EP2850014B1 - Flacon pour produits préparés extemporanément, en particulier des produits médicinaux, pharmaceutiques, cosmétiques ou similaires - Google Patents
Flacon pour produits préparés extemporanément, en particulier des produits médicinaux, pharmaceutiques, cosmétiques ou similaires Download PDFInfo
- Publication number
- EP2850014B1 EP2850014B1 EP13729462.5A EP13729462A EP2850014B1 EP 2850014 B1 EP2850014 B1 EP 2850014B1 EP 13729462 A EP13729462 A EP 13729462A EP 2850014 B1 EP2850014 B1 EP 2850014B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- bottle
- cap
- fact
- foil
- tank
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Not-in-force
Links
- 238000002360 preparation method Methods 0.000 title claims description 14
- 239000002537 cosmetic Substances 0.000 title claims description 9
- 239000000126 substance Substances 0.000 claims description 46
- 239000002775 capsule Substances 0.000 claims description 41
- 239000011888 foil Substances 0.000 claims description 28
- 238000003825 pressing Methods 0.000 claims description 12
- 238000004806 packaging method and process Methods 0.000 claims description 7
- 230000008878 coupling Effects 0.000 claims description 6
- 238000010168 coupling process Methods 0.000 claims description 6
- 238000005859 coupling reaction Methods 0.000 claims description 6
- 238000007789 sealing Methods 0.000 claims description 6
- 230000014759 maintenance of location Effects 0.000 claims description 5
- 238000004891 communication Methods 0.000 claims description 4
- 238000003780 insertion Methods 0.000 claims description 2
- 230000037431 insertion Effects 0.000 claims description 2
- 229910052751 metal Inorganic materials 0.000 claims description 2
- 239000002184 metal Substances 0.000 claims description 2
- 239000000047 product Substances 0.000 description 38
- 239000007788 liquid Substances 0.000 description 9
- 238000005520 cutting process Methods 0.000 description 5
- 238000004026 adhesive bonding Methods 0.000 description 2
- 239000004411 aluminium Substances 0.000 description 2
- 229910052782 aluminium Inorganic materials 0.000 description 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 238000005304 joining Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000035699 permeability Effects 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- BLDFSDCBQJUWFG-UHFFFAOYSA-N 2-(methylamino)-1,2-diphenylethanol Chemical compound C=1C=CC=CC=1C(NC)C(O)C1=CC=CC=C1 BLDFSDCBQJUWFG-UHFFFAOYSA-N 0.000 description 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 239000004035 construction material Substances 0.000 description 1
- 235000015872 dietary supplement Nutrition 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 229920001903 high density polyethylene Polymers 0.000 description 1
- 239000004700 high-density polyethylene Substances 0.000 description 1
- 229920000092 linear low density polyethylene Polymers 0.000 description 1
- 239000004707 linear low-density polyethylene Substances 0.000 description 1
- 229920001684 low density polyethylene Polymers 0.000 description 1
- 239000004702 low-density polyethylene Substances 0.000 description 1
- 210000003141 lower extremity Anatomy 0.000 description 1
- 230000007257 malfunction Effects 0.000 description 1
- 229920001179 medium density polyethylene Polymers 0.000 description 1
- 239000004701 medium-density polyethylene Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000002861 polymer material Substances 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000001364 upper extremity Anatomy 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D51/00—Closures not otherwise provided for
- B65D51/24—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes
- B65D51/28—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials
- B65D51/2807—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials the closure presenting means for placing the additional articles or materials in contact with the main contents by acting on a part of the closure without removing the closure, e.g. by pushing down, pulling up, rotating or turning a part of the closure, or upon initial opening of the container
- B65D51/2814—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials the closure presenting means for placing the additional articles or materials in contact with the main contents by acting on a part of the closure without removing the closure, e.g. by pushing down, pulling up, rotating or turning a part of the closure, or upon initial opening of the container the additional article or materials being released by piercing, cutting or tearing an element enclosing it
- B65D51/2821—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials the closure presenting means for placing the additional articles or materials in contact with the main contents by acting on a part of the closure without removing the closure, e.g. by pushing down, pulling up, rotating or turning a part of the closure, or upon initial opening of the container the additional article or materials being released by piercing, cutting or tearing an element enclosing it said element being a blister, a capsule or like sealed container
Definitions
- the present invention relates to a bottle for extemporaneous-preparation products, particularly medicinal, pharmaceutical, cosmetic products or the like, according to the preamble of claim 1.
- extemporaneous-preparation products are known, i.e., products made up of the solution or of the mixing of at least two different substances, of which, e.g., one in the liquid state and the other in the powder state, which are kept separate the one from the other until the time of use.
- bottles such as those described and illustrated in the patent document EP 0 963 325 .
- Such bottles are essentially made up of a tank which is closed on the bottom and which extends at the top in a neck, at the top of which is defined a dispensing mouth; inside the tank a first substance is contained, generally in the liquid state.
- a container of a second substance which is made up of a hollow cylindrical body closed at the bottom by a breakable bottom and open at the top; the bottom of the container, as long as this remains intact, separates the second substance from the first.
- a cutting element which is made up of a tubular body, the lower extremity of which is sectioned according to an oblique plane or which is bevel shaped and the upper extremity of which extends beyond the top opening of the container.
- the cutting element is axially sliding with respect to the container between a non-interference configuration, wherein it is placed above the intact bottom of the container itself, and a cutting configuration, wherein, pushed towards the bottom of the container, it cuts this along the perimeter edge putting the container, thus opened, into communication with the tank.
- the known bottles furthermore, have a cover cap which is associated with the neck of the tank by means of a threaded coupling; the lower edge of the cap is temporarily secured, along a breakage line, to a seal ring secured to the neck of the tank and having a weakened axial line in correspondence to which it opens.
- annular relief is defined which, after the cap has been screwed onto the neck of the tank, couples with the upper edge of the container, which is elastically deformable in a centripetal direction, to form a single body piece with this.
- the cap is screwed onto the neck of the tank to break the seal ring which detaches from this and opens.
- the screwing up of the cap causes the sliding of the cutting element inside the container until the bottom of the latter is cut; the second substance is then poured from the container into the tank, inside which it mixes with the first to form the product.
- the cap has simply to be unscrewed to also remove, integral with this, the container and the cutting element opening the dispensing mouth of the tank.
- vapours coming from the outside environment and/or those released by the liquid substance in the tank permeate, in part, inside the container where a powdery, often hygroscopic substance is generally present.
- the powdery substance absorbs the vapours released by the liquid substance impregnating itself with these and becoming dense in agglomerates.
- the container When, at the time of preparing the product, the container is opened and placed in communication with the tank, the agglomerates which have formed tend to remain inside the container and, even when they have been poured into the tank, they have difficulty in dissolving and dispersing themselves completely in the liquid substance.
- composition of the product thus formed does not correspond to that provided for it; in the event of the product being a drug or a medicinal, this causes an indeterminable alteration of the contents of its active ingredients and of the dosage established for it and, therefore, a disadvantageous modification of the therapy studied for a patient.
- Permeability to vapours is further accentuated in correspondence to the bottom of the container which, being of a breakable type, generally has a reduced thickness and/or is fastened to the body of the container along weakened lines of even more reduced thickness.
- bottles are known like those illustrated in the documents EP 1 186 548 and EP 1 858 774 , wherein the container containing the second substance defines an insulating interspace to hinder the transit of the vapours released by the liquid substance.
- the capsule is kept in correspondence to the dispensing mouth and meant to be perforated by means of a perforator element integrated in the cap.
- the perforator is arranged above the blistered capsule and, once operated, crosses the blistered capsule from side to side so as to permit the release of the second substance.
- the perforation furthermore, determines a non-uniform tearing of the blistered capsule, with the risk of a number of fragments of same becoming separated from the cap and being swallowed by the user together with the product.
- the bottle shown in WO 2012/035417 has the blistered capsule glued or sealed to the top of the cap; in case of the glue or the sealing yielding, therefore, serious malfunctions could occur, such as the fall of the blistered capsule into the tank and its perforation failure, thereby completely preventing the mixing of the substances and the formation of the product.
- PCT/IB2012/000690 shows a bottle wherein the blistered capsule, instead of being perforated, is crushed by means of a pressing element integrated in the cap.
- the pressing element acts on one face of the blistered capsule, which remains integral and does not break, while the opposite face, because of the pressure applied on the blistered capsule, is broken open, thus releasing the second substance inside the tank.
- the blistered capsule is housed and retained in correspondence to the dispensing mouth of the tank thanks to a bush fitted at least partially in the neck of the tank.
- the bottle made this way is therefore fabricated in the form of four separate components, i.e., the tank, the pressing element integrated in the cap, the blistered capsule and the bush.
- PCT/IB2012/000690 is nevertheless also susceptible to further upgrading aimed, in particular, at increasing its efficiency and ease of use, besides reducing its number of components.
- Another kind of bottle is disclosed in the patent document GB 2405868 .
- the main aim of the present invention is to provide a bottle for extemporaneous-preparation products, particularly medicinal, pharmaceutical, cosmetic products or the like, which does in fact allow maintaining the substances making up the product perfectly separate from one another and isolated until the time of product preparation.
- Another object of the present invention consists in providing a bottle which can be used and opened in a simple, practical and easy way by users without requiring any particular effort on their part.
- a further object of the present invention consists in providing a bottle able to ensure the very best water seal between the different components and, at the same time, great sturdiness and stability, so that it offers highly-reliable and efficient use.
- Not the least object of the present invention consists in providing a bottle the costs and production times of which are reduced, which is easy to assemble and which permits limiting the quantities of component parts and construction materials used for its production.
- Another object of the present invention is to provide a bottle for extemporaneous-preparation products, particularly medicinal, pharmaceutical, cosmetic products or the like that allows overcoming the mentioned drawbacks of the state of the art within the ambit of a simple, rational, easy and effective to use as well as low cost solution.
- extemporaneous-preparation products are meant products obtainable through the solution or the mixing of at least two different substances which are kept separate until the time of product use.
- One of the two substances is generally in powder or granular form, while the other is generally in liquid state.
- the bottle 1 comprises a tank 2 for containing a first substantially liquid substance 3.
- the tank 2 is substantially shaped like a bottle, a phial or the like.
- the tank 2 has a central axis A, a closed bottom 4 and, towards the top, extends in a neck 5.
- the top of the neck 5 ends in a dispensing mouth 6 to allow the product to come out, once this has been prepared.
- top of the neck 5 is meant the part arranged higher when the tank 2 is placed in the normal collocation position, i.e., with the central axis A vertical, the closed bottom 4 turned downwards and the neck 5 turned upwards.
- a blistered capsule 7, 8 can be placed for containing a second substantially powdered substance 9.
- the blistered capsule 7, 8 has:
- the first foil 7 is substantially curved with the exception of the perimeter edge 7b, which is substantially flat.
- At least one between the first foil 7 and the second foil 8 comprises at least one layer of metal, preferably aluminium, able to prevent the transit of humidity and, above all, any vapours escaping from the first substance 3 contained in the tank 2.
- both the first foil 7 and the second foil 8 each have a layer of aluminium, if necessary combined with one or more layers of other material, e.g. plastic or the like (LLDPE, LDPE, MDPE, HDPE).
- plastic or the like LLDPE, LDPE, MDPE, HDPE
- the blistered capsule 7, 8 formed this way can be positioned in the proximity of the neck 5.
- the blistered capsule 7,8 is positioned so the second foil 8 is facing and turned towards the inside of the tank 2, i.e., downwards, while the first foil 7 is turned upwards.
- the inner volume of the blistered capsule 7, 8 is temporarily separated from the inner volume of the tank 2 and is suitable for being placed in communication with this for mixing the first substance 3 and the second substance 9 to form the product.
- tank 2 With the tank 2 is associable at least one removable cap 10 which covers the dispensing mouth 6.
- the cap 10 in particular, can be associated with the tank 2 by means of a threaded coupling.
- the cap 10 in fact, comprises a tubular wall 11 which can be placed around the neck 5; both the tubular wall 11 and the neck 5 are cylinder shaped with round cross section extending along the central axis A, with the tubular wall 11 having an internal threading 12 engageable with an external threading 13 obtained on the neck 5.
- the bottle 1 has anti-tampering seal means 14, 15 suitable for making evident the removal of the cap 10 from the tank 2.
- the anti-tampering seal means 14, 15 comprise a seal ring 14 which is made in a single body piece with the cap 10 along a tearable line 15 obtained at the base of the tubular wall 11.
- the tearable line 15, e.g., is defined by a series of bridges with weakened section placed in between the seal ring 14 and the base of the tubular wall 11.
- the seal ring 14 can be fastened to the tank 2 by means of a slot coupling.
- Such coupling is made up, e.g., of an annular relief 16 protruding from the outer face of the neck 5 and of a corresponding annular protrusion 17 defined inside the seal ring 14.
- the cap 10 At the top of the tubular wall 11, the cap 10 has an annular disc 18 which extends from the tubular wall 11 towards the central axis A.
- the cap 10 has an actuator element 19 moving between a packaging configuration, wherein the actuator element 19 is kept substantially spaced away from the blistered capsule 7, 8, and a release configuration, wherein the actuator element 19 is arranged in contact against the blistered capsule 7, 8 and causes its opening for the outflow of the first substance 3 and its mixing with the second substance 9 to form the product.
- the actuator element 19 is made up of a pressing element suitable for coming into contact with the first foil 7 of the blistered capsule 7, 8 and causing the deformation without breakage of the first foil 7 and the breakage of the second foil 8.
- the actuator element 19 consists of a perforator element having a sharp profile able to cross both the foils of the blistered capsule 7, 8.
- the actuator element 19 and the cap 10 are made in a single body piece and are joined along a pre-breaking line 20 which is breakable for the switch of the actuator element 19 from the packaging configuration to the release configuration.
- the actuator element 19 and the cap 10 are made joined and, once the cap 10 has been placed on the neck 5 of the tank 2, the actuator element 19 remains far enough from the blistered capsule 7, 8 so as not to negatively affect its integrity.
- the pressing element 19 is shaped so as to define a tubular body 21, having a closed side 22 arranged above and an open side 23 arranged below.
- the open side 23, in point of fact, consists of an annular surface suitable for coming into contact with the first foil 7 of the blistered capsule 7, 8 and deforming it.
- actuator element 19 and the cap 10 retention means 24, 25 are provided between the actuator element 19 and the cap 10 retention means 24, 25 for retaining the actuator element 19 in the release configuration.
- the retention means 24, 25 comprise, e.g., at least one grip recess 24, obtained on at least one between the actuator element 19 and the cap 10, and at least one fastening tooth 25, obtained on the other between the actuator element 19 and the cap 10 and insertable into the grip recess 24 when the actuator element 19 has reached the release configuration.
- the grip recess 24 is obtained at the top of the actuator element 19, on its outer side face, while the fastening tooth 25 is obtained on the cap 10 in correspondence to the pre-breaking line 20.
- the cap 10 comprises an annular wall 26 having an outer side surface 27 and an annular edge 28 with which is associated the perimeter edge 7b of the first foil 7.
- the annular wall 26 extends downwards from the annular disc 18 and axially ends in the annular edge 28.
- the annular edge 28 lies on a plane transversal to the central axis A and is substantially flat, so as to facilitate joining to the perimeter edge 7b; the union between the annular edge 28 and the perimeter edge 7b occurs e.g. by means of sealing, heat sealing, ultrasonic sealing, gluing or the like.
- the annular wall 26 and the tubular wall 11 of the cap 10 are substantially coaxial with one another and fitted inside one another, with the tubular wall 11 outside the annular wall 26.
- the tubular wall 11 and the annular wall 26 are spaced away so as to define, between themselves and the annular disc 18, an annular interspace into which the top of the neck 5 can be fitted.
- the neck 5 defines an end portion 29 having an inner side surface 30 and an annular seat 31 which lies on a plane transversal to the central axis A.
- the annular wall 26 can be fitted in the end portion 29 with the outer side surface 27 in seal contact against the inner side surface 30 and with the blistered capsule 7, 8 blocked between the annular edge 28 and the annular seat 31.
- the outer side surface 27 is tapered towards the annular edge 28 to define an invitation profile guiding the insertion into the inner side surface 30.
- the outer side surface 27 has a truncated-cone shape with vertex turned downwards.
- the outer side surface 27 is oversized with respect to the inner side surface 30, i.e., it has a larger diameter compared to that of the inner side surface 30.
- annular wall 26 can be inserted in the end portion 29 with interference, exploiting at least in part the deformability of the material making up the annular wall 26 and the end portion 29 to ensure the sought seal effect between the tank 2 and the cap 10.
- the axial extension of the annular wall 26 and of the end portion 29 is such as to place the annular edge 28 and the annular seat 31 at a very short distance which determines the crushing of the perimeter of the blistered capsule 7, 8 on both faces, ensuring this stays in position.
- the operation of the bottle 1 is the following.
- the bottle 1 is manufactured in the form of three separate component parts ( figure 1 ): the tank 2 containing the first substance 3, the blistered capsule 7, 8 containing the second substance 9, and the cap 10, which integrates the pressing element 19 and the seal ring 14.
- the assembly of bottle 1 occurs by stably joining (e.g., by means of sealing or gluing) the perimeter edge 7b of the blistered capsule 7, 8 to the annular edge 28 and, subsequently, fitting and screwing the cap 10 over the neck 5.
- the annular wall 26 is forced to enter with interference in the end portion 29, ensuring the side seal between the outer side surface 27 of the annular wall 26 and the inner side surface 30 of the end portion 29.
- the pressing element 19 is thus forced to switch from packaging configuration to release configuration, wherein it comes into contact with the blistered capsule 7, 8 deforming its first foil 7 without breaking it.
- the pressure applied on the second substance 9 by means of the deformation of the first foil 7 leads to the breaking of the second foil 8, and to the fall by gravity of the second substance 9 through the neck 5 and its pouring inside the tank 2 to form the product ( figure 3 ).
- the cap 10 simply has to be unscrewed from the neck 5.
- Such operation determines the simultaneous removal of the blistered capsule 7, 8, which is stably joined to the annular edge 28, and of the pressing element 19, which remains associated with the cap 10 thanks to the retention means 24, 25.
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Closures For Containers (AREA)
- Package Specialized In Special Use (AREA)
Claims (14)
- Flacon (1) pour des produits à préparation extemporanée, notamment des produits médicinaux, pharmaceutiques, cosmétiques ou similaires, comprenant :- au moins un réservoir (2) pour le confinement d'une première substance (3), qui possède au moins un goulot (5) aboutissant dans une bouche de distribution (6) ;- au moins une capsule à blister (7, 8) pour le confinement d'une seconde substance (9), qui comprend :- une première feuille de conditionnement (7) déformable et conformée pour définir une cavité de confinement (7a) de ladite seconde substance (9) et un rebord de périmètre (7b), et- une seconde feuille de conditionnement (8) ruptible et plate, qui est associée audit rebord de périmètre (7b) pour fermer ladite cavité de confinement (7a) ;ladite capsule à blister (7, 8) étant placée à proximité dudit goulot (5), dans lequel le volume intérieur de ladite capsule à blister (7, 8) est temporairement séparé du volume intérieur dudit réservoir (2) et peut être placé en communication avec celui-ci pour mélanger la première substance (3) et la seconde substance (9) ensemble pour constituer un produit ; et- au moins un capuchon amovible (10), qui peut être associe audit réservoir (2) pour recouvrir ladite bouche de distribution (6) et qui comprend au moins un élément actionneur (19) évoluant entre une configuration de conditionnement, dans laquelle ledit élément actionneur (19) est maintenu espacé de ladite capsule à blister (7, 8), et une configuration de libération, dans laquelle ledit élément actionneur (19) est agencé au contact de ladite capsule à blister (7, 8), provoquant l'ouverture de cette derrière permettant la sortie de la seconde substance (9) et son mélange avec la première substance (3) pour constituer ledit produit ;caractérisé en ce que :- ledit capuchon (10) comprend une paroi annulaire (26) ayant une surface latérale extérieure (27) et un bord annulaire (28) avec lequel ledit rebord de périmètre (7b) de la première feuille de conditionnement (7) est associé ; et- ledit goulot (5) comprend une portion d'extrémité (29) ayant une surface latérale intérieure (30) et un siège annulaire (31) ;ladite paroi annulaire (26) pouvant être insérée dans ladite portion d'extrémité (29) avec ladite surface latérale extérieure (27) en contact étanche contre ladite surface latérale intérieure (30) et ladite capsule à blister (7, 8) agencée entre ledit bord annulaire (28) et ledit siège annulaire (31), dans lequel au moins une partie de ladite surface latérale extérieure (27) est surdimensionnée par rapport à ladite surface latérale intérieure (30) et ladite paroi annulaire (26) peut être insérée dans ladite portion d'extrémité (29) avec interférence.
- Flacon (1) selon la revendication 1, caractérisé en ce que ladite surface latérale extérieure (27) et biseautée vers ledit bord annulaire (28) pour définir un profil d'invitation guidant l'insertion dans ladite surface latérale intérieure (30).
- Flacon (1) selon l'une ou plusieurs des revendications précédentes, caractérisé en ce que ladite capsule à blister (7, 8) est agencée avec ladite seconde feuille de conditionnement (8) en regard de et orientée vers l'intérieur dudit réservoir (2).
- Flacon (1) selon la revendication 3, caractérisé en ce que ledit élément actionneur (19) est un élément d'appui entrant en contact avec ladite première feuille de conditionnement (7) et provoquant la déformation sans rupture de ladite première feuille de conditionnement (7) et la rupture de ladite seconde feuille de conditionnement (8).
- Flacon (1) selon la revendication 4, caractérisé en ce que ledit élément d'appui (19) comprend un corps tubulaire (21) ayant un côté ouvert (23) entrant en contact avec ladite première feuille de conditionnement (7).
- Flacon (1) selon l'une ou plusieurs des revendications précédentes, caractérisé en ce que ledit élément actionneur (19) et ledit capuchon (10) sont réalisés en une seule pièce.
- Flacon (1) selon la revendication 6, caractérisé en ce que ledit élément actionneur (19) et ledit capuchon (10) sont solidarisés entre eux le long d'une ligne de pré-rupture (20) qui peut être rompue pour faire passer ledit élément actionneur (19) de ladite configuration de conditionnement à ladite configuration de libération.
- Flacon (1) selon l'une ou plusieurs des revendications précédentes, caractérisé en ce qu'il comprend des moyens de rétention (24, 25) pour ledit élément actionneur (19) dans ladite configuration de libération.
- Flacon (1) selon la revendication 8, caractérisé en ce que lesdits moyens de rétention (24. 25) comprennent au moins un renfoncement d'accrochage (24), obtenu sur au moins l'un parmi ledit élément actionneur (19) et ledit capuchon (10), et au moins une dent d'accrochage (25), qui est obtenue sur l'autre parmi ledit élément actionneur (19) et ledit capuchon (10) et est insérée dans ledit renfoncement d'accrochage (24) lorsque ledit élément actionneur (19) est dans la configuration de libération.
- Flacon (1) selon l'une ou plusieurs des revendications précédentes, caractérisé en ce que ledit capuchon (10) peut être associé audit réservoir (2) au moyen d'un couplage fileté.
- Flacon (1) selon la revendication 10, caractérisé en ce que ledit capuchon (10) comprend une paroi tubulaire (11) qui est coaxiale et extérieure à ladite paroi annulaire (26) et possède un filetage interne (12) pouvant s'engager avec un filetage externe (13) obtenu sur ledit goulot (5).
- Flacon (1) selon l'une ou plusieurs des revendications précédentes, caractérisé en ce qu'il comprend des moyens de fermeture inviolables (14, 15) aptes à rendre évident le premier retrait dudit capuchon (10) dudit réservoir (2).
- Flacon (1) selon la revendication 12, caractérisé en ce que lesdits moyens de fermeture inviolables (14, 15) comprennent une bague de scellement (14) qui est réalisée en une seule pièce avec ledit capuchon (10) le long d'une ligne d'arrachage (15) et qui peut être fixée audit réservoir (2).
- Flacon (1) selon l'une ou plusieurs des revendications précédentes, caractérisé en ce que au moins l'une parmi ladite première feuille de conditionnement (7) et ladite seconde feuille de conditionnement (8) comprend au moins une couche métallique.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000132A ITMO20120132A1 (it) | 2012-05-15 | 2012-05-15 | Flacone per prodotti a preparazione estemporanea, particolarmente medicinali, farmaceutici, cosmetici o simili |
| PCT/IB2013/053614 WO2013171621A1 (fr) | 2012-05-15 | 2013-05-06 | Flacon pour produits préparés extemporanément, en particulier des produits médicinaux, pharmaceutiques, cosmétiques ou similaires |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP2850014A1 EP2850014A1 (fr) | 2015-03-25 |
| EP2850014B1 true EP2850014B1 (fr) | 2016-07-13 |
Family
ID=46321296
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP13729462.5A Not-in-force EP2850014B1 (fr) | 2012-05-15 | 2013-05-06 | Flacon pour produits préparés extemporanément, en particulier des produits médicinaux, pharmaceutiques, cosmétiques ou similaires |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP2850014B1 (fr) |
| ES (1) | ES2590507T3 (fr) |
| IT (1) | ITMO20120132A1 (fr) |
| WO (1) | WO2013171621A1 (fr) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2673933T3 (es) * | 2014-02-24 | 2018-06-26 | Montefarmaco Otc S.P.A. | Botella de dosis única y tapón medidor asociado mejorado |
| FR3057743B1 (fr) | 2016-10-21 | 2018-10-26 | B2B Cosmetics | Systeme melangeur pour fabriquer un produit cosmetique et capsule cosmetique |
| AU2017100804B4 (en) * | 2017-06-15 | 2018-03-01 | Ambrosios Kambouris | Cap for packing containers including an integral powder or liquid |
| FR3081299B1 (fr) | 2018-05-23 | 2020-09-11 | Oreal | Dispositif de preparation d'une compostion cosmetique, et procede associe |
| FR3081298B1 (fr) * | 2018-05-23 | 2022-12-23 | Oreal | Dispositif de preparation d'une composition cosmetique, jeu de capsules et procede de preparation associes |
| FR3081301B1 (fr) | 2018-05-23 | 2020-06-12 | L'oreal | Dispositif de preparation d'une composition cosmetique, jeu de capsules et procede de preparation associes |
| FR3081302B1 (fr) * | 2018-05-23 | 2021-12-10 | Oreal | Dispositif de preparation d'une composition cosmetique et procede associe |
| FR3088811B1 (fr) * | 2018-11-23 | 2022-03-18 | Oreal | Dispositif de préparation d’une composition cosmétique et procédé de préparation associé |
| WO2021236625A1 (fr) | 2020-05-19 | 2021-11-25 | 10X Genomics, Inc. | Cassettes et instrumentation d'électrophorèse |
| AU2021294334A1 (en) | 2020-06-25 | 2023-02-02 | 10X Genomics, Inc. | Spatial analysis of DNA methylation |
| EP4301870B1 (fr) | 2021-03-18 | 2025-01-15 | 10X Genomics, Inc. | Capture multiplex de gène et expression de protéines à partir d'un échantillon biologique |
| CN114476357A (zh) * | 2022-03-17 | 2022-05-13 | 大兴安岭至臻尚品寒带生物技术有限公司 | 一种医用固液速混装置 |
| CN116588505A (zh) * | 2023-05-25 | 2023-08-15 | 大兴安岭至臻尚品寒带生物技术有限公司 | 一种带有独立料仓的瓶盖 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1292677B1 (it) | 1997-02-28 | 1999-02-11 | Bormioli Metalplast Spa | Confezione per mantenere separati dei prodotti prima dell'uso. |
| US6098795A (en) | 1997-10-14 | 2000-08-08 | Mollstam; Bo | Device for adding a component to a package |
| DE20015613U1 (de) | 2000-09-08 | 2000-11-30 | Georg Menshen GmbH & Co. KG, 57413 Finnentrop | Zweikomponentenspender |
| DE60333231D1 (de) * | 2003-01-03 | 2010-08-12 | Sji Ltd | Mischspender |
| DE10341112A1 (de) * | 2003-09-05 | 2005-03-31 | Li-Li Yehhsu | Behälter mit separaten Speicherkammern |
| KR100893388B1 (ko) * | 2004-09-29 | 2009-04-17 | 가부시키가이샤 요시노 고교쇼 | 2가지 액체 등의 혼합용기 |
| ITMO20050057A1 (it) | 2005-03-15 | 2006-09-16 | Lameplast Spa | Confezione per prodotti a preparazione estemporanea, particolarmente medicinali, farmaceutici,cosmetici o simili. |
| IT1402348B1 (it) | 2010-09-17 | 2013-08-30 | Biofarma S P A | Dispositivo di chisura per un flacone e flacone comprendente tale dispositivo di chiusura |
-
2012
- 2012-05-15 IT IT000132A patent/ITMO20120132A1/it unknown
-
2013
- 2013-05-06 ES ES13729462.5T patent/ES2590507T3/es active Active
- 2013-05-06 EP EP13729462.5A patent/EP2850014B1/fr not_active Not-in-force
- 2013-05-06 WO PCT/IB2013/053614 patent/WO2013171621A1/fr not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| ES2590507T3 (es) | 2016-11-22 |
| EP2850014A1 (fr) | 2015-03-25 |
| WO2013171621A1 (fr) | 2013-11-21 |
| ITMO20120132A1 (it) | 2013-11-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP2850014B1 (fr) | Flacon pour produits préparés extemporanément, en particulier des produits médicinaux, pharmaceutiques, cosmétiques ou similaires | |
| EP2697135B1 (fr) | Flacon pour la préparation improvisée de produits, en particulier de produits médicaux, pharmaceutiques ou cosmétiques | |
| EP1858774B1 (fr) | Emballage de produits prepares extemporanement, particulierement des produits medicinaux, pharmaceutiques, cosmetiques ou analogues | |
| US8151985B2 (en) | Containers for storing at least two substances for subsequent mixing | |
| KR101932937B1 (ko) | 배출기구를 가지는 병 | |
| US9592940B2 (en) | Ingredient release spout | |
| JP5819430B2 (ja) | 活性成分を投与するためのカプセル付きプラスチック閉鎖体 | |
| CN103221316B (zh) | 容器的关闭装置以及包括所述关闭装置的容器 | |
| JP2008532873A (ja) | いわゆる「プッシュプル」クロージャを含む容器向けの容器クロージャ | |
| US8960423B2 (en) | Oxygen-impereable, fillable closure with a push button for triggering | |
| EP2922767B1 (fr) | Dispositif de conservation étanche aux fluides d'une substance à mélanger à une autre substance contenue dans un récipient | |
| WO2001083319A1 (fr) | Melange de plusieurs constituants | |
| AU2018234458B2 (en) | Doser cap for liquid container | |
| EP2674371A1 (fr) | Bouchon de bouteille pour la conservation de substances devant être maintenues séparées jusqu'à leur utilisation | |
| MXPA06008076A (es) | Capsula que incorpora un dosificador y capa de seguridad que se puede abrir, en particular para envases de dosis individuales. | |
| EP2121468B1 (fr) | Contenant pour produits fluides ou en poudre | |
| KR102017235B1 (ko) | 스크류 타입 이종물질 혼합기 | |
| US20190177057A1 (en) | Packaging for extemporaneous preparation products, particularly medicinal, pharmaceutical, cosmetic products or the like |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 20141209 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
| AX | Request for extension of the european patent |
Extension state: BA ME |
|
| DAX | Request for extension of the european patent (deleted) | ||
| GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
| INTG | Intention to grant announced |
Effective date: 20160209 |
|
| GRAS | Grant fee paid |
Free format text: ORIGINAL CODE: EPIDOSNIGR3 |
|
| GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
| AK | Designated contracting states |
Kind code of ref document: B1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
| REG | Reference to a national code |
Ref country code: GB Ref legal event code: FG4D |
|
| REG | Reference to a national code |
Ref country code: AT Ref legal event code: REF Ref document number: 812092 Country of ref document: AT Kind code of ref document: T Effective date: 20160715 Ref country code: CH Ref legal event code: EP |
|
| REG | Reference to a national code |
Ref country code: IE Ref legal event code: FG4D |
|
| REG | Reference to a national code |
Ref country code: DE Ref legal event code: R096 Ref document number: 602013009391 Country of ref document: DE |
|
| REG | Reference to a national code |
Ref country code: LT Ref legal event code: MG4D |
|
| REG | Reference to a national code |
Ref country code: NL Ref legal event code: MP Effective date: 20160713 |
|
| REG | Reference to a national code |
Ref country code: ES Ref legal event code: FG2A Ref document number: 2590507 Country of ref document: ES Kind code of ref document: T3 Effective date: 20161122 |
|
| REG | Reference to a national code |
Ref country code: AT Ref legal event code: MK05 Ref document number: 812092 Country of ref document: AT Kind code of ref document: T Effective date: 20160713 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: RS Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160713 Ref country code: FI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160713 Ref country code: NO Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20161013 Ref country code: LT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160713 Ref country code: NL Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160713 Ref country code: HR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160713 Ref country code: IS Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20161113 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LV Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160713 Ref country code: SE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160713 Ref country code: AT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160713 Ref country code: GR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20161014 Ref country code: PT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20161114 Ref country code: BE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160713 Ref country code: PL Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160713 |
|
| REG | Reference to a national code |
Ref country code: DE Ref legal event code: R097 Ref document number: 602013009391 Country of ref document: DE |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: RO Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160713 Ref country code: EE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160713 |
|
| PLBE | No opposition filed within time limit |
Free format text: ORIGINAL CODE: 0009261 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: BG Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20161013 Ref country code: DK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160713 Ref country code: SK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160713 Ref country code: CZ Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160713 Ref country code: SM Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160713 |
|
| 26N | No opposition filed |
Effective date: 20170418 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160713 Ref country code: LU Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20170531 |
|
| REG | Reference to a national code |
Ref country code: DE Ref legal event code: R119 Ref document number: 602013009391 Country of ref document: DE |
|
| REG | Reference to a national code |
Ref country code: CH Ref legal event code: PL |
|
| GBPC | Gb: european patent ceased through non-payment of renewal fee |
Effective date: 20170506 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: MC Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160713 |
|
| REG | Reference to a national code |
Ref country code: IE Ref legal event code: MM4A |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LI Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20170531 Ref country code: CH Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20170531 |
|
| REG | Reference to a national code |
Ref country code: FR Ref legal event code: ST Effective date: 20180131 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LU Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20170506 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20170506 Ref country code: DE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20171201 Ref country code: GB Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20170506 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: FR Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20170531 |
|
| REG | Reference to a national code |
Ref country code: ES Ref legal event code: FD2A Effective date: 20180627 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: ES Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20170507 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: MT Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20170506 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: AL Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160713 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: HU Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT; INVALID AB INITIO Effective date: 20130506 |
|
| PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: IT Payment date: 20190514 Year of fee payment: 7 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: CY Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160713 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: MK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160713 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: TR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160713 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IT Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20200506 |