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EP1872765A1 - Emballage du type blister et procédé d'emballage automatisé d'une composition determinée individuelle - Google Patents

Emballage du type blister et procédé d'emballage automatisé d'une composition determinée individuelle Download PDF

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Publication number
EP1872765A1
EP1872765A1 EP06116277A EP06116277A EP1872765A1 EP 1872765 A1 EP1872765 A1 EP 1872765A1 EP 06116277 A EP06116277 A EP 06116277A EP 06116277 A EP06116277 A EP 06116277A EP 1872765 A1 EP1872765 A1 EP 1872765A1
Authority
EP
European Patent Office
Prior art keywords
blister pack
application
personalized
pack according
person
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP06116277A
Other languages
German (de)
English (en)
Other versions
EP1872765B1 (fr
Inventor
Edwin Kohl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to PL06116277T priority Critical patent/PL1872765T3/pl
Application filed by Individual filed Critical Individual
Priority to AT06116277T priority patent/ATE429893T1/de
Priority to DE200650003608 priority patent/DE502006003608D1/de
Priority to ES06116277T priority patent/ES2326333T3/es
Priority to EP20060116277 priority patent/EP1872765B1/fr
Priority to DK06116277T priority patent/DK1872765T3/da
Priority to ES07786876T priority patent/ES2440486T3/es
Priority to JP2009517203A priority patent/JP2009540989A/ja
Priority to US12/306,781 priority patent/US20090277815A1/en
Priority to EP20070786876 priority patent/EP2032113B1/fr
Priority to PCT/EP2007/056469 priority patent/WO2008000790A1/fr
Publication of EP1872765A1 publication Critical patent/EP1872765A1/fr
Priority to HK08103565.1A priority patent/HK1109329B/xx
Application granted granted Critical
Publication of EP1872765B1 publication Critical patent/EP1872765B1/fr
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • A61J1/035Blister-type containers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A61J7/0409Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
    • A61J7/0481Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers working on a schedule basis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A61J7/0409Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
    • A61J7/0418Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with electronic history memory
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A61J7/0409Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
    • A61J7/0454Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers for dispensing of multiple drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A61J7/0409Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
    • A61J7/0463Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers for multiple patients

Definitions

  • the invention relates to a blister pack for the automated packaging of an individually defined product combination, in particular consisting of medicaments for a specific person and for a fixed period of time, for example a week, and an associated packaging method.
  • a blister pack for the weekly drug needs of a patient known to take the medication in a order by date, day of the week and time of day (morning, noon and evening and / or night) order.
  • the receiving compartments of the blister pack for receiving the respective medicaments are arranged in matrix form with seven daily lines, each with at least three time of day compartments, which are covered in total by a continuous blister foil.
  • Affixed to the blister pack is a carton-shaped lid, on which the patient-individual the composition of the individual time-of-day subjects as well as prescribing information concerning the respective medicaments is contained.
  • Such packaging units are for patients who need to take several different medications regularly, a help not only to remember the intake of important drugs and on the other hand to keep a reliable overview of what medications are already taken to u. U. to avoid harmful over-medication.
  • the printed instructions for taking in the described weekly blister pack may be difficult to read due to the large number of necessary information, especially for older patients due to the limited font for reasons of space font. In addition, there is a risk that the patient misses the time for the application of a drug.
  • a personalized blister pack for the automated packaging of an individually defined product combination, in particular medicines, a particular person for a fixed period comprising several, each closed by a film storage compartments for the products of the product combination, which receptacles each a specific application time within the assigned to a predetermined period of time, and a memory device, are stored on the application data of the products of the product composition of the particular person for the specified period of time.
  • the storage device makes it possible to individually store the application data such as the product itself, the dose, application times, etc., for the respective person, so that the data can be made accessible by audible or visual output.
  • the memory device enables the Issue an application reminder to remind the patient to take certain medications or other supplements at a specific time.
  • the reminder signal may be an acoustic or an optical or even a vibration alarm signal. Signal parameters such as the volume of an acoustic signal may be adjustable, for example.
  • an acknowledgment function can be provided, either by the patient actively confirming the product application by pressing a button or the like, or by providing a sensor for each receptacle of the blister pack that detects a tearing of the film of the corresponding compartment.
  • the memory element may, for example, be an EPROM memory element or else an RFID or a flash memory element.
  • the memory element may be formed as write-once memory for single use of the memory element or as rewritable memory for multiple use of the memory device.
  • the storage device may preferably include an interface for receiving updated application data for the patient, for example via a mobile radio network, wireless LAN, Bluetooth or the like.
  • the personal identification data associated with the particular person may be stored in the memory device, wherein the latter may have an output device for outputting the personal identification data.
  • the blister pack may further be provided with an identifier assigned to the particular person, for example as a barcode or the like.
  • the storage means is removably attached to the blister pack and includes a support means such as a fastening tape or the like on.
  • the storage device preferably has a waterproof, washable and shockproof housing.
  • the blister pack according to the invention is suitable for packaging a wide variety of products such as medicines, vitamin preparations, nutritional supplements and the like, wherein the storage device can store the application data for the products contained in the blister pack, but also other products.
  • a further object of the present invention is to propose a method for automatically packaging a product combination determined in each case individually, in particular consisting of medicaments, for a large number of persons for a certain period of time (eg one week) and simultaneously for a need-based one Reliable support for the application of the delivered products.
  • the object is achieved by a method comprising the steps of recording individual product application data of each of the plurality of persons and storing in a database, reading out the application data associated with a person for the specified period of time from the database and based on the read application data, provisioning and automated Packaging of the respective product composition in a person-individual packaging unit, storage of the read application data on a person-specific storage device, which storage device comprises an application reminder function based on the stored application data, and attaching the storage devices to the respective person-individual packaging units.
  • the person or the patient is provided with the application data of the products contained in the packaging unit and, if appropriate, further products to be used in order to support a demand-oriented application on the storage device.
  • the reminder function reminds the patient of a timely medication.
  • the reminder can be done by acoustic signal, optical signal or the like.
  • the storage device can be removably attached to the packaging unit (in particular blister pack), and be designed either for single or multiple use. With repeated use, the application data can be updated wirelessly, for example via the mobile network, wireless LAN or a Bluetooth interface.
  • FIG. 1 shows a schematic perspective view of an exemplary embodiment of a weekly blister according to the invention with a storage unit.
  • FIG. 2 is a block diagram of an embodiment of the memory unit according to the invention.
  • FIG. 3 is a schematic illustration for explaining an embodiment of the method according to the invention.
  • FIG. 4 is a flowchart for explaining the method steps of the method according to the invention.
  • FIG. 1 shows an exemplary embodiment of a personalized blister pack 20 according to the invention.
  • This is designed as a so-called weekly blister for supplying a person or a patient with medicaments and similar products such as vitamin supplements, nutritional supplements etc. for a period of one week.
  • the invention is not limited to a specific period of time.
  • a detachable by a perforation line of 24 in the example shown four receiving compartments 22 are provided, each of the applied products for "early”, “noon”, “evening” or “at night” or for breakfast, lunch, dinner and bedtime.
  • a different number of storage compartments 22 may be provided, for example, three storage compartments for each meal before, during or after the particular meal.
  • the - in the embodiment shown in Figure 1 - a total of 28 receiving compartments 22 are made of a preferably transparent thermoplastic material inexpensively mass-produced by deep drawing and have enough space for each of a plurality of tablets, capsules, dragees, etc. All receiving compartments 22 may by a common Foil 25, for example.
  • a thin aluminum foil be closed and be provided with symbols for the withdrawal time (morning, noon, evening, night). By tearing the thin foil, the patient can comfortably remove the products to be taken at the time of day.
  • the personalized blister pack 20 may be provided with an identifier 29 associated with the respective patient, for example as a barcode is trained. Other types of personal identifiers are also possible.
  • the blister pack as in the WO 2005/102862 have described a (not shown in Figure 1) hinged lid.
  • the blister pack 20 is further provided as shown in Figure 1 with a memory device 50 in which the application data of the storage compartments and possibly other products such as dietary supplements, ointments, etc. are stored.
  • the storage device 50 can be designed as a single-use memory for single use for the period of use of the blister pack (for example, a week) or as multiple times writable memory that is returned to the pharmacy after the week for further use or by remote data transmission for will be updated next week.
  • the storage device 50 may be removably attached to the blister pack 20 with adhesives, hook-and-loop fastener, fastener tape, or the like so that the patient can easily detach them from the blister pack without damaging the blister sheet 25.
  • the storage device may have a carrying device such as the illustrated fastening strap 60, so that the patient can, for example, hang the storage device around his neck or otherwise carry him with him.
  • the memory device has a memory element 52, which as mentioned may be a write once or a rewritable memory.
  • a memory element 52 which as mentioned may be a write once or a rewritable memory.
  • EPROM or flash memory device may be used, and other memory technologies - such as those known from smart cards - may also be used.
  • the memory device 50 has an interface unit 54, which allows a description of the memory with the product application data.
  • the interface 54 may also be designed to update the data stored in the memory element 52, for example by infrared, Bluetooth, wireless LAN or a mobile network.
  • the memory device 50 comprises a timer 56 and an output unit 58 in order to realize a reminder function for the patient.
  • the timer 56 supplies Signal to the Ausgeabe worn 58, which then emits a warning signal.
  • the output device 58 is a miniaturized loudspeaker that emits a beep, or better, a synthesized speech signal with specific application notes, such as "take a red tablet before lunch,” or "take heart remedies for dinner.”
  • the volume can be adjustable by means of a (not shown) control device.
  • an optical output device may be used, which outputs the application notes on a small display.
  • the most comfortable reminder function for the patient should be possible with the help of speech synthesis.
  • personal identification data associated with the respective patient are stored in addition to the application data.
  • the output device 58 can output these for the user / patient for checking.
  • the memory device 50 may be designed to be inexpensive and space and weight-saving, such as a SIM card of a mobile phone.
  • a power supply unit (not shown in FIG. 2), such as a small battery or a capacitor, may be provided.
  • the Memory element 50 can also be designed as a passive element in accordance with an RFID chip and receive radio frequency signals via the interface unit 54 provided with a radio frequency antenna and also use these for power supply.
  • the storage device is provided with a waterproof, washable and impact-resistant, yet inexpensive housing, for example. Made of plastic.
  • the reminder signal possibly disturbing
  • a key or the like for a certain period of time, such as 10 minutes.
  • Such functionality is known, for example, with alarm clocks.
  • the suppressed signal can then be output later with a time delay to later remind the patient of the (possibly missed) product application.
  • a sensor device can be provided for this purpose, which detects a tearing of the corresponding film section for each of the receiving compartments 22 and thus closes the prescription-related medication application.
  • the individual prescription data ie the medicaments and other products prescribed to the patient (vitamin preparations, Dietary supplements, ointments, etc.) is preferably detected in the respective patient care pharmacy and stored in the subsequent step S2 in a database 80.
  • the database 80 as outlined in FIG. 3, it may be a decentralized, maintained in the pharmacy or even a central database.
  • a packaging machine or equipping machine 90 equipped to supply a large number (possibly several hundreds of thousands) of patients is supplied with medicines in large quantities by manufacturers.
  • the application data of patients from the database 80 and each patient in the subsequent process step S4 an individual blister pack 20th in which the medicines prescribed for that patient for the period are packaged.
  • step S5 Based on the read application data, in a further method step S5, these application data are also stored on a memory device 50 assigned to the respective patient, and the memory device is then attached to the packaging unit 20 in step S6.
  • the method steps S5 and S6 can also be performed in reverse order of time.
  • step S7 the correspondence of the personal identification data stored in the storage device with the identifier 29 attached to the packaging unit is checked.
  • a verification of the correctness of the assignment of packaging unit 20 with the stored in the memory device 50 application data can be done so that the patient in any case its associated products and application data are delivered.
  • the blister packs (eg weekly blister) produced in such a fast, safe and reasonably priced manner are delivered to the respective pharmacies, which then provide the weekly blisters provided with the storage element to the respective patient.
  • the storage device 50 can also contain application data of products that are not delivered with the blister, for example, ointments, medicinal teas, bath treatments or the like.
  • the application data on the storage device is preferably updated wirelessly, for example by means of a special mobile radio signal or also a Bluetooth or infrared interface provided in the pharmacy.
  • the invention thus enables the fast, safe and inexpensive supply of a large number of patients with the individually prescribed product or drug composition.
  • the convenient handling of the blister pack and the memory device provided with a reminder function supports a need-based medication of the patient, so that he is more able to provide himself and is not dependent on inpatient care.

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medical Informatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Containers And Plastic Fillers For Packaging (AREA)
  • Basic Packing Technique (AREA)
  • Auxiliary Devices For And Details Of Packaging Control (AREA)
  • Packages (AREA)
EP20060116277 2006-06-29 2006-06-29 Emballage du type blister et procédé d'emballage automatisé d'une composition determinée individuelle Not-in-force EP1872765B1 (fr)

Priority Applications (12)

Application Number Priority Date Filing Date Title
AT06116277T ATE429893T1 (de) 2006-06-29 2006-06-29 Personalisierte blisterpackung und verfahren zur automatischen verpackung einer individuell festgelegten produktzusammenstellung
DE200650003608 DE502006003608D1 (de) 2006-06-29 2006-06-29 Personalisierte Blisterpackung und Verfahren zur automatischen Verpackung einer individuell festgelegten Produktzusammenstellung
ES06116277T ES2326333T3 (es) 2006-06-29 2006-06-29 Envase blister personalizado y procedimiento de envasado automatico de una combinacion de productos individualmente establecida.
EP20060116277 EP1872765B1 (fr) 2006-06-29 2006-06-29 Emballage du type blister et procédé d'emballage automatisé d'une composition determinée individuelle
DK06116277T DK1872765T3 (da) 2006-06-29 2006-06-29 Personliggjort blisterpakning og fremgangsmåde til automatisk pakning af en individuelt bestemt produkkombination
PL06116277T PL1872765T3 (pl) 2006-06-29 2006-06-29 Spersonalizowane opakowanie typu blister i sposób automatycznego opakowywania indywidualnie ustalonej kompozycji produktu
ES07786876T ES2440486T3 (es) 2006-06-29 2007-06-28 Envase blíster personalizado
JP2009517203A JP2009540989A (ja) 2006-06-29 2007-06-28 個人用ブリスタパック
US12/306,781 US20090277815A1 (en) 2006-06-29 2007-06-28 Personalized blister pack
EP20070786876 EP2032113B1 (fr) 2006-06-29 2007-06-28 Emballage du type blister
PCT/EP2007/056469 WO2008000790A1 (fr) 2006-06-29 2007-06-28 Plaquette thermoformée personnalisée
HK08103565.1A HK1109329B (en) 2008-03-31 Personalized blister pack and method for automated packaging of an individually determined composition

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP20060116277 EP1872765B1 (fr) 2006-06-29 2006-06-29 Emballage du type blister et procédé d'emballage automatisé d'une composition determinée individuelle

Publications (2)

Publication Number Publication Date
EP1872765A1 true EP1872765A1 (fr) 2008-01-02
EP1872765B1 EP1872765B1 (fr) 2009-04-29

Family

ID=37309378

Family Applications (2)

Application Number Title Priority Date Filing Date
EP20060116277 Not-in-force EP1872765B1 (fr) 2006-06-29 2006-06-29 Emballage du type blister et procédé d'emballage automatisé d'une composition determinée individuelle
EP20070786876 Not-in-force EP2032113B1 (fr) 2006-06-29 2007-06-28 Emballage du type blister

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP20070786876 Not-in-force EP2032113B1 (fr) 2006-06-29 2007-06-28 Emballage du type blister

Country Status (9)

Country Link
US (1) US20090277815A1 (fr)
EP (2) EP1872765B1 (fr)
JP (1) JP2009540989A (fr)
AT (1) ATE429893T1 (fr)
DE (1) DE502006003608D1 (fr)
DK (1) DK1872765T3 (fr)
ES (2) ES2326333T3 (fr)
PL (1) PL1872765T3 (fr)
WO (1) WO2008000790A1 (fr)

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US20090277815A1 (en) 2009-11-12
ES2326333T3 (es) 2009-10-07
HK1109329A1 (zh) 2008-06-06
ATE429893T1 (de) 2009-05-15
JP2009540989A (ja) 2009-11-26
DK1872765T3 (da) 2009-08-17
DE502006003608D1 (de) 2009-06-10
EP1872765B1 (fr) 2009-04-29
EP2032113B1 (fr) 2013-10-30
ES2440486T3 (es) 2014-01-29
EP2032113A1 (fr) 2009-03-11
WO2008000790A1 (fr) 2008-01-03
PL1872765T3 (pl) 2009-10-30

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