[go: up one dir, main page]

EP2430973A4 - Dispositif de diagnostic d'image de flux sanguin - Google Patents

Dispositif de diagnostic d'image de flux sanguin

Info

Publication number
EP2430973A4
EP2430973A4 EP10774808.9A EP10774808A EP2430973A4 EP 2430973 A4 EP2430973 A4 EP 2430973A4 EP 10774808 A EP10774808 A EP 10774808A EP 2430973 A4 EP2430973 A4 EP 2430973A4
Authority
EP
European Patent Office
Prior art keywords
blood flow
flow image
diagnosing blood
diagnosing
image
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP10774808.9A
Other languages
German (de)
English (en)
Other versions
EP2430973A1 (fr
EP2430973B1 (fr
Inventor
Hitoshi Fujii
Kenji Okamoto
Noriyoshi Takahashi
Hiroyuki Ishihara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyushu Institute of Technology NUC
Original Assignee
Kyushu Institute of Technology NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyushu Institute of Technology NUC filed Critical Kyushu Institute of Technology NUC
Publication of EP2430973A1 publication Critical patent/EP2430973A1/fr
Publication of EP2430973A4 publication Critical patent/EP2430973A4/fr
Application granted granted Critical
Publication of EP2430973B1 publication Critical patent/EP2430973B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/026Measuring blood flow
    • A61B5/0261Measuring blood flow using optical means, e.g. infrared light
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/12Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes
    • A61B3/1225Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes using coherent radiation
    • A61B3/1233Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes using coherent radiation for measuring blood flow, e.g. at the retina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/02007Evaluating blood vessel condition, e.g. elasticity, compliance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4887Locating particular structures in or on the body
    • A61B5/489Blood vessels

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Pathology (AREA)
  • Vascular Medicine (AREA)
  • Physiology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Eye Examination Apparatus (AREA)
EP10774808.9A 2009-05-13 2010-04-20 Dispositif de diagnostic d'image de flux sanguin Active EP2430973B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2009116050 2009-05-13
JP2009246274 2009-10-27
PCT/JP2010/056980 WO2010131550A1 (fr) 2009-05-13 2010-04-20 Dispositif de diagnostic d'image de flux sanguin

Publications (3)

Publication Number Publication Date
EP2430973A1 EP2430973A1 (fr) 2012-03-21
EP2430973A4 true EP2430973A4 (fr) 2014-01-22
EP2430973B1 EP2430973B1 (fr) 2014-09-17

Family

ID=43084927

Family Applications (1)

Application Number Title Priority Date Filing Date
EP10774808.9A Active EP2430973B1 (fr) 2009-05-13 2010-04-20 Dispositif de diagnostic d'image de flux sanguin

Country Status (4)

Country Link
US (1) US9028421B2 (fr)
EP (1) EP2430973B1 (fr)
JP (1) JP5578735B2 (fr)
WO (1) WO2010131550A1 (fr)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8838210B2 (en) * 2006-06-29 2014-09-16 AccuView, Inc. Scanned laser vein contrast enhancer using a single laser
EP2663222B1 (fr) 2011-01-10 2021-10-27 East Carolina University Procédés et systèmes pour une détermination non effractive de distribution du flux sanguin à l'aide de techniques d'imagerie à tachetures et modélisation hémodynamique
US9226673B2 (en) 2011-01-10 2016-01-05 East Carolina University Methods, systems and computer program products for non-invasive determination of blood flow distribution using speckle imaging techniques and hemodynamic modeling
EP2665406B1 (fr) * 2011-01-20 2021-03-10 University of Iowa Research Foundation Détermination automatisée de rapport artérioveineux dans des images de vaisseaux sanguins
US9986909B2 (en) * 2011-02-25 2018-06-05 Canon Kabushiki Kaisha Image processing apparatus and image processing system for displaying information about ocular blood flow
JP5792967B2 (ja) * 2011-02-25 2015-10-14 キヤノン株式会社 画像処理装置及び画像処理システム
JP5867720B2 (ja) * 2012-03-29 2016-02-24 株式会社トプコン 画像表示装置、画像表示方法、及びプログラム
EP3127474B1 (fr) * 2012-03-12 2021-11-10 Kabushiki Kaisha Topcon Appareil d'affichage d'image et procédé d'affichage d'image
JP5833228B2 (ja) * 2012-04-20 2015-12-16 パイオニア株式会社 血圧推定装置及び方法
US20130324810A1 (en) * 2012-06-01 2013-12-05 Yuri Gelland Cerebral and Retinal Perfusion Monitoring Systems and Devices
WO2014084398A1 (fr) 2012-11-30 2014-06-05 株式会社 東芝 Dispositif d'évaluation de diagnostic d'image médicale
JP6491378B2 (ja) * 2012-11-30 2019-03-27 キヤノンメディカルシステムズ株式会社 表示方法、医用画像診断装置、及びプログラム
JP6062793B2 (ja) * 2013-04-23 2017-01-18 ソフトケア有限会社 血流画像診断装置
US9462954B2 (en) * 2013-09-04 2016-10-11 Siemens Aktiengesellschaft Method and system for blood flow velocity reconstruction from medical images
EP3166480A4 (fr) * 2014-07-08 2018-02-14 Scinovia, Corp. Déterminations de débit de fluide à l'aide de cartes de vecteur de vitesse
CA2963866C (fr) * 2014-10-14 2023-11-07 East Carolina University Procedes, systemes et produits de programme informatique pour determiner des parametres d'etat hemodynamique au moyen de signaux derives d'imagerie multispectrale de circulation e t perfusion sanguine
US11553844B2 (en) 2014-10-14 2023-01-17 East Carolina University Methods, systems and computer program products for calculating MetaKG signals for regions having multiple sets of optical characteristics
EP3188651A4 (fr) 2014-10-14 2018-07-04 East Carolina University Procédés, systèmes et produits-programmes informatique pour visualiser des structures anatomiques, un débit sanguin et une physiologie de perfusion à l'aide de techniques d'imagerie
JP6507639B2 (ja) * 2014-12-29 2019-05-08 花王株式会社 皮膚血流量の計測方法
US10070796B2 (en) 2015-02-04 2018-09-11 General Electric Company Systems and methods for quantitative microcirculation state monitoring
JP6562644B2 (ja) * 2015-02-06 2019-08-21 キヤノン株式会社 眼科装置及びその制御方法、並びに、プログラム
US10390718B2 (en) 2015-03-20 2019-08-27 East Carolina University Multi-spectral physiologic visualization (MSPV) using laser imaging methods and systems for blood flow and perfusion imaging and quantification in an endoscopic design
US10058256B2 (en) 2015-03-20 2018-08-28 East Carolina University Multi-spectral laser imaging (MSLI) methods and systems for blood flow and perfusion imaging and quantification
JP6538613B2 (ja) * 2015-06-08 2019-07-03 株式会社トーメーコーポレーション 速度測定装置、速度測定プログラムおよび速度測定方法
WO2017038729A1 (fr) * 2015-09-01 2017-03-09 コスモテック株式会社 Méthode d'évaluation de l'état de la circulation sanguine, dispositif de mesure du débit sanguin, et système de mesure du débit sanguin
US20180344176A1 (en) * 2015-12-04 2018-12-06 Sony Corporation Information processing apparatus, speckle imaging system, and information processing method
WO2018011411A1 (fr) * 2016-07-14 2018-01-18 Koninklijke Philips N.V. Appareil, système et procédé pour retour d'informations sur la qualité de mesure de propriété dans un vaisseau
JP6747130B2 (ja) * 2016-07-20 2020-08-26 大日本印刷株式会社 眼底画像処理装置
RU2648029C2 (ru) * 2016-08-10 2018-03-21 Самсунг Электроникс Ко., Лтд. Устройство и способ измерения кровяного давления
US10872410B2 (en) * 2016-09-29 2020-12-22 Animantis, Llc Methods and apparatus for assessing immune system activity and therapeutic efficacy
DE102016219607B4 (de) * 2016-10-10 2025-04-30 Siemens Healthineers Ag Erzeugung einer mit anatomischen Bilddaten korrelierten Ergebniskarte
JP6995485B2 (ja) * 2017-03-03 2022-01-14 キヤノン株式会社 眼科装置、装置の制御方法及びプログラム
CN109247910B (zh) * 2017-07-12 2020-12-15 京东方科技集团股份有限公司 血管显示设备以及血管显示方法
US11116414B2 (en) * 2017-08-16 2021-09-14 Seiko Epson Corporation Biological analysis device, biological analysis method, and program
US11253205B2 (en) 2017-08-16 2022-02-22 Seiko Epson Corporation Pulse pressure and blood pressure analysis device, pulse pressure and blood pressure analysis method, and program
US11317873B2 (en) * 2017-08-16 2022-05-03 Seiko Epson Corporation Biological analysis device, biological analysis method, and program
JP2019055134A (ja) * 2017-09-22 2019-04-11 株式会社トプコン 眼科撮影装置及び眼科情報処理装置
CN109239014B (zh) * 2018-09-05 2021-04-02 西北核技术研究所 一种用于图像位置校准的特征点获取方法
JP2020103714A (ja) * 2018-12-28 2020-07-09 株式会社トプコン 血流計測装置、その制御方法、プログラム、及び記録媒体
JP2023509772A (ja) 2020-01-08 2023-03-09 アクティブ サージカル, インコーポレイテッド レーザスペックル力フィードバックの推定
IL295510B2 (en) * 2020-02-14 2025-08-01 Activ Surgical Inc Systems and methods for processing laser speckle signals
JP7479030B2 (ja) * 2020-06-11 2024-05-08 国立大学法人旭川医科大学 血流解析装置、血流解析方法、及びプログラム
US11963683B2 (en) * 2020-10-02 2024-04-23 Cilag Gmbh International Method for operating tiered operation modes in a surgical system
USD1064287S1 (en) 2022-03-14 2025-02-25 O/D Vision Inc. Consumer electronics device
US12285243B2 (en) 2022-03-14 2025-04-29 O/D Vision Inc. Multi sensor handheld medical diagnostic device
US12381009B2 (en) 2022-03-14 2025-08-05 O/D Vision Inc. Systems and methods for artificial intelligence based standard of care support
US12380735B2 (en) 2022-03-14 2025-08-05 O/D Vision Inc. Systems and methods for biometric identification using patterns and blood flow characteristics of the outer eye
US12293837B2 (en) 2022-03-14 2025-05-06 O/D Vision Inc. Systems and methods for artificial intelligence based warning of potential health concerns
US12257025B2 (en) 2022-03-14 2025-03-25 O/D Vision Inc. AI enabled multisensor connected telehealth system
CN115760799B (zh) * 2022-11-23 2025-07-25 苏州微清医疗器械有限公司 一种视网膜血液流速测定方法及系统
WO2025231347A1 (fr) * 2024-05-03 2025-11-06 Topcon Corporation Vélocimétrie de granulation cohérente de tomographie par cohérence optique

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5116116A (en) * 1989-03-06 1992-05-26 Kowa Company Ltd. Ophthalmological diagnosis method
US5620000A (en) * 1993-07-02 1997-04-15 Heidelberg Engineering, Optische Messsysteme Gmbh Method and apparatus for measuring flow rate, particularly of blood
US20030088165A1 (en) * 2001-08-14 2003-05-08 University Of Alabama In Huntsville Multispectral image processing method, apparatus and computer program product for determining the blood oxygen saturation in a vessel
GB2454370A (en) * 2006-06-07 2009-05-06 Kyushu Inst Technology Personal authentication method and personal authentication device that use eye fundus blood flow measurement by laser light

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01124437A (ja) 1987-11-07 1989-05-17 Hitoshi Fujii 血流モニタ装置
AU608807B2 (en) * 1987-03-03 1991-04-18 Hitoshi Fujii Apparatus for monitoring bloodstream
JPS63214238A (ja) 1987-03-03 1988-09-06 藤居 良子 血流分布表示装置
EP0386927B1 (fr) * 1989-03-06 1994-08-03 Kowa Company Ltd. Dispositif de diagnostic ophtalmologique
EP0392744B1 (fr) * 1989-04-10 1995-03-01 Kowa Company Ltd. Méthode de mesure ophtalmologique et appareil
JP2749115B2 (ja) * 1989-04-17 1998-05-13 興和株式会社 眼科診断装置
JP2813899B2 (ja) 1989-09-26 1998-10-22 仁 藤居 眼科測定装置
US5150292A (en) * 1989-10-27 1992-09-22 Arch Development Corporation Method and system for determination of instantaneous and average blood flow rates from digital angiograms
JPH0428348A (ja) * 1990-05-24 1992-01-30 Hitoshi Fujii 血流状態画像化装置
US5640963A (en) * 1993-12-03 1997-06-24 Canon Kabushiki Kaisha Eye fundus blood flow meter
JP3332535B2 (ja) * 1993-12-14 2002-10-07 キヤノン株式会社 眼科測定装置
JPH08112262A (ja) 1994-10-19 1996-05-07 Hitoshi Fujii 血流計
US5954658A (en) * 1997-03-21 1999-09-21 Gorti; Sridhar Method and apparatus for measuring blood flow at precise depths in tissue and skin
IL124814A (en) * 1998-06-08 2003-04-10 Grinvald Amiram System and method for imaging and analysis of the movement of individual red blood corpuscles
JP2000037351A (ja) 1998-07-23 2000-02-08 Canon Inc 眼底検査装置
US6569104B2 (en) 1998-07-16 2003-05-27 Canon Kabushiki Kaisha Blood vessel detecting apparatus
EP1302163B1 (fr) * 2001-10-16 2006-07-05 Kabushiki Kaisha Toshiba Dispositif pour le calcul d'un indice des débits sanguins locaux
JP2003164431A (ja) 2001-11-30 2003-06-10 Hitoshi Fujii 血流速度測定装置
JP3855024B2 (ja) 2001-12-13 2006-12-06 国立大学法人九州工業大学 血流速度測定装置
WO2005122896A1 (fr) * 2004-06-18 2005-12-29 Kyushu Institute Of Technology Méthode d’identification personnelle par mesure du flux sanguin sous-cutané et dispositif d’identification personnelle
JP2006095350A (ja) * 2004-09-28 2006-04-13 Tamura Kaken Co Ltd 昇華物質回収方法および装置
JP4102888B2 (ja) * 2004-10-28 2008-06-18 国立大学法人九州工業大学 広視野角眼底血流画像化装置
US20090177098A1 (en) * 2006-01-16 2009-07-09 Kousuke Yakubo Examination System and Examination Method
WO2007097129A1 (fr) * 2006-02-22 2007-08-30 Kyushu Institute Of Technology Procede d'authentification de personne et dispositif d'authentification de personne utilisant la mesure du flux sanguin a l'extremite d'un doigt par un rayon laser
EP2079363B1 (fr) * 2006-10-30 2020-06-10 Elfi-Tech Ltd Procédé de mesure in vivo de paramètres biologiques
US20100056936A1 (en) * 2006-12-01 2010-03-04 Hitoshi Fujii Blood flow rate imaging device
JP2008237432A (ja) * 2007-03-27 2008-10-09 Kyushu Univ 眼底血流画像化装置
BRPI0810177A2 (pt) * 2007-04-10 2014-12-30 Univ Southern California Métodos e sistemas para medição de fluxo sanguíneo usando tomografia de coerência doppler
DE102008003978A1 (de) * 2008-01-11 2009-08-13 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Druckmesser, Blutdruckmesser, Verfahren zum Bestimmen von Druckwerten, Verfahren zum Kalibrieren eines Druckmessers und Computerprogramm

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5116116A (en) * 1989-03-06 1992-05-26 Kowa Company Ltd. Ophthalmological diagnosis method
US5620000A (en) * 1993-07-02 1997-04-15 Heidelberg Engineering, Optische Messsysteme Gmbh Method and apparatus for measuring flow rate, particularly of blood
US20030088165A1 (en) * 2001-08-14 2003-05-08 University Of Alabama In Huntsville Multispectral image processing method, apparatus and computer program product for determining the blood oxygen saturation in a vessel
GB2454370A (en) * 2006-06-07 2009-05-06 Kyushu Inst Technology Personal authentication method and personal authentication device that use eye fundus blood flow measurement by laser light

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
GORO WATANABE ET AL: "Imaging of choroidal hemodynamics in eyes with polypoidal choroidal vasculopathy using laser speckle phenomenon", JAPANESE JOURNAL OF OPHTHALMOLOGY ; THE OFFICIAL ENGLISH-LANGUAGE JOURNAL OF THE JAPANESE OPHTHALMOLOGICAL SOCIETY, SPRINGER-VERLAG, TO, vol. 52, no. 3, 27 July 2008 (2008-07-27), pages 175 - 181, XP019597640, ISSN: 1613-2246 *
LI N ET AL: "High spatiotemporal resolution imaging of the neurovascular response to electrical stimulation of rat peripheral trigeminal nerve as revealed by in vivo temporal laser speckle contrast", JOURNAL OF NEUROSCIENCE METHODS, ELSEVIER SCIENCE PUBLISHER B.V., AMSTERDAM, NL, vol. 176, no. 2, 30 January 2009 (2009-01-30), pages 230 - 236, XP025803774, ISSN: 0165-0270, [retrieved on 20080725], DOI: 10.1016/J.JNEUMETH.2008.07.013 *
See also references of WO2010131550A1 *

Also Published As

Publication number Publication date
WO2010131550A1 (fr) 2010-11-18
JP5578735B2 (ja) 2014-08-27
EP2430973A1 (fr) 2012-03-21
US9028421B2 (en) 2015-05-12
JPWO2010131550A1 (ja) 2012-11-01
US20110319775A1 (en) 2011-12-29
EP2430973B1 (fr) 2014-09-17

Similar Documents

Publication Publication Date Title
EP2430973A4 (fr) Dispositif de diagnostic d'image de flux sanguin
EP2281508A4 (fr) Dispositif de diagnostic à ultrasons
EP2126573A4 (fr) Dispositif de détection pour diagnostic
EP2119897A4 (fr) DISPOSITIF DE DIAGNOSTIC D'ANOMALIE POUR CAPTEUR DE NOx
EP2319417A4 (fr) Dispositif de diagnostic ultrasonique
EP2474266A4 (fr) Dispositif diagnostique à ultrasons
EP2296368A4 (fr) Dispositif d'imagerie
EP2347692A4 (fr) Dispositif d'imagerie
EP2508946A4 (fr) Dispositif d'imagerie stéréoscopique
EP2484288A4 (fr) Dispositif de diagnostic par imagerie
EP2564779A4 (fr) Dispositif de photographie d'image radiographique
EP2454998A4 (fr) Dispositif de diagnostic à ultrasons
EP1884197A4 (fr) Dispositif de diagnostic à imagerie
EP2783634A4 (fr) Dispositif de diagnostic de visualisation d'écoulement sanguin
EP2411793A4 (fr) Dispositif de détection d'un analyte
EP2624540A4 (fr) Dispositif d'imagerie
EP2626002A4 (fr) Dispositif d'imagerie
EP2251686A4 (fr) Dispositif d'examen ultrasonique
BRPI1012788A2 (pt) "sistema de diagnóstico"
EP2336821A4 (fr) Dispositif d'imagerie
EP1997434A4 (fr) Dispositif d'examen sanguin
EP2464113A4 (fr) Dispositif de génération d'images périphériques du véhicule
EP2347693A4 (fr) Dispositif d'endoscope
EP2491861A4 (fr) Système d'imagerie radiographique
EP2473636A4 (fr) Diagnostic d'interféron de type 1

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20111125

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20140102

RIC1 Information provided on ipc code assigned before grant

Ipc: A61B 3/10 20060101AFI20131217BHEP

Ipc: A61B 3/14 20060101ALI20131217BHEP

Ipc: A61B 3/12 20060101ALI20131217BHEP

Ipc: A61B 5/00 20060101ALI20131217BHEP

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

INTG Intention to grant announced

Effective date: 20140605

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: AT

Ref legal event code: REF

Ref document number: 687295

Country of ref document: AT

Kind code of ref document: T

Effective date: 20141015

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 602010019033

Country of ref document: DE

Effective date: 20141030

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20141217

Ref country code: SE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20140917

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20141218

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20140917

Ref country code: LT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20140917

REG Reference to a national code

Ref country code: NL

Ref legal event code: VDEP

Effective date: 20140917

REG Reference to a national code

Ref country code: LT

Ref legal event code: MG4D

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20140917

Ref country code: LV

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20140917

Ref country code: HR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20140917

REG Reference to a national code

Ref country code: AT

Ref legal event code: MK05

Ref document number: 687295

Country of ref document: AT

Kind code of ref document: T

Effective date: 20140917

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20140917

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: ES

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20140917

Ref country code: EE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20140917

Ref country code: CZ

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20140917

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20140917

Ref country code: PT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150119

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150117

Ref country code: RO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20140917

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: AT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20140917

Ref country code: PL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20140917

REG Reference to a national code

Ref country code: DE

Ref legal event code: R097

Ref document number: 602010019033

Country of ref document: DE

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20140917

26N No opposition filed

Effective date: 20150618

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20140917

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LU

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150420

Ref country code: SI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20140917

Ref country code: MC

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20140917

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

REG Reference to a national code

Ref country code: IE

Ref legal event code: MM4A

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20150430

Ref country code: CH

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20150430

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 7

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20150420

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20140917

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 8

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BG

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20140917

Ref country code: SM

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20140917

Ref country code: HU

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT; INVALID AB INITIO

Effective date: 20100420

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: TR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20140917

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20140917

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 9

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20140917

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: FR

Payment date: 20250310

Year of fee payment: 16

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 20250227

Year of fee payment: 16

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: DE

Payment date: 20250305

Year of fee payment: 16