EP3244888A4 - Compositions and methods for inhibiting fungal infections - Google Patents

Compositions and methods for inhibiting fungal infections Download PDF

Info

Publication number: EP3244888A4
Authority: EP; European Patent Office
Prior art keywords: compositions; methods; fungal infections; inhibiting fungal; inhibiting
Prior art date: 2015-01-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP16737641.7A

Other languages

German (de)

French (fr)

Other versions

EP3244888A1 (en

Inventor

Chad RAPPLEYE

Alexander ZUKIWSKI

Stefan PRONIUK

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Ohio State Innovation Foundation

Original Assignee

Ohio State Innovation Foundation

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2015-01-12

Filing date

2016-01-07

Publication date

2018-12-05

2016-01-07 Application filed by Ohio State Innovation Foundation filed Critical Ohio State Innovation Foundation

2017-11-22 Publication of EP3244888A1 publication Critical patent/EP3244888A1/en

2018-12-05 Publication of EP3244888A4 publication Critical patent/EP3244888A4/en

Status Withdrawn legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)

EP16737641.7A 2015-01-12 2016-01-07 Compositions and methods for inhibiting fungal infections Withdrawn EP3244888A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US201562102436P	2015-01-12	2015-01-12
US201562143777P	2015-04-06	2015-04-06
PCT/US2016/012514 WO2016114976A1 (en)	2015-01-12	2016-01-07	Compositions and methods for inhibiting fungal infections

Publications (2)

Publication Number	Publication Date
EP3244888A1 EP3244888A1 (en)	2017-11-22
EP3244888A4 true EP3244888A4 (en)	2018-12-05

Family

ID=56366735

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP16737641.7A Withdrawn EP3244888A4 (en)	2015-01-12	2016-01-07	Compositions and methods for inhibiting fungal infections

Country Status (10)

Country	Link
US (1)	US20160199351A1 (en)
EP (1)	EP3244888A4 (en)
JP (1)	JP2018502128A (en)
KR (1)	KR20170102013A (en)
CN (1)	CN107249584A (en)
AU (1)	AU2016207029A1 (en)
CA (1)	CA2973698A1 (en)
MX (1)	MX2017009119A (en)
RU (1)	RU2017128615A (en)
WO (1)	WO2016114976A1 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US9029342B2 (en)	2012-09-17	2015-05-12	Board Of Regents Of The University Of Texas System	Compositions of matter that reduce pain, shock, and inflammation by blocking linoleic acid metabolites and uses thereof
US10070649B2 (en)	2013-01-30	2018-09-11	Agrofresh Inc.	Volatile applications against pathogens
US11039617B2 (en)	2013-01-30	2021-06-22	Agrofresh Inc.	Large scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness
US9744156B2 (en) *	2015-08-17	2017-08-29	Arno Therapeutics, Inc.	Methods and compositions for enhanced transungual delivery of AR-12
EP3426029B1 (en)	2016-03-07	2023-08-30	AgroFresh Inc.	Synergistic methods of using benzoxaborole compounds and preservative gases as an antimicrobial for crops
TW201804994A (en) *	2016-08-01	2018-02-16	中央研究院	Antifungal agents
WO2018144841A1 (en) *	2017-02-03	2018-08-09	Board Of Regents, The University Of Texas System	Topical voriconazole for the treatment of pain
US20220354783A1 (en) *	2018-08-01	2022-11-10	Edix-O Sarl	Injectable prolonged-action compositions for use in the treatment of nail disease and/or for promoting nail growth
CN109966473B (en) *	2019-05-14	2022-12-09	南京医科大学	A kind of antifungal product and application thereof of reduced glutamic acid combined with ascorbic acid and/or caspofungin
US12195755B2 (en)	2019-05-20	2025-01-14	Brown University	Placental lipid bilayer for cell-free molecular interaction studies
US11273124B2 (en) *	2019-05-23	2022-03-15	Brown University	Antifungal nanoparticles for targeted treatment of fungal infections
WO2021054533A2 (en) *	2019-09-17	2021-03-25	주식회사 바이오빌리프	Stabilized eficonazole-containing pharmaceutical composition comprising sorbic acid as acid
KR20210032662A (en) *	2019-09-17	2021-03-25	주식회사 바이오빌리프	Stabilized efinaconazole-containing pharmaceutical compositions comprising a chelating agent
CN112322695A (en) *	2020-11-03	2021-02-05	上海市肺科医院	An experimental method for the in vitro antibacterial activity of AR-12 against MABC
JP2023057423A (en) *	2021-10-11	2023-04-21	国立大学法人熊本大学	Agent for treating mucormycosis
CN118063384B (en) *	2024-02-07	2025-01-10	四川农业大学	Aromatic ring substituted pyrazole derivative and application thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE60108873D1 (en) *	2000-06-02	2005-03-17	Yu Liu	NON-ANTIBACTERIAL TETRAZYKLINE AS ANTI-MUSHROOM MEDICAMENTS
US20060079566A1 (en) *	2003-10-03	2006-04-13	Ching-Shih Chen	PDK-1/Akt signaling inhibitors
WO2006081327A2 (en) *	2005-01-25	2006-08-03	University Of Vermont And State Agricultural College	Small molecules that reduce fungal growth
US8039502B2 (en) *	2007-07-24	2011-10-18	The Ohio State University Research Foundation	Anti-infective agents against intracellular pathogens
AU2009240389A1 (en) *	2008-04-25	2009-10-29	Nanobio Corporation	Nanoemulsions for treating fungal, yeast and mold infections
CN102338100A (en) *	2010-07-19	2012-02-01	鸿富锦精密工业（深圳）有限公司	Fan device
AU2011201932A1 (en) *	2010-11-17	2012-05-31	University Of Rochester	Treatment or prevention of fungal infections with PDK1 inhibitors
US20120027618A1 (en) *	2011-08-16	2012-02-02	General Electric Company	Angled blade root

2016
- 2016-01-07 WO PCT/US2016/012514 patent/WO2016114976A1/en not_active Ceased
- 2016-01-07 MX MX2017009119A patent/MX2017009119A/en unknown
- 2016-01-07 AU AU2016207029A patent/AU2016207029A1/en not_active Abandoned
- 2016-01-07 RU RU2017128615A patent/RU2017128615A/en unknown
- 2016-01-07 CA CA2973698A patent/CA2973698A1/en not_active Abandoned
- 2016-01-07 US US14/990,594 patent/US20160199351A1/en not_active Abandoned
- 2016-01-07 KR KR1020177022510A patent/KR20170102013A/en not_active Withdrawn
- 2016-01-07 CN CN201680010418.8A patent/CN107249584A/en active Pending
- 2016-01-07 JP JP2017536946A patent/JP2018502128A/en active Pending
- 2016-01-07 EP EP16737641.7A patent/EP3244888A4/en not_active Withdrawn

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
L. J. WHEAT ET AL: "Clinical Practice Guidelines for the Management of Patients with Histoplasmosis: 2007 Update by the Infectious Diseases Society of America", CLINICAL INFECTIOUS DISEASES, vol. 45, no. 7, 1 October 2007 (2007-10-01), US, pages 807 - 825, XP055309323, ISSN: 1058-4838, DOI: 10.1086/521259 *
See also references of WO2016114976A1 *

Also Published As

Publication number	Publication date
MX2017009119A (en)	2018-03-16
US20160199351A1 (en)	2016-07-14
JP2018502128A (en)	2018-01-25
RU2017128615A (en)	2019-02-14
CN107249584A (en)	2017-10-13
EP3244888A1 (en)	2017-11-22
WO2016114976A1 (en)	2016-07-21
AU2016207029A1 (en)	2017-08-10
CA2973698A1 (en)	2016-07-21
KR20170102013A (en)	2017-09-06

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Legal Events

Date	Code	Title	Description
2017-07-28	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE
2017-10-20	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2017-10-20	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE
2017-11-22	17P	Request for examination filed	Effective date: 20170728
2017-11-22	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
2017-11-22	AX	Request for extension of the european patent	Extension state: BA ME
2018-04-18	DAV	Request for validation of the european patent (deleted)
2018-04-18	DAX	Request for extension of the european patent (deleted)
2018-05-09	RAP1	Party data changed (applicant data changed or rights of an application transferred)	Owner name: OHIO STATE INNOVATION FOUNDATION
2018-08-29	RIC1	Information provided on ipc code assigned before grant	Ipc: A61K 31/415 20060101AFI20180720BHEP Ipc: A61K 31/4196 20060101ALI20180720BHEP Ipc: A61P 31/10 20060101ALI20180720BHEP Ipc: A61K 45/06 20060101ALI20180720BHEP
2018-12-05	A4	Supplementary search report drawn up and despatched	Effective date: 20181030
2018-12-05	RIC1	Information provided on ipc code assigned before grant	Ipc: A61P 31/10 20060101ALI20181024BHEP Ipc: A61K 45/06 20060101ALI20181024BHEP Ipc: A61K 31/4196 20060101ALI20181024BHEP Ipc: A61K 31/415 20060101AFI20181024BHEP
2019-10-18	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2019-11-20	18D	Application deemed to be withdrawn	Effective date: 20190528