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EP2307016A4 - PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OSTEOPOROSIS COMPRISING A BENZAMIDINE DERIVATIVE OR A SALT THEREOF, AND BISPHOSPHONATE - Google Patents

PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OSTEOPOROSIS COMPRISING A BENZAMIDINE DERIVATIVE OR A SALT THEREOF, AND BISPHOSPHONATE

Info

Publication number
EP2307016A4
EP2307016A4 EP09803180A EP09803180A EP2307016A4 EP 2307016 A4 EP2307016 A4 EP 2307016A4 EP 09803180 A EP09803180 A EP 09803180A EP 09803180 A EP09803180 A EP 09803180A EP 2307016 A4 EP2307016 A4 EP 2307016A4
Authority
EP
European Patent Office
Prior art keywords
bisphosphonate
salt
preventing
pharmaceutical composition
treating osteoporosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP09803180A
Other languages
German (de)
French (fr)
Other versions
EP2307016A2 (en
Inventor
Jin Soo Lee
Yun Ha Hwang
Jei Man Ryu
Young Goo Jin
Ki Yoon Kim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dong Wha Pharm Co Ltd
Original Assignee
Dong Wha Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dong Wha Pharm Co Ltd filed Critical Dong Wha Pharm Co Ltd
Publication of EP2307016A2 publication Critical patent/EP2307016A2/en
Publication of EP2307016A4 publication Critical patent/EP2307016A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
EP09803180A 2008-08-01 2009-07-31 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OSTEOPOROSIS COMPRISING A BENZAMIDINE DERIVATIVE OR A SALT THEREOF, AND BISPHOSPHONATE Withdrawn EP2307016A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20080075791 2008-08-01
KR1020090007774A KR20100014090A (en) 2008-08-01 2009-01-31 A pharmaceutical composition for preventing or treating osteoporosis comprising benzamidine derivative or its salt, and bisphosphonate
PCT/KR2009/004295 WO2010013975A2 (en) 2008-08-01 2009-07-31 A pharmaceutical composition for preventing or treating osteoporosis comprising benzamidine derivative or its salt, and bisphosphonate

Publications (2)

Publication Number Publication Date
EP2307016A2 EP2307016A2 (en) 2011-04-13
EP2307016A4 true EP2307016A4 (en) 2011-12-28

Family

ID=42087985

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09803180A Withdrawn EP2307016A4 (en) 2008-08-01 2009-07-31 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OSTEOPOROSIS COMPRISING A BENZAMIDINE DERIVATIVE OR A SALT THEREOF, AND BISPHOSPHONATE

Country Status (6)

Country Link
EP (1) EP2307016A4 (en)
JP (1) JP2011529876A (en)
KR (2) KR20100014090A (en)
CN (1) CN102149381A (en)
CA (1) CA2732864A1 (en)
WO (1) WO2010013975A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9187485B2 (en) 2007-02-02 2015-11-17 Baylor College Of Medicine Methods and compositions for the treatment of cancer and related hyperproliferative disorders
JP2011529875A (en) * 2008-08-01 2011-12-15 ドン ファ ファーマシューティカル カンパニー リミテッド Pharmaceutical composition for preventing or treating osteoporosis comprising a benzamidine derivative or a salt thereof and alendronic acid or a salt thereof
CN107074839A (en) * 2013-08-29 2017-08-18 贝勒医学院 Composition and method for treating the metabolism illness related to body weight
US20170301910A1 (en) 2014-09-29 2017-10-19 A123 Systems Llc Pre-lithiated silicon anodes with pvdf binder
EP3846793B1 (en) 2018-09-07 2024-01-24 PIC Therapeutics, Inc. Eif4e inhibitors and uses thereof
US11753403B2 (en) 2020-03-03 2023-09-12 PIC Therapeutics, Inc. EIF4E inhibitors and uses thereof
JP2024532276A (en) 2021-08-25 2024-09-05 ピク セラピューティクス， インコーポレイテッド eIF4E inhibitors and uses thereof
CA3229560A1 (en) 2021-08-25 2023-03-02 Christopher L. Vandeusen Eif4e inhibitors and uses thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001001991A1 (en) * 1999-07-01 2001-01-11 Merck & Co., Inc. Pharmaceutical tablets
WO2004056373A1 (en) * 2002-12-20 2004-07-08 F. Hoffmann-La Roche Ag High dose ibandronate formulation
WO2007089101A1 (en) * 2006-01-31 2007-08-09 Dong Wha Pharmaceutical Ind.Co., Ltd. Novel benzamidine derivatives, process for the preparation thereof and pharmaceutical composition comprising the same
WO2009017222A1 (en) * 2007-08-02 2009-02-05 Teijin Pharma Limited Preventive agent or therapeutic agent for disease caused by abnormal bone metabolism

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5451700A (en) * 1991-06-11 1995-09-19 Ciba-Geigy Corporation Amidino compounds, their manufacture and methods of treatment
US6150390A (en) * 1997-02-04 2000-11-21 Dong Wha Pharm. Ind. Co., Ltd. 3-amino-1,2-benzoisoxazole derivatives, process for preparation, and use thereof
US5998390A (en) * 1998-09-28 1999-12-07 The Research Foundation Of State University Of New York Combination of bisphosphonate and tetracycline
KR100317935B1 (en) * 1999-10-20 2001-12-22 유승필 Pharmaceutical compositions and preparations for treatment of metabolic bone disease
KR100454767B1 (en) * 2001-07-19 2004-11-03 동화약품공업주식회사 Use of 4-[(4-thiazolyl)phenoxy]alkoxy-benzamidine derivatives for treatment of osteoporosis
JP2003292453A (en) * 2002-04-02 2003-10-15 Asahi Kasei Corp Pharmaceutical combination for bone disease treatment
US20060173009A1 (en) * 2003-01-07 2006-08-03 Hiroyuki Kanoh Agent inducing increase in bone mass
WO2005039485A2 (en) * 2003-08-13 2005-05-06 Chiron Corporation Gsk-3 inhibitors and uses thereof
US7410977B2 (en) * 2004-04-28 2008-08-12 Merck & Co., Inc. Fluorinated 4-azasteroids as androgen receptor modulators
US7923443B2 (en) * 2004-07-05 2011-04-12 Dong Wha Pharmaceutical Co., Ltd. Pharmaceutical composition for the treatment of bone fracture
JP2009017222A (en) * 2007-07-04 2009-01-22 Panasonic Corp Color adjustment apparatus, color adjustment method, and integrated circuit of color adjustment apparatus
JP2011529875A (en) * 2008-08-01 2011-12-15 ドン ファ ファーマシューティカル カンパニー リミテッド Pharmaceutical composition for preventing or treating osteoporosis comprising a benzamidine derivative or a salt thereof and alendronic acid or a salt thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001001991A1 (en) * 1999-07-01 2001-01-11 Merck & Co., Inc. Pharmaceutical tablets
WO2004056373A1 (en) * 2002-12-20 2004-07-08 F. Hoffmann-La Roche Ag High dose ibandronate formulation
WO2007089101A1 (en) * 2006-01-31 2007-08-09 Dong Wha Pharmaceutical Ind.Co., Ltd. Novel benzamidine derivatives, process for the preparation thereof and pharmaceutical composition comprising the same
WO2009017222A1 (en) * 2007-08-02 2009-02-05 Teijin Pharma Limited Preventive agent or therapeutic agent for disease caused by abnormal bone metabolism

Also Published As

Publication number Publication date
WO2010013975A2 (en) 2010-02-04
WO2010013975A3 (en) 2010-06-03
KR20100014174A (en) 2010-02-10
JP2011529876A (en) 2011-12-15
CA2732864A1 (en) 2010-02-04
EP2307016A2 (en) 2011-04-13
CN102149381A (en) 2011-08-10
KR20100014090A (en) 2010-02-10

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