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EP2763540A4 - Compositions et procédés d'évaluation et de traitement de maladies et de troubles inflammatoires - Google Patents

Compositions et procédés d'évaluation et de traitement de maladies et de troubles inflammatoires

Info

Publication number
EP2763540A4
EP2763540A4 EP12829361.0A EP12829361A EP2763540A4 EP 2763540 A4 EP2763540 A4 EP 2763540A4 EP 12829361 A EP12829361 A EP 12829361A EP 2763540 A4 EP2763540 A4 EP 2763540A4
Authority
EP
European Patent Office
Prior art keywords
diseases
evaluation
compositions
treatment
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP12829361.0A
Other languages
German (de)
English (en)
Other versions
EP2763540A1 (fr
Inventor
Eran Elinav
Richard A Flavell
Till Strowig
Jorge H Mejia
Chengcheng Jin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yale University
Original Assignee
Yale University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yale University filed Critical Yale University
Publication of EP2763540A1 publication Critical patent/EP2763540A1/fr
Publication of EP2763540A4 publication Critical patent/EP2763540A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP12829361.0A 2011-09-09 2012-04-16 Compositions et procédés d'évaluation et de traitement de maladies et de troubles inflammatoires Withdrawn EP2763540A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161532902P 2011-09-09 2011-09-09
US201261584988P 2012-01-10 2012-01-10
PCT/US2012/033753 WO2013036290A1 (fr) 2011-09-09 2012-04-16 Compositions et procédés d'évaluation et de traitement de maladies et de troubles inflammatoires

Publications (2)

Publication Number Publication Date
EP2763540A1 EP2763540A1 (fr) 2014-08-13
EP2763540A4 true EP2763540A4 (fr) 2015-04-22

Family

ID=47832488

Family Applications (1)

Application Number Title Priority Date Filing Date
EP12829361.0A Withdrawn EP2763540A4 (fr) 2011-09-09 2012-04-16 Compositions et procédés d'évaluation et de traitement de maladies et de troubles inflammatoires

Country Status (2)

Country Link
EP (1) EP2763540A4 (fr)
WO (1) WO2013036290A1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011503104A (ja) 2007-11-09 2011-01-27 カリフォルニア インスティテュート オブ テクノロジー 免疫調節化合物ならびに関連組成物および方法
WO2011127302A2 (fr) 2010-04-07 2011-10-13 Yue Shen Véhicule destiné à distribuer un composé à une muqueuse et compositions, procédés et systèmes apparentés
WO2013009945A1 (fr) 2011-07-12 2013-01-17 The Brigham And Women's Hospital, Inc. Compositions de psa contenant des lipides, procédés d'isolement et procédés pour les utiliser
EP2909334B1 (fr) 2012-10-17 2020-06-24 Enterome Signatures génétiques de troubles métaboliques liés au foie et de la maladie de crohn
EP2969012A4 (fr) 2013-03-12 2016-09-14 Univ Yale Compositions et méthodes pour identifier des microbes liés à des anticorps sécrétoires
EP2994161B1 (fr) 2013-05-10 2020-10-28 California Institute of Technology Prévention et traitement probiotiques du cancer du côlon
WO2015066625A1 (fr) * 2013-11-01 2015-05-07 Washington University Méthodes pour établir et restaurer la fonction normale du microbiote intestinal chez un sujet en ayant besoin
FI127671B (en) * 2014-05-28 2018-11-30 Filip Scheperjans Method for diagnostics of Parkinson’s disease
EP3188741A4 (fr) 2014-08-28 2018-03-28 Yale University Compositions et méthodes pour le traitement d'une maladie ou d'un trouble inflammatoire
US9968616B2 (en) 2014-10-25 2018-05-15 The Chinese University Of Hong Kong Discovery of FDA-approved drugs as inhibitors of fatty acid binding protein 4 using molecular docking screening
EP3679798B1 (fr) * 2015-02-03 2021-11-17 Mayo Foundation for Medical Education and Research Procédés et matériaux permettant d'évaluer et de traiter l'arthrite
WO2016201342A1 (fr) 2015-06-10 2016-12-15 California Institute Of Technology Traitement du sepsis, compositions, méthodes et systèmes associés
CA2997211A1 (fr) 2015-08-19 2017-02-23 President And Fellows Of Harvard College Compositions de psa lipides et procedes associes
CA3030974A1 (fr) 2016-07-15 2018-01-18 President And Fellows Of Harvard College Compositions de glycolipide et procedes d'utilisation
WO2021262601A1 (fr) * 2020-06-22 2021-12-30 Regeneron Pharmaceuticals, Inc. Traitement de l'obésité au moyen d'inhibiteurs du récepteur 75 couplé à la protéine g (gpr75)

Citations (4)

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WO2004045525A2 (fr) * 2002-11-15 2004-06-03 Morehouse School Of Medicine Anticorps anti-chimiokines et anticorps anti-recepteurs associes et utilisations de ces anticorps pour inhiber des inflammations
WO2005016226A2 (fr) * 2003-08-14 2005-02-24 Hadasit Medical Research Services & Development Ltd. Compositions pharmaceutiques comprenant des antagonistes de ccr5
WO2011043654A1 (fr) * 2009-10-05 2011-04-14 Aak Patent B.V. Procédé de diagnostic du syndrome du côlon irritable
WO2011082218A1 (fr) * 2009-12-31 2011-07-07 Ira Milton Trachtman Compositions et procédés pour traitement et prophylaxie d'une maladie intestinale inflammatoire

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US4256108A (en) 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
US4160452A (en) 1977-04-07 1979-07-10 Alza Corporation Osmotic system having laminated wall comprising semipermeable lamina and microporous lamina
US4265874A (en) 1980-04-25 1981-05-05 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
US5023243A (en) 1981-10-23 1991-06-11 Molecular Biosystems, Inc. Oligonucleotide therapeutic agent and method of making same
US5190931A (en) 1983-10-20 1993-03-02 The Research Foundation Of State University Of New York Regulation of gene expression by employing translational inhibition of MRNA utilizing interfering complementary MRNA
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
US5168053A (en) 1989-03-24 1992-12-01 Yale University Cleavage of targeted RNA by RNAase P
US5459039A (en) 1989-05-12 1995-10-17 Duke University Methods for mapping genetic mutations
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5424186A (en) 1989-06-07 1995-06-13 Affymax Technologies N.V. Very large scale immobilized polymer synthesis
US5288644A (en) 1990-04-04 1994-02-22 The Rockefeller University Instrument and method for the sequencing of genome
DE69132531T2 (de) 1990-12-06 2001-09-13 Affymetrix, Inc. (N.D.Ges.D.Staates Delaware) Verbindungen und ihre Verwendung in einer binären Synthesestrategie
US5384261A (en) 1991-11-22 1995-01-24 Affymax Technologies N.V. Very large scale immobilized polymer synthesis using mechanically directed flow paths
AU8126694A (en) 1993-10-26 1995-05-22 Affymax Technologies N.V. Arrays of nucleic acid probes on biological chips
US6159693A (en) 1998-03-13 2000-12-12 Promega Corporation Nucleic acid detection
US6270974B1 (en) 1998-03-13 2001-08-07 Promega Corporation Exogenous nucleic acid detection
EP2280085A3 (fr) * 2004-11-01 2011-02-23 George Mason University Compositions et méthodes pour le diagnostic de troubles du colon
WO2010094734A2 (fr) * 2009-02-19 2010-08-26 Biofocus Dpi B.V. Procédés d'identification de composés utiles pour le diagnostic et le traitement de maladies liées à une inflammation
SI2470671T1 (sl) * 2009-08-28 2015-04-30 Regeneron Pharmaceuticals, Inc. Antikinska protitelesa, ki se veĺ˝ejo na veäś kemokinov cc

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004045525A2 (fr) * 2002-11-15 2004-06-03 Morehouse School Of Medicine Anticorps anti-chimiokines et anticorps anti-recepteurs associes et utilisations de ces anticorps pour inhiber des inflammations
WO2005016226A2 (fr) * 2003-08-14 2005-02-24 Hadasit Medical Research Services & Development Ltd. Compositions pharmaceutiques comprenant des antagonistes de ccr5
WO2011043654A1 (fr) * 2009-10-05 2011-04-14 Aak Patent B.V. Procédé de diagnostic du syndrome du côlon irritable
WO2011082218A1 (fr) * 2009-12-31 2011-07-07 Ira Milton Trachtman Compositions et procédés pour traitement et prophylaxie d'une maladie intestinale inflammatoire

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DELPHINE M SAULNIER ET AL: "Gastrointestinal Microbiome Signatures of Pediatric Patients With Irritable Bowel Syndrome", GASTROENTEROLOGY, ELSEVIER, PHILADELPHIA, PA, vol. 141, no. 5, 24 June 2011 (2011-06-24), pages 1782 - 1791, XP028325678, ISSN: 0016-5085, [retrieved on 20110708], DOI: 10.1053/J.GASTRO.2011.06.072 *
ERAN ELINAV ET AL: "NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis", CELL, CELL PRESS, US, vol. 145, no. 5, 22 April 2011 (2011-04-22), pages 745 - 757, XP028221175, ISSN: 0092-8674, [retrieved on 20110502], DOI: 10.1016/J.CELL.2011.04.022 *
See also references of WO2013036290A1 *
YANFEI CHEN ET AL: "Characterization of fecal microbial communities in patients with liver cirrhosis", HEPATOLOGY, vol. 54, no. 2, 26 June 2011 (2011-06-26), pages 562 - 572, XP055159513, ISSN: 0270-9139, DOI: 10.1002/hep.24423 *
YOUNES J. ERRAHALI ET AL: "CCL26-Targeted siRNA Treatment of Alveolar Type II Cells Decreases Expression of CCR3-Binding Chemokines and Reduces Eosinophil Migration: Implications in Asthma Therapy", JOURNAL OF INTERFERON & CYTOKINE RESEARCH, vol. 29, no. 4, 1 April 2009 (2009-04-01), pages 227 - 239, XP055175655, ISSN: 1079-9907, DOI: 10.1089/jir.2008.0051 *

Also Published As

Publication number Publication date
EP2763540A1 (fr) 2014-08-13
WO2013036290A1 (fr) 2013-03-14

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