EP2310510A4 - ADNI VACCINES AND METHODS FOR USE THEREOF - Google Patents

ADNI VACCINES AND METHODS FOR USE THEREOF

Info

Publication number: EP2310510A4
Authority: EP; European Patent Office
Prior art keywords: adni; vaccines; methods; adni vaccines
Prior art date: 2008-07-17
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

EP09798313A

Other languages

German (de)

French (fr)

Other versions

EP2310510A2 (en

EP2310510B1 (en

Inventor

Peter Pushko

Igor Lukashevich

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Medigen Inc

Original Assignee

Medigen Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-07-17

Filing date

2009-07-17

Publication date

2012-01-25

2009-07-17 Application filed by Medigen Inc filed Critical Medigen Inc

2009-07-17 Priority to EP21192928.6A priority Critical patent/EP3992296A1/en

2009-07-17 Priority to EP15166439.8A priority patent/EP2977457B1/en

2009-07-17 Priority to DK15166439.8T priority patent/DK2977457T3/en

2011-04-20 Publication of EP2310510A2 publication Critical patent/EP2310510A2/en

2012-01-25 Publication of EP2310510A4 publication Critical patent/EP2310510A4/en

2015-05-06 Application granted granted Critical

2015-05-06 Publication of EP2310510B1 publication Critical patent/EP2310510B1/en

Status Active legal-status Critical Current

2029-07-17 Anticipated expiration legal-status Critical

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/193—Equine encephalomyelitis virus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24161—Methods of inactivation or attenuation
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/36011—Togaviridae
- C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
- C12N2770/36134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/36011—Togaviridae
- C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
- C12N2770/36161—Methods of inactivation or attenuation
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Virology (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Immunology (AREA)
Microbiology (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Biochemistry (AREA)
Mycology (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Plant Pathology (AREA)
Physics & Mathematics (AREA)
Biophysics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

EP09798313.4A 2008-07-17 2009-07-17 Idna vaccines and methods for using the same Active EP2310510B1 (en)

Priority Applications (3)

Application Number	Priority Date	Filing Date	Title
EP21192928.6A EP3992296A1 (en)	2008-07-17	2009-07-17	Idna vaccines and methods for using the same
EP15166439.8A EP2977457B1 (en)	2008-07-17	2009-07-17	Idna vaccines and methods for using the same
DK15166439.8T DK2977457T3 (en)	2008-07-17	2009-07-17	IDNA VACCINES AND METHODS FOR USING THESE

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US8148208P	2008-07-17	2008-07-17
PCT/US2009/004133 WO2010008576A2 (en)	2008-07-17	2009-07-17	Idna vaccines and methods for using the same

Related Child Applications (2)

Application Number	Title	Priority Date	Filing Date
EP15166439.8A Division EP2977457B1 (en)	2008-07-17	2009-07-17	Idna vaccines and methods for using the same
EP21192928.6A Division EP3992296A1 (en)	2008-07-17	2009-07-17	Idna vaccines and methods for using the same

Publications (3)

Publication Number	Publication Date
EP2310510A2 EP2310510A2 (en)	2011-04-20
EP2310510A4 true EP2310510A4 (en)	2012-01-25
EP2310510B1 EP2310510B1 (en)	2015-05-06

Family

ID=41550920

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
EP21192928.6A Pending EP3992296A1 (en)	2008-07-17	2009-07-17	Idna vaccines and methods for using the same
EP09798313.4A Active EP2310510B1 (en)	2008-07-17	2009-07-17	Idna vaccines and methods for using the same
EP15166439.8A Active EP2977457B1 (en)	2008-07-17	2009-07-17	Idna vaccines and methods for using the same

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
EP21192928.6A Pending EP3992296A1 (en)	2008-07-17	2009-07-17	Idna vaccines and methods for using the same

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
EP15166439.8A Active EP2977457B1 (en)	2008-07-17	2009-07-17	Idna vaccines and methods for using the same

Country Status (6)

Country	Link
US (3)	US8691563B2 (en)
EP (3)	EP3992296A1 (en)
BR (1)	BRPI0916186B8 (en)
DK (2)	DK2310510T3 (en)
ES (2)	ES2902787T3 (en)
WO (1)	WO2010008576A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2902787T3 (en)	2008-07-17	2022-03-29	Medigen Inc	DNAi vaccines and procedures for using the same
US10602508B2 (en) *	2015-08-10	2020-03-24	Qualcomm Incorporated	LTE-direct communication for vehicle-to-vehicle
JP2020518648A (en)	2017-05-08	2020-06-25	グリットストーンオンコロジーインコーポレイテッド	Alphavirus neonatal antigen vector
BR112020013679A2 (en)	2018-01-04	2020-12-01	Iconic Therapeutics, Inc.	antitecid factor antibodies, antibody-drug conjugates and related methods
AU2020282369A1 (en)	2019-05-30	2022-01-20	Seattle Project Corp.	Modified adenoviruses
WO2022032196A2 (en)	2020-08-06	2022-02-10	Gritstone Bio, Inc.	Multiepitope vaccine cassettes

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20050276816A1 (en) *	2004-02-25	2005-12-15	University Of Kansas	Infectious DNA as a vaccine against west nile and other flavivirues

Family Cites Families (11)

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BRPI9701774B8 (en) *	1997-04-11	2015-09-29	Fundação Oswaldo Cruz Fiocruz	mutant and infectious yellow fever virus cdna, DNA construct, recombinant yellow fever virus and human vaccine against yellow fever infections.
US6565853B1 (en) *	1998-03-27	2003-05-20	The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland	Recombinant virus
FR2779736B1 (en) *	1998-06-12	2002-12-13	Goemar Lab Sa	GENES CODING BETA-AGARASES AND THEIR USE FOR THE PRODUCTION OF AGARS BIODEGRADATION ENZYMES
AU771774B2 (en) *	1998-12-07	2004-04-01	U.S. Medical Research Institute Of Infectious Diseases	Live attenuated Venezuelan equine encephalitis vaccine
GB2372991B (en)	2001-03-09	2004-11-17	Fiocruz Fundacao Oswaldo Cruz	Flavivirus expression vector
JP4608210B2 (en) *	2001-05-31	2011-01-12	ノバルティスバクシンズアンドダイアグノスティックス，インコーポレーテッド	Chimeric alphavirus replicon particles
AU2003902842A0 (en) *	2003-06-06	2003-06-26	The University Of Queensland	Flavivirus replicon packaging system
WO2005026316A2 (en) *	2003-09-15	2005-03-24	Bioption Ab	Alphavirus vaccines
US20060198854A1 (en)	2004-12-28	2006-09-07	Peter Pushko	Vector platforms derived from the alphavirus vaccines
ES2902787T3 (en) *	2008-07-17	2022-03-29	Medigen Inc	DNAi vaccines and procedures for using the same
US9101572B2 (en) *	2009-12-31	2015-08-11	Medigen, Inc.	Infectious DNA vaccines against chikungunya virus

2009
- 2009-07-17 ES ES15166439T patent/ES2902787T3/en active Active
- 2009-07-17 EP EP21192928.6A patent/EP3992296A1/en active Pending
- 2009-07-17 DK DK09798313.4T patent/DK2310510T3/en active
- 2009-07-17 US US13/054,372 patent/US8691563B2/en active Active - Reinstated
- 2009-07-17 DK DK15166439.8T patent/DK2977457T3/en active
- 2009-07-17 WO PCT/US2009/004133 patent/WO2010008576A2/en not_active Ceased
- 2009-07-17 BR BRPI0916186A patent/BRPI0916186B8/en active IP Right Grant
- 2009-07-17 ES ES09798313.4T patent/ES2544702T3/en active Active
- 2009-07-17 EP EP09798313.4A patent/EP2310510B1/en active Active
- 2009-07-17 EP EP15166439.8A patent/EP2977457B1/en active Active
2014
- 2014-01-30 US US14/168,788 patent/US9968672B2/en active Active
2018
- 2018-04-19 US US15/957,550 patent/US10653769B2/en active Active

Patent Citations (1)

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US20050276816A1 (en) *	2004-02-25	2005-12-15	University Of Kansas	Infectious DNA as a vaccine against west nile and other flavivirues

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
QUEREC TROY ET AL: "Yellow fever vaccine YF-17D activates multiple dendritic cell subsets via TLR2, 7, 8, and 9 to stimulate polyvalent immunity", February 2006, JOURNAL OF EXPERIMENTAL MEDICINE, VOL. 203, NR. 2, PAGE(S) 413-424, ISSN: 0022-1007, XP002665595 *
See also references of WO2010008576A2 *

Also Published As

Publication number	Publication date
ES2902787T3 (en)	2022-03-29
WO2010008576A2 (en)	2010-01-21
US9968672B2 (en)	2018-05-15
EP2310510A2 (en)	2011-04-20
EP3992296A1 (en)	2022-05-04
EP2977457B1 (en)	2021-09-01
BRPI0916186A2 (en)	2018-05-29
EP2977457A3 (en)	2016-05-04
WO2010008576A3 (en)	2010-04-29
EP2977457A2 (en)	2016-01-27
EP2310510B1 (en)	2015-05-06
US20140178430A1 (en)	2014-06-26
US8691563B2 (en)	2014-04-08
US10653769B2 (en)	2020-05-19
US20180243404A1 (en)	2018-08-30
ES2544702T3 (en)	2015-09-02
HK1220720A1 (en)	2017-05-12
DK2310510T3 (en)	2015-08-03
BRPI0916186B8 (en)	2021-05-25
DK2977457T3 (en)	2021-12-06
BRPI0916186B1 (en)	2021-03-09
US20110243989A1 (en)	2011-10-06

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Legal Events

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2011-03-18	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
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2011-10-26	DAX	Request for extension of the european patent (deleted)
2012-01-18	RIC1	Information provided on ipc code assigned before grant	Ipc: C12N 15/85 20060101ALI20111214BHEP Ipc: C12N 5/00 20060101ALI20111214BHEP Ipc: A61K 48/00 20060101ALI20111214BHEP Ipc: C12N 15/65 20060101AFI20111214BHEP
2012-01-25	A4	Supplementary search report drawn up and despatched	Effective date: 20111222
2012-06-13	RIC1	Information provided on ipc code assigned before grant	Ipc: A61K 48/00 20060101ALI20120509BHEP Ipc: C12N 5/00 20060101ALI20120509BHEP Ipc: C12N 15/85 20060101ALI20120509BHEP Ipc: C12N 15/65 20060101AFI20120509BHEP
2013-01-16	17Q	First examination report despatched	Effective date: 20121221
2014-10-29	RIC1	Information provided on ipc code assigned before grant	Ipc: A61K 39/12 20060101ALI20140924BHEP Ipc: C12N 15/85 20060101ALI20140924BHEP Ipc: C12N 15/65 20060101AFI20140924BHEP Ipc: C12N 5/00 20060101ALI20140924BHEP Ipc: A61K 48/00 20060101ALI20140924BHEP
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