[go: up one dir, main page]

EP2867370A4 - Méthodes de traitement du cancer du sein par une thérapie par la gemcitabine - Google Patents

Méthodes de traitement du cancer du sein par une thérapie par la gemcitabine

Info

Publication number
EP2867370A4
EP2867370A4 EP13808764.8A EP13808764A EP2867370A4 EP 2867370 A4 EP2867370 A4 EP 2867370A4 EP 13808764 A EP13808764 A EP 13808764A EP 2867370 A4 EP2867370 A4 EP 2867370A4
Authority
EP
European Patent Office
Prior art keywords
methods
breast cancer
treating breast
gemcitabine therapy
gemcitabine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP13808764.8A
Other languages
German (de)
English (en)
Other versions
EP2867370A2 (fr
Inventor
Sean M Ferree
J Wayne Cowens
Charlotte Levin Tykjaer Jorgensen
Torsten O Nielsen
Bent Ejlertsen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NS Wind Down Co Inc
Original Assignee
Nanostring Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanostring Technologies Inc filed Critical Nanostring Technologies Inc
Publication of EP2867370A2 publication Critical patent/EP2867370A2/fr
Publication of EP2867370A4 publication Critical patent/EP2867370A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Hospice & Palliative Care (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP13808764.8A 2012-06-29 2013-06-28 Méthodes de traitement du cancer du sein par une thérapie par la gemcitabine Withdrawn EP2867370A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261666355P 2012-06-29 2012-06-29
US201261733545P 2012-12-05 2012-12-05
PCT/US2013/048551 WO2014005010A2 (fr) 2012-06-29 2013-06-28 Méthodes de traitement du cancer du sein par une thérapie par la gemcitabine

Publications (2)

Publication Number Publication Date
EP2867370A2 EP2867370A2 (fr) 2015-05-06
EP2867370A4 true EP2867370A4 (fr) 2016-06-29

Family

ID=49784035

Family Applications (1)

Application Number Title Priority Date Filing Date
EP13808764.8A Withdrawn EP2867370A4 (fr) 2012-06-29 2013-06-28 Méthodes de traitement du cancer du sein par une thérapie par la gemcitabine

Country Status (7)

Country Link
US (1) US20140037620A1 (fr)
EP (1) EP2867370A4 (fr)
JP (1) JP2015530072A (fr)
AU (1) AU2013282391A1 (fr)
CA (1) CA2877378A1 (fr)
IL (1) IL236336A0 (fr)
WO (1) WO2014005010A2 (fr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1999883A4 (fr) 2006-03-14 2013-03-06 Divx Llc Système fédéré de gestion de droits numériques comprenant des systèmes de confiance
US9631239B2 (en) 2008-05-30 2017-04-25 University Of Utah Research Foundation Method of classifying a breast cancer instrinsic subtype
EP2384475A4 (fr) 2009-01-07 2014-01-22 Sonic Ip Inc Création singulière, collective et automatisée d'un guide multimédia pour un contenu en ligne
CA2782825C (fr) 2009-12-04 2016-04-26 Divx, Llc Systemes et procedes de transport de materiel cryptographique de train de bits elementaire
US9247312B2 (en) 2011-01-05 2016-01-26 Sonic Ip, Inc. Systems and methods for encoding source media in matroska container files for adaptive bitrate streaming using hypertext transfer protocol
CA2830240A1 (fr) 2011-03-15 2012-09-20 The University Of North Carolina At Chapell Hill Methodes de traitement du cancer du sein par une therapie par anthracycline
US9467708B2 (en) 2011-08-30 2016-10-11 Sonic Ip, Inc. Selection of resolutions for seamless resolution switching of multimedia content
US8964977B2 (en) 2011-09-01 2015-02-24 Sonic Ip, Inc. Systems and methods for saving encoded media streamed using adaptive bitrate streaming
US8909922B2 (en) 2011-09-01 2014-12-09 Sonic Ip, Inc. Systems and methods for playing back alternative streams of protected content protected using common cryptographic information
CA2857505A1 (fr) 2011-11-30 2013-06-06 The University Of North Carolina At Chapel Hill Procedes de traitement du cancer du sein avec une therapie au taxane
US9191457B2 (en) 2012-12-31 2015-11-17 Sonic Ip, Inc. Systems, methods, and media for controlling delivery of content
US9313510B2 (en) 2012-12-31 2016-04-12 Sonic Ip, Inc. Use of objective quality measures of streamed content to reduce streaming bandwidth
US9906785B2 (en) 2013-03-15 2018-02-27 Sonic Ip, Inc. Systems, methods, and media for transcoding video data according to encoding parameters indicated by received metadata
US10397292B2 (en) 2013-03-15 2019-08-27 Divx, Llc Systems, methods, and media for delivery of content
EP2997163A4 (fr) * 2013-05-13 2017-02-22 Nanostring Technologies, Inc Procédés de prédiction du risque de récurrence de cancer du sein de stade précoce à ganglions positifs
US9094737B2 (en) 2013-05-30 2015-07-28 Sonic Ip, Inc. Network video streaming with trick play based on separate trick play files
AU2014278537B2 (en) 2013-06-12 2018-04-19 The General Hospital Corporation Methods, kits, and systems for multiplexed detection of target molecules and uses thereof
US9967305B2 (en) 2013-06-28 2018-05-08 Divx, Llc Systems, methods, and media for streaming media content
US9866878B2 (en) 2014-04-05 2018-01-09 Sonic Ip, Inc. Systems and methods for encoding and playing back video at different frame rates using enhancement layers
US20180289689A1 (en) * 2014-10-27 2018-10-11 Ruprecht-Karls-Universität Heidelberg Use of ccr5 antagonists alone or in combination therapy for the treatment of cancer
CA2968376C (fr) 2014-11-21 2020-06-23 Nanostring Technologies, Inc. Sequencage sans enzyme ni amplification
WO2016085841A1 (fr) 2014-11-24 2016-06-02 Nanostring Technologies, Inc. Procédés et appareils pour la purification et l'imagerie de gènes
PL3423105T3 (pl) 2016-03-02 2021-10-25 Eisai R&D Management Co., Ltd. Koniugaty przeciwciało-lek oparte na erybulinie i sposoby zastosowania
CA3023566A1 (fr) 2016-05-16 2017-11-23 Nanostring Technologies, Inc. Procedes pour detecter des acides nucleiques dans un echantillon
US10415080B2 (en) 2016-11-21 2019-09-17 Nanostring Technologies, Inc. Chemical compositions and methods of using same
US10498795B2 (en) 2017-02-17 2019-12-03 Divx, Llc Systems and methods for adaptive switching between multiple content delivery networks during adaptive bitrate streaming
US11549139B2 (en) 2018-05-14 2023-01-10 Nanostring Technologies, Inc. Chemical compositions and methods of using same
WO2020214718A1 (fr) * 2019-04-16 2020-10-22 Memorial Sloan Kettering Cancer Center Gènes de signature rrm2 utilisés comme marqueurs pronostiques chez des patients atteints d'un cancer de la prostate
CN111455055B (zh) * 2020-04-28 2021-11-16 重庆浦洛通基因医学研究院有限公司 一种人类tyms基因表达量检测标准对照品
WO2022243702A1 (fr) 2021-05-21 2022-11-24 Emblation Limited Traitement par micro-ondes de tissu

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007061876A2 (fr) * 2005-11-23 2007-05-31 University Of Utah Research Foundation Methodes et compositions dans lesquelles sont utilises des genes intrinseques
WO2009158143A1 (fr) * 2008-05-30 2009-12-30 The University Of North Carolina At Chapel Hill Profils d’expression génique permettant de prévoir l’évolution d’un cancer du sein

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007061876A2 (fr) * 2005-11-23 2007-05-31 University Of Utah Research Foundation Methodes et compositions dans lesquelles sont utilises des genes intrinseques
WO2009158143A1 (fr) * 2008-05-30 2009-12-30 The University Of North Carolina At Chapel Hill Profils d’expression génique permettant de prévoir l’évolution d’un cancer du sein

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
K. HASTAK ET AL: "Synergistic Chemosensitivity of Triple-Negative Breast Cancer Cell Lines to Poly(ADP-Ribose) Polymerase Inhibition, Gemcitabine, and Cisplatin", CANCER RESEARCH, vol. 70, no. 20, 26 August 2010 (2010-08-26), US, pages 7970 - 7980, XP055231429, ISSN: 0008-5472, DOI: 10.1158/0008-5472.CAN-09-4521 *
KOSHY N ET AL: "Cisplatin-gemcitabine therapy in metastatic breast cancer: Improved outcome in triple negative breast cancer patients compared to non-triple negative patients", BREAST, EDINBURGH, GB, vol. 19, no. 3, 1 June 2010 (2010-06-01), pages 246 - 248, XP027088635, ISSN: 0960-9776, [retrieved on 20100315] *
See also references of WO2014005010A2 *

Also Published As

Publication number Publication date
IL236336A0 (en) 2015-02-26
AU2013282391A1 (en) 2015-01-22
EP2867370A2 (fr) 2015-05-06
US20140037620A1 (en) 2014-02-06
JP2015530072A (ja) 2015-10-15
CA2877378A1 (fr) 2014-01-03
WO2014005010A3 (fr) 2014-05-01
WO2014005010A2 (fr) 2014-01-03

Similar Documents

Publication Publication Date Title
EP2867370A4 (fr) Méthodes de traitement du cancer du sein par une thérapie par la gemcitabine
EP2685988A4 (fr) Méthodes de traitement du cancer du sein par une thérapie par anthracycline
IL288181A (en) Cancer treatment methods
EP2968191A4 (fr) Méthodes de traitement du cancer de la vessie
EP2739153A4 (fr) Traitement du cancer du sein
EP2920308A4 (fr) Traitement du cancer
EP2943192A4 (fr) Méthodes de traitement du cancer du pancréas
EP2908843A4 (fr) Méthode de traitement du cancer
EP2890720A4 (fr) Compositions et méthodes de traitement du cancer
EP2897620A4 (fr) Procédé de traitement du cancer
EP2892525A4 (fr) Méthodes de traitement de la dystrophie musculaire
HUE048876T2 (hu) Rákos megbetegedések kezelése
HUE047198T2 (hu) Fitokannabinoidok emlõrák kezelésére
EP2877572A4 (fr) Traitement par virus oncolytique de tumeurs résistantes
EP2968253A4 (fr) Méthodes de traitement de tumeur solide pédiatrique
EP2968208A4 (fr) Traitement de la cataplexie
EP2635286A4 (fr) Méthodes de traitement du cancer
EP2854839A4 (fr) Méthodes de traitement de la maladie c liaque
HRP20190046T1 (hr) Kombinirana terapija za liječenje raka
EP2968273A4 (fr) Méthodes de traitement de la dystrophie musculaire
EP2834262A4 (fr) Méthodes de traitement par une arginine déiminase
EP2785873A4 (fr) Procédés de traitement du cancer du sein avec une thérapie au taxane
EP2830633A4 (fr) Thérapie combinée destinée au traitement du cancer
EP2817011A4 (fr) Traitement du cancer
EP2694062A4 (fr) Procédés de traitement du cancer

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20141217

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

RIC1 Information provided on ipc code assigned before grant

Ipc: C12Q 1/68 20060101AFI20160202BHEP

Ipc: A61K 31/7068 20060101ALI20160202BHEP

A4 Supplementary search report drawn up and despatched

Effective date: 20160530

RIC1 Information provided on ipc code assigned before grant

Ipc: C12Q 1/68 20060101AFI20160523BHEP

Ipc: A61K 31/7068 20060101ALI20160523BHEP

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS

17Q First examination report despatched

Effective date: 20170508

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20170919