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EP2093245A3 - Dispositif biocompatible à base de polymère - Google Patents

Dispositif biocompatible à base de polymère Download PDF

Info

Publication number
EP2093245A3
EP2093245A3 EP09004765A EP09004765A EP2093245A3 EP 2093245 A3 EP2093245 A3 EP 2093245A3 EP 09004765 A EP09004765 A EP 09004765A EP 09004765 A EP09004765 A EP 09004765A EP 2093245 A3 EP2093245 A3 EP 2093245A3
Authority
EP
European Patent Office
Prior art keywords
biocompatible polymer
polymer device
polyethylene glycol
relates generally
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP09004765A
Other languages
German (de)
English (en)
Other versions
EP2093245A2 (fr
EP2093245B1 (fr
Inventor
Donald G. Wallace
George H. Chu
Jacqueline Anne Schroeder
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Angiodevice International GmbH
Original Assignee
Angiodevice International GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angiodevice International GmbH filed Critical Angiodevice International GmbH
Publication of EP2093245A2 publication Critical patent/EP2093245A2/fr
Publication of EP2093245A3 publication Critical patent/EP2093245A3/fr
Application granted granted Critical
Publication of EP2093245B1 publication Critical patent/EP2093245B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0031—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0015—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0026—Sprayable compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/046—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G75/00—Macromolecular compounds obtained by reactions forming a linkage containing sulfur with or without nitrogen, oxygen, or carbon in the main chain of the macromolecule
    • C08G75/02—Polythioethers
    • C08G75/04—Polythioethers from mercapto compounds or metallic derivatives thereof
    • C08G75/045—Polythioethers from mercapto compounds or metallic derivatives thereof from mercapto compounds and unsaturated compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G75/00—Macromolecular compounds obtained by reactions forming a linkage containing sulfur with or without nitrogen, oxygen, or carbon in the main chain of the macromolecule
    • C08G75/26—Polythioesters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L81/00—Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing sulfur with or without nitrogen, oxygen or carbon only; Compositions of polysulfones; Compositions of derivatives of such polymers
    • C08L81/02—Polythioethers; Polythioether-ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/418—Agents promoting blood coagulation, blood-clotting agents, embolising agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/914—Protein engineering

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Polymerisation Methods In General (AREA)
EP09004765A 1999-08-27 2000-08-28 Dispositif biocompatible à base de polymère Expired - Lifetime EP2093245B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15127399P 1999-08-27 1999-08-27
EP00959535A EP1218437B1 (fr) 1999-08-27 2000-08-28 Compositions formant des reseaux de polymeres interpenetrants, a utiliser en tant produits de scellement medicaux a haute resistance

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
EP00959535.6 Division 2000-08-28
EP00959535A Division EP1218437B1 (fr) 1999-08-27 2000-08-28 Compositions formant des reseaux de polymeres interpenetrants, a utiliser en tant produits de scellement medicaux a haute resistance

Publications (3)

Publication Number Publication Date
EP2093245A2 EP2093245A2 (fr) 2009-08-26
EP2093245A3 true EP2093245A3 (fr) 2009-09-09
EP2093245B1 EP2093245B1 (fr) 2012-02-22

Family

ID=22538029

Family Applications (2)

Application Number Title Priority Date Filing Date
EP09004765A Expired - Lifetime EP2093245B1 (fr) 1999-08-27 2000-08-28 Dispositif biocompatible à base de polymère
EP00959535A Expired - Lifetime EP1218437B1 (fr) 1999-08-27 2000-08-28 Compositions formant des reseaux de polymeres interpenetrants, a utiliser en tant produits de scellement medicaux a haute resistance

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP00959535A Expired - Lifetime EP1218437B1 (fr) 1999-08-27 2000-08-28 Compositions formant des reseaux de polymeres interpenetrants, a utiliser en tant produits de scellement medicaux a haute resistance

Country Status (10)

Country Link
US (1) US6495127B1 (fr)
EP (2) EP2093245B1 (fr)
JP (3) JP2003508564A (fr)
AT (2) ATE434010T1 (fr)
AU (1) AU7084300A (fr)
DE (1) DE60042414D1 (fr)
DK (2) DK2093245T3 (fr)
ES (1) ES2383122T3 (fr)
PT (1) PT2093245E (fr)
WO (1) WO2001016210A1 (fr)

Families Citing this family (231)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6241747B1 (en) 1993-05-03 2001-06-05 Quill Medical, Inc. Barbed Bodily tissue connector
US8795332B2 (en) 2002-09-30 2014-08-05 Ethicon, Inc. Barbed sutures
US6833408B2 (en) * 1995-12-18 2004-12-21 Cohesion Technologies, Inc. Methods for tissue repair using adhesive materials
US7883693B2 (en) 1995-12-18 2011-02-08 Angiodevice International Gmbh Compositions and systems for forming crosslinked biomaterials and methods of preparation of use
PT1704878E (pt) 1995-12-18 2013-07-17 Angiodevice Internat Gmbh Composições de polímeros reticulados e métodos para a sua utilização
US6458889B1 (en) * 1995-12-18 2002-10-01 Cohesion Technologies, Inc. Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use
US8003705B2 (en) 1996-09-23 2011-08-23 Incept Llc Biocompatible hydrogels made with small molecule precursors
US5931855A (en) 1997-05-21 1999-08-03 Frank Hoffman Surgical methods using one-way suture
US6899889B1 (en) 1998-11-06 2005-05-31 Neomend, Inc. Biocompatible material composition adaptable to diverse therapeutic indications
US6830756B2 (en) 1998-11-06 2004-12-14 Neomend, Inc. Systems, methods, and compositions for achieving closure of vascular puncture sites
EP1137373A4 (fr) 1998-12-04 2004-05-19 Chandrashekhar P Pathak Polymeres reticules biocompatibles
EP1263803B1 (fr) 2000-03-13 2007-09-19 BioCure, Inc. Compositions anti-embolie
US6652883B2 (en) 2000-03-13 2003-11-25 Biocure, Inc. Tissue bulking and coating compositions
US20050165428A1 (en) * 2000-09-25 2005-07-28 Franco Kenneth L. Absorable surgical structure
CA2423061A1 (fr) * 2000-09-25 2002-03-28 Cohesion Technologies, Inc. Stents et obturateurs anastomotiques resorbables et leur utilisation chez des patients
DK1328300T3 (da) * 2000-10-23 2005-03-21 Tissuemed Ltd Selvklæbende hydratiserbar matrix til topisk terapeutisk anvendelse
WO2002076285A2 (fr) * 2001-03-23 2002-10-03 Histogenics Corporation Composition et methodes de production de tissus biologiques et de constructions tissulaires
US7056331B2 (en) 2001-06-29 2006-06-06 Quill Medical, Inc. Suture method
CA2689916C (fr) * 2001-07-31 2013-02-12 Tyco Healthcare Group Lp Compose et compositions adhesifs bioabsorbables
US6848152B2 (en) 2001-08-31 2005-02-01 Quill Medical, Inc. Method of forming barbs on a suture and apparatus for performing same
US6863678B2 (en) 2001-09-19 2005-03-08 Advanced Cardiovascular Systems, Inc. Catheter with a multilayered shaft section having a polyimide layer
US6773699B1 (en) * 2001-10-09 2004-08-10 Tissue Adhesive Technologies, Inc. Light energized tissue adhesive conformal patch
US6939364B1 (en) * 2001-10-09 2005-09-06 Tissue Adhesive Technologies, Inc. Composite tissue adhesive
US6780840B1 (en) * 2001-10-09 2004-08-24 Tissue Adhesive Technologies, Inc. Method for making a light energized tissue adhesive
US6875427B1 (en) * 2001-10-09 2005-04-05 Tissue Adhesive Technologies, Inc. Light energized tissue adhesive
AU2002363343B2 (en) * 2001-11-07 2008-07-24 Eidgenossische Technische Hochschule Zurich Synthetic matrix for controlled cell ingrowth and tissue regeneration
US7037291B2 (en) * 2001-12-04 2006-05-02 Advanced Cardiovascular Systems, Inc. Catheter shaft junction having a polymeric reinforcing member with a high glass transition temperature
US7923431B2 (en) 2001-12-21 2011-04-12 Ferrosan Medical Devices A/S Haemostatic kit, a method of preparing a haemostatic agent and a method of promoting haemostatis
EP1469893A1 (fr) * 2002-02-01 2004-10-27 Sustech GmbH & Co. KG Prepolymeres en etoile pour la production de revetements ultraminces formant des hydrogels
US8282912B2 (en) 2002-03-22 2012-10-09 Kuros Biosurgery, AG Compositions for tissue augmentation
US6773450B2 (en) 2002-08-09 2004-08-10 Quill Medical, Inc. Suture anchor and method
US7846141B2 (en) 2002-09-03 2010-12-07 Bluesky Medical Group Incorporated Reduced pressure treatment system
US20040088003A1 (en) 2002-09-30 2004-05-06 Leung Jeffrey C. Barbed suture in combination with surgical needle
US8100940B2 (en) 2002-09-30 2012-01-24 Quill Medical, Inc. Barb configurations for barbed sutures
GB0224986D0 (en) 2002-10-28 2002-12-04 Smith & Nephew Apparatus
JP4809605B2 (ja) * 2002-10-28 2011-11-09 タイコ ヘルスケア グループ エルピー 生体吸収性接着剤化合物
CN1739017B (zh) 2002-12-11 2011-04-06 弗罗桑医疗设备公司 用作拭子的基于明胶的材料
JP4585743B2 (ja) * 2003-02-13 2010-11-24 独立行政法人物質・材料研究機構 生体内分解吸収性粘着性医用材料
ATE455563T1 (de) 2003-04-04 2010-02-15 Tissuemed Ltd Zusammensetzungen für die gewebeadhäsion
US7624487B2 (en) 2003-05-13 2009-12-01 Quill Medical, Inc. Apparatus and method for forming barbs on a suture
US20050090804A1 (en) * 2003-10-22 2005-04-28 Trivascular, Inc. Endoluminal prosthesis endoleak management
US20050148512A1 (en) * 2003-11-10 2005-07-07 Angiotech International Ag Medical implants and fibrosis-inducing agents
US20050100712A1 (en) * 2003-11-12 2005-05-12 Simmons Blake A. Polymerization welding and application to microfluidics
US20050125033A1 (en) * 2003-12-04 2005-06-09 Mcnally-Heintzelman Karen M. Wound closure apparatus
US7384984B2 (en) * 2003-12-10 2008-06-10 3M Innovative Properties Company Reactive hydrophilic oligomers
JP4912565B2 (ja) * 2003-12-15 2012-04-11 独立行政法人物質・材料研究機構 生体内分解吸収性粘着性医用材料
DE602005022554D1 (de) 2004-01-30 2010-09-09 Ferrosan As Hämostatische sprays und zusammensetzungen
US7909805B2 (en) 2004-04-05 2011-03-22 Bluesky Medical Group Incorporated Flexible reduced pressure treatment appliance
US10058642B2 (en) 2004-04-05 2018-08-28 Bluesky Medical Group Incorporated Reduced pressure treatment system
US8062272B2 (en) 2004-05-21 2011-11-22 Bluesky Medical Group Incorporated Flexible reduced pressure treatment appliance
GB0409446D0 (en) 2004-04-28 2004-06-02 Smith & Nephew Apparatus
KR100974733B1 (ko) * 2004-04-28 2010-08-06 안지오디바이스 인터내셔널 게엠베하 가교된 생합성물질을 형성하기 위한 조성물 및 시스템, 및이와 관련된 제조 및 사용 방법
SG164370A1 (en) 2004-05-14 2010-09-29 Quill Medical Inc Suture methods and devices
US20050281866A1 (en) * 2004-05-24 2005-12-22 Genzyme Corporation Adherent polymeric compositions
US7282584B2 (en) 2004-06-16 2007-10-16 Straumann Holding Ag Methylene blue
EP1609491B1 (fr) 2004-06-16 2008-02-06 Straumann Holding AG Membrane barrière
WO2006004941A2 (fr) 2004-06-29 2006-01-12 Biocure, Inc. Biomateriel
US8021684B2 (en) 2004-07-09 2011-09-20 Ferrosan Medical Devices A/S Haemostatic composition comprising hyaluronic acid
EP1793873B1 (fr) * 2004-08-03 2013-08-07 Tissuemed Limited Materiaux adhesifs tissulaires
WO2006034128A2 (fr) 2004-09-17 2006-03-30 Angiotech Biomaterials Corporation Composes multifonctionels pour la formation de biomateriaux reticules et leurs procedes de preparation et d'utilisation
US8790632B2 (en) 2004-10-07 2014-07-29 Actamax Surgical Materials, Llc Polymer-based tissue-adhesive form medical use
JP4975627B2 (ja) * 2004-10-07 2012-07-11 アクタマックス サージカル マテリアルズ リミテッド ライアビリティ カンパニー 医療用途のための多糖ベースのポリマー組織接着剤
US20060159650A1 (en) * 2005-01-14 2006-07-20 Bacterin, Inc. Composition and method for covalently coupling an antithrombotic substance and a hydrophilic polymer
AU2006213822B2 (en) 2005-02-09 2011-05-26 Covidien Lp Synthetic sealants
US20060222596A1 (en) 2005-04-01 2006-10-05 Trivascular, Inc. Non-degradable, low swelling, water soluble radiopaque hydrogel polymer
US20060247789A1 (en) * 2005-04-29 2006-11-02 Sdgi Holdings, Inc. Method and device for stabilization of prosthetic devices
US8044234B2 (en) * 2005-05-05 2011-10-25 Tyco Healthcare Group Lp Bioabsorbable surgical composition
US20090177226A1 (en) * 2005-05-05 2009-07-09 Jon Reinprecht Bioabsorbable Surgical Compositions
US20100100124A1 (en) * 2005-05-05 2010-04-22 Tyco Healthcare Group Lp Bioabsorbable surgical composition
US8679537B2 (en) 2005-08-24 2014-03-25 Actamaz Surgical Materials, LLC Methods for sealing an orifice in tissue using an aldol-crosslinked polymeric hydrogel adhesive
US8679536B2 (en) 2005-08-24 2014-03-25 Actamax Surgical Materials, Llc Aldol-crosslinked polymeric hydrogel adhesives
RU2472809C2 (ru) * 2005-09-02 2013-01-20 Колбар Лайфсайенс Лтд. Поперечно сшитые полисахаридные и белковые матрицы и способы их получения
AU2006321914B2 (en) * 2005-12-06 2012-01-19 Covidien Lp Bioabsorbable compounds and compositions containing them
US7947263B2 (en) 2005-12-06 2011-05-24 Tyco Healthcare Group Lp Biocompatible surgical compositions
AU2006321912B2 (en) 2005-12-06 2012-07-12 Covidien Lp Carbodiimide crosslinking of functionalized polethylene glycols
AU2006321913B2 (en) 2005-12-06 2012-08-02 Covidien Lp Biocompatible tissue sealants and adhesives
AU2006321915B2 (en) 2005-12-06 2012-04-26 Covidien Lp Bioabsorbable surgical composition
JP2009518142A (ja) 2005-12-08 2009-05-07 タイコ ヘルスケア グループ リミテッド パートナーシップ 生体適合性外科用組成物
US8690957B2 (en) 2005-12-21 2014-04-08 Warsaw Orthopedic, Inc. Bone graft composition, method and implant
US9393344B2 (en) * 2006-01-11 2016-07-19 Hyperbranch Medical Technology, Inc. Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices
US20100227804A1 (en) * 2006-01-18 2010-09-09 The University Of Tokyo Gel-forming composition for medical use, administration device for the composition, and drug release controlling carrier
CA2573472A1 (fr) * 2006-01-23 2007-07-23 Tyco Healthcare Group Lp Compositions hemostatiques biodegradables
WO2007088402A2 (fr) 2006-02-03 2007-08-09 Tissuemed Limited Materiaux d'adhérence tissulaire
EP1986709B8 (fr) 2006-02-14 2017-10-18 Cook Medical Technologies LLC Jonction et/ou collage de tissus par réticulation photo-activée de protéines matricielles
US20070233219A1 (en) * 2006-02-16 2007-10-04 Bilal Shafi Polymeric heart restraint
JP5503148B2 (ja) * 2006-02-22 2014-05-28 コヴィディエン リミテッド パートナーシップ 生分解性リン酸エステルポリアミン
US20090018575A1 (en) * 2006-03-01 2009-01-15 Tissuemed Limited Tissue-adhesive formulations
US8795709B2 (en) 2006-03-29 2014-08-05 Incept Llc Superabsorbent, freeze dried hydrogels for medical applications
CA2650473C (fr) 2006-04-24 2013-06-18 Incept, Llc Agents de reticulation de proteine, methodes de reticulation et leurs applications
US7872068B2 (en) 2006-05-30 2011-01-18 Incept Llc Materials formable in situ within a medical device
US8382738B2 (en) 2006-06-30 2013-02-26 Abbott Cardiovascular Systems, Inc. Balloon catheter tapered shaft having high strength and flexibility and method of making same
US7906066B2 (en) 2006-06-30 2011-03-15 Abbott Cardiovascular Systems, Inc. Method of making a balloon catheter shaft having high strength and flexibility
US8685421B2 (en) 2006-07-07 2014-04-01 Surmodics, Inc. Beaded wound spacer device
US7732190B2 (en) * 2006-07-31 2010-06-08 Advanced Cardiovascular Systems, Inc. Modified two-component gelation systems, methods of use and methods of manufacture
TWI436793B (zh) 2006-08-02 2014-05-11 Baxter Int 快速作用之乾密封膠及其使用和製造方法
US9005672B2 (en) 2006-11-17 2015-04-14 Abbott Cardiovascular Systems Inc. Methods of modifying myocardial infarction expansion
ES2381639T3 (es) 2007-04-13 2012-05-30 Kuros Biosurgery Ag Sellante polimérico para tejidos
US20080255612A1 (en) 2007-04-13 2008-10-16 Angiotech Pharmaceuticals, Inc. Self-retaining systems for surgical procedures
US20110123476A1 (en) * 2007-05-24 2011-05-26 Mbiya Kapiamba Adhesive Formulations
US20080293910A1 (en) * 2007-05-24 2008-11-27 Tyco Healthcare Group Lp Adhesive formulatiions
US7858835B2 (en) 2007-06-27 2010-12-28 Tyco Healthcare Group Lp Foam control for synthetic adhesive/sealant
US9125807B2 (en) 2007-07-09 2015-09-08 Incept Llc Adhesive hydrogels for ophthalmic drug delivery
ES2398779T3 (es) 2007-09-27 2013-03-21 Ethicon Llc Suturas de auto-retención que incluyen elementos de retención a tejido con resistencia mejorada
US8500947B2 (en) 2007-11-15 2013-08-06 Covidien Lp Speeding cure rate of bioadhesives
ES2715605T3 (es) 2007-11-21 2019-06-05 Smith & Nephew Apósito para heridas
GB0722820D0 (en) 2007-11-21 2008-01-02 Smith & Nephew Vacuum assisted wound dressing
WO2009067711A2 (fr) 2007-11-21 2009-05-28 T.J. Smith & Nephew, Limited Dispositif d'aspiration et habillage
GB0723875D0 (en) 2007-12-06 2008-01-16 Smith & Nephew Wound management
US20130096518A1 (en) 2007-12-06 2013-04-18 Smith & Nephew Plc Wound filling apparatuses and methods
US11253399B2 (en) 2007-12-06 2022-02-22 Smith & Nephew Plc Wound filling apparatuses and methods
US8403885B2 (en) 2007-12-17 2013-03-26 Abbott Cardiovascular Systems Inc. Catheter having transitioning shaft segments
US8299316B2 (en) 2007-12-18 2012-10-30 Ethicon, Inc. Hemostatic device
US8629314B2 (en) 2007-12-18 2014-01-14 Ethicon, Inc. Surgical barriers having adhesion inhibiting properties
JP5518737B2 (ja) 2007-12-19 2014-06-11 エシコン・エルエルシー 熱接触媒介リテーナを備えた留置縫合糸
US8916077B1 (en) 2007-12-19 2014-12-23 Ethicon, Inc. Self-retaining sutures with retainers formed from molten material
US8118834B1 (en) 2007-12-20 2012-02-21 Angiotech Pharmaceuticals, Inc. Composite self-retaining sutures and method
ES2602570T3 (es) 2008-01-30 2017-02-21 Ethicon Llc Aparato y método para formar suturas de auto-retención
US8615856B1 (en) 2008-01-30 2013-12-31 Ethicon, Inc. Apparatus and method for forming self-retaining sutures
JP5644036B2 (ja) * 2008-02-08 2014-12-24 三菱レイヨン株式会社 ハイドロゲルおよびその製造方法
WO2009105663A2 (fr) 2008-02-21 2009-08-27 Angiotech Pharmaceuticals, Inc. Procédé et appareil permettant de relever des éléments de rétention sur des sutures autorétentives
US8216273B1 (en) 2008-02-25 2012-07-10 Ethicon, Inc. Self-retainers with supporting structures on a suture
US8641732B1 (en) 2008-02-26 2014-02-04 Ethicon, Inc. Self-retaining suture with variable dimension filament and method
GB0803564D0 (en) 2008-02-27 2008-04-02 Smith & Nephew Fluid collection
RU2545810C2 (ru) 2008-02-29 2015-04-10 Ферросан Медикал Дивайсиз А/С Устройство для ускорения остановки кровотечения и/или заживления ран
US8128983B2 (en) 2008-04-11 2012-03-06 Abbott Cardiovascular Systems Inc. Coating comprising poly(ethylene glycol)-poly(lactide-glycolide-caprolactone) interpenetrating network
BRPI0911132B8 (pt) 2008-04-15 2021-06-22 Angiotech Pharm Inc sutura para ser usada em um procedimento aplicado ao tecido
CA2722092C (fr) * 2008-04-22 2016-07-12 Angiotech Pharmaceuticals, Inc. Hydrogels reticules biocompatibles, hydrogels charges de medicaments et leurs procedes d'utilisation
US8263704B2 (en) 2008-04-23 2012-09-11 Tyco Healthcare Group Lp Bioabsorbable surgical composition
WO2009136824A1 (fr) * 2008-05-06 2009-11-12 Calignum Technologies Ab Imprégnation du bois à l'aide de mélanges de polymérisation thiol-ène
US8961560B2 (en) 2008-05-16 2015-02-24 Ethicon, Inc. Bidirectional self-retaining sutures with laser-marked and/or non-laser marked indicia and methods
EP3420923A1 (fr) 2008-11-03 2019-01-02 Ethicon, LLC Longueur de suture autorétentive et son dispositif d'utilisation
CN102361655B (zh) 2008-11-19 2016-08-03 阿克塔马克斯手术器材有限责任公司 纤维组织封合剂及其使用方法
US8052638B2 (en) 2008-11-26 2011-11-08 Abbott Cardiovascular Systems, Inc. Robust multi-layer balloon
US8444608B2 (en) 2008-11-26 2013-05-21 Abbott Cardivascular Systems, Inc. Robust catheter tubing
JP5706691B2 (ja) * 2008-12-19 2015-04-22 株式会社ネクスト２１ ハイドロゲルの製造方法，及びハイドロゲル
AU2010213612B2 (en) 2009-02-12 2015-04-30 Incept, Llc Drug delivery through hydrogel plugs
GB0902816D0 (en) 2009-02-19 2009-04-08 Smith & Nephew Fluid communication path
US8349987B2 (en) 2009-02-19 2013-01-08 Covidien Lp Adhesive formulations
US20100226959A1 (en) * 2009-03-04 2010-09-09 Warsaw Orthopedic, Inc. Matrix that prolongs growth factor release
WO2010129510A2 (fr) 2009-05-04 2010-11-11 Incept. Llc Biomatériaux pour la fermeture de voie et de ponction
US9463260B2 (en) * 2009-06-29 2016-10-11 Covidien Lp Self-sealing compositions
WO2011079336A1 (fr) * 2009-12-16 2011-07-07 Baxter International Inc. Eponge hémostatique
SA111320355B1 (ar) 2010-04-07 2015-01-08 Baxter Heathcare S A إسفنجة لايقاف النزف
EP2380920A1 (fr) * 2010-04-22 2011-10-26 QGel SA Formulation de précurseur d'hydrogel et son procédé de fabrication
US9061095B2 (en) 2010-04-27 2015-06-23 Smith & Nephew Plc Wound dressing and method of use
US20130180966A1 (en) 2010-05-04 2013-07-18 Jeffrey M. Gross Laser cutting system and methods for creating self-retaining sutures
US8945156B2 (en) 2010-05-19 2015-02-03 University Of Utah Research Foundation Tissue fixation
US8858577B2 (en) 2010-05-19 2014-10-14 University Of Utah Research Foundation Tissue stabilization system
MX345479B (es) 2010-06-01 2017-02-01 Baxter Int Inc * Proceso para elaborar composiciones hemostaticas secas y estables.
CN103068323B (zh) 2010-06-11 2015-07-22 伊西康有限责任公司 用于内窥镜式和机器人辅助式外科手术的缝合线递送工具
US9232805B2 (en) 2010-06-29 2016-01-12 Biocure, Inc. In-situ forming hydrogel wound dressings containing antimicrobial agents
GB201011173D0 (en) 2010-07-02 2010-08-18 Smith & Nephew Provision of wound filler
US8961501B2 (en) 2010-09-17 2015-02-24 Incept, Llc Method for applying flowable hydrogels to a cornea
KR20130140762A (ko) 2010-11-03 2013-12-24 에티컨, 엘엘씨 약물-용출 자가-유지형 봉합재 및 그 관련 방법
BR112013011582B1 (pt) 2010-11-09 2020-10-20 Ethicon Llc sistema de autorretenção multidirecional removível
GB201020005D0 (en) 2010-11-25 2011-01-12 Smith & Nephew Composition 1-1
WO2012069794A1 (fr) 2010-11-25 2012-05-31 Smith & Nephew Plc Composition i-ii et ses produits et applications
US8852214B2 (en) 2011-02-04 2014-10-07 University Of Utah Research Foundation System for tissue fixation to bone
EP2688490B1 (fr) 2011-03-23 2017-02-01 Ethicon, LLC Sutures à boucle variable autostatique
CN103764217B (zh) 2011-05-26 2017-03-15 雅培心血管系统有限公司 导管的贯通顶端
US20130172931A1 (en) 2011-06-06 2013-07-04 Jeffrey M. Gross Methods and devices for soft palate tissue elevation procedures
US8998059B2 (en) 2011-08-01 2015-04-07 Ethicon Endo-Surgery, Inc. Adjunct therapy device having driver with cavity for hemostatic agent
US9492170B2 (en) 2011-08-10 2016-11-15 Ethicon Endo-Surgery, Inc. Device for applying adjunct in endoscopic procedure
US8998060B2 (en) 2011-09-13 2015-04-07 Ethicon Endo-Surgery, Inc. Resistive heated surgical staple cartridge with phase change sealant
US9101359B2 (en) 2011-09-13 2015-08-11 Ethicon Endo-Surgery, Inc. Surgical staple cartridge with self-dispensing staple buttress
US9999408B2 (en) 2011-09-14 2018-06-19 Ethicon Endo-Surgery, Inc. Surgical instrument with fluid fillable buttress
US9254180B2 (en) 2011-09-15 2016-02-09 Ethicon Endo-Surgery, Inc. Surgical instrument with staple reinforcement clip
US8814025B2 (en) 2011-09-15 2014-08-26 Ethicon Endo-Surgery, Inc. Fibrin pad matrix with suspended heat activated beads of adhesive
US9125649B2 (en) 2011-09-15 2015-09-08 Ethicon Endo-Surgery, Inc. Surgical instrument with filled staple
US10226417B2 (en) 2011-09-16 2019-03-12 Peter Jarrett Drug delivery systems and applications
US9198644B2 (en) 2011-09-22 2015-12-01 Ethicon Endo-Surgery, Inc. Anvil cartridge for surgical fastening device
US9393018B2 (en) 2011-09-22 2016-07-19 Ethicon Endo-Surgery, Inc. Surgical staple assembly with hemostatic feature
US8985429B2 (en) 2011-09-23 2015-03-24 Ethicon Endo-Surgery, Inc. Surgical stapling device with adjunct material application feature
US8899464B2 (en) 2011-10-03 2014-12-02 Ethicon Endo-Surgery, Inc. Attachment of surgical staple buttress to cartridge
US9089326B2 (en) 2011-10-07 2015-07-28 Ethicon Endo-Surgery, Inc. Dual staple cartridge for surgical stapler
CA2851338C (fr) 2011-10-11 2019-11-05 Baxter International Inc. Compositions hemostatiques
EP4137165A1 (fr) 2011-10-11 2023-02-22 Baxter International Inc. Compositions hémostatiques
EP2766060B1 (fr) * 2011-10-11 2022-11-23 Baxter International Inc. Composition hémostatique
CN103889447B (zh) 2011-10-27 2015-11-25 巴克斯特国际公司 止血组合物
US20150159066A1 (en) 2011-11-25 2015-06-11 Smith & Nephew Plc Composition, apparatus, kit and method and uses thereof
WO2013131520A2 (fr) 2012-03-06 2013-09-12 Ferrosan Medical Devices A/S Récipient mis sous pression contenant de la pâte hémostatique
US9439334B2 (en) 2012-04-03 2016-09-06 X-Card Holdings, Llc Information carrying card comprising crosslinked polymer composition, and method of making the same
US9122968B2 (en) 2012-04-03 2015-09-01 X-Card Holdings, Llc Information carrying card comprising a cross-linked polymer composition, and method of making the same
AU2013275758B2 (en) 2012-06-12 2015-03-12 Ferrosan Medical Devices A/S Dry haemostatic composition
US8684963B2 (en) 2012-07-05 2014-04-01 Abbott Cardiovascular Systems Inc. Catheter with a dual lumen monolithic shaft
US9427309B2 (en) 2012-07-30 2016-08-30 Conextions, Inc. Soft tissue repair devices, systems, and methods
US10219804B2 (en) 2012-07-30 2019-03-05 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
US11253252B2 (en) 2012-07-30 2022-02-22 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
US11944531B2 (en) 2012-07-30 2024-04-02 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
US10390935B2 (en) 2012-07-30 2019-08-27 Conextions, Inc. Soft tissue to bone repair devices, systems, and methods
US11957334B2 (en) 2012-07-30 2024-04-16 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
US10835241B2 (en) 2012-07-30 2020-11-17 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
WO2014062839A1 (fr) 2012-10-16 2014-04-24 Surmodics, Inc. Dispositif de pansement et procédés
US9040093B2 (en) 2013-03-13 2015-05-26 Orthovita, Inc. Bone graft materials containing calcium phosphate and chitosan
US9364199B2 (en) 2013-03-14 2016-06-14 Covidien Lp Medical devices
US10906287B2 (en) 2013-03-15 2021-02-02 X-Card Holdings, Llc Methods of making a core layer for an information carrying card, and resulting products
US20160120706A1 (en) 2013-03-15 2016-05-05 Smith & Nephew Plc Wound dressing sealant and use thereof
EP2968647B1 (fr) 2013-03-15 2022-06-29 Smith & Nephew plc Scellement de pansement et son utilisation
JP6446031B2 (ja) * 2013-04-22 2018-12-26 シーランチウム・メディカル・リミテッド フィブリノーゲンをベースとする組織接着性パッチ剤
US11071805B2 (en) 2013-04-22 2021-07-27 Sealantium Medical Ltd. Fibrinogen-based tissue adhesive patches
CA2912357C (fr) 2013-06-21 2019-12-31 Ferrosan Medical Devices A/S Composition seche dilatee sous vide, et seringue pour la retenir
EP2821436A1 (fr) * 2013-07-01 2015-01-07 Allnex Belgium, S.A. Composition composite transparente
JP6489485B2 (ja) 2013-12-11 2019-03-27 フェロサン メディカル デバイシーズ エイ／エス 押し出し増強因子を含んでいる乾燥組成物
JP6325821B2 (ja) * 2014-01-08 2018-05-16 株式会社日本触媒 硫黄原子含有多分岐ポリアルキレングリコール系ブロック共重合体
US11583384B2 (en) 2014-03-12 2023-02-21 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
WO2015138760A1 (fr) 2014-03-12 2015-09-17 Conextions, Inc. Dispositifs, systèmes et méthodes de réparation des tissus mous
KR102264607B1 (ko) 2014-07-17 2021-06-14 더 리전트 오브 더 유니버시티 오브 캘리포니아 생물의학적 적용을 위한 제어가능한 자기-어닐링 마이크로겔 입자
US10201457B2 (en) 2014-08-01 2019-02-12 Surmodics, Inc. Wound packing device with nanotextured surface
KR101982554B1 (ko) * 2014-09-30 2019-05-27 후지필름 가부시키가이샤 싸이올 화합물, 싸이올 화합물의 제조 방법, 폴리머, 조성물, 경화성 조성물, 착색 조성물, 경화막 및 컬러 필터
CA2960309A1 (fr) 2014-10-13 2016-04-21 Ferrosan Medical Devices A/S Composition seche destinee a etre utilisee en hemostase et cicatrisation de plaie
US10653837B2 (en) 2014-12-24 2020-05-19 Ferrosan Medical Devices A/S Syringe for retaining and mixing first and second substances
CN104610512A (zh) * 2015-01-19 2015-05-13 东华大学 一种超柔软互穿网络涂料印花粘合剂的制备方法
WO2017005590A1 (fr) 2015-07-03 2017-01-12 Ferrosan Medical Devices A/S Seringue pour mélanger deux composants et pour conserver un vide dans une condition de stockage
US11931480B2 (en) 2016-02-16 2024-03-19 The Regents Of The University Of California Microporous annealed particle gels and methods of use
JP6764467B2 (ja) * 2016-03-17 2020-09-30 富士フイルム株式会社 多官能チオール化合物の製造方法、多官能チオール化合物、硬化性組成物および硬化性組成物の製造方法
WO2018039331A1 (fr) * 2016-08-23 2018-03-01 The Regents Of The University Of Colorado, A Body Corporate Polymères réticulés et procédés de préparation et d'utilisation de ceux-ci
US11696822B2 (en) 2016-09-28 2023-07-11 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
CN117582559A (zh) 2016-12-29 2024-02-23 泰普治疗公司 用于治疗医疗植入物部位的方法和系统
CA3053647A1 (fr) * 2017-03-09 2018-09-13 Baxter International Inc. Systeme et procedes de depot avec un solvant
US12102317B2 (en) 2017-12-20 2024-10-01 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
US10973509B2 (en) 2017-12-20 2021-04-13 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
US11547397B2 (en) 2017-12-20 2023-01-10 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
EP3762871B1 (fr) 2018-03-07 2024-08-07 X-Card Holdings, LLC Carte métallique
CN112368028A (zh) 2018-05-09 2021-02-12 弗罗桑医疗设备公司 用于制备止血组合物的方法
WO2020172154A1 (fr) 2019-02-18 2020-08-27 The Regents Of The University Of Colorado, A Body Corporate Polymères de réseau et leurs procédés de fabrication et d'utilisation
US20220273842A1 (en) * 2019-07-22 2022-09-01 Nurami Medical Ltd. A tissue-adhesive matrix and uses thereof
US20210213157A1 (en) * 2020-01-09 2021-07-15 Ethicon, Inc. Flexible Gelatin Sealant Dressing with Reactive Components
US11739166B2 (en) 2020-07-02 2023-08-29 Davol Inc. Reactive polysaccharide-based hemostatic agent
US12161777B2 (en) 2020-07-02 2024-12-10 Davol Inc. Flowable hemostatic suspension
WO2022146917A1 (fr) 2020-12-28 2022-07-07 Davol Inc. Matériaux hémostatiques pulvérulents secs réactifs comprenant une protéine et un agent de réticulation à base de polyéthylène glycol modifié multifonctionnalisé
US12220897B2 (en) 2022-10-20 2025-02-11 X-Card Holdings, Llc Core layer for information carrying card, resulting information carrying card, and methods of making the same

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4695602A (en) * 1985-02-28 1987-09-22 Lnp Corporation Fiber reinforced thermoplastics containing silicone interpenetrating polymer networks
WO1997022371A1 (fr) * 1995-12-18 1997-06-26 Collagen Corporation Composition a base de polymeres reticules et leur procede d'utilisation
US5643575A (en) * 1993-10-27 1997-07-01 Enzon, Inc. Non-antigenic branched polymer conjugates
US5681904A (en) * 1996-04-01 1997-10-28 Minnesota Mining And Manufacturing Company Azido polymers having improved burn rate

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4164559A (en) 1977-09-21 1979-08-14 Cornell Research Foundation, Inc. Collagen drug delivery device
US5162430A (en) 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates
US5583114A (en) 1994-07-27 1996-12-10 Minnesota Mining And Manufacturing Company Adhesive sealant composition
WO1997028192A1 (fr) * 1996-01-29 1997-08-07 Charles Doillon Collagene et produits derives exempts de prions, et implants pour applications biomedicales multiples; leurs procedes de fabrication
US6162241A (en) 1997-08-06 2000-12-19 Focal, Inc. Hemostatic tissue sealants
JP3167662B2 (ja) 1997-09-26 2001-05-21 株式会社ウェルパインコミュニケーションズ 電源システム

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4695602A (en) * 1985-02-28 1987-09-22 Lnp Corporation Fiber reinforced thermoplastics containing silicone interpenetrating polymer networks
US5643575A (en) * 1993-10-27 1997-07-01 Enzon, Inc. Non-antigenic branched polymer conjugates
WO1997022371A1 (fr) * 1995-12-18 1997-06-26 Collagen Corporation Composition a base de polymeres reticules et leur procede d'utilisation
US5681904A (en) * 1996-04-01 1997-10-28 Minnesota Mining And Manufacturing Company Azido polymers having improved burn rate

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