EP2651368B1 - Device for introducing filling material into capsules - Google Patents
Device for introducing filling material into capsules Download PDFInfo
- Publication number
- EP2651368B1 EP2651368B1 EP20110778626 EP11778626A EP2651368B1 EP 2651368 B1 EP2651368 B1 EP 2651368B1 EP 20110778626 EP20110778626 EP 20110778626 EP 11778626 A EP11778626 A EP 11778626A EP 2651368 B1 EP2651368 B1 EP 2651368B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- filling
- capsule
- station
- capsule holder
- row
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 239000002775 capsule Substances 0.000 title claims description 128
- 239000000463 material Substances 0.000 title claims description 10
- 239000003814 drug Substances 0.000 description 4
- 238000003860 storage Methods 0.000 description 4
- 238000005429 filling process Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000004140 cleaning Methods 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 108010010803 Gelatin Proteins 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
- A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
- A61J3/074—Filling capsules; Related operations
Definitions
- the present invention relates to a device for filling, in particular powdery, contents in capsules.
- Capsules eg made of gelatin, which are produced from essentially cylindrical hollow shapes with hemispherical end regions are frequently used, in particular for medicaments.
- One half of the capsules are filled with a medium, in particular a drug, and then the other half of the capsule is placed in order to obtain a closed capsule.
- the filling of the capsule takes place here in filling machines, which in particular must ensure a high accuracy in the filling of the respective quantities in order to prevent incorrect dosages of a drug.
- capsules often have longer filling times, which limits an output of a filling machine.
- a device for metering and filling of powdery contents in containers in which two filling units are arranged side by side in series.
- a partial filling by the first filling unit and a final final filling by the second filling unit can take place.
- EP 1 413 434 A1 shows a device according to the preamble of claim 1.
- the inventive device for filling of product in capsules with the features of claim 1 has the advantage over that in comparison with the known devices, an increase in performance by a improved filling of the capsules is achieved.
- the device comprises a filling device for filling the capsules and a capsule holder, wherein the capsule holder at least one row of several receptacles, in which the capsules to be filled are arranged.
- a station arrangement is provided with a plurality of stations, which are arranged one after the other.
- a movement device which allows a relative filling movement between the filling device and the capsule holder at a capsule filling station, wherein the filling device occupies at least a first filling position for filling a first capsule and a second filling position for filling a second capsule relative to the capsule holder.
- the filling device occupies at least a first filling position for filling a first capsule and a second filling position for filling a second capsule relative to the capsule holder.
- the station arrangement comprises a station wheel with a plurality of capsule holders. This allows a very efficient flow during the filling process can be achieved.
- the movement device performs a relative movement between the filling device and the capsule holder in the radial direction.
- a relative movement in a first direction and a second direction in a horizontal plane is possible between the filling device and the capsule holder.
- a plurality of parallel rows of capsules can be filled.
- the first direction perpendicular to the second direction.
- the filling station has a particularly compact design and it can be easily brought a sufficient amount of filling in the different filling positions.
- the metering wheel has at least a first filling chamber and a second filling chamber and the metering rotates during a movement process from the first filling position to the second filling position to bring a filling chamber filled with filling material in the filling position and the empty filling chamber again fill. Due to the simultaneous movements of the dosing wheel and the capsule holder, capsule filling can be carried out in rapid succession both in the first filling position and in the second filling position.
- a filling process of a capsule at the capsule filling station by means of the filling device is the shortest of all individual processes in the station arrangement.
- a filling process in the capsule filling station takes half as long as the next shortest process in a station.
- the capsule holder comprises a first series of receptacles and a second series of receptacles which are arranged parallel to one another.
- a plurality of capsules can be arranged in a small area. More preferably, several more parallel rows, e.g. three or four or five rows.
- the device further comprises a second capsule filling station with a second filling device.
- a second capsule filling station with a second filling device.
- the movement device is arranged on the filling device and the filling device is moved relative to the capsule holder. In this way, a high variability of the relative movement between the filling device and the capsule holder can be ensured.
- the moving device comprises a driven cam or a linear motor or a servomotor.
- a reliable movement of the moving device in the radial and vertical directions with short cycle times is possible.
- an intermediate gear or as an intermediate member a carriage combined with a coupling or deflection can be provided to convert a generated vertical movement into a horizontal movement by means of deflection.
- this can also be a screw (rack / pinion) can be used.
- the drive can also be positioned below the machine level or base plate of the station.
- the movement device is arranged on the capsule holder in order to move the capsule holder relative to the filling device.
- the capsule holder has to be removed from the station wheel and has to be moved relative to the filling device.
- the movement device comprises a guide element with curved path.
- a slotted guide is further provided to bring the capsule holder in a first position and a second position.
- a radial movement of the capsule holder during the downtime of the device is made possible.
- the drive of the scenery can be done purely mechanically or via a cam mechanism by means of a linear or servo motor. For smaller outputs, the use of a pneumatic drive is also possible as an alternative.
- the filling device preferably comprises a plurality of filling units, which are arranged in series, at the same time several To fill capsules in a row.
- a number of filling units corresponds to a number of capsule receptacles in a row of the capsule holder.
- the filling device is a pressure-vacuum filling device, wherein a filling amount is sucked by means of vacuum and discharged by means of pressure.
- the filling device comprises a flexible product feed, which is provided between the reservoir and filling station.
- a flexible product feed which is provided between the reservoir and filling station. This enables optimal product feeding to the moving filling station. For better cleaning and to prevent influences on the product properties, it is advantageous to produce the steel feeder and to make it pivotable. Between the reservoir or the filling station and the pivotable product supply each flexible seals are provided.
- FIGS. 1 to 5 a device 20 for filling of powdery product 21 according to a first preferred embodiment described in detail.
- FIG. 1 shows an overall view of the device 20, which includes a station wheel 40 with a total of twelve stations 1 to 12.
- a total of twelve capsule holders 30 are arranged along the circumference, wherein each capsule holder 30 has a plurality of receptacles 31, 32 for receiving capsules 22.
- the receptacles 31, 32 are arranged in each capsule holder 30 in two rows, namely a first row R1 and a second row R2 parallel to each other.
- a rotational direction of the station wheel 40 is indicated by the arrow A.
- the stations of the station wheel 40 are as follows. At station 1, empty, closed capsules, which comprise a capsule bottom part 23 and a capsule top part 24, are supplied from a supply. The capsules are introduced individually into a receptacle 31 of the capsule holder 30.
- the capsules 22 are opened, that is, the capsule top 24 is removed from the capsule bottom 23 so that the capsule bottom 23 remains in the receptacle 31.
- the feeding and opening of the capsules can also take place at the same station. Also, e.g. at station 1, the first row and at station 2, the second row are filled with capsules, and at the stations preferably also be opened the same.
- the stations 3 and 4 are not occupied in this embodiment.
- the station 5 is a filling station in which the opened capsules 22 are filled.
- a filling device 25 is provided, which in detail in the Figures 2 and 3 is shown.
- the filling device 25 comprises a metering wheel 26 and a storage hopper 27, in which the powdery filling material 21 is arranged.
- the filling device 25 comprises a movement device, not visible here, which moves the filling device 25 in two directions, namely a first direction X and a second direction Y.
- the two directions X, Y are perpendicular to each other (see. FIG. 1 ) and move the filling device 25 in a horizontal plane.
- the movement device preferably comprises two separate drives which move the filling device 25 in the two directions X, Y.
- FIG. 2 shows a start position of the filling, wherein the filling device 25 is disposed over a receptacle 31 of the first row R1 of the recordings and is thus positioned in a first filling position.
- the metering wheel 26 has a first metering chamber 28a and a second metering chamber 28b. In the in FIG. 2 shown position is sucked at a receiving position E in the first metering chamber 28a by means of vacuum, a small filling amount 80. Thereafter, the metering wheel 26 rotates in the direction of arrow B by 180 ° and the small filling amount 80 at a discharge position F by means of compressed air, so that the filling amount 80 falls into the capsule base 23 into it. How out FIG.
- the filling device 25 then performs a movement in the direction X, so that the dispensing position F is thus positioned in a second filling position on a receptacle 32 of the second row R2.
- a second filling 51 is then filled in the same way in the capsule bottom 23 in the receptacle 32 of the second row R2.
- the filling device 25 is moved in the direction Y and filled the capsule base 23 in the next shot. Then, the filler 25 can be moved again in the X direction to fill the next capsule bottom 23 in the first row R1.
- the filling device can also be moved to a second filling position in the second direction Y after filling the capsule lower part 23 previously filled in the first row R1 in order to fill a further capsule bottom part 23 in the first row R1.
- a movement in the second direction Y can also take place in order to fill a further capsule lower part 23 in the second row R2.
- the metering wheel 26 may also have four metering chambers arranged at an angle of 90 ° to one another, wherein the metering wheel 26 is further rotated by 90 ° in each case for receiving and discharging the contents 21.
- the filling device may also comprise a plurality of filling units in series, the number of filling units being equal to, or a multiple or a subset thereof, of the number of receptacles 31, 32 in the row R1 and R2.
- a further filling device may also be provided at the station 6, so that, for example, the first filling device at the station 5 performs a partial filling and the second filling device 6 performs a final final filling and accurate metering of the filling quantity.
- a weighing device may be provided to check the filled capsules.
- the station 8 is an ejection station in which damaged or unfilled or incorrectly filled capsules can be discarded.
- the capsule tops 24 are again positioned over the now filled capsule bottoms 23 and in the station 10, the capsules are closed again. This can be done for example by lowering the capsule caps on the capsule parts.
- the station 11 is the dispensing station of the filled capsules and the station 12 is a cleaning station in which the capsule holders 30 are cleaned in order to avoid incorrect filling of the capsules into the receptacles 31.
- FIG. 4 shows a arranged on the filling device 25 moving device 50, which performs a relative movement between the filling device 25 and the capsule holder 30 in the X direction.
- the moving device 50 in this case comprises a carriage 53 which is fixed at one end to the filling device 25 and is slidably supported or stored in a holding device 55 by means of a bearing 54.
- the opposite end of the carriage 53 is rotatably mounted on a cam 51, which is driven by a drive 52, for. B. a servomotor, is moved in the direction of arrow K and thus moves the carriage 53 together with the filling device 25 in the X direction.
- the filling device 25 also has a flexible product supply 200, which is tubular and is arranged between a reservoir 210 and the storage hopper 27 pivotally. As a result, an optimal supply of the filling material 21 from the storage container 210 to the moving filling station 25 is achieved.
- a movement device 60 can also be provided, from which a cam 61 together with drive 62 is arranged below a base plate 67 of the station 5.
- the Moving device 60 has a mounted on the base plate 67 holding device 68, in which a first carriage 63 is slidably supported by a first bearing 64.
- One end of the carriage 63 is rotatably connected to the cam 61, which is driven by a drive 62, preferably a form of a servomotor.
- the opposite end of the first carriage 63 is connected via a deflection 65 with a second carriage 66 which is displaceably mounted in the holding device 68 by means of a second bearing 67.
- FIG. 5 As can be seen, in this case a substantially vertical movement of the first carriage 63 in a direction S in a movement in the direction X is generated, which causes the displacement of the filling device 25 from the first row R1 to the second row R2 of the capsule holder 30.
- a drive for the movement of the filling device 25 in the Y direction is in the FIGS. 4 and 5 not shown for simplicity of illustration, wherein the drive in the Y direction may be the same as that in the X direction. Alternatively, a linear drive can be provided.
- FIGS. 6 to 9 a device 20 for filling of powdery product according to a second preferred embodiment described in detail.
- the same or functionally identical components are designated here by the same reference numerals as in the first embodiment.
- the device 20 in this second embodiment comprises a movement device 70 which is arranged on the station wheel 40 and a relative movement between the filling device 25 and the capsule holder 30 in FIG radial direction or X-direction performs.
- the movement device 70 has a guide element 71 with a curved path 72.
- a slotted guide 73 with a recess 74 formed therein (see FIG. FIG. 8 ) intended.
- a holder 75 is attached (see FIG. FIG. 6 ), by means of which a capsule holder 30 is fixed to the movement device 70 via a rod 76 fixed in the holder 75.
- the capsule holder 30 is moved in the radial direction or X-direction relative to the filling device 25, not shown here, in accordance with the shape of the curved path 72.
- the slide guide 73 is located in an in FIG. 6 and FIG. 8 each represented by an arrow first position B, so that a row R1 of capsule holder 30 located in the capsule base 23 (see FIG. FIG. 6 ) can be filled.
- the slide guide 73 is displaced from the first position B into a second position C represented by an arrow when the station wheel 40 is at a standstill FIG. 9 is illustrated.
- a filling of capsule parts 23 in a second row R2 of a capsule holder 30 'positioned in this way can then take place (see FIG. FIG. 7 ).
- both the filling device and the capsule holder can be moved.
- a faster positioning of the capsule holder used and the filling station is possible, whereby a further increase in machine efficiency can be achieved in an individual application.
- this also increases the machine outlay.
- the filling device 25 has a filling time which is half a time of a station having the second shortest processing time. This makes it possible to comply with a given clock of the station wheel 40 very well, in particular, when using a filling device with five filling units, both the first row R1 and the second row R2 of the capsule holder 30 can be filled in only one station.
- the device according to the invention for filling contents 21 into capsules 22 is preferably used for filling capsules with medicaments.
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Description
Die vorliegende Erfindung betrifft eine Vorrichtung zum Abfüllen von, insbesondere pulverförmigem, Füllgut in Kapseln.The present invention relates to a device for filling, in particular powdery, contents in capsules.
Insbesondere für Medikamente werden häufig Kapseln, z.B. aus Gelatine, verwendet, welche aus im Wesentlichen zylindrischen Hohlformen mit halbkugelförmigen Endbereichen hergestellt sind. Eine Hälfte der Kapseln wird mit einem Füllgut, insbesondere einem Medikament, gefüllt und anschließend wird die andere Hälfte der Kapsel aufgesetzt, um eine geschlossene Kapsel zu erhalten. Die Befüllung der Kapsel erfolgt hierbei in Füllmaschinen, welche insbesondere eine hohe Genauigkeit bei der Abfüllung der jeweiligen Mengen sicherstellen müssen, um Fehldosierungen eines Medikaments zu verhindern. Von daher ergeben sich häufig längere Füllzeiten der Kapseln, was eine Ausbringungsmenge einer Füllmaschine beschränkt. Aus der
Die erfindungsgemäße Vorrichtung zum Abfüllen von Füllgut in Kapseln mit den Merkmalen des Anspruchs 1 weist demgegenüber den Vorteil auf, dass im Vergleich mit den bekannten Vorrichtungen eine Leistungssteigerung durch eine verbesserte Befüllung der Kapseln erreicht wird. Hierbei kann erfindungsgemäß insbesondere auf mehrere Füllstationen verzichtet werden und trotzdem eine schnelle Füllzeit erreicht werden. Dies wird erfindungsgemäß dadurch erreicht, dass die Vorrichtung eine Füllvorrichtung zum Befüllen der Kapseln und einen Kapselhalter umfasst, wobei der Kapselhalter wenigstens eine Reihe von mehreren Aufnahmen, in welchen die zu befüllenden Kapseln angeordnet sind, aufweist. Ferner ist eine Stationsanordnung mit einer Mehrzahl von Stationen vorgesehen, welche nacheinander angeordnet sind. Hierbei ist eine Bewegungsvorrichtung vorgesehen, welche an einer Kapselfüllstation eine Relativbewegung zwischen der Füllvorrichtung und dem Kapselhalter ermöglicht, wobei die Füllvorrichtung gegenüber dem Kapselhalter wenigstens eine erste Füllstellung zum Befüllen einer ersten Kapsel und eine zweite Füllstellung zum Befüllen einer zweiten Kapsel einnimmt. Hierdurch können mittels einer einzigen Füllvorrichtung durch Vorsehen der Relativbewegung zwischen der Füllvorrichtung und dem Kapselhalter alle im Kapselhalter aufgenommenen Kapseln durch Einnehmen mehrerer Füllstellungen gefüllt werden. Somit kann die Füllvorrichtung die im Kapselhalter befindlichen Kapseln sowohl in der ersten als auch der zweiten Füllstellung befüllen. Die Vorrichtung zeichnet sich ferner insbesondere durch einen sehr geringen baulichen Aufwand aus.
Weiterhin weist die Füllstation erfindungsgemäß ein Dosierrad und einen Vorratstrichter zur Aufnahme des Füllguts auf. Dadurch kann ohne großen baulichen Aufwand eine betriebssichere Führung des Füllguts in das Dosierrad erreicht werden.The inventive device for filling of product in capsules with the features of
Furthermore, the filling station according to the invention has a metering wheel and a storage hopper for receiving the contents. As a result, a reliable operation of the filling material can be achieved in the metering without great structural complexity.
Die Unteransprüche zeigen bevorzugte Weiterbildungen der Erfindung.The dependent claims show preferred developments of the invention.
Besonders bevorzugt umfasst die Stationsanordnung ein Stationsrad mit einer Vielzahl von Kapselhaltern. Hierdurch kann ein sehr effizienter Durchlauf während des Füllvorgangs erreicht werden. Die Bewegungsvorrichtung führt dabei eine Relativbewegung zwischen der Füllvorrichtung und dem Kapselhalter in radialer Richtung aus.Particularly preferably, the station arrangement comprises a station wheel with a plurality of capsule holders. This allows a very efficient flow during the filling process can be achieved. The movement device performs a relative movement between the filling device and the capsule holder in the radial direction.
Vorzugsweise ist dabei zwischen der Füllvorrichtung und dem Kapselhalter eine Relativbewegung in eine erste Richtung und eine zweite Richtung in einer horizontalen Ebene möglich. Hierdurch können insbesondere mehrere, parallele Reihen von Kapseln, gefüllt werden. Besonders bevorzugt ist dabei die erste Richtung senkrecht zur zweiten Richtung.Preferably, a relative movement in a first direction and a second direction in a horizontal plane is possible between the filling device and the capsule holder. As a result, in particular a plurality of parallel rows of capsules can be filled. Particularly preferred is the first direction perpendicular to the second direction.
Zudem weist die Füllstation einen besonders kompakten Aufbau auf und es kann problemlos eine ausreichende Füllmenge in die unterschiedlichen Füllstellungen gebracht werden.In addition, the filling station has a particularly compact design and it can be easily brought a sufficient amount of filling in the different filling positions.
Gemäß einer bevorzugten Ausgestaltung der Erfindung weist das Dosierrad wenigstens eine erste Füllkammer und eine zweite Füllkammer auf und das Dosierrad dreht sich während eines Bewegungsvorgangs von der ersten Füllstellung zur zweiten Füllstellung, um eine mit Füllgut gefüllte Füllkammer in die Füllposition zu bringen und die leere Füllkammer wieder aufzufüllen. Aufgrund der simultanen Bewegungen des Dosierrads und des Kapselhalters können Befüllungen von Kapseln sowohl in der ersten Füllstellung als auch der zweiten Füllstellung in rascher Folge ausgeführt werden.According to a preferred embodiment of the invention, the metering wheel has at least a first filling chamber and a second filling chamber and the metering rotates during a movement process from the first filling position to the second filling position to bring a filling chamber filled with filling material in the filling position and the empty filling chamber again fill. Due to the simultaneous movements of the dosing wheel and the capsule holder, capsule filling can be carried out in rapid succession both in the first filling position and in the second filling position.
Gemäß einer weiteren bevorzugten Ausgestaltung der Erfindung ist ein Füllvorgang einer Kapsel an der Kapselfüllstation mittels der Füllvorrichtung der kürzeste aller einzelnen Vorgänge in der Stationsanordnung. Besonders bevorzugt dauert ein Füllvorgang in der Kapselfüllstation dabei halb so lang wie der nächst kürzeste Vorgang in einer Station.According to a further preferred embodiment of the invention, a filling process of a capsule at the capsule filling station by means of the filling device is the shortest of all individual processes in the station arrangement. Particularly preferably, a filling process in the capsule filling station takes half as long as the next shortest process in a station.
Besonders bevorzugt umfasst der Kapselhalter eine erste Reihe von Aufnahmen und eine zweite Reihe von Aufnahmen, welche parallel zueinander angeordnet sind. Hierdurch kann eine Vielzahl von Kapseln auf einer geringen Fläche angeordnet werden. Weiter bevorzugt können noch mehrere zueinander parallele Reihen, z.B. drei oder vier oder fünf Reihen, angeordnet werden.Particularly preferably, the capsule holder comprises a first series of receptacles and a second series of receptacles which are arranged parallel to one another. As a result, a plurality of capsules can be arranged in a small area. More preferably, several more parallel rows, e.g. three or four or five rows.
Gemäß einer bevorzugten Ausgestaltung der Erfindung umfasst die Vorrichtung ferner eine zweite Kapselfüllstation mit einer zweiten Füllvorrichtung. Hierdurch ist es möglich, dass beispielsweise in der ersten Füllstation eine Teilbefüllung und in der zweiten Füllstation eine Endbefüllung der Kapseln erfolgt.According to a preferred embodiment of the invention, the device further comprises a second capsule filling station with a second filling device. This makes it possible that, for example, in the first filling station, a partial filling and in the second filling station is a final filling of the capsules.
Gemäß einer weiteren bevorzugten Ausgestaltung der Erfindung ist die Bewegungsvorrichtung an der Füllvorrichtung angeordnet und die Füllvorrichtung wird relativ zum Kapselhalter bewegt. Hierdurch kann eine hohe Variabilität der Relativbewegung zwischen der Füllvorrichtung und dem Kapselhalter sichergestellt werden.According to a further preferred embodiment of the invention, the movement device is arranged on the filling device and the filling device is moved relative to the capsule holder. In this way, a high variability of the relative movement between the filling device and the capsule holder can be ensured.
Vorzugsweise umfasst die Bewegungsvorrichtung eine angetriebene Kurvenscheibe oder einen Linearmotor oder einen Servomotor. Hierdurch ist eine betriebssichere Bewegung der Bewegungsvorrichtung in radialer und vertikaler Richtung mit kurzen Taktzeiten möglich. Zwischen Motor und Füllvorrichtung kann alternativ ein Zwischengetriebe oder als Zwischenglied ein Schlitten kombiniert mit einer Koppel bzw. Umlenkung vorgesehen werden, um eine erzeugte vertikale Bewegung in eine horizontale Bewegung mittels Umlenkung umzuwandeln. Ferner kann hierzu auch ein Gewindetrieb (Zahnstange/Ritzel) eingesetzt werden. Alternativ kann der Antrieb auch unter der Maschinenebene bzw. Basisplatte der Station positioniert werden.Preferably, the moving device comprises a driven cam or a linear motor or a servomotor. As a result, a reliable movement of the moving device in the radial and vertical directions with short cycle times is possible. Alternatively, between the engine and filling device, an intermediate gear or as an intermediate member a carriage combined with a coupling or deflection can be provided to convert a generated vertical movement into a horizontal movement by means of deflection. Furthermore, this can also be a screw (rack / pinion) can be used. Alternatively, the drive can also be positioned below the machine level or base plate of the station.
Alternativ oder zusätzlich ist die Bewegungsvorrichtung am Kapselhalter angeordnet, um den Kapselhalter relativ zur Füllvorrichtung zu bewegen. Hierbei ist allerdings nachteilig, dass insbesondere bei Verwendung eines Stationsrades der Kapselhalter aus dem Stationsrad entnommen werden muss und relativ zur Füllvorrichtung bewegt werden muss.Alternatively or additionally, the movement device is arranged on the capsule holder in order to move the capsule holder relative to the filling device. In this case, however, it is disadvantageous that, in particular when using a station wheel, the capsule holder has to be removed from the station wheel and has to be moved relative to the filling device.
Weiterhin bevorzugt umfasst die Bewegungsvorrichtung ein Führungselement mit Kurvenbahn. Hierdurch wird mit minimierter Bauteileanzahl und kompaktem Bauvolumen eine betriebssichere radiale Bewegung der Kapselhalter erreicht.Further preferably, the movement device comprises a guide element with curved path. As a result, a reliable radial movement of the capsule holder is achieved with minimized number of components and compact volume.
Gemäß einer weiteren bevorzugten Ausführungsform der Erfindung ist ferner eine Kulissenführung vorgesehen, um den Kapselhalter in eine erste Stellung und eine zweite Stellung zu bringen. Dadurch wird eine radiale Bewegung der Kapselhalter während der Stillstandszeit der Vorrichtung ermöglicht. Somit kann nach dem Befüllen der in der erste Reihe der Aufnahmen befindlichen Kapseln auf einfache Weise eine Positionierung auf die zweite Reihe des Kapselhalters erfolgen und danach können alle darin befindlichen Kapseln nacheinander befüllt werden. Dadurch wird eine verbesserte Maschineneffizienz mit kürzeren Taktzeiten erreicht. Der Antrieb der Kulisse kann hierbei rein mechanisch oder über ein Kurvengetriebe mittels eines Linear- oder Servomotors erfolgen. Bei kleineren Leistungen ist alternativ auch der Einsatz eines pneumatischen Antriebs möglich.According to a further preferred embodiment of the invention, a slotted guide is further provided to bring the capsule holder in a first position and a second position. Thereby, a radial movement of the capsule holder during the downtime of the device is made possible. Thus, after filling the capsules located in the first row of recordings can be easily positioned on the second row of the capsule holder and then all capsules therein can be filled in succession. This achieves improved machine efficiency with shorter cycle times. The drive of the scenery can be done purely mechanically or via a cam mechanism by means of a linear or servo motor. For smaller outputs, the use of a pneumatic drive is also possible as an alternative.
Für einen schnellen Füllvorgang umfasst die Füllvorrichtung vorzugsweise mehrere Fülleinheiten, welche in Reihe angeordnet sind, um gleichzeitig mehrere Kapseln einer Reihe zu füllen. Besonders bevorzugt entspricht dabei eine Anzahl der Fülleinheiten einer Anzahl der Kapselaufnahmen in einer Reihe des Kapselhalters. Weiter bevorzugt ist die Füllvorrichtung eine Druck-Vakuum-Füllvorrichtung, wobei eine Füllmenge mittels Vakuum angesaugt wird und mittels Druck abgegeben wird.For a fast filling operation, the filling device preferably comprises a plurality of filling units, which are arranged in series, at the same time several To fill capsules in a row. Particularly preferably, a number of filling units corresponds to a number of capsule receptacles in a row of the capsule holder. More preferably, the filling device is a pressure-vacuum filling device, wherein a filling amount is sucked by means of vacuum and discharged by means of pressure.
Vorzugsweise umfasst die Füllvorrichtung eine flexible Produktzuführung, die zwischen Vorratsbehälter und Füllstation vorgesehen ist. Damit wird eine optimale Produktzuführung zu der sich bewegenden Füllstation ermöglicht. Für eine bessere Reinigung und um Einflüsse auf die Produkteigenschaften zu verhindern, ist es vorteilhaft, die Zuführung aus Stahl herzustellen und schwenkbar zu gestalten. Zwischen dem Vorratsbehälter bzw. der Füllstation und der schwenkbaren Produktzuführung sind jeweils flexible Dichtungen vorgesehen.Preferably, the filling device comprises a flexible product feed, which is provided between the reservoir and filling station. This enables optimal product feeding to the moving filling station. For better cleaning and to prevent influences on the product properties, it is advantageous to produce the steel feeder and to make it pivotable. Between the reservoir or the filling station and the pivotable product supply each flexible seals are provided.
Nachfolgend werden bevorzugte Ausführungsbeispiele der Erfindung unter Bezugnahme auf die begleitende Zeichnung im Detail beschrieben. In der Zeichnung ist:
Figur 1- eine schematische Draufsicht einer Vorrichtung zum Abfüllen von Füllgut gemäß einem ersten Ausführungsbeispiel der Erfindung,
Figur 2- eine schematische Schnittansicht durch eine
Füllvorrichtung von Figur 1 in einer ersten Position, Figur 3- eine schematische Schnittansicht durch eine
Füllvorrichtung von Figur 1 in einer zweiten Position, - Figur 4
- eine schematische Schnittansicht einer Bewegungsvorrichtung für die
Füllvorrichtung von Figur 2 und3 , - Figur 5
- eine schematische Schnittansicht einer alternativen Bewegungsvorrichtung für die
Füllvorrichtung von Figur 2 und3 , - Figur 6
- eine perspektivische Ansicht einer zweiten Ausführungsform einer Bewegungsvorrichtung samt Kulissenführung in einer ersten Stellung,
- Figur 7
- eine perspektivische Ansicht der Bewegungsvorrichtung von
Figur 6 in einer zweiten Stellung, Figur 8- eine vergrößerte Ansicht der Kulissenführung in der ersten Stellung von
Figur 6 , und - Figur 9
- eine vergrößerte Darstellung der Kulissenführung in der zweiten Stellung von
Figur 7 .
- FIG. 1
- a schematic plan view of an apparatus for filling of filling material according to a first embodiment of the invention,
- FIG. 2
- a schematic sectional view through a filling of
FIG. 1 in a first position, - FIG. 3
- a schematic sectional view through a filling of
FIG. 1 in a second position, - FIG. 4
- a schematic sectional view of a moving device for the filling of
FIG. 2 and3 . - FIG. 5
- a schematic sectional view of an alternative moving device for the filling of
FIG. 2 and3 . - FIG. 6
- 3 is a perspective view of a second embodiment of a movement device including link guide in a first position,
- FIG. 7
- a perspective view of the movement device of
FIG. 6 in a second position, - FIG. 8
- an enlarged view of the slotted guide in the first position of
FIG. 6 , and - FIG. 9
- an enlarged view of the slotted guide in the second position of
FIG. 7 ,
Nachfolgend wird unter Bezugnahme auf die
Die Stationen des Stationsrads 40 sind dabei wie folgt. An der Station 1 werden leere, geschlossene Kapseln, welche ein Kapselunterteil 23 und ein Kapseloberteil 24 umfassen, von einem Vorrat zugeführt. Die Kapseln werden dabei einzeln jeweils in eine Aufnahme 31 des Kapselhalters 30 eingeführt.The stations of the
An der Station 2 werden die Kapseln 22 geöffnet, d.h., das Kapseloberteil 24 wird vom Kapselunterteil 23 entfernt, so dass das Kapselunterteil 23 in der Aufnahme 31 verbleibt.At the
Es sei angemerkt, dass das Zuführen und Öffnen der Kapseln auch an der gleichen Station erfolgen kann. Auch kann z.B. an Station 1 die erste Reihe und an Station 2 die zweite Reihe mit Kapseln aufgefüllt werden, und an den Stationen vorzugsweise auch gleich geöffnet werden.It should be noted that the feeding and opening of the capsules can also take place at the same station. Also, e.g. at
Die Stationen 3 und 4 sind in diesem Ausführungsbeispiel nicht besetzt.The
Die Station 5 ist eine Füllstation, in welcher die geöffneten Kapseln 22 gefüllt werden. Hierzu ist eine Füllvorrichtung 25 vorgesehen, welche im Detail in den
Gegebenenfalls kann auch an der Station 6 noch eine weitere Füllvorrichtung vorgesehen sein, so dass beispielsweise die erste Füllvorrichtung an der Station 5 eine Teilfüllung vornimmt und die zweite Füllvorrichtung 6 eine abschließende Endbefüllung und genaue Dosierung der Füllmenge vornimmt.Optionally, a further filling device may also be provided at the station 6, so that, for example, the first filling device at the station 5 performs a partial filling and the second filling device 6 performs a final final filling and accurate metering of the filling quantity.
An der Station 7 kann beispielsweise eine Wiegevorrichtung vorgesehen sein, um die gefüllten Kapseln zu überprüfen.At the station 7, for example, a weighing device may be provided to check the filled capsules.
Die Station 8 ist eine Auswurfstation, bei der beschädigte oder nicht gefüllte oder falsch gefüllte Kapseln ausgesondert werden können.The
An der Station 9 werden die Kapseloberteile 24 wieder über die nun gefüllten Kapselunterteile 23 positioniert und in der Station 10 werden die Kapseln wieder verschlossen. Dies kann beispielsweise durch Absenken der Kapseloberteile auf die Kapselunterteile erfolgen.At the station 9, the capsule tops 24 are again positioned over the now filled
Die Station 11 ist die Abgabestation der gefüllten Kapseln und die Station 12 ist eine Reinigungsstation, in welcher die Kapselhalter 30 gereinigt werden, um Fehlbefüllungen bzw. falsches Aufnehmen der Kapseln in die Aufnahmen 31 zu vermeiden.The
Wie aus
Wie in
Wie aus
Demzufolge wird eine betriebssichere Bewegung der Bewegungsvorrichtung 50 bzw. 60 mit hoher Variabilität zwischen der Füllvorrichtung 25 und dem Kapselhalter 30 ermöglicht. Ferner wird dadurch eine rasche Befüllung der Kapseln mit deutlich verkürzten Taktzeiten gewährleistet. Zudem ist eine flexible Anpassung bzw. Integration der Bewegungsvorrichtung 50, 60 entsprechend den jeweiligen Platzverhältnissen am Stationsrad 40 der erfindungsgemäßen Vorrichtung 20 möglich.As a result, a reliable movement of the moving
Nachfolgend wird mit Bezug auf die
Im Gegensatz zum zuvor beschriebenen ersten Ausführungsbeispiel umfasst die Vorrichtung 20 bei diesem zweiten Ausführungsbeispiel eine Bewegungsvorrichtung 70, die am Stationsrad 40 angeordnet ist und eine Relativbewegung zwischen der Füllvorrichtung 25 und dem Kapselhalter 30 in radialer Richtung bzw. X-Richtung ausführt. Die Bewegungsvorrichtung 70 weist hierzu ein Führungselement 71 mit einer Kurvenbahn 72 auf. Ferner ist am Führungselement 71 eine Kulissenführung 73 mit einer darin ausgebildeten Ausnehmung 74 (vergl.
Bei der Rotationsbewegung A des Stationsrads 40 wird der Kapselhalter 30 entsprechend der Formgebung der Kurvenbahn 72 in radialer Richtung bzw. X-Richtung relativ zur hier nicht dargestellten Füllvorrichtung 25 bewegt. Die Kulissenführung 73 befindet sich dabei in einer in
Zur Befüllung der in einer benachbarten Reihe R2 befindlichen Kapselunterteilen 23 wird die Kulissenführung 73 im Stillstand des Stationsrads 40 von der ersten Stellung B in eine durch einen Pfeil dargestellte zweite Stellung C verschoben, die in
Es sei angemerkt, dass alternativ auch eine Kombination beider zuvor beschriebenen Bewegungsvorrichtungen möglich ist, sodass sowohl die Füllvorrichtung als auch der Kapselhalter bewegt werden können. Dadurch ist eine schnellere Positionierung der verwendeten Kapselhalter und der Füllstation möglich, wodurch im individuellen Anwendungsfall eine weitere Steigerung der Maschineneffizienz erreichbar ist. Allerdings wird dadurch auch der Maschinenaufwand vergrößert. Weiter sei angemerkt, dass die Füllvorrichtung 25 eine Füllzeit aufweist, welche die Hälfte einer Zeit einer Station mit der zweitkürzesten Bearbeitungszeit ist. Hierdurch ist es möglich, einen vorgegebenen Takt des Stationsrades 40 sehr gut einzuhalten, wobei insbesondere bei Verwendung von einer Füllvorrichtung mit fünf Fülleinheiten sowohl die erste Reihe R1 als auch die zweite Reihe R2 des Kapselhalters 30 in nur einer Station gefüllt werden können.It should be noted that, alternatively, a combination of both previously described moving devices is possible, so that both the filling device and the capsule holder can be moved. As a result, a faster positioning of the capsule holder used and the filling station is possible, whereby a further increase in machine efficiency can be achieved in an individual application. However, this also increases the machine outlay. Further, it should be noted that the filling
Die erfindungsgemäße Vorrichtung zum Abfüllen von Füllgut 21 in Kapseln 22 wird vorzugsweise zur Befüllung von Kapseln mit Medikamenten verwendet.The device according to the invention for filling
Claims (14)
- Device for introducing filling material (21) into capsules (22), said device including:- a filling device (25) for supplying filling material (21) to the capsules (22),- a capsule holder (30) with at least one row of accommodating means (31) in which the capsules (22) to be filled are arranged,- a station arrangement having several stations which are arranged one after the other, wherein the station arrangement includes at least one capsule filling station (5) and one drive which operates in a fixed cycle and- a movement apparatus (50; 60; 70) which carries out a relative movement between the filling device (25) and the capsule holder (30) at a capsule filling station (5),- wherein the filling device (25), in relation to the capsule holder (30), assumes at least one first filling position for filling a first capsule and one second filling position for filling a second capsule,
characterized in that
the capsule filling station (5) has a dosing wheel (26) and a hopper funnel (27) for accommodating the filling material (21). - Device according to Claim 1, characterized in that the station arrangement includes a station wheel (40) with a plurality of capsule holders (30) and the movement apparatus (50; 60; 70) carries out a relative movement between the filling device (25) and the capsule holder (30) in the radial direction (X).
- Device according to one of the preceding claims, characterized in that a relative movement between the filling device (25) and the capsule holder (30) in a first direction (X) and a second direction (Y) is possible in a horizontal plane, wherein the first direction (X) is perpendicular to the second direction (Y).
- Device according to Claim 1, characterized in that the dosing wheel (26) has at least one first filling chamber (28a) and one second filling chamber (28b) and during a movement operation the dosing wheel (26) is rotated from the first filling position to the second filling position in order to fill up one of the filling chambers (28a, 28b) with filling material.
- Device according to one of the preceding claims, characterized in that a fill time in the capsule filling station (5) is the shortest operating time in the case of all the individual operations of the respective stations of the station arrangement.
- Device according to one of the preceding claims, characterized in that the capsule holder (30) includes a first row (R1) of accommodating means (31) and a second row (R2) of accommodating means (31), wherein the first and second row are arranged parallel to each other.
- Device according to one of the preceding claims, characterized by a second capsule filling station (5) with a second filling device.
- Device according to one of the preceding claims, characterized in that the movement apparatus (50; 60) is arranged at the filling device (25) and moves the filling device (25) in relation to the capsule holder (30).
- Device according to Claim 8, characterized in that the movement apparatus (50, 60) includes a driven cam disk (50) or a linear motor or a servomotor.
- Device according to one of Claims 1 to 7, characterized in that the movement apparatus (70) is arranged at the capsule holder (30) and moves the capsule holder (30) in relation to the filling device (25).
- Device according to Claim 10, characterized in that the movement apparatus (70) includes a guiding element (71) with a curved path (72).
- Device according to Claim 11, additionally including a connecting link guide (73) in order to move the capsule holder (30) into a first position (B) and a second position (C).
- Device according to one of the preceding claims, characterized in that the filling device (25) includes several filling units in order to fill several capsules in the accommodating means (31) of a row (R1, R2) at the same time, wherein, in particular, the number of filling units corresponds to the number of accommodating means (31) in a row and wherein the filling device is, in particular, a pressure/vacuum filling device.
- Device according to one of the preceding claims, characterized in that the filling device (25) includes a flexible product supplying means (200).
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102010063138 | 2010-12-15 | ||
| DE102011084555A DE102011084555A1 (en) | 2010-12-15 | 2011-10-14 | Device for filling contents in capsules |
| PCT/EP2011/069395 WO2012079840A1 (en) | 2010-12-15 | 2011-11-04 | Device for introducing filling material into capsules |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP2651368A1 EP2651368A1 (en) | 2013-10-23 |
| EP2651368B1 true EP2651368B1 (en) | 2015-04-29 |
Family
ID=44906149
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP20110778626 Active EP2651368B1 (en) | 2010-12-15 | 2011-11-04 | Device for introducing filling material into capsules |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9549876B2 (en) |
| EP (1) | EP2651368B1 (en) |
| JP (1) | JP5774123B2 (en) |
| KR (1) | KR101843717B1 (en) |
| CN (1) | CN103260581B (en) |
| DE (1) | DE102011084555A1 (en) |
| WO (1) | WO2012079840A1 (en) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1392277B1 (en) * | 2008-12-18 | 2012-02-24 | Ima Spa | MACHINE AND METHOD TO FILL AND CHECK CAPSULES |
| DE102011085283B4 (en) * | 2011-02-21 | 2025-03-27 | Syntegon Technology Gmbh | Device for dosing powdered filling material |
| DE102013109471B8 (en) * | 2013-08-30 | 2015-02-19 | Fette Engineering GmbH | Device for filling and closing capsules |
| DE102013113446B4 (en) | 2013-12-04 | 2017-04-13 | Fette Engineering GmbH | Apparatus and method for filling capsules |
| DE102015206407A1 (en) * | 2015-04-10 | 2016-10-13 | Robert Bosch Gmbh | Device for dosing powdered product |
| DE102017204083A1 (en) * | 2017-03-13 | 2018-09-13 | Robert Bosch Gmbh | Device for filling filling material |
| EP3578157A1 (en) * | 2018-06-05 | 2019-12-11 | Harro Höfliger Verpackungsmaschinen GmbH | Capsule filling machine for filling capsules and cleaning unit for use in a capsule filling machine |
| EP3608233B1 (en) * | 2018-08-08 | 2020-10-21 | Harro Höfliger Verpackungsmaschinen GmbH | Dosing roll |
| IT201900013971A1 (en) * | 2019-08-05 | 2021-02-05 | Ima Spa | Machine for making capsules. |
| CN111449963A (en) * | 2020-05-13 | 2020-07-28 | 杭州赛飞自动化设备有限公司 | A Double Filling High Yield Capsule Filling Machine |
| KR102333883B1 (en) * | 2021-07-14 | 2021-12-03 | 주식회사 피티케이 | Device of providing power for capsule filler |
| CN115352690A (en) * | 2022-08-06 | 2022-11-18 | 扬州中惠制药有限公司 | Capsule production facility of pharmaceutical production usefulness |
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| US479812A (en) * | 1892-08-02 | Capsule-filling machine | ||
| US3656518A (en) * | 1967-03-27 | 1972-04-18 | Perry Ind Inc | Method and apparatus for measuring and dispensing predetermined equal amounts of powdered material |
| CA1259966A (en) | 1985-02-27 | 1989-09-26 | Taizo Yamamoto | Capsule filling apparatus |
| JPH07112878B2 (en) * | 1985-09-06 | 1995-12-06 | 第一製薬株式会社 | Capsule filling machine |
| JPH01232962A (en) * | 1988-03-11 | 1989-09-18 | Nippon Eranko Kk | capsule filling machine |
| JPH02180265A (en) * | 1988-12-28 | 1990-07-13 | Nippon Eranko Kk | Charging device into capsule |
| IT1245757B (en) | 1991-01-15 | 1994-10-14 | Mg 2 Spa | MACHINE FOR DOSING PHARMACEUTICAL PRODUCTS IN POWDER. |
| JP3315183B2 (en) | 1993-03-15 | 2002-08-19 | 株式会社東芝 | Turbine blade coupling device |
| NL9301843A (en) | 1993-10-25 | 1995-05-16 | Arie Greeve | Method and device for filling one or more capsules with medicament. |
| IT1278210B1 (en) | 1995-05-19 | 1997-11-17 | Ima Spa | AUTOMATIC MACHINE FOR PACKAGING TABLETS WITHIN JELLY CAPSULES |
| US5826633A (en) * | 1996-04-26 | 1998-10-27 | Inhale Therapeutic Systems | Powder filling systems, apparatus and methods |
| DE19915259A1 (en) | 1999-04-03 | 2000-10-05 | Bosch Gmbh Robert | Powder dispensing device comprises conveyor for e containers, feed chamber for powder and ceramic filler wheel |
| US6357490B1 (en) * | 2000-08-22 | 2002-03-19 | Advanced Inhalation Research, Inc. | System, method and apparatus for filling containers |
| BR0212003B1 (en) | 2001-08-17 | 2013-11-12 | APPARATUS AND PROCESS FOR FILLING SPACES BETWEEN YOURS WITH PRIVATE MATERIAL AND APPARATUS, PROCESS AND SYSTEM FOR FILLING AT LEAST ONE CAVITY IN A ITEM WITH GRANULAR OR PARTICULAR MATERIAL | |
| ITBO20020284A1 (en) | 2002-05-14 | 2003-11-14 | Ima Spa | OPERATING MACHINE |
| US20040081689A1 (en) | 2002-10-24 | 2004-04-29 | Dunfield John Stephen | Pharmaceutical dosage form and method of making |
| US7134459B2 (en) * | 2003-06-12 | 2006-11-14 | Symyx Technologies, Inc. | Methods and apparatus for mixing powdered samples |
| DE102005016124A1 (en) * | 2005-04-08 | 2006-10-12 | Robert Bosch Gmbh | Sensor device of a packaging machine |
| US20090050446A1 (en) * | 2005-07-15 | 2009-02-26 | Mike Cliff | Method for transporting a particulate material and a transportation device for a particulate material |
| DE102005039765A1 (en) | 2005-08-23 | 2007-03-01 | Robert Bosch Gmbh | sensing device |
| JP4989494B2 (en) * | 2006-02-06 | 2012-08-01 | 株式会社モリモト医薬 | Powder filling equipment |
| CN201098365Y (en) * | 2007-10-22 | 2008-08-13 | 湖南千山制药机械股份有限公司 | Device for quantitatively filling tablet into capsule |
| EP2100581A1 (en) * | 2008-03-12 | 2009-09-16 | MG2 S.r.l | Machine for filling containers with at least one powdered product |
| JP5227708B2 (en) * | 2008-09-18 | 2013-07-03 | 株式会社ミューチュアル | Powder distribution apparatus and distribution method |
| IT1390803B1 (en) * | 2008-09-30 | 2011-10-19 | Mg2 Srl | EQUIPMENT FOR DOSING PULVERULATING OR GRANULAR MATERIALS IN CAPSULES OR SIMILAR |
| IT1397691B1 (en) * | 2009-12-22 | 2013-01-24 | Mg 2 Srl | INTERMITTENT ROTARY MACHINE FOR FILLING CAPSULES WITH PHARMACEUTICALS. |
-
2011
- 2011-10-14 DE DE102011084555A patent/DE102011084555A1/en not_active Withdrawn
- 2011-11-04 KR KR1020137015330A patent/KR101843717B1/en active Active
- 2011-11-04 WO PCT/EP2011/069395 patent/WO2012079840A1/en not_active Ceased
- 2011-11-04 JP JP2013543592A patent/JP5774123B2/en active Active
- 2011-11-04 CN CN201180059868.3A patent/CN103260581B/en active Active
- 2011-11-04 EP EP20110778626 patent/EP2651368B1/en active Active
- 2011-11-04 US US13/992,960 patent/US9549876B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2014501673A (en) | 2014-01-23 |
| KR20130140076A (en) | 2013-12-23 |
| US20130255833A1 (en) | 2013-10-03 |
| US9549876B2 (en) | 2017-01-24 |
| CN103260581A (en) | 2013-08-21 |
| KR101843717B1 (en) | 2018-03-30 |
| DE102011084555A1 (en) | 2012-06-21 |
| CN103260581B (en) | 2015-08-26 |
| WO2012079840A1 (en) | 2012-06-21 |
| EP2651368A1 (en) | 2013-10-23 |
| JP5774123B2 (en) | 2015-09-02 |
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