EP1874271A4 - MODIFIED RELEASE COMPOSITIONS CONTAINING FLUOROCYTIDINE DERIVATIVE FOR THE TREATMENT OF CANCER - Google Patents

MODIFIED RELEASE COMPOSITIONS CONTAINING FLUOROCYTIDINE DERIVATIVE FOR THE TREATMENT OF CANCER

Info

Publication number: EP1874271A4
Authority: EP; European Patent Office
Prior art keywords: cancer; treatment; compositions containing; modified release; release compositions
Prior art date: 2005-04-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP06749864A

Other languages

German (de)

French (fr)

Other versions

EP1874271A1 (en

Inventor

Scott Jenkins

Gary Liversidge

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Perrigo Pharma International DAC

Original Assignee

Elan Pharma International Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-04-12

Filing date

2006-04-12

Publication date

2012-01-25

2006-04-12 Application filed by Elan Pharma International Ltd filed Critical Elan Pharma International Ltd

2008-01-09 Publication of EP1874271A1 publication Critical patent/EP1874271A1/en

2012-01-25 Publication of EP1874271A4 publication Critical patent/EP1874271A4/en

Status Withdrawn legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

EP06749864A 2005-04-12 2006-04-12 MODIFIED RELEASE COMPOSITIONS CONTAINING FLUOROCYTIDINE DERIVATIVE FOR THE TREATMENT OF CANCER Withdrawn EP1874271A4 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US67050705P	2005-04-12	2005-04-12
PCT/US2006/013629 WO2006110800A1 (en)	2005-04-12	2006-04-12	Modified release compositions comprising a fluorocytidine derivative for the treatment of cancer

Publications (2)

Publication Number	Publication Date
EP1874271A1 EP1874271A1 (en)	2008-01-09
EP1874271A4 true EP1874271A4 (en)	2012-01-25

Family

ID=37087358

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP06749864A Withdrawn EP1874271A4 (en)	2005-04-12	2006-04-12	MODIFIED RELEASE COMPOSITIONS CONTAINING FLUOROCYTIDINE DERIVATIVE FOR THE TREATMENT OF CANCER

Country Status (7)

Country	Link
EP (1)	EP1874271A4 (en)
JP (1)	JP2008535920A (en)
CA (1)	CA2604192A1 (en)
DE (1)	DE112006000873T5 (en)
ES (1)	ES2327195B1 (en)
GB (1)	GB2442615A (en)
WO (1)	WO2006110800A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20080085310A1 (en) *	2006-10-06	2008-04-10	Maria Oksana Bachynsky	Capecitabine rapidly disintegrating tablets
US20110027374A1 (en) *	2008-12-16	2011-02-03	Maria Oksana Bachynsky	Capecitabine rapidly disintegrating tablets
RU2017144564A (en) *	2015-06-13	2019-07-16	Интас Фармасьютикалс Лтд.	Sustained-release capecitabine capsules
AU2018214291A1 (en) *	2017-02-06	2019-08-01	Intas Pharmaceuticals Ltd.	Composition comprising immediate release and extended release Capecitabine

Citations (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2000025752A1 (en) *	1998-11-02	2000-05-11	Church, Marla, J.	Multiparticulate modified release composition
US6110498A (en) *	1996-10-25	2000-08-29	Shire Laboratories, Inc.	Osmotic drug delivery system
WO2001037808A1 (en) *	1999-11-23	2001-05-31	Lipocine, Inc.	Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US20010038858A1 (en) *	1994-08-04	2001-11-08	Roser Bruce J.	Solid delivery systems for controlled release of molecules incorporated therein and methods of making same
US20020019365A1 (en) *	2000-06-02	2002-02-14	Jones Richard E.	Pharmaceutical compositions of 2'-deoxy-2'-(fluoromethylene)cytidine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6005098A (en) *	1998-02-06	1999-12-21	Hoffmann-La Roche Inc.	5'deoxycytidine derivatives
SK12242002A3 (en) *	2000-02-28	2003-02-04	Aventis Pharma S. A.	A composition comprising camptothecin and a pyrimidine derivative for the treatment of cancer

2006
- 2006-04-12 JP JP2008506628A patent/JP2008535920A/en active Pending
- 2006-04-12 CA CA002604192A patent/CA2604192A1/en not_active Abandoned
- 2006-04-12 GB GB0720886A patent/GB2442615A/en active Pending
- 2006-04-12 DE DE112006000873T patent/DE112006000873T5/en not_active Withdrawn
- 2006-04-12 EP EP06749864A patent/EP1874271A4/en not_active Withdrawn
- 2006-04-12 WO PCT/US2006/013629 patent/WO2006110800A1/en not_active Ceased
- 2006-04-12 ES ES200750061A patent/ES2327195B1/en not_active Withdrawn - After Issue

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20010038858A1 (en) *	1994-08-04	2001-11-08	Roser Bruce J.	Solid delivery systems for controlled release of molecules incorporated therein and methods of making same
US6110498A (en) *	1996-10-25	2000-08-29	Shire Laboratories, Inc.	Osmotic drug delivery system
WO2000025752A1 (en) *	1998-11-02	2000-05-11	Church, Marla, J.	Multiparticulate modified release composition
WO2001037808A1 (en) *	1999-11-23	2001-05-31	Lipocine, Inc.	Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US20020019365A1 (en) *	2000-06-02	2002-02-14	Jones Richard E.	Pharmaceutical compositions of 2'-deoxy-2'-(fluoromethylene)cytidine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2006110800A1 *

Also Published As

Publication number	Publication date
JP2008535920A (en)	2008-09-04
GB2442615A (en)	2008-04-09
WO2006110800A1 (en)	2006-10-19
EP1874271A1 (en)	2008-01-09
DE112006000873T5 (en)	2008-03-06
ES2327195B1 (en)	2010-07-09
ES2327195A1 (en)	2009-10-26
GB0720886D0 (en)	2007-12-05
CA2604192A1 (en)	2006-10-19

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Legal Events

Date	Code	Title	Description
2007-12-07	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2008-01-09	17P	Request for examination filed	Effective date: 20071108
2008-01-09	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): FR IE IT
2008-06-04	DAX	Request for extension of the european patent (deleted)
2008-06-04	RBV	Designated contracting states (corrected)	Designated state(s): FR IE IT
2012-01-25	A4	Supplementary search report drawn up and despatched	Effective date: 20111229
2012-01-25	RIC1	Information provided on ipc code assigned before grant	Ipc: A61K 9/14 20060101AFI20111222BHEP Ipc: A61K 31/7068 20060101ALI20111222BHEP Ipc: A61K 9/48 20060101ALI20111222BHEP Ipc: A61K 9/20 20060101ALI20111222BHEP Ipc: A61K 9/28 20060101ALI20111222BHEP Ipc: A61K 9/16 20060101ALI20111222BHEP
2012-12-21	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2013-01-23	18D	Application deemed to be withdrawn	Effective date: 20120728