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EP2341831A4 - Profiling method useful for condition diagnosis and monitoring, composition screening, and therapeutic monitoring - Google Patents

Profiling method useful for condition diagnosis and monitoring, composition screening, and therapeutic monitoring

Info

Publication number
EP2341831A4
EP2341831A4 EP20090815128 EP09815128A EP2341831A4 EP 2341831 A4 EP2341831 A4 EP 2341831A4 EP 20090815128 EP20090815128 EP 20090815128 EP 09815128 A EP09815128 A EP 09815128A EP 2341831 A4 EP2341831 A4 EP 2341831A4
Authority
EP
European Patent Office
Prior art keywords
monitoring
method useful
condition diagnosis
profiling method
therapeutic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP20090815128
Other languages
German (de)
French (fr)
Other versions
EP2341831A1 (en
Inventor
Jonathan B Chaires
Nichola C Garbett
Albert S Benight
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Louisville Research Foundation ULRF
Louisville Bioscience Inc
Original Assignee
University of Louisville Research Foundation ULRF
Louisville Bioscience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Louisville Research Foundation ULRF, Louisville Bioscience Inc filed Critical University of Louisville Research Foundation ULRF
Publication of EP2341831A1 publication Critical patent/EP2341831A1/en
Publication of EP2341831A4 publication Critical patent/EP2341831A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00Methods of screening libraries
    • C40B30/06Methods of screening libraries by measuring effects on living organisms, tissues or cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/62Detectors specially adapted therefor
    • G01N30/72Mass spectrometers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/56Staging of a disease; Further complications associated with the disease

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP20090815128 2008-09-16 2009-09-16 Profiling method useful for condition diagnosis and monitoring, composition screening, and therapeutic monitoring Withdrawn EP2341831A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9743308P 2008-09-16 2008-09-16
PCT/US2009/057172 WO2010033606A1 (en) 2008-09-16 2009-09-16 Profiling method useful for condition diagnosis and monitoring, composition screening, and therapeutic monitoring

Publications (2)

Publication Number Publication Date
EP2341831A1 EP2341831A1 (en) 2011-07-13
EP2341831A4 true EP2341831A4 (en) 2012-05-30

Family

ID=42039843

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20090815128 Withdrawn EP2341831A4 (en) 2008-09-16 2009-09-16 Profiling method useful for condition diagnosis and monitoring, composition screening, and therapeutic monitoring

Country Status (5)

Country Link
EP (1) EP2341831A4 (en)
KR (1) KR20110086802A (en)
AU (1) AU2009293289A1 (en)
CA (1) CA2737408A1 (en)
WO (1) WO2010033606A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12487200B2 (en) 2019-10-24 2025-12-02 University Of Louisville Research Foundation, Inc. Microfabricated differential scanning calorimetry system and methods of use thereof
US11835529B1 (en) 2019-10-24 2023-12-05 University Of Louisville Research Foundation, Inc. Plasma thermograms for diagnosis and treatment of acute myocardial infarction
US12442736B1 (en) 2019-10-24 2025-10-14 University Of Louisville Research Foundation, Inc. Microfluidic manifold and methods of use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070157325A1 (en) * 2005-12-30 2007-07-05 Shahriar Mojtahedian Process for identification of novel disease biomarkers in mouse models of alzheimer's disease including triple transgenic mice and products thereby
KR20090105967A (en) * 2007-01-12 2009-10-07 유니버시티 오브 루이빌 리서치 파운데이션, 인코포레이티드 Proteome Profiling Methods Useful for Disease Diagnosis and Monitoring, Composition Screening, and Treatment Monitoring

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
HERNANDEZ-HERNANDEZ A ET AL: "Alterations in erythrocyte membrane protein composition in advanced non-small cell lung cancer", BLOOD CELLS, MOLECULES AND DISEASES, LAJOLLA, US, vol. 36, no. 3, 6 May 2006 (2006-05-06), pages 355 - 363, XP024917772, ISSN: 1079-9796, [retrieved on 20060506], DOI: 10.1016/J.BCMD.2006.02.002 *
IVANOV ANDREI I ET AL: "Dramatic irreversible changes of human serum albumin structure in liver cirrhosis", 1 January 2006, NEW DEVELOPMENTS IN LIVER CIRRHOSIS RESEARCH, NOVA-BIOMEDICAL, US, PAGE(S) 103 - 122, ISBN: 978-1-59454-355-5, XP009127788 *
ROGALINSKA MALGORZATA ET AL: "Changes in leukemic cell nuclei revealed by differential scanning calorimetry", LEUKEMIA AND LYMPHOMA, HARWOOD ACADEMIC PUBLISHERS, CHUR, CH, vol. 46, no. 1, 1 January 2005 (2005-01-01), pages 121 - 128, XP009127750, ISSN: 1042-8194, DOI: 10.1080/10428190412331283170 *
See also references of WO2010033606A1 *

Also Published As

Publication number Publication date
WO2010033606A1 (en) 2010-03-25
AU2009293289A1 (en) 2010-03-25
CA2737408A1 (en) 2010-03-25
KR20110086802A (en) 2011-08-01
EP2341831A1 (en) 2011-07-13

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 20110408

AK Designated contracting states

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Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR

AX Request for extension of the european patent

Extension state: AL BA RS

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20120426

RIC1 Information provided on ipc code assigned before grant

Ipc: G01N 33/68 20060101AFI20120420BHEP

Ipc: G01N 25/48 20060101ALI20120420BHEP

17Q First examination report despatched

Effective date: 20130603

STAA Information on the status of an ep patent application or granted ep patent

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18D Application deemed to be withdrawn

Effective date: 20150731