sample analyzing apparatus
GB201502447D0 (en) Method and apparatus for sample analysis
IL268371A (en) Method and system for processing a biological sample

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20170822

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1247952

Country of ref document: HK

A4 Supplementary search report drawn up and despatched

Effective date: 20180918

RIC1 Information provided on ipc code assigned before grant

Ipc: C12M 3/00 20060101AFI20180912BHEP

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS

17Q First examination report despatched

Effective date: 20230127

REG Reference to a national code

Ref country code: HK

Ref legal event code: WD

Ref document number: 1247952

Country of ref document: HK