EP2986704A4 - CONTACTLESS MICRO-DROPLECTOR DISPENSER AND CORRESPONDING METHOD - Google Patents
CONTACTLESS MICRO-DROPLECTOR DISPENSER AND CORRESPONDING METHODInfo
- Publication number
- EP2986704A4 EP2986704A4 EP14784764.4A EP14784764A EP2986704A4 EP 2986704 A4 EP2986704 A4 EP 2986704A4 EP 14784764 A EP14784764 A EP 14784764A EP 2986704 A4 EP2986704 A4 EP 2986704A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- droplector
- dispenser
- corresponding method
- contactless micro
- contactless
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0241—Drop counters; Drop formers
- B01L3/0265—Drop counters; Drop formers using valves to interrupt or meter fluid flow, e.g. using solenoids or metering valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0241—Drop counters; Drop formers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0241—Drop counters; Drop formers
- B01L3/0268—Drop counters; Drop formers using pulse dispensing or spraying, eg. inkjet type, piezo actuated ejection of droplets from capillaries
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/16—Reagents, handling or storing thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
- B01L2300/0838—Capillaries
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1894—Cooling means; Cryo cooling
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/02—Drop detachment mechanisms of single droplets from nozzles or pins
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/02—Drop detachment mechanisms of single droplets from nozzles or pins
- B01L2400/021—Drop detachment mechanisms of single droplets from nozzles or pins non contact spotting by inertia, i.e. abrupt deceleration of the nozzle or pin
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/082—Active control of flow resistance, e.g. flow controllers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/50—Cryostats
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1034—Transferring microquantities of liquid
Landscapes
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Fluid Mechanics (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
- Sampling And Sample Adjustment (AREA)
- Nozzles (AREA)
- Devices For Use In Laboratory Experiments (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361813700P | 2013-04-19 | 2013-04-19 | |
| PCT/US2014/033415 WO2014172152A1 (en) | 2013-04-19 | 2014-04-09 | Non-contact micro droplet dispenser and method |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| EP2986704A1 EP2986704A1 (en) | 2016-02-24 |
| EP2986704A4 true EP2986704A4 (en) | 2016-12-07 |
| EP2986704B1 EP2986704B1 (en) | 2019-04-03 |
Family
ID=51731763
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP14784764.4A Active EP2986704B1 (en) | 2013-04-19 | 2014-04-09 | Non-contact micro droplet dispenser |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US10486152B2 (en) |
| EP (1) | EP2986704B1 (en) |
| JP (1) | JP6433982B2 (en) |
| WO (1) | WO2014172152A1 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102016225209A1 (en) * | 2016-12-15 | 2018-06-21 | Hamilton Bonaduz Ag | Pipetting device for improved pulse-like liquid pipetting |
| CA3101599A1 (en) * | 2018-06-20 | 2019-12-26 | Gen-Probe Incorporated | Method and apparatus for freezing dispensed droplets of liquid |
| EP3944914A1 (en) * | 2020-07-30 | 2022-02-02 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Nozzle and method for forming microdroplets |
| CN114273106B (en) * | 2021-12-30 | 2023-02-03 | 杭州电子科技大学 | Pneumatic micro-droplet generator and preparation process thereof |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4977785A (en) * | 1988-02-19 | 1990-12-18 | Extrel Corporation | Method and apparatus for introduction of fluid streams into mass spectrometers and other gas phase detectors |
| WO1999031481A2 (en) * | 1997-12-12 | 1999-06-24 | Scientific Detectors Limited | Transport detector with oxide surface coating |
| US20030168586A1 (en) * | 2001-06-08 | 2003-09-11 | Kentaro Yamaguchi | Cold spray mass spectrometric device |
| WO2004088283A2 (en) * | 2003-03-28 | 2004-10-14 | Monsanto Technology Llc | Apparatus and methods for providing sex-sorted animal sperm |
| US20040238427A1 (en) * | 2003-05-29 | 2004-12-02 | Shuzo Maruyama | Fractionating/collecting device of liquid chromatograph |
| US20050147536A1 (en) * | 2004-01-06 | 2005-07-07 | Shimadzu Corporation | Fractionating apparatus |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3380584A (en) * | 1965-06-04 | 1968-04-30 | Atomic Energy Commission Usa | Particle separator |
| JPS5372773A (en) * | 1976-12-10 | 1978-06-28 | Hitachi Ltd | Direct reductive denitration method of ammonia |
| JP3137953B2 (en) * | 1999-03-30 | 2001-02-26 | 科学技術振興事業団 | Electrospray mass spectrometry method and apparatus |
| JP2001272640A (en) | 2000-03-27 | 2001-10-05 | Fujitsu Ltd | Liquid crystal dropping device and liquid crystal dropping method |
| HUP0302232A2 (en) * | 2000-05-09 | 2003-10-28 | Xy, Inc. | High purity x-chromosome bearing and y-chromosome bearing populations of spermatozoa |
| AUPR846501A0 (en) * | 2001-10-26 | 2001-11-15 | Btf Pty Ltd | A cytometer |
| ATE377763T1 (en) | 2002-01-25 | 2007-11-15 | Innovadyne Technologies Inc | CONTACTLESS METHOD FOR DISTRIBUTING SMALL LIQUID VOLUME |
| AU2004209426B2 (en) * | 2003-01-29 | 2008-04-17 | 454 Life Sciences Corporation | Method for preparing single-stranded DNA libraries |
| US20050014753A1 (en) * | 2003-04-04 | 2005-01-20 | Irm Llc | Novel compounds and compositions as protein kinase inhibitors |
| US7294309B1 (en) * | 2003-05-15 | 2007-11-13 | Takeda San Diego, Inc. | Small volume liquid handling apparatus and method |
| SG149007A1 (en) * | 2003-09-10 | 2009-01-29 | Althea Technologies Inc | Expression profiling using microarrays |
| JP2005292478A (en) * | 2004-03-31 | 2005-10-20 | Shibaura Mechatronics Corp | Method and apparatus for dropping liquid substance |
| EP1896610A2 (en) | 2005-05-03 | 2008-03-12 | Handylab, Inc. | Lyophilized pellets |
| AU2006287175A1 (en) * | 2005-09-01 | 2007-03-08 | Precision Therapeutics, Inc. | Chemo-sensitivity assays using tumor cells exhibiting persistent phenotypic characteristics |
| WO2007123720A2 (en) * | 2006-03-30 | 2007-11-01 | Cornell Research Foundation, Inc. | System and method for increased cooling rates in rapid cooling of small biological samples |
| US20100216230A1 (en) * | 2006-09-28 | 2010-08-26 | Cornell Research Foundation, Inc. | Systems for Increased Cooling and Thawing Rates of Protein Solutions and Cells for Optimized Cryopreservation and Recovery |
| US20090095825A1 (en) | 2007-10-11 | 2009-04-16 | Nordson Corporation | Dispenser nozzle having differential hardness |
-
2014
- 2014-04-09 WO PCT/US2014/033415 patent/WO2014172152A1/en not_active Ceased
- 2014-04-09 JP JP2016508965A patent/JP6433982B2/en active Active
- 2014-04-09 EP EP14784764.4A patent/EP2986704B1/en active Active
- 2014-04-09 US US14/784,757 patent/US10486152B2/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4977785A (en) * | 1988-02-19 | 1990-12-18 | Extrel Corporation | Method and apparatus for introduction of fluid streams into mass spectrometers and other gas phase detectors |
| WO1999031481A2 (en) * | 1997-12-12 | 1999-06-24 | Scientific Detectors Limited | Transport detector with oxide surface coating |
| US20030168586A1 (en) * | 2001-06-08 | 2003-09-11 | Kentaro Yamaguchi | Cold spray mass spectrometric device |
| WO2004088283A2 (en) * | 2003-03-28 | 2004-10-14 | Monsanto Technology Llc | Apparatus and methods for providing sex-sorted animal sperm |
| US20040238427A1 (en) * | 2003-05-29 | 2004-12-02 | Shuzo Maruyama | Fractionating/collecting device of liquid chromatograph |
| US20050147536A1 (en) * | 2004-01-06 | 2005-07-07 | Shimadzu Corporation | Fractionating apparatus |
Non-Patent Citations (1)
| Title |
|---|
| See also references of WO2014172152A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014172152A1 (en) | 2014-10-23 |
| US10486152B2 (en) | 2019-11-26 |
| EP2986704A1 (en) | 2016-02-24 |
| JP6433982B2 (en) | 2018-12-05 |
| EP2986704B1 (en) | 2019-04-03 |
| JP2016524521A (en) | 2016-08-18 |
| US20160074857A1 (en) | 2016-03-17 |
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