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EP2366415B1 - Injection device - Google Patents

Injection device Download PDF

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Publication number
EP2366415B1
EP2366415B1 EP11169691A EP11169691A EP2366415B1 EP 2366415 B1 EP2366415 B1 EP 2366415B1 EP 11169691 A EP11169691 A EP 11169691A EP 11169691 A EP11169691 A EP 11169691A EP 2366415 B1 EP2366415 B1 EP 2366415B1
Authority
EP
European Patent Office
Prior art keywords
trigger
locking mechanism
releasable locking
protrusion
injection device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP11169691A
Other languages
German (de)
French (fr)
Other versions
EP2366415A1 (en
Inventor
Rosemary Burnell
Jonathan Hogwood
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cilag GmbH International
Original Assignee
Cilag GmbH International
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cilag GmbH International filed Critical Cilag GmbH International
Priority to PL11169691T priority Critical patent/PL2366415T3/en
Publication of EP2366415A1 publication Critical patent/EP2366415A1/en
Application granted granted Critical
Publication of EP2366415B1 publication Critical patent/EP2366415B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2006—Having specific accessories
    • A61M2005/2013—Having specific accessories triggering of discharging means by contact of injector with patient body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/206—With automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
    • A61M2005/208—Release is possible only when device is pushed against the skin, e.g. using a trigger which is blocked or inactive when the device is not pushed against the skin

Definitions

  • the present invention relates to an injection device of the type that receives a syringe, extends it, discharges its contents and then retracts it automatically.
  • Previously known injection devices are shown in WO 95/35126 and EP-A-0 516 473 and tend to employ a drive spring and a trigger that, when activated, causes the drive spring to act on the syringe when a releasable locking mechanism is also engaged.
  • WO 2005/115510 also discloses an injection device of this kind.
  • the trigger is rotatable about an axis so that when it is depressed at a first end, a second end (which normally engages the drive spring) is also rotated, thereby releasing the drive spring, extending the syringe and discharging its contents.
  • the trigger comprises a protrusion which is engageable with a cut-out on the releasable locking mechanism when the releasable locking mechanism is engaged, thereby allowing the trigger to be activated.
  • the protrusion abuts a portion of the releasable locking mechanism preventing rotation of the trigger and release of the drive spring. This way, accidental activation of the trigger can be prevented.
  • a problem with an injection device of this type is that the protrusion on the trigger flexes when a force is applied to the trigger and the releasable locking mechanism is not engaged.
  • a strong force applied to the trigger can cause enough flex in the protrusion that the end of the protrusion can engage the cut-out on the releasable locking mechanism, thereby allowing the trigger to be activated even when the releasable locking mechanism has not been engaged.
  • US 6575939 B describes an injection device having a locking mechanism which prevents the trigger from being activated until the locking mechanism is moved to an activation position.
  • the trigger comprises a lateral bar which must marry with corresponding apertures in the locking mechanism before it can be activated.
  • WO 03/047663 A2 discloses an automatic injector comprising a needle which is automatically injected into the injection site upon activation of the injector.
  • the device may comprise a needle-locking device including a clip which insures that the needle assembly is in a locked position before and after use.
  • US4194505 discloses a hypodermic module having a trigger comprising a trigger element which prevents the release of a plunger until the trigger is pressed.
  • the trigger further comprises a pin, which must marry with an opening before it can be pressed.
  • the injection device of the present invention is designed to deal with this and other problems.
  • an injection device comprising:
  • the first port ion of the trigger and the protrusion both flex in such a way that the protrusion is forced away from the cut-out, thereby decreasing the risk of accidental activation of the trigger.
  • the trigger may further include a second portion which extends into the cut-out from the first portion of the trigger and which is arranged to communicate with the ridge when the releasable locking mechanism is in its second position and the trigger is in its active position.
  • the trigger can be maintained in a rotated position following activation, thereby serving to indicate that the injection device has been used.
  • the releasable locking mechanism comprises biasing means arranged to bias the protrusion against the second portion.
  • the first portion of the trigger comprises a second ridge positioned on the first portion such that the protrusion is located between the cut-out and the second ridge when the trigger is in its rest position such that the second ridge communicates with the protrusion if an attempt is made to move the trigger from its rest position.
  • the second ridge prevents the first portion of the trigger and the protrusion flexing in such a way that the end of the protrusion extends beyond the end of the first portion which would result in the trigger being able to rotate.
  • the protrusion may comprise a sloped surface which is angled with respect to the second axis, thereby ensuring that the protrusion enters the cut-out smoothly when the locking mechanism is disengaged.
  • the first axis and second axis are perpendicular to each other which ensures that the protrusion and first portion are optimally arranged to ensure that the protrusion enters the cut-out when the locking mechanism is disengaged, but also means that the protrusion and first portion will flex in such a way to avoid accidental activation of the trigger when the release mechanism is engaged.
  • Figures 1 to 4 show an injection device 110 according to a first embodiment of the present invention.
  • the injection device 110 has an injection device housing 112 and a longitudinal axis 101.
  • a syringe 122 is contained in the housing 112.
  • the injection device 110 comprises trigger 114 and a releasable locking mechanism 116.
  • the trigger 114 has a first end 114a and a second end 114b.
  • the trigger 114 is rotatable about a pivot 115 from a rest position (as shown in Figure 2 ) to an active position.
  • the second end 114b of the trigger 114 connects with a drive coupling 121 which is acted upon by a drive spring 120.
  • the drive coupling 121 is in communication with the syringe 122.
  • Rotation of the trigger 114 about the pivot 115 in a direction R causes the second end 114b of the trigger 114 to disengage from the drive coupling 121, thereby letting the drive spring 120 drive the syringe 122 (via the drive coupling 121) along the longitudinal axis 101 and out of an aperture 118 in the housing 112.
  • the releasable locking mechanism 116 is in communication with sliding sleeve 126 which protrudes, when in a first position, from the aperture 118 in the housing 112.
  • the locking mechanism 116 is deactivated by movement of the sliding sleeve 126 along the longitudinal axis 101 into the housing 112 into a second position.
  • a first end 126a of the sliding sleeve 126 can be placed against a body into which drug is being delivered, thereby deactivating the releasable locking mechanism 116 and allowing the trigger 114 to rotate in direction R from its rest position to its active position.
  • the trigger 114 is provided at its first end 114a with a first portion 150 having a cut-out 152.
  • the first portion 150 extends from the first end 114a of the trigger 114a in a direction substantially parallel to the longitudinal axis 101.
  • the releasable locking mechanism 116 includes a protrusion 154 which projects in a direction along a perpendicular axis 181 which is perpendicular to the longitudinal axis 101.
  • the cut-out 152 is dimensioned to receive the protrusion 154.
  • the cut-out 152 is positioned above the end of the protrusion 154 allowing it to pass over the protrusion 154 when a downwards force is applied the trigger 112. Hence, the trigger 112 is no longer prevented from rotating and disengages itself from the drive coupling 121, thereby extending the syringe 122.
  • the protrusion 154 comprises a first ridge 160.
  • the trigger 114 includes a second portion 162 which extends into the cut-out 152 from the first portion 150 of the trigger 114 and which is arranged to communicate with the second portion 162 following rotation of the trigger 114 so that the first ridge 160 is locked over the second portion 162, thereby preventing movement of the trigger 114 from its active position back to its rest position.
  • the locking mechanism 116 includes biasing means, in the form of resilient arms 171, which act against the internal surface of the housing 112 to bias the locking mechanism 116 and sliding sleeve 126 in a direction out of aperture 118. This way, following activation of the trigger 112, the first ridge 160 is locked over the second portion 162 of the trigger 112, thereby holding the trigger 112 in its active position.
  • the first portion 150 of the trigger comprises a second ridge 164 on the under-surface 156 of the first portion 150 which is positioned between the cut-out 152 and the end of the first portion 150.
  • the second ridge 164 abuts the protrusion 154 when force is applied to the trigger 114 in a direction R and the release mechanism is in its first (i.e. engaged) position. This prevents the protrusion 154 from moving into a position in which its end 154a moves over the end of the first portion 150 which would allow the trigger 114 to rotate whilst the releasable locking mechanism 116 was still engaged, thereby accidentally "firing" the injection device 110.
  • the protrusion 154 has a sloped surface 166 which is angled with respect to the second axis 181 which allows the second portion 162 of the trigger 114 to pass over the protrusion 154 more effectively when the trigger 114 is rotated and the releasable locking mechanism 116 is disengaged.

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Vascular Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Catching Or Destruction (AREA)
  • Injection Moulding Of Plastics Or The Like (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Polarising Elements (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Eye Examination Apparatus (AREA)
  • Noodles (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

An injection device is provided which includes a syringe having a discharge nozzle. The syringe is movable between a retracted position in which the discharge nozzle is contained within the housing and an extended position in which the discharge nozzle extends from the housing. A trigger is activatable to allow the contents of the syringe to be discharged through the discharge nozzle. There is also a releasable locking mechanism which, when engaged, prevents the trigger from moving into an active position. The trigger includes a first portion having a cut-out which extends from a first end of the trigger in a direction substantially parallel to the first axis. The releasable locking mechanism includes a protrusion along a second axis for communicating with the first portion of the trigger when the releasable locking mechanism is engaged and for communicating with the cut-out when the releasable locking mechanism is disengaged. Such an injection device provides improved protection against accidental activation of the trigger.

Description

    FIELD OF THE INVENTION
  • The present invention relates to an injection device of the type that receives a syringe, extends it, discharges its contents and then retracts it automatically.
    • BACKGROUND OF THE INVENTION
  • Previously known injection devices are shown in WO 95/35126 and EP-A-0 516 473 and tend to employ a drive spring and a trigger that, when activated, causes the drive spring to act on the syringe when a releasable locking mechanism is also engaged. WO 2005/115510 also discloses an injection device of this kind.
  • Generally, the trigger is rotatable about an axis so that when it is depressed at a first end, a second end (which normally engages the drive spring) is also rotated, thereby releasing the drive spring, extending the syringe and discharging its contents. The trigger comprises a protrusion which is engageable with a cut-out on the releasable locking mechanism when the releasable locking mechanism is engaged, thereby allowing the trigger to be activated. When the releasable locking mechanism is not engaged, the protrusion abuts a portion of the releasable locking mechanism preventing rotation of the trigger and release of the drive spring. This way, accidental activation of the trigger can be prevented.
  • A problem with an injection device of this type is that the protrusion on the trigger flexes when a force is applied to the trigger and the releasable locking mechanism is not engaged. A strong force applied to the trigger can cause enough flex in the protrusion that the end of the protrusion can engage the cut-out on the releasable locking mechanism, thereby allowing the trigger to be activated even when the releasable locking mechanism has not been engaged.
  • US 6575939 B describes an injection device having a locking mechanism which prevents the trigger from being activated until the locking mechanism is moved to an activation position. The trigger comprises a lateral bar which must marry with corresponding apertures in the locking mechanism before it can be activated.
  • WO 03/047663 A2 discloses an automatic injector comprising a needle which is automatically injected into the injection site upon activation of the injector. The device may comprise a needle-locking device including a clip which insures that the needle assembly is in a locked position before and after use.
  • US4194505 discloses a hypodermic module having a trigger comprising a trigger element which prevents the release of a plunger until the trigger is pressed. The trigger further comprises a pin, which must marry with an opening before it can be pressed.
    • SUMMARY OF THE INVENTION
  • The injection device of the present invention is designed to deal with this and other problems.
  • In view of the foregoing and in accordance with a first aspect of the invention, there is provided an injection device comprising:
    • a housing defining a first axis and adapted to receive a syringe having a discharge nozzle so that the syringe is movable between a retracted position in which the discharge nozzle is contained within the housing and an extended position in which the discharge nozzle extends from the housing through an exit aperture;
    • a drive that is acted upon and in turn acts upon the syringe;
    • a trigger movable from a rest position, in which it causes the drive to be retained, to an active position, in which it no longer causes the drive to be so retained, thus allowing the contents of the syringe to be discharged through the discharge nozzle; and
    • a releasable locking mechanism movable from a first position in which the trigger is prevented from moving into its active position to a second position in which the trigger can be moved into its active position,
    • characterised in that the trigger includes a first portion having a cut-out therein, the first portion extending from a first end of the trigger in a direction substantially parallel to the first axis; and the releasable locking mechanism includes a protrusion along a second axis for communicating with the first portion of the trigger when the releasable locking mechanism is in its first position and for communicating with the cut-out when the releasable locking mechanism is in its second position; and
    • the protrusion comprises a first ridge adapted to communicate with an edge of the cut-out when the releasable locking mechanism is in its second position and the trigger is in its active position, thereby preventing movement of the trigger from its active position to its rest position.
  • Thus, when a force is applied to the trigger when the locking mechanism is in its first position (i.e. engaged), the first port ion of the trigger and the protrusion both flex in such a way that the protrusion is forced away from the cut-out, thereby decreasing the risk of accidental activation of the trigger.
  • In addition, the trigger may further include a second portion which extends into the cut-out from the first portion of the trigger and which is arranged to communicate with the ridge when the releasable locking mechanism is in its second position and the trigger is in its active position.
  • Accordingly, the trigger can be maintained in a rotated position following activation, thereby serving to indicate that the injection device has been used.
  • Preferably, the releasable locking mechanism comprises biasing means arranged to bias the protrusion against the second portion.
  • Advantageously, the first portion of the trigger comprises a second ridge positioned on the first portion such that the protrusion is located between the cut-out and the second ridge when the trigger is in its rest position such that the second ridge communicates with the protrusion if an attempt is made to move the trigger from its rest position.
  • The second ridge prevents the first portion of the trigger and the protrusion flexing in such a way that the end of the protrusion extends beyond the end of the first portion which would result in the trigger being able to rotate.
  • The protrusion may comprise a sloped surface which is angled with respect to the second axis, thereby ensuring that the protrusion enters the cut-out smoothly when the locking mechanism is disengaged.
  • Preferably, the first axis and second axis are perpendicular to each other which ensures that the protrusion and first portion are optimally arranged to ensure that the protrusion enters the cut-out when the locking mechanism is disengaged, but also means that the protrusion and first portion will flex in such a way to avoid accidental activation of the trigger when the release mechanism is engaged.
    • BRIEF DESCRIPTION OF THE DRAWINGS
  • The invention will now be described by way of example with reference to the accompanying drawings, in which:
    • Figure 1 shows a perspective view of an injection device according to the present invention;
    • Figure 2 shows a side view of the injection device of figure 1 with an upper section of its housing not shown;
    • Figure 3 shows a side view of the injection device of figure 2 with further components not shown;
    • Figure 4 shows a top plan view of the injection device of figure 2;
    • Figure 5 shows a perspective view of a trigger and releasable locking mechanism according to an embodiment of the present invention; and
    • Figure 6 shows an alternative perspective view of the trigger and releasable locking mechanism of Figure 5.
    DETAILED DESCRIPTION OF THE DRAWINGS
  • Figures 1 to 4 show an injection device 110 according to a first embodiment of the present invention. The injection device 110 has an injection device housing 112 and a longitudinal axis 101.
  • A syringe 122 is contained in the housing 112. The injection device 110 comprises trigger 114 and a releasable locking mechanism 116. The trigger 114 has a first end 114a and a second end 114b. The trigger 114 is rotatable about a pivot 115 from a rest position (as shown in Figure 2) to an active position. The second end 114b of the trigger 114 connects with a drive coupling 121 which is acted upon by a drive spring 120. The drive coupling 121 is in communication with the syringe 122.
  • Rotation of the trigger 114 about the pivot 115 in a direction R (i.e. downwards into the housing 112 at its first end 114a) causes the second end 114b of the trigger 114 to disengage from the drive coupling 121, thereby letting the drive spring 120 drive the syringe 122 (via the drive coupling 121) along the longitudinal axis 101 and out of an aperture 118 in the housing 112.
  • The releasable locking mechanism 116 is in communication with sliding sleeve 126 which protrudes, when in a first position, from the aperture 118 in the housing 112. The locking mechanism 116 is deactivated by movement of the sliding sleeve 126 along the longitudinal axis 101 into the housing 112 into a second position.
  • A first end 126a of the sliding sleeve 126 can be placed against a body into which drug is being delivered, thereby deactivating the releasable locking mechanism 116 and allowing the trigger 114 to rotate in direction R from its rest position to its active position.
  • As can be seen from Figures 5 and 6, the trigger 114 is provided at its first end 114a with a first portion 150 having a cut-out 152. The first portion 150 extends from the first end 114a of the trigger 114a in a direction substantially parallel to the longitudinal axis 101.
  • The releasable locking mechanism 116 includes a protrusion 154 which projects in a direction along a perpendicular axis 181 which is perpendicular to the longitudinal axis 101. The cut-out 152 is dimensioned to receive the protrusion 154.
  • When the releasable locking mechanism 116 is in its first position, an end 154a of the protrusion 154 abuts an under-surface 156 of the first portion 150, thereby preventing rotation of the trigger 114.
  • When the releasable locking mechanism 116 is in its second position (not shown) following movement of the sliding sleeve 126 into the housing 112, the cut-out 152 is positioned above the end of the protrusion 154 allowing it to pass over the protrusion 154 when a downwards force is applied the trigger 112. Hence, the trigger 112 is no longer prevented from rotating and disengages itself from the drive coupling 121, thereby extending the syringe 122.
  • The protrusion 154 comprises a first ridge 160. The trigger 114 includes a second portion 162 which extends into the cut-out 152 from the first portion 150 of the trigger 114 and which is arranged to communicate with the second portion 162 following rotation of the trigger 114 so that the first ridge 160 is locked over the second portion 162, thereby preventing movement of the trigger 114 from its active position back to its rest position.
  • The locking mechanism 116 includes biasing means, in the form of resilient arms 171, which act against the internal surface of the housing 112 to bias the locking mechanism 116 and sliding sleeve 126 in a direction out of aperture 118. This way, following activation of the trigger 112, the first ridge 160 is locked over the second portion 162 of the trigger 112, thereby holding the trigger 112 in its active position.
  • The first portion 150 of the trigger comprises a second ridge 164 on the under-surface 156 of the first portion 150 which is positioned between the cut-out 152 and the end of the first portion 150. The second ridge 164 abuts the protrusion 154 when force is applied to the trigger 114 in a direction R and the release mechanism is in its first (i.e. engaged) position. This prevents the protrusion 154 from moving into a position in which its end 154a moves over the end of the first portion 150 which would allow the trigger 114 to rotate whilst the releasable locking mechanism 116 was still engaged, thereby accidentally "firing" the injection device 110.
  • The protrusion 154 has a sloped surface 166 which is angled with respect to the second axis 181 which allows the second portion 162 of the trigger 114 to pass over the protrusion 154 more effectively when the trigger 114 is rotated and the releasable locking mechanism 116 is disengaged.
  • It will of course be understood that the present invention has been described above purely by way of example and modifications of detail can be made within the scope of the invention.

Claims (6)

  1. An injection device (110) comprising:
    a housing defining a first axis (101) and adapted to receive a syringe (122) having a discharge nozzle so that the syringe (122) is movable between a retracted position in which the discharge nozzle is contained within the housing (112) and an extended position in which the discharge nozzle extends from the housing (112) through an exit aperture;
    a drive that is acted upon and in turn acts upon the syringe (122);
    a trigger (114) movable from a rest position, in which it causes the drive to be retained, to an active position, in which it no longer causes the drive to be so retained, thus allowing the contents of the syringe (122) to be discharged through the discharge nozzle; and
    a releasable locking mechanism (116) movable from a first position in which the trigger (114) is prevented from moving into its active position to a second position in which the trigger (114) can be moved into its active position, characterised in that:
    the trigger (114) includes a first portion (150) having a cut-out (152) therein, the first portion (150) extending from a first end of the trigger (114) in a direction substantially parallel to the first axis (101); and the releasable locking mechanism (116) includes a protrusion (154) along a second axis (181) for communicating with the first portion (150) of the trigger (114) when the releasable locking mechanism (116) is in its first position and for communicating with the cut-out (152) when the releasable locking mechanism (116) is in its second position; and
    the protrusion (154) comprises a ridge adapted to communicate with an edge of the cut-out (152) when the releasable locking mechanism (116) is in its second position and the trigger (114) is in its active position, thereby preventing movement of the trigger (114) from its active position to its rest position.
  2. The injection device of claim 1 wherein the trigger (114) further includes a second portion (162) which extends into the cut-out (152) from the first portion of the trigger (114) and which is arranged to communicate with the ridge when the releasable locking mechanism (116) is in its second position and the trigger (114) is in its active position.
  3. The injection device (110) of claim 2, wherein the releasable locking mechanism (116) comprises biasing means arranged to bias the protrusion (154) against the second portion (162).
  4. The injection device (110) of any one of the preceding claims wherein the first portion (150) of the trigger (114) comprises a ridge positioned on the first portion (150) such that the protrusion (154) is located between the cut-out and the ridge when the trigger (114) is in its rest position such that the ridge communicates with the protrusion (154) if an attempt is made to move the trigger (114) from its rest position.
  5. The injection device (110) of any one of the preceding claims, wherein the protrusion (154) comprises a sloped surface which is angled with respect to the second axis (181).
  6. The injection device (110) of any one of the preceding claims, wherein the first axis (101) and second axis (181) are perpendicular to each other.
EP11169691A 2005-04-06 2006-03-21 Injection device Active EP2366415B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL11169691T PL2366415T3 (en) 2005-04-06 2006-03-21 Injection device

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0507009A GB2424835B (en) 2005-04-06 2005-04-06 Injection device (modified trigger)
EP06710133A EP1888146B1 (en) 2005-04-06 2006-03-21 Injection device (modified trigger)

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
EP06710133.7 Division 2006-03-21

Publications (2)

Publication Number Publication Date
EP2366415A1 EP2366415A1 (en) 2011-09-21
EP2366415B1 true EP2366415B1 (en) 2012-12-26

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
EP11169691A Active EP2366415B1 (en) 2005-04-06 2006-03-21 Injection device
EP06710133A Active EP1888146B1 (en) 2005-04-06 2006-03-21 Injection device (modified trigger)

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP06710133A Active EP1888146B1 (en) 2005-04-06 2006-03-21 Injection device (modified trigger)

Country Status (22)

Country Link
US (1) US8317751B2 (en)
EP (2) EP2366415B1 (en)
JP (1) JP4987852B2 (en)
KR (1) KR101308384B1 (en)
CN (1) CN101287511B (en)
AT (1) ATE512683T1 (en)
AU (1) AU2006231102B2 (en)
BR (1) BRPI0608663B8 (en)
CA (1) CA2603664C (en)
DK (2) DK2366415T3 (en)
EA (1) EA012075B1 (en)
ES (2) ES2365862T3 (en)
GB (1) GB2424835B (en)
IL (1) IL186370A (en)
MX (1) MX2007012268A (en)
NO (2) NO339250B1 (en)
NZ (1) NZ562164A (en)
PL (2) PL2366415T3 (en)
PT (2) PT2366415E (en)
UA (1) UA96127C2 (en)
WO (1) WO2006106293A1 (en)
ZA (1) ZA200709509B (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2414401B (en) 2004-05-28 2009-06-17 Cilag Ag Int Injection device
GB2414775B (en) 2004-05-28 2008-05-21 Cilag Ag Int Releasable coupling and injection device
GB2414399B (en) 2004-05-28 2008-12-31 Cilag Ag Int Injection device
GB2414409B (en) 2004-05-28 2009-11-18 Cilag Ag Int Injection device
GB2414402B (en) 2004-05-28 2009-04-22 Cilag Ag Int Injection device
GB2414406B (en) 2004-05-28 2009-03-18 Cilag Ag Int Injection device
GB2414400B (en) 2004-05-28 2009-01-14 Cilag Ag Int Injection device
GB2414403B (en) 2004-05-28 2009-01-07 Cilag Ag Int Injection device
GB2424836B (en) 2005-04-06 2010-09-22 Cilag Ag Int Injection device (bayonet cap removal)
GB2427826B (en) 2005-04-06 2010-08-25 Cilag Ag Int Injection device comprising a locking mechanism associated with integrally formed biasing means
GB2425062B (en) 2005-04-06 2010-07-21 Cilag Ag Int Injection device
GB2424838B (en) 2005-04-06 2011-02-23 Cilag Ag Int Injection device (adaptable drive)
GB2424835B (en) 2005-04-06 2010-06-09 Cilag Ag Int Injection device (modified trigger)
ES2340936T3 (en) 2005-08-30 2010-06-11 Cilag Gmbh International NEEDLE ASSEMBLY FOR A PRE-LOADED SYRINGE SYSTEM.
US20110098656A1 (en) 2005-09-27 2011-04-28 Burnell Rosie L Auto-injection device with needle protecting cap having outer and inner sleeves
GB2438591B (en) † 2006-06-01 2011-07-13 Cilag Gmbh Int Injection device
GB2438590B (en) 2006-06-01 2011-02-09 Cilag Gmbh Int Injection device
GB2438593B (en) 2006-06-01 2011-03-30 Cilag Gmbh Int Injection device (cap removal feature)
GB2443606B (en) * 2006-11-13 2011-07-20 Cilag Gmbh Int Injection device
GB2461086B (en) 2008-06-19 2012-12-05 Cilag Gmbh Int Injection device
GB2461087B (en) 2008-06-19 2012-09-26 Cilag Gmbh Int Injection device
GB2461089B (en) 2008-06-19 2012-09-19 Cilag Gmbh Int Injection device
GB2461085B (en) 2008-06-19 2012-08-29 Cilag Gmbh Int Injection device
GB2461084B (en) 2008-06-19 2012-09-26 Cilag Gmbh Int Fluid transfer assembly
CN102753233B (en) * 2009-12-16 2015-04-01 贝克顿·迪金森公司 Self-injection device
DK2986333T3 (en) * 2013-04-19 2020-09-07 Zurex Pharma Inc MEDICAL SKIN APPLICATOR APPLIANCE
GB2515032A (en) 2013-06-11 2014-12-17 Cilag Gmbh Int Guide for an injection device
GB2515039B (en) * 2013-06-11 2015-05-27 Cilag Gmbh Int Injection Device
GB2517896B (en) 2013-06-11 2015-07-08 Cilag Gmbh Int Injection device
GB2515038A (en) 2013-06-11 2014-12-17 Cilag Gmbh Int Injection device
GB2516784B (en) * 2013-06-11 2015-10-21 Cilag Gmbh Int Injection device
TWI577410B (en) * 2013-10-25 2017-04-11 卡貝歐洲有限公司 Trigger mechanism of auto injector
AU2020228948B2 (en) 2019-02-26 2022-09-08 Becton Dickinson France Auto-injector with audio indicator

Family Cites Families (387)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE356704C (en) 1918-03-15 1922-07-27 Edmondo Luswergh Dr syringe
US1845036A (en) * 1930-03-12 1932-02-16 Herbert H Busher Hypodermic syringe
US2019382A (en) 1935-02-19 1935-10-29 Art Metal Works Inc Torch
US2531267A (en) 1947-10-16 1950-11-21 Harnisch Fritz Hypodermic syringe operating device
FR1078911A (en) 1949-08-17 1954-11-24 Automatic hypodermic syringe and its ampoule
FR1014881A (en) 1950-03-21 1952-08-25 Automatic device for parenteral injections
US2764977A (en) 1951-05-24 1956-10-02 Becton Dickinson Co Hypodermic injection mechanism
FR1169935A (en) 1957-03-22 1959-01-07 S E D A T Soc D Etudes Et D Ap Improvements to auto-injectable ampoules
US2828742A (en) * 1957-05-02 1958-04-01 American Home Prod Cartridge-needle unit
GB909898A (en) 1958-04-17 1962-11-07 Donald Travers Lewis Improvements in or relating to a device for automatically effecting injections with a hypodermic syringe
US3329146A (en) 1963-10-02 1967-07-04 Baxter Laboratories Inc Needle container
FR1538565A (en) 1967-07-26 1968-09-06 Automatic hypodermic syringe
US3543603A (en) 1968-01-10 1970-12-01 Rex Chainbelt Inc Automatic quick release mechanism
NO124977B (en) 1968-08-09 1972-07-03 Philips Nv
FR2040830A5 (en) 1969-04-15 1971-01-22 Ben Moura Pierre
BE755224A (en) 1969-08-25 1971-02-24 Philips Nv INJECTION SYRINGE
DE6944378U (en) 1969-11-14 1970-04-16 Georg A Henke Gmbh Fa SELF-INJECTING DEVICE
US3702608A (en) 1970-12-15 1972-11-14 Robert C Tibbs Painless injection device with powered plunger
BE795162A (en) * 1972-02-10 1973-08-08 Philips Nv INJEKTIE-INRICHTING
US3797488A (en) * 1972-07-10 1974-03-19 Ampoules Inc Ampoule applicator with one-way clutch
US3880163A (en) * 1973-10-26 1975-04-29 Jack H Ritterskamp Medicinal syringe actuating device
GB1514725A (en) 1975-05-23 1978-06-21 Everett Med Prod Ltd Hyperdermic needle assembly
US4165739A (en) 1976-09-02 1979-08-28 Doherty Norman R Inoculator
US4180070A (en) 1977-08-29 1979-12-25 Abbott Laboratories Disposable double vial syringe
DE2812729A1 (en) 1978-03-23 1979-09-27 Michael Becker INJECTION DEVICE FOR INTRAMUSCULAR INJECTION, PRESENTLY OF INSULIN
US4185628A (en) * 1978-05-31 1980-01-29 Kopfer Rudolph J Compartmental syringe
US4194505A (en) * 1978-09-15 1980-03-25 Vac-O-Cast, Inc. Containerized hypodermic module
US4299238A (en) 1980-06-24 1981-11-10 Baidwan Balinderjeet S Vented piston and push-rod subassembly for use in a syringe barrel
FR2506161A1 (en) 1981-05-20 1982-11-26 Alsetex Armement Self:injection syringe with compartments for specific liquids - is spring:loaded first to penetrate patient then inject liq.(s), is automatic
US4407283A (en) 1981-10-19 1983-10-04 Dale C. Grier Self-injecting syringe
US4394863A (en) 1981-10-23 1983-07-26 Survival Technology, Inc. Automatic injector with cartridge having separate sequentially injectable medicaments
US4378015A (en) * 1981-12-21 1983-03-29 Wardlaw Stephen C Automatic injecting syringe
US4425120A (en) * 1982-04-15 1984-01-10 Sampson Norma A Shielded hypodermic syringe
US4430080A (en) 1982-06-09 1984-02-07 Becton, Dickinson And Company Syringe assembly with snap-fit components
US4430082A (en) * 1982-06-25 1984-02-07 Hoffmann-La Roche Inc. Hypodermic syringe assembly
US4500310A (en) 1982-12-20 1985-02-19 Becton, Dickinson And Company Variable sealing pressure plunger rod assembly
US4521237A (en) 1983-05-23 1985-06-04 Kahle Engineering Co. Glass dose syringe
US4561856A (en) 1983-08-18 1985-12-31 Cochran Ulrich D Infusion pump
DE3342407A1 (en) 1983-11-24 1985-06-05 Erwin 6950 Mosbach Maurer INJECTION DEVICE
DD229932A1 (en) 1984-12-03 1985-11-20 Nordhausen Veb Fernmeldewerk INJECTION PISTOL, ESPECIALLY FOR METAL-GLASS SPRAYING
DD234613A1 (en) 1985-02-14 1986-04-09 Karl Marx Stadt Tech Hochschul DEVICE WITH DAY MEDICATION DEPOT FOR PAIN-RELIEF INJECTION
US4636201A (en) * 1985-11-01 1987-01-13 American Hospital Supply Corporation Hypodermic syringe having a protective sheath cover
US4636198A (en) 1985-11-18 1987-01-13 Mallinckrodt, Inc. Power syringe with volume reducing adapter
US4735311A (en) 1986-04-09 1988-04-05 The West Company Needle shield assembly
US4744786A (en) * 1986-06-17 1988-05-17 Cordis Corporation Infusion pump
DE3638984C3 (en) * 1986-11-14 1993-11-18 Haselmeier Wilhelm Fa Injection device
CA1285441C (en) 1987-03-17 1991-07-02 Roy D. Mcnaughton Mcnaughton syringe shield type b
DE3715258C2 (en) * 1987-05-08 1996-10-31 Haselmeier Wilhelm Fa Injection device
WO1988010129A1 (en) 1987-06-25 1988-12-29 Nova Medical Pty. Limited Slow delivery injection device
US4787891A (en) 1987-07-13 1988-11-29 Paul Levin Syringe holder and applicator
AU3071689A (en) 1988-03-01 1989-09-07 Ryan Medical, Inc. Safety needled medical devices capable of one-handed manipulation
JPH0534669Y2 (en) * 1988-03-16 1993-09-02
US5156599A (en) 1988-06-28 1992-10-20 Sherwood Medical Company Syringe and sliding locking needle shield
US5026349A (en) 1988-10-05 1991-06-25 Autoject Systems Inc. Liquid medicament injector system
FR2638359A1 (en) 1988-11-03 1990-05-04 Tino Dalto SYRINGE GUIDE WITH ADJUSTMENT OF DEPTH DEPTH OF NEEDLE IN SKIN
US5263933A (en) 1988-12-14 1993-11-23 Patco Ventures Ltd. Safety syringe needle device with interchangeable and retractable needle platform
US4988339A (en) * 1988-12-30 1991-01-29 Vadher Dinesh L Retractable needle/syringe devices for blood collection, catheterization, and medicinal injection procedures
US4929232A (en) 1989-03-30 1990-05-29 Becton, Dickinson And Company Syringe having tamper evidence features
US6096005A (en) * 1989-07-11 2000-08-01 Mdc Investment Holdings, Inc. Retractable needle medical devices
DE3929777A1 (en) 1989-09-07 1991-03-14 Dieter Dr Lucas INJECTION SYRINGE
GB8926825D0 (en) 1989-11-28 1990-01-17 Glaxo Group Ltd Device
CN2059579U (en) 1989-12-22 1990-07-25 国营建安机械厂 Device for inserting needle into vein for beast
US5057079A (en) 1990-04-03 1991-10-15 Roland Tiemann Sheathing device for after use protection from a syringe needle
WO1992000701A1 (en) 1990-07-04 1992-01-23 Maxwell Edmund Whisson Improved parenteral device
FR2665079A1 (en) 1990-07-27 1992-01-31 Conception Fabr Innovations Me Syringe with disposable needle
GB9100819D0 (en) * 1991-01-15 1991-02-27 Medimech Int Ltd Subcutaneous injector
US5098400A (en) * 1991-02-14 1992-03-24 Sherwood Medical Company Needle shield
US5271744A (en) 1991-04-29 1993-12-21 George C. Kramer System and method for rapid vascular drug delivery
US5868711A (en) * 1991-04-29 1999-02-09 Board Of Regents, The University Of Texas System Implantable intraosseous device for rapid vascular access
US5405362A (en) * 1991-04-29 1995-04-11 The Board Of Regents For The University Of Texas System Interactive external defibrillation and drug injection system
US5176643A (en) * 1991-04-29 1993-01-05 George C. Kramer System and method for rapid vascular drug delivery
US5451210A (en) 1991-04-29 1995-09-19 Lifequest Medical, Inc. System and method for rapid vascular drug delivery
GB9111600D0 (en) * 1991-05-30 1991-07-24 Owen Mumford Ltd Improvements relating to injection devices
GB9115765D0 (en) 1991-07-22 1991-09-04 Britt Adrian J Bacterial enzyme for cocaine detection
DE59202070D1 (en) * 1991-07-24 1995-06-08 Medico Dev Investment Co Injector.
WO1993009723A1 (en) 1991-11-12 1993-05-27 Ramel Urs A Lancet device
GB9200219D0 (en) * 1992-01-07 1992-02-26 Medimech Int Ltd Automatic injectors
EP0562671B1 (en) 1992-03-27 1996-05-29 Duphar International Research B.V Automatic injector
ZA932947B (en) 1992-04-28 1993-10-27 Schering Plough Healthcare Applicator for semisolid medications
IL105706A (en) 1992-05-15 1996-10-16 Safe T Ltd Hollow needle applicator
US5250026A (en) 1992-05-27 1993-10-05 Destron/Idi, Inc. Adjustable precision transponder injector
US5267962A (en) 1992-06-10 1993-12-07 Jenson Robert W Disposable hypodermic syringe with needle safe feature
US5406153A (en) * 1992-06-19 1995-04-11 Iowa State University Research Foundation, Inc. Magnetostrictive vibration generation system
EP0585626A1 (en) 1992-08-14 1994-03-09 Hoechst Aktiengesellschaft Laminated mineral fibre mat
WO1994004207A1 (en) 1992-08-17 1994-03-03 Allard Edward F Method and apparatus for a retracting needle
US5267963A (en) 1992-08-21 1993-12-07 Nicholas Bachynsky Medication injection device
CA2143639C (en) * 1992-09-01 2004-07-20 Edwin L. Adair Sterilizable endoscope with separable disposable tube assembly
US5190526A (en) * 1992-09-18 1993-03-02 Murray Kenneth W Hypodermic safety syringe with retracting needle system
US5569189A (en) * 1992-09-28 1996-10-29 Equidyne Systems, Inc. hypodermic jet injector
AU5293393A (en) * 1992-09-28 1994-04-26 Equidyne Systems, Incorporated Hypodermic jet injector
DE69319753T2 (en) 1992-11-19 1999-04-15 Tebro S.A., Luxembourg AUTOMATIC INJECTION DEVICE FOR PRE-FILLED SYRINGES
IT1256577B (en) 1992-12-11 1995-12-11 Ermanno Greco DEVICE PREPARED FOR THE AUTOMATIC ADMINISTRATION OF A DRUG VIA INTRADERMIC.
US5250037A (en) 1992-12-18 1993-10-05 Becton, Dickinson And Company Syringe having needle isolation features
EP0693946B1 (en) * 1993-03-24 2001-05-16 Owen Mumford Limited Improvements relating to injection devices
US5540666A (en) 1993-03-31 1996-07-30 Immuno Aktiengesellschaft Cannula shield and injection syringe system
WO1995031235A1 (en) 1994-05-16 1995-11-23 Washington Biotech Corporation Modular automatic or manual emergency medicine injection system
US5358489A (en) 1993-05-27 1994-10-25 Washington Biotech Corporation Reloadable automatic or manual emergency injection system
US5540664A (en) 1993-05-27 1996-07-30 Washington Biotech Corporation Reloadable automatic or manual emergency injection system
US5425715A (en) 1993-08-05 1995-06-20 Survival Technology, Inc. Reloadable injector
FR2717086A1 (en) 1994-03-11 1995-09-15 Debiotech Syringe system for mixing two compounds
US5372586A (en) 1993-10-20 1994-12-13 Habley Medical Technology Corp. Telescoping pharmaceutical storage and mixing syringe
CA2135706C (en) 1993-11-15 1999-06-15 Walter E. Cover Retractable-needle cannula insertion set with refinements to better control leakage, retraction speed, and reuse
US5330430A (en) 1993-12-06 1994-07-19 Sullivan Robert J Retractable syringe applicator
FR2715071B1 (en) 1994-01-17 1996-03-01 Aguettant Lab Automatic drug injector.
US5478316A (en) 1994-02-02 1995-12-26 Becton, Dickinson And Company Automatic self-injection device
US5514097A (en) * 1994-02-14 1996-05-07 Genentech, Inc. Self administered injection pen apparatus and method
FR2718357B1 (en) * 1994-04-06 1997-10-03 Defarges Alain Moreau Improvements made to a needleless jet injection device.
GB9408500D0 (en) 1994-04-28 1994-06-22 Pa Consulting Services Improvements in or relating to injection devices
US5411488A (en) * 1994-05-06 1995-05-02 Sterling Winthrop Inc. Pre-filled syringe and pre-filled cartridge having an improved plunger and plunger rod for reducing syringing force
US5609584A (en) * 1994-05-18 1997-03-11 Gettig Technologies, Inc. Adaptor system for use with a syringe
ES2204878T3 (en) 1994-05-30 2004-05-01 B D Medico S.A.R.L. INJECTION DEVICE.
GB9412301D0 (en) 1994-06-17 1994-08-10 Safe T Ltd Hollow-needle drugs etc applicators
DE4428467A1 (en) 1994-08-11 1996-02-15 Dietmar Dr Med Enk Syringe, e.g. for spinal anaesthetics
AUPM922394A0 (en) * 1994-11-03 1994-11-24 Astra Pharmaceuticals Pty Ltd Plastic syringe with overcap
US5637094A (en) 1994-11-04 1997-06-10 Pos-T-Vac, Inc. Multiple dosage syringe
US5599302A (en) * 1995-01-09 1997-02-04 Medi-Ject Corporation Medical injection system and method, gas spring thereof and launching device using gas spring
US5647845A (en) 1995-02-01 1997-07-15 Habley Medical Technology Corporation Generic intravenous infusion system
GB9506087D0 (en) 1995-03-24 1995-05-10 Owen Mumford Ltd Improvements relating to medical injection devices
US5779668A (en) 1995-03-29 1998-07-14 Abbott Laboratories Syringe barrel for lyophilization, reconstitution and administration
FR2733155B1 (en) * 1995-04-18 1997-09-19 Tebro RECHARGEABLE SELF-INJECTOR
FR2736553B1 (en) 1995-07-12 1998-01-09 Soc Et Et D Applic Tech Sedat INJECTION SYRINGE, IN PARTICULAR LIQUID MEDICAL PRODUCTS, WITH MOBILE NEEDLE PROTECTOR
DE29513214U1 (en) 1995-08-21 1997-01-02 Adamaszek, Franz-Heinz, 70193 Stuttgart Dosing and automatic injection system
US5520653A (en) * 1995-09-01 1996-05-28 Medrad, Inc. Syringe adapter for front-loading medical injector
US5674204A (en) 1995-09-19 1997-10-07 Becton Dickinson And Company Medication delivery pen cap actuated dose delivery clutch
FR2739564B3 (en) 1995-10-06 1998-04-10 Calomili Gerard SINGLE USE SAFETY SYRINGE, WITH WHICH THE NEEDLE CANNULA AUTOMATICALLY AND FULLY RETRACTS AFTER FIRST USE
US5807334A (en) 1995-10-20 1998-09-15 Hodosh; Milton Fluid dispensing apparatus
US5567160A (en) 1995-10-26 1996-10-22 Survival Technology, Inc. Autoinjector training device
US5997513A (en) 1995-11-22 1999-12-07 Smith; Jerry A. Syringe cover cooperating with needle cover
FR2741810B1 (en) 1995-11-30 1998-02-20 Soc Et Et D Applic Tech Sedat SYRINGE FOR THE INJECTION OF AN EXTEMPORANEOUS MIXTURE
US5899879A (en) 1995-12-19 1999-05-04 Genesis Medical Technologies, Inc. Spring-actuated needleless injector
US5609577A (en) * 1996-01-29 1997-03-11 Haber; Terry M. Automatically locking hypodermic needle hiding shield for a dose metering syringe
GB9606829D0 (en) 1996-03-30 1996-06-05 Jeffrey Peter Supplying materials etc
IT1284642B1 (en) * 1996-05-02 1998-05-21 Ermanno Greco REFINEMENTS FOR AUTOMATIC SYRINGES FOR INJECTION
GB9612724D0 (en) 1996-06-18 1996-08-21 Owen Mumford Ltd Improvements relating to injection devices
CN1589916A (en) * 1996-07-01 2005-03-09 辉瑞健康公司 Injection device and method for its operation
DE69724784T2 (en) * 1996-07-05 2004-07-15 Novo Nordisk A/S DEVICE FOR AUTOMATICALLY INSERTING A NEEDLE
US5843036A (en) 1996-08-23 1998-12-01 Becton Dickinson And Company Non-dosing cartridge for an injection device
US5709662A (en) * 1996-08-23 1998-01-20 Becton Dickinson France, S.A. Cartridge for an injection device
US5955177A (en) 1996-09-03 1999-09-21 3M Innovative Properties Company Fire barrier mat
WO1998011927A1 (en) 1996-09-20 1998-03-26 Disetronic Licensing Ag Expulsion member for advancing the stopper of a syringe ampoule and a corresponding stopper
US5697908A (en) 1996-09-26 1997-12-16 Becton Dickinson France, S.A. Lockable safety shield for a prefillable syringe
AU7398096A (en) * 1996-10-09 1998-05-05 Equidyne Systems, Incorporated Hypodermic jet injector
US5873861A (en) * 1996-11-12 1999-02-23 Medrad, Inc. Plunger systems
US6090897A (en) 1996-12-09 2000-07-18 Nippon Shokubai Co., Ltd. Curable resin composition and its use
US5817058A (en) 1996-12-23 1998-10-06 Shaw; Thomas J. Retractable catheter introducer structure
US6203530B1 (en) * 1997-01-28 2001-03-20 Pos-T-Vac, Inc. Auto-injection device
BR9700930A (en) 1997-02-07 1998-12-08 Rhone Poulenc Rorer Gmbh Unit for sale intended for parenteral application a device for the execution of parenteral application as well as a refill unit for the above mentioned unit for sale
CN1190599A (en) 1997-02-12 1998-08-19 约尼-鲍伦斯·劳拉有限公司 Complete set of commodity, equipment and spare parts for external use of intestines and stomach
US6454746B1 (en) 1997-06-04 2002-09-24 Eli Lilly And Company Medication delivery apparatus
GB9714948D0 (en) 1997-07-16 1997-09-17 Owen Mumford Ltd Improvements relating to injection devices
US5954738A (en) 1997-07-31 1999-09-21 Bayer Corporation Blood sampling device with lancet damping system
GB9716065D0 (en) * 1997-07-31 1997-10-01 Owen Mumford Ltd Improvements relating to injection devices
US6171276B1 (en) * 1997-08-06 2001-01-09 Pharmacia & Upjohn Ab Automated delivery device and method for its operation
ATE252399T1 (en) 1997-08-21 2003-11-15 Ares Trading Sa INJECTION DEVICE
US6569115B1 (en) 1997-08-28 2003-05-27 Mdc Investment Holdings, Inc. Pre-filled retractable needle injection device
AU9202398A (en) 1997-09-29 1999-04-23 Becton Dickinson & Company Injection device and drug cartridge for preventing cross-use of the device and drug cartridge
US6004296A (en) 1997-09-30 1999-12-21 Becton Dickinson France, S.A. Lockable safety shield assembly for a prefillable syringe
US6090078A (en) 1997-09-30 2000-07-18 Becton, Dickinson And Company Dampening devices and methods for needle retracting safety vascular access devices
IE970782A1 (en) 1997-10-22 1999-05-05 Elan Corp An improved automatic syringe
US6086562A (en) 1997-10-27 2000-07-11 Sarcos, Inc. Disposable automatic injection device
US6045534A (en) * 1997-10-27 2000-04-04 Sarcos, Inc. Disposable fluid injection module
JP2001521793A (en) 1997-10-30 2001-11-13 ラボラトアール アゲータン Medical safety syringe
FR2770404B1 (en) 1997-11-05 2000-01-28 Sedat AUTOMATIC INJECTOR WITH NEEDLE RETRACTION AT THE END OF INJECTION
US6015438A (en) * 1997-11-14 2000-01-18 Retractable Technologies Inc. Full displacement retractable syringe
US5913843A (en) 1997-11-26 1999-06-22 Jentzen; S. William Dampening device for spring movement
CA2575064C (en) 1997-12-31 2010-02-02 Medtronic Minimed, Inc. Insertion device for an insertion set and method of using the same
IT1304761B1 (en) 1998-01-20 2001-03-29 Nardino Righi DISPOSABLE SAFETY SYRINGE.
DE29801168U1 (en) * 1998-01-24 1999-08-12 Medico Dev Investment Co Injection device
FR2774294B1 (en) * 1998-02-04 2000-04-14 Marc Brunel DEVICE FOR AUTOMATICALLY INJECTING A DOSE OF MEDICINAL PRODUCT
GB9803084D0 (en) 1998-02-14 1998-04-08 Owen Mumford Ltd Improvements relating to medical injection devices
GB9808408D0 (en) 1998-04-18 1998-06-17 Owen Mumford Ltd Improvements relating to injection devices
DE19819409A1 (en) 1998-04-30 1999-11-11 Schering Ag Injection device
DE19822031C2 (en) 1998-05-15 2000-03-23 Disetronic Licensing Ag Auto injection device
DE19821933C1 (en) 1998-05-15 1999-11-11 Disetronic Licensing Ag Device for administering an injectable product
FR2778853B1 (en) 1998-05-19 2000-12-22 Sedat INJECTION SYRINGE WITH SPRING LOADED NEEDLE PROTECTOR
GB2338033A (en) 1998-06-02 1999-12-08 Huntleigh Technology Plc Pressure control system
AU5317699A (en) 1998-07-27 2000-02-21 Medi-Ject Corporation Loading mechanism for medical injector assembly
US6358236B1 (en) 1998-08-06 2002-03-19 Baxter International Inc. Device for reconstituting medicaments for injection
US6428528B2 (en) 1998-08-11 2002-08-06 Antares Pharma, Inc. Needle assisted jet injector
GB9817662D0 (en) 1998-08-13 1998-10-07 Crocker Peter J Substance delivery
WO2000013723A2 (en) 1998-09-04 2000-03-16 Owen Mumford Limited Improvements relating to fluid tranfer assemblies
FR2784033B1 (en) 1998-10-01 2000-12-22 Marc Brunel SINGLE USE INJECTION DEVICE FOR PRE-FILLED
US6506177B2 (en) 1998-10-14 2003-01-14 Sergio Landau Needle-less injection system
SE9803662D0 (en) 1998-10-26 1998-10-26 Pharmacia & Upjohn Ab autoinjector
US20020173748A1 (en) 1998-10-29 2002-11-21 Mcconnell Susan Reservoir connector
EP1128858A1 (en) 1998-11-13 2001-09-05 Elan Pharma International Limited Drug delivery systems and methods
US6689093B2 (en) * 1998-11-18 2004-02-10 Bioject, Inc. Single-use needle-less hypodermic jet injection apparatus and method
US6783509B1 (en) 1998-11-18 2004-08-31 Bioject Inc. Single-use needle-less hypodermic jet injection apparatus and method
US6264629B1 (en) 1998-11-18 2001-07-24 Bioject, Inc. Single-use needle-less hypodermic jet injection apparatus and method
DE29822494U1 (en) 1998-12-17 2000-05-04 Medico Development Investment Co., Ascona Injection device
US6036675A (en) * 1999-02-03 2000-03-14 Specialized Health Products, Inc. Safety sterile cartride unit apparatus and methods
US6090905A (en) * 1999-02-12 2000-07-18 Calgon Corporation Compositions and methods for controlling stickies
GB9903475D0 (en) 1999-02-17 1999-04-07 Owen Mumford Ltd Improvements relating to injection devices
IL128709A (en) 1999-02-24 2004-09-27 Teva Medical Ltd Fluid sampling apparatus
US6258062B1 (en) 1999-02-25 2001-07-10 Joseph M. Thielen Enclosed container power supply for a needleless injector
NO310224B1 (en) 1999-04-22 2001-06-11 Medical Needle As Disposable syringe with automatically retractable needle
US20040069044A1 (en) * 1999-04-29 2004-04-15 Gilad Lavi Device for measuring a volume of drug
SE9901736D0 (en) 1999-05-12 1999-05-12 Pharmacia & Upjohn Ab Injectino device and method for ITS operation
WO2001005456A1 (en) 1999-07-15 2001-01-25 Bracco International B.V. Plunger for syringe
IL147840A0 (en) 1999-07-27 2002-08-14 Pharma Consult Gmbh Device for automatically injecting liquids
US6162199A (en) 1999-09-20 2000-12-19 Geringer; Joseph Robert Device for loading a syringe from a vial
FR2799376B1 (en) * 1999-10-07 2002-01-18 Marc Brunel SINGLE USE INJECTION DEVICE
US6569123B2 (en) 1999-10-14 2003-05-27 Becton, Dickinson And Company Prefillable intradermal injector
US6391003B1 (en) * 1999-10-25 2002-05-21 Antares Pharma, Inc. Locking mechanism for a jet injector
US7029457B2 (en) * 1999-11-23 2006-04-18 Felton International, Inc. Jet injector with hand piece
US6595962B1 (en) 1999-12-08 2003-07-22 Union Medico Injection device
US6425885B1 (en) 1999-12-20 2002-07-30 Ultradent Products, Inc. Hydraulic syringe
US6926696B2 (en) 1999-12-23 2005-08-09 Owais Mohammed Hypodermic syringe needle assembly and method of making the same
EP1257308B1 (en) 2000-01-07 2005-06-08 Glaxo Group Limited Device for injecting a dose of liquid, in particular medicinal liquid
US6190363B1 (en) * 2000-01-24 2001-02-20 Bracco Diagnostics, Inc. Self-aligning plunger rod
GB0002095D0 (en) 2000-01-28 2000-03-22 Novartis Ag Device
US6595957B1 (en) 2000-01-31 2003-07-22 Ethicon, Inc. Surgical fluid management system with a dampening chamber
WO2001060311A1 (en) 2000-02-16 2001-08-23 B D Medico S.A.R.L. Method for reconstituting an injection liquid and an injection appliance for carrying out such a method
WO2001064266A1 (en) 2000-03-02 2001-09-07 Daikyo Seiko, Ltd. Prefilled syringe assembly
AU2001243420A1 (en) 2000-03-06 2001-09-17 Mdc Investment Holdings, Inc. Hypodermic syringe with retractable needle
US6832992B2 (en) 2000-03-07 2004-12-21 Becton, Dickinson And Company Passive safety device for needle of blood collection set
US6855130B2 (en) 2000-03-07 2005-02-15 Becton, Dickinson And Company Passive safety device for needle of IV infusion or blood collection set
GB0007071D0 (en) * 2000-03-24 2000-05-17 Sams Bernard One-way clutch mechanisms and injector devices
US6371959B1 (en) * 2000-04-05 2002-04-16 Michael E. Trice Radiolucent position locating device and drill guide
US6471677B2 (en) 2000-04-06 2002-10-29 Gem Plastics, Inc. Fluid collection device with protective shield
EP1268856A2 (en) 2000-04-07 2003-01-02 Epigenomics AG Detection of single nucleotide polymorphisms (snp's) and cytosine-methylations
GB0008955D0 (en) 2000-04-12 2000-05-31 Owen Mumford Ltd An injector pack
US6607508B2 (en) 2000-04-27 2003-08-19 Invivotech, Inc. Vial injector device
US6613022B1 (en) * 2000-05-05 2003-09-02 Safety Syringes, Inc. Passive needle guard for syringes
HU226804B1 (en) 2000-05-15 2009-10-28 Ares Trading Sa Storage container for at least one hypodermic needle
US6716198B2 (en) 2000-05-18 2004-04-06 Novo Nordisk A/S Injection device
US6740062B2 (en) 2000-05-22 2004-05-25 Pharmacia Ab Medical device
US6517517B1 (en) * 2000-06-08 2003-02-11 Mayo Foundation For Medical Education And Research Automated injection device for administration of liquid medicament
US6585690B1 (en) 2000-06-29 2003-07-01 Becton Dickinson And Company Hypodermic syringe with selectivity retractable needle
US6986760B2 (en) 2000-08-02 2006-01-17 Becton, Dickinson And Company Pen needle and safety shield system
FR2812817B1 (en) 2000-08-09 2002-10-31 Sanofi Synthelabo PROTECTION DEVICE FOR A SYRINGE NEEDLE
AU2001281753A1 (en) 2000-08-29 2002-03-13 Novo-Nordisk A/S Automatic injection device with torsion function for retraction of needle
CA2422692A1 (en) * 2000-09-21 2002-03-28 Elan Pharma International Limited Reconstitution and injection system
JP3941366B2 (en) 2000-09-22 2007-07-04 フジノン株式会社 Syringe device stopper
FR2815543B1 (en) 2000-10-19 2003-10-24 Sedat SELF-INJECTION SYRINGE OF AN EXTEMPORANEOUS MIXTURE
EP1335125B1 (en) 2000-11-17 2006-02-08 Isuzu Motors Limited Needle lift damper device of injector for fuel injection and needle lift damping method
IT1320104B1 (en) 2000-11-27 2003-11-18 Paolo Versini INJECTOR DEVICE FOR MEDICAL AND COSMETIC TREATMENTS.
US6569085B2 (en) * 2001-08-16 2003-05-27 Syntheon, Llc Methods and apparatus for delivering a medical instrument over an endoscope while the endoscope is in a body lumen
SE518981C2 (en) 2000-12-14 2002-12-17 Shl Medical Ab autoinjector
US6387078B1 (en) 2000-12-21 2002-05-14 Gillespie, Iii Richard D. Automatic mixing and injecting apparatus
US6485460B2 (en) 2001-01-12 2002-11-26 Bracco Diagnostics, Inc. Tamper evident syringe barrel
DE60212799T2 (en) 2001-01-18 2006-11-09 Medrad, Inc. SPRAY CONNECTORS AND ADAPTERS FOR USE WITH MEDICAL INJECTORS
US6811545B2 (en) 2001-01-31 2004-11-02 Vincent L. Vaillancourt Safety needle
US6673049B2 (en) * 2001-02-15 2004-01-06 Disetronic Licensing Ag Injection device for injecting fluid
GB0103977D0 (en) * 2001-02-17 2001-04-04 Owen Mumford Ltd Improvements relating to skin prickers
US6471669B2 (en) * 2001-03-05 2002-10-29 Bioject Medical Technologies Inc. Disposable needle-free injection apparatus and method
US6645170B2 (en) 2001-03-05 2003-11-11 Bioject Medical Technologies, Inc. Simplified disposable needle-free injection apparatus and method
GB0109001D0 (en) 2001-04-10 2001-05-30 Glaxo Group Ltd Dispenser
GB0109002D0 (en) 2001-04-10 2001-05-30 Glaxo Group Ltd Dispenser
EP1427463A2 (en) 2001-04-27 2004-06-16 PenJet Corporation Method and apparatus for filling or refilling a needle-less injector
US6648850B2 (en) 2001-06-08 2003-11-18 Bioject, Inc. Durable needle-less jet injector apparatus and method
DE10137962A1 (en) 2001-08-07 2003-02-20 Roesch Ag Medizintechnik Ampule for injection device for injecting medium into human or animal tissues without needle, comprising plug which closes chamber with injection medium, and is penetrated by hollow needle
CA2456969A1 (en) 2001-08-09 2003-02-27 Becton, Dickinson And Company Retracting needle safety device
GB0119520D0 (en) 2001-08-10 2001-10-03 Owen Mumford Ltd Improvements relating to injection devices
GB2391480B (en) 2002-08-05 2007-02-28 Caretek Medical Ltd Drug delivery system
US7488306B2 (en) * 2001-09-26 2009-02-10 Smiths Medical Asd, Inc. Needle protection device with dampener
AU2002353790A1 (en) 2001-10-03 2003-04-14 Medical Instill Technologies, Inc. Syringe and reconstitution syringe
FR2830765B1 (en) * 2001-10-15 2004-07-23 Plastic Omnium Cie SAFETY DEVICE FOR A SYRINGE
US6796967B2 (en) * 2001-10-22 2004-09-28 Nps Pharmaceuticals, Inc. Injection needle assembly
US7569035B1 (en) 2001-11-02 2009-08-04 Meridian Medical Technologies, Inc. Automatic injector with anti-coring needle
US6607510B2 (en) 2001-11-09 2003-08-19 Bioject Medical Technologies Inc. Disposable needle-free injection apparatus and method
ES2346049T5 (en) 2001-11-09 2014-04-02 Alza Corporation Pneumatic autoinjector
US7011649B2 (en) 2001-11-09 2006-03-14 Alza Corporation Collapsible syringe cartridge
US20030105430A1 (en) 2001-11-30 2003-06-05 Elan Pharma International Limited Wil House Automatic injector
US6863659B2 (en) 2001-12-10 2005-03-08 Bruce George Sharpe Sharp safe hydraulic retractable syringe
JP4046998B2 (en) * 2001-12-14 2008-02-13 ロレアル Applicator
EP1455869A2 (en) 2001-12-19 2004-09-15 Disetronic Licensing AG Administration device comprising an expulsion member and a stopper covering
US20040143224A1 (en) 2002-01-07 2004-07-22 Jeffrey Field Method and apparatus for inhibiting fluid loss from a syringe
GB0200444D0 (en) * 2002-01-10 2002-02-27 Owen Mumford Ltd Improvements relating to medical injection devices
AU2003209095A1 (en) * 2002-02-11 2003-09-04 Antares Pharma, Inc. Intradermal injector
DE10207276A1 (en) 2002-02-21 2003-09-11 Disetronic Licensing Ag Needle insertion device with a transversely movable holding element
GB0204673D0 (en) * 2002-02-28 2002-04-10 Dca Design Int Ltd Improvements in and relating to a medicament delivery device
GB0206560D0 (en) * 2002-03-20 2002-05-01 Glaxo Group Ltd Novel device
JP2003298253A (en) 2002-03-29 2003-10-17 Denso Corp Housing structure and mounting structure of electronic control apparatus
US6912417B1 (en) 2002-04-05 2005-06-28 Ichor Medical Systmes, Inc. Method and apparatus for delivery of therapeutic agents
US20030199814A1 (en) 2002-04-19 2003-10-23 Parsons J. Stuart Multi-component ampule
AU2002332492A1 (en) 2002-04-19 2003-11-03 Equidyne Systems, Inc. Multi-component ampule
GB2396298A (en) 2002-12-17 2004-06-23 Pa Consulting Services Injection device and drive coupling
GB2388033A (en) 2002-05-02 2003-11-05 Pa Consulting Services Automatic injection device
EP1503816B1 (en) 2002-05-02 2007-01-31 PA Consulting Services Limited Injection device
US6808507B2 (en) 2002-05-10 2004-10-26 Cambridge Biostability Ltd. Safety injectors
US7207973B2 (en) 2002-05-10 2007-04-24 Becton, Dickinson And Company Passive safety shield system for injection devices
US6776777B2 (en) 2002-05-10 2004-08-17 Becton, Dickinson And Company Passive safety shield system for injection devices
US6979316B1 (en) 2002-05-23 2005-12-27 Seedlings Life Science Ventures Llc Apparatus and method for rapid auto-injection of medication
US7156823B2 (en) * 2002-06-04 2007-01-02 Bioject Inc. High workload needle-free injection system
US6676630B2 (en) * 2002-06-04 2004-01-13 Bioject Medical Technologies, Inc. Needle-free injection system
MY139059A (en) 2002-06-24 2009-08-28 Alza Corp Reusable, spring driven autoinjector
US6764465B2 (en) 2002-06-24 2004-07-20 Long Hsiung Chen Syringe with retractable needle and safety lock
EP2286857A1 (en) 2002-07-02 2011-02-23 Panasonic Corporation Automatic administration instrument for medical use
CN1675246A (en) 2002-07-16 2005-09-28 艾金株式会社 Protein for diagnosing diabetic retinopathy
TW572761B (en) 2002-07-17 2004-01-21 Ming-Jeng Shiu Syringe with retraction force
US7097634B2 (en) 2002-07-31 2006-08-29 Alza Corporation Injection device providing automatic needle retraction
US20040087897A1 (en) 2002-07-31 2004-05-06 Birger Hjertman Device and method for liquid jet generation
US7083600B2 (en) 2002-08-08 2006-08-01 Advanced Medical Sharps, Inc. Safety needle and shield
CA2494825C (en) * 2002-08-21 2009-02-17 Pharmacia Corporation Injectable pharmaceutical suspension in a two-chamber vial
US9486581B2 (en) 2002-09-11 2016-11-08 Becton, Dickinson And Company Injector device with force lock-out and injection rate limiting mechanisms
EP1401089A1 (en) * 2002-09-18 2004-03-24 Continental ISAD Electronic Systems GmbH & Co. KG Electrical machine, formed as starter, generator or starter-generator for a vehicle
JP4448448B2 (en) 2002-09-24 2010-04-07 エス・ホー・エル・グループ・アクチボラゲット Injection device
GB0222731D0 (en) * 2002-10-01 2002-11-06 Parker David W Improvements in or relating to hypodermic syringes
GB0224505D0 (en) 2002-10-22 2002-11-27 Medical House The Plc Needles injection device
US6939319B1 (en) 2002-11-20 2005-09-06 Conrad Anstead Process and device for single use, needle-free intradermal, subcutaneous, or intramuscular injections
CH695926A5 (en) 2002-11-25 2006-10-31 Tecpharma Licensing Ag Device for automatically injecting an active ingredient.
CH696186A5 (en) 2002-11-25 2007-02-15 Tecpharma Licensing Ag Device for securing hypodermic needles.
JP2006507061A (en) 2002-11-25 2006-03-02 テクファーマ・ライセンシング・アクチェンゲゼルシャフト Automatic injection device with resettable release safety device
AU2003275893B2 (en) 2002-11-25 2008-11-13 Tecpharma Licensing Ag Device for automatically injecting an active agent
GB0229345D0 (en) 2002-12-17 2003-01-22 Safe T Ltd Hollow needle applicators
GB2396816A (en) 2002-12-17 2004-07-07 Pa Consulting Services Injection device
US7252651B2 (en) 2003-01-07 2007-08-07 Becton, Dickinson And Company Disposable injection device
US6767336B1 (en) 2003-01-09 2004-07-27 Sheldon Kaplan Automatic injector
AU2004206779B2 (en) 2003-01-22 2009-09-03 Duoject Medical Systems Inc. Pharmaceutical delivery systems and methods for using same
FR2852851B1 (en) 2003-03-25 2006-01-06 Sedat NEEDLE PROTECTION DEVICE FOR SYRINGE, AND INJECTION DEVICE COMPRISING SYRINGE AND PROTECTIVE DEVICE
JP2004305466A (en) * 2003-04-08 2004-11-04 Nipro Corp Medical connector set and catheter set for dwelling using the same
US7115114B2 (en) 2003-05-02 2006-10-03 Becton, Dickinson And Company Medical device having releasable retainer
US6805686B1 (en) 2003-05-06 2004-10-19 Abbott Laboratories Autoinjector with extendable needle protector shroud
GB0312852D0 (en) 2003-06-05 2003-07-09 Owen Mumford Ltd Improvements relating to syringe firing mechanisms
US6846030B2 (en) * 2003-06-25 2005-01-25 Ford Global Technologies, Llc Vehicle closure panel with torsion bar assist and integral vibration damping
EP1491478B1 (en) * 2003-06-25 2007-05-09 Müller Martini Holding AG Diverting device
US7500963B2 (en) 2003-07-22 2009-03-10 Safety Syringes, Inc. Systems and methods for automatic medical injection with safeguard
US20050027255A1 (en) * 2003-07-31 2005-02-03 Sid Technologies, Llc Automatic injector
DE20311996U1 (en) 2003-08-01 2003-10-16 Hoelzle Dieter Tech Projekte injection device
DE10339794A1 (en) * 2003-08-28 2005-04-07 Tecpharma Licensing Ag Administering device with a protective cap removal device and a needle protection sleeve blocking device
DE10340586A1 (en) * 2003-09-03 2005-04-07 Tecpharma Licensing Ag Mixing device for multi-chamber ampoule
DE10342058B4 (en) 2003-09-11 2007-10-25 Tecpharma Licensing Ag Administration device for an injectable product with a trigger safety device
IL157981A (en) 2003-09-17 2014-01-30 Elcam Medical Agricultural Cooperative Ass Ltd Auto-injector
FR2860162B1 (en) 2003-09-26 2006-06-02 Becton Dickinson France DEVICE FOR PROTECTING AN INJECTION APPARATUS
AU2004279651B2 (en) 2003-10-16 2010-07-08 Tecpharma Licensing Ag Injection device for administering a fluid product
DE10348185A1 (en) * 2003-10-16 2005-05-19 Tecpharma Licensing Ag Injection device for administering fluid product e.g. insulin, comprising injection needle and needle cover arranged on holder or on casing so that it can shift and generally surrounds injection needle in advanced position
US20050085776A1 (en) * 2003-10-16 2005-04-21 Edgar Hommann Injection device for administering a fluid product
JP2005141729A (en) 2003-10-17 2005-06-02 Fuji Xerox Co Ltd Method, device, and program for peripheral apparatus and control and method, device, and program for display control
FR2861310B1 (en) 2003-10-22 2006-09-22 Plastef Investissements SECURE INJECTION SYRINGE DEVICE
DE10351598A1 (en) 2003-11-05 2005-06-16 Tecpharma Licensing Ag Auto-injection device
US20050101919A1 (en) 2003-11-07 2005-05-12 Lennart Brunnberg Device for an injector
US20050125019A1 (en) 2003-12-05 2005-06-09 Paul Kudrna Lancet device and method
AU2004298302B2 (en) 2003-12-18 2009-04-02 Tecpharma Licensing Ag Releasable injection device
CH696421A5 (en) 2003-12-18 2007-06-15 Tecpharma Licensing Ag Autoinjector with arresting the drug container.
US20050137523A1 (en) 2003-12-22 2005-06-23 Wyatt Philip W. Medicament administration apparatus
WO2005070481A1 (en) 2004-01-23 2005-08-04 The Medical House Plc Injection device
FR2865407B1 (en) 2004-01-27 2006-04-28 Crossject NEEDLELESS SYRINGE WITH INJECTOR RECEPTACLE AMORTISSANT
US20050209554A1 (en) 2004-03-19 2005-09-22 Sergio Landau Needle-free single-use cartridge and injection system
US20050222539A1 (en) 2004-03-30 2005-10-06 Pediamed Pharmaceuticals, Inc. Automatic injection device
US20050261633A1 (en) 2004-05-19 2005-11-24 Khalaj Ben M Rechargeable handheld injection device with reversible drive having adjustable syringe cradle
GB2414409B (en) 2004-05-28 2009-11-18 Cilag Ag Int Injection device
GB2414403B (en) 2004-05-28 2009-01-07 Cilag Ag Int Injection device
GB2414402B (en) 2004-05-28 2009-04-22 Cilag Ag Int Injection device
GB2414401B (en) 2004-05-28 2009-06-17 Cilag Ag Int Injection device
GB2414400B (en) 2004-05-28 2009-01-14 Cilag Ag Int Injection device
GB2414398B (en) 2004-05-28 2009-04-22 Cilag Ag Int Injection device
GB2414406B (en) 2004-05-28 2009-03-18 Cilag Ag Int Injection device
GB2414399B (en) 2004-05-28 2008-12-31 Cilag Ag Int Injection device
WO2005115514A1 (en) 2004-05-28 2005-12-08 Cilag Gmbh International Injection device
US20050273054A1 (en) 2004-06-03 2005-12-08 Florida Atlantic University Epinephrine auto-injector
US20060100588A1 (en) 2004-07-23 2006-05-11 Lennart Brunnberg Needle handling device
US7449012B2 (en) 2004-08-06 2008-11-11 Meridian Medical Technologies, Inc. Automatic injector
US20060069350A1 (en) * 2004-09-30 2006-03-30 Buenger David R Medical syringe injector pen
US7731678B2 (en) 2004-10-13 2010-06-08 Hyprotek, Inc. Syringe devices and methods for mixing and administering medication
US20060089593A1 (en) 2004-10-26 2006-04-27 Sergio Landau Needle-free injection device for individual users
US20060089594A1 (en) 2004-10-26 2006-04-27 Sergio Landau Needle-free injection device
US7255689B2 (en) 2004-10-29 2007-08-14 Safety Syringes, Inc. Syringe with anti-rotation for luer lock
US7412273B2 (en) 2004-11-15 2008-08-12 Biosense Webster, Inc. Soft linear mapping catheter with stabilizing tip
US7905352B2 (en) 2004-12-06 2011-03-15 Washington Biotech Corporation Kits containing medicine injection devices and containers
US7297136B2 (en) 2004-12-06 2007-11-20 Wyrick Ronald E Medicine injection devices and methods
JP2008522754A (en) 2004-12-09 2008-07-03 ウェスト ファーマシューティカル サービシズ インコーポレイテッド Retrofit type fixed needle syringe and automatic injection apparatus having the same
US20060258986A1 (en) 2005-02-11 2006-11-16 Hunter Ian W Controlled needle-free transport
US20070060904A1 (en) 2005-03-14 2007-03-15 Becton, Dickinson And Company Filling system and method for syringes with short needles
GB2425062B (en) 2005-04-06 2010-07-21 Cilag Ag Int Injection device
GB2424838B (en) 2005-04-06 2011-02-23 Cilag Ag Int Injection device (adaptable drive)
GB2424835B (en) 2005-04-06 2010-06-09 Cilag Ag Int Injection device (modified trigger)
GB2424836B (en) 2005-04-06 2010-09-22 Cilag Ag Int Injection device (bayonet cap removal)
GB2424837B (en) 2005-04-06 2010-10-06 Cilag Ag Int Injection device
FR2884721A1 (en) 2005-04-20 2006-10-27 Becton Dickinson France Soc Pa Assistance device for device of injection of a product, comprises hollow body for receiving the product, hollow injection needle for penetrating into injection site, piston placed in the body, hollow sleeve with bearing surface
US7699802B2 (en) 2005-05-03 2010-04-20 Pharmajet, Inc. Needle-less injector
US20070015134A1 (en) * 2005-07-15 2007-01-18 Beckman Coulter, Inc. Quantitative stabilized cell reference control products and methods
US20110098656A1 (en) 2005-09-27 2011-04-28 Burnell Rosie L Auto-injection device with needle protecting cap having outer and inner sleeves
AU2006304009A1 (en) 2005-10-11 2007-04-26 Eli Lilly And Company Apparatus for injecting a pharmaceutical
DE102005052502A1 (en) 2005-11-03 2007-05-16 Tecpharma Licensing Ag Auto-injector activation trigger element
GB2433032A (en) 2005-12-08 2007-06-13 Owen Mumford Ltd Syringe with dose adjustment means
WO2007122193A1 (en) 2006-04-21 2007-11-01 Novo Nordisk A/S Two stage jet injection device
GB2465919B (en) 2006-05-10 2010-12-08 Owen Mumford Ltd Injection device with cap that can be re-fitted post injection
GB2438629B (en) 2006-06-01 2011-02-23 Cilag Gmbh Int Injection device
GB2438590B (en) 2006-06-01 2011-02-09 Cilag Gmbh Int Injection device
GB2438591B (en) 2006-06-01 2011-07-13 Cilag Gmbh Int Injection device
US20080020979A1 (en) * 2006-06-09 2008-01-24 Rapraeger Alan C Peptides of Syndecan-1 For Inhibiting Angiogenesis
WO2008047372A2 (en) 2006-10-19 2008-04-24 Elcam Medical Agricultural Cooperative Association Ltd. Automatic injection device
DK1932558T3 (en) 2006-12-13 2011-09-05 Shl Group Ab autoinjector
GB2446778A (en) 2007-02-01 2008-08-27 Pa Knowledge Ltd Syringe adaptor
EP2121083A2 (en) 2007-02-01 2009-11-25 PA Knowledge Limited Auto injector and adaptor for covering the needle of the auto injector
WO2008113864A1 (en) 2007-03-22 2008-09-25 Tecpharma Licensing Ag Injection device having trigger safety devices

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US8317751B2 (en) 2012-11-27
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CA2603664A1 (en) 2006-10-12
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