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EP2991624A4 - Formulation orale comprenant un extrait de rhizome de coptide présentant un goût amer masqué - Google Patents

Formulation orale comprenant un extrait de rhizome de coptide présentant un goût amer masqué

Info

Publication number
EP2991624A4
EP2991624A4 EP14791495.6A EP14791495A EP2991624A4 EP 2991624 A4 EP2991624 A4 EP 2991624A4 EP 14791495 A EP14791495 A EP 14791495A EP 2991624 A4 EP2991624 A4 EP 2991624A4
Authority
EP
European Patent Office
Prior art keywords
copytaus
bittered
oral formulation
rhizome extract
taste
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14791495.6A
Other languages
German (de)
English (en)
Other versions
EP2991624A1 (fr
Inventor
Youn Woong Choi
Byung Gu Min
Dea Chul Ha
Sang Min Cho
Hee Yong Song
Hee Chan Park
Ji Hyun Ahn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Korea United Pharm Inc
Original Assignee
Korea United Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Korea United Pharm Inc filed Critical Korea United Pharm Inc
Publication of EP2991624A1 publication Critical patent/EP2991624A1/fr
Publication of EP2991624A4 publication Critical patent/EP2991624A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP14791495.6A 2013-04-29 2014-04-29 Formulation orale comprenant un extrait de rhizome de coptide présentant un goût amer masqué Withdrawn EP2991624A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020130047566A KR101580119B1 (ko) 2013-04-29 2013-04-29 쓴맛이 차폐된 황련 추출물을 포함하는 경구투여용 제제
PCT/KR2014/003797 WO2014178617A1 (fr) 2013-04-29 2014-04-29 Formulation orale comprenant un extrait de rhizome de coptide présentant un goût amer masqué

Publications (2)

Publication Number Publication Date
EP2991624A1 EP2991624A1 (fr) 2016-03-09
EP2991624A4 true EP2991624A4 (fr) 2016-12-07

Family

ID=51843675

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14791495.6A Withdrawn EP2991624A4 (fr) 2013-04-29 2014-04-29 Formulation orale comprenant un extrait de rhizome de coptide présentant un goût amer masqué

Country Status (9)

Country Link
EP (1) EP2991624A4 (fr)
KR (1) KR101580119B1 (fr)
CN (1) CN105188669A (fr)
BR (1) BR112015026635A2 (fr)
HK (1) HK1212912A1 (fr)
MX (1) MX2015014623A (fr)
PH (1) PH12015502316A1 (fr)
RU (1) RU2667638C2 (fr)
WO (1) WO2014178617A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2937077B1 (fr) * 2014-04-24 2021-10-06 Montero Gida Sanayi Ve Ticaret A.S. Formulations orales liquides comprenant des extraits d'herbes
KR102528183B1 (ko) * 2021-01-27 2023-05-03 충북대학교 산학협력단 중머리풀 추출물과 이온교환수지를 포함하는 습식과립 제제 및 이의 제조방법

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009151300A2 (fr) * 2008-06-13 2009-12-17 Ahn-Gook Pharmaceutical Co., Ltd. Extrait de coptidis rhizoma et nouvelle utilisation de celui-ci dans le traitement d'une maladie respiratoire
CN101716220A (zh) * 2009-11-20 2010-06-02 杭州平和安康医药科技有限公司 掩蔽生物碱中药药物
CN101982200A (zh) * 2010-10-28 2011-03-02 中国中医科学院广安门医院 黄连总生物碱树脂复合物及其缓释制剂与它们的制备方法
CN102813928A (zh) * 2011-06-09 2012-12-12 上海张江中药现代制剂技术工程研究中心 一种改善小檗碱、盐酸小檗碱及相关复方制剂苦味的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4780429B2 (ja) * 2000-04-07 2011-09-28 大正製薬株式会社 ミノキシジル含有製剤
JP2011148776A (ja) * 2009-12-22 2011-08-04 Taisho Pharmaceutical Co Ltd 液剤組成物
CN102335400A (zh) * 2010-07-16 2012-02-01 冯相建 一种治疗冻疮的药膏
CN110198220A (zh) 2018-02-26 2019-09-03 中国移动通信有限公司研究院 一种vnf的扩缩容方法、装置及设备

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009151300A2 (fr) * 2008-06-13 2009-12-17 Ahn-Gook Pharmaceutical Co., Ltd. Extrait de coptidis rhizoma et nouvelle utilisation de celui-ci dans le traitement d'une maladie respiratoire
CN101716220A (zh) * 2009-11-20 2010-06-02 杭州平和安康医药科技有限公司 掩蔽生物碱中药药物
CN101982200A (zh) * 2010-10-28 2011-03-02 中国中医科学院广安门医院 黄连总生物碱树脂复合物及其缓释制剂与它们的制备方法
CN102813928A (zh) * 2011-06-09 2012-12-12 上海张江中药现代制剂技术工程研究中心 一种改善小檗碱、盐酸小檗碱及相关复方制剂苦味的方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
See also references of WO2014178617A1 *
TIMMER A TIMMER ET AL: "Pelargonium sidoides extract for acute respiratory tract infections (Review)", COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 1 January 2008 (2008-01-01), XP055289901, Retrieved from the Internet <URL:www.thecochranelibrary.com> [retrieved on 20160720] *

Also Published As

Publication number Publication date
KR101580119B1 (ko) 2015-12-29
CN105188669A (zh) 2015-12-23
EP2991624A1 (fr) 2016-03-09
RU2667638C2 (ru) 2018-09-21
RU2015142432A (ru) 2017-06-05
WO2014178617A1 (fr) 2014-11-06
HK1212912A1 (zh) 2016-06-24
MX2015014623A (es) 2016-03-01
BR112015026635A2 (pt) 2017-07-25
KR20140129459A (ko) 2014-11-07
PH12015502316A1 (en) 2016-02-10

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