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EP2972244A4 - Dispositifs de diagnostic moléculaire à composants magnétiques - Google Patents

Dispositifs de diagnostic moléculaire à composants magnétiques

Info

Publication number
EP2972244A4
EP2972244A4 EP14767548.2A EP14767548A EP2972244A4 EP 2972244 A4 EP2972244 A4 EP 2972244A4 EP 14767548 A EP14767548 A EP 14767548A EP 2972244 A4 EP2972244 A4 EP 2972244A4
Authority
EP
European Patent Office
Prior art keywords
magnetic components
diagnostic devices
molecular diagnostic
molecular
devices
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14767548.2A
Other languages
German (de)
English (en)
Other versions
EP2972244A1 (fr
Inventor
Jason Rolland
John Thomas Connelly
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Diagnostics for All Inc
Original Assignee
Diagnostics for All Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diagnostics for All Inc filed Critical Diagnostics for All Inc
Publication of EP2972244A1 publication Critical patent/EP2972244A1/fr
Publication of EP2972244A4 publication Critical patent/EP2972244A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0605Metering of fluids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0647Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668Trapping microscopic beads
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0689Sealing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0636Integrated biosensor, microarrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0816Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0874Three dimensional network
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0887Laminated structure
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/12Specific details about materials
    • B01L2300/126Paper
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/16Surface properties and coatings
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/043Moving fluids with specific forces or mechanical means specific forces magnetic forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0633Valves, specific forms thereof with moving parts
    • B01L2400/065Valves, specific forms thereof with moving parts sliding valves

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP14767548.2A 2013-03-14 2014-03-14 Dispositifs de diagnostic moléculaire à composants magnétiques Withdrawn EP2972244A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361784938P 2013-03-14 2013-03-14
PCT/US2014/027894 WO2014152825A1 (fr) 2013-03-14 2014-03-14 Dispositifs de diagnostic moléculaire à composants magnétiques

Publications (2)

Publication Number Publication Date
EP2972244A1 EP2972244A1 (fr) 2016-01-20
EP2972244A4 true EP2972244A4 (fr) 2016-11-02

Family

ID=51581326

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14767548.2A Withdrawn EP2972244A4 (fr) 2013-03-14 2014-03-14 Dispositifs de diagnostic moléculaire à composants magnétiques

Country Status (3)

Country Link
US (1) US20160016166A1 (fr)
EP (1) EP2972244A4 (fr)
WO (1) WO2014152825A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113908897A (zh) * 2021-11-16 2022-01-11 中山大学 一种磁激励实现液滴操控的微流控装置及其操控方法

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* Cited by examiner, † Cited by third party
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WO2017014828A2 (fr) * 2015-05-20 2017-01-26 President And Fellows Of Harvard College Dispositif et procédé de détection électrochimique
US11278883B2 (en) 2016-12-30 2022-03-22 Roche Diagnostics Hematology, Inc. Sample processing systems and methods
US20180369808A1 (en) * 2017-06-23 2018-12-27 Group K Diagnostics, Inc. Microfluidic Device
TWI663400B (zh) * 2017-09-28 2019-06-21 國立臺灣大學 檢測試紙及檢測毒品的方法
EP3697537A4 (fr) 2017-10-18 2021-10-20 Group K Diagnostics, Inc. Dispositif microfluidique monocouche et ses procédés de fabrication et d'utilisation
GB201801019D0 (en) * 2018-01-22 2018-03-07 Q Linea Ab Sample holder
KR102041440B1 (ko) * 2018-02-12 2019-11-27 한국과학기술연구원 소형 다중 분자 진단시스템
KR102043036B1 (ko) * 2018-02-12 2019-11-11 한국과학기술연구원 소형 다중 분자 진단장치
WO2020028559A1 (fr) 2018-07-31 2020-02-06 University Of Florida Research Foundation Appareil et procédé pour effectuer la détection de micro-organismes
CN109337805A (zh) * 2018-09-28 2019-02-15 泰普生物科学(中国)有限公司 一种生物芯片杂交装置
USD879999S1 (en) 2018-11-02 2020-03-31 Group K Diagnostics, Inc. Microfluidic device
CN110358667A (zh) * 2019-06-28 2019-10-22 马鞍山众慧惠生生物科技有限公司 一种多样品滑动核酸检测装置
CN110452812A (zh) * 2019-06-28 2019-11-15 马鞍山众慧惠生生物科技有限公司 一种滑块式核酸检测装置
CN110452813A (zh) * 2019-06-28 2019-11-15 马鞍山众慧惠生生物科技有限公司 一种滑动核酸检测装置
WO2021011755A1 (fr) * 2019-07-16 2021-01-21 Saudi Arabian Oil Company Dispositifs microfluidiques polyvalents pour analyse chimique optique rapide sur site
EP4121558A4 (fr) * 2020-03-17 2023-11-29 Detect, Inc. Test de diagnostic rapide
US11773715B2 (en) 2020-09-03 2023-10-03 Saudi Arabian Oil Company Injecting multiple tracer tag fluids into a wellbore
US20220193659A1 (en) * 2020-12-17 2022-06-23 Philmedi Co.,Ltd. All-in-one kit for on-site molecular diagnosis and molecular diagnosis method using same
US11660595B2 (en) 2021-01-04 2023-05-30 Saudi Arabian Oil Company Microfluidic chip with multiple porosity regions for reservoir modeling
US11534759B2 (en) 2021-01-22 2022-12-27 Saudi Arabian Oil Company Microfluidic chip with mixed porosities for reservoir modeling
US12253467B2 (en) 2021-12-13 2025-03-18 Saudi Arabian Oil Company Determining partition coefficients of tracer analytes
US12000278B2 (en) 2021-12-16 2024-06-04 Saudi Arabian Oil Company Determining oil and water production rates in multiple production zones from a single production well

Citations (2)

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US6037168A (en) * 1997-12-31 2000-03-14 Cytonix Corporation Microbiological assembly comprising resealable closure means
US20080307117A1 (en) * 2004-04-08 2008-12-11 Judy Muller-Cohn Integration of sample storage and sample management for life science

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WO2006018044A1 (fr) * 2004-08-18 2006-02-23 Agilent Technologies, Inc. Ensemble micro-fluidique comprenant des dispositifs micro-fluidiques couples
US7888107B2 (en) * 2006-07-24 2011-02-15 Nanosphere, Inc. System using self-contained processing module for detecting nucleic acids
US20080317633A1 (en) * 2007-04-30 2008-12-25 Stc.Unm Multiplex lateral flow devices and methods
CN104722342B (zh) * 2009-03-24 2017-01-11 芝加哥大学 滑动式芯片装置和方法
US8337783B2 (en) * 2009-06-23 2012-12-25 The United States of America as represented by the Secretary of Commerce, the National Institute of Standards and Technology Magnetic connectors for microfluidic applications
WO2011068951A1 (fr) * 2009-12-03 2011-06-09 Vanderbilt University Matrice magnétique attachée réversiblement (mrat) et ses utilisations
CN102821861B (zh) * 2010-02-03 2015-03-25 哈佛大学校长及研究员协会 用于多重测定的装置和方法
JP6196661B2 (ja) * 2012-04-20 2017-09-13 スリップチップ, エルエルシー サンプル調製または自律分析のための流体デバイスおよびシステム

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6037168A (en) * 1997-12-31 2000-03-14 Cytonix Corporation Microbiological assembly comprising resealable closure means
US20080307117A1 (en) * 2004-04-08 2008-12-11 Judy Muller-Cohn Integration of sample storage and sample management for life science

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2014152825A1 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113908897A (zh) * 2021-11-16 2022-01-11 中山大学 一种磁激励实现液滴操控的微流控装置及其操控方法
CN113908897B (zh) * 2021-11-16 2022-07-12 中山大学 一种磁激励实现液滴操控的微流控装置及其操控方法

Also Published As

Publication number Publication date
WO2014152825A1 (fr) 2014-09-25
US20160016166A1 (en) 2016-01-21
EP2972244A1 (fr) 2016-01-20

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