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EP1768722A1 - Canules et systeme presentant une resistance reduite a l'ecoulement - Google Patents

Canules et systeme presentant une resistance reduite a l'ecoulement

Info

Publication number
EP1768722A1
EP1768722A1 EP05757823A EP05757823A EP1768722A1 EP 1768722 A1 EP1768722 A1 EP 1768722A1 EP 05757823 A EP05757823 A EP 05757823A EP 05757823 A EP05757823 A EP 05757823A EP 1768722 A1 EP1768722 A1 EP 1768722A1
Authority
EP
European Patent Office
Prior art keywords
cannula
lumen
blood
multilumen
distal end
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP05757823A
Other languages
German (de)
English (en)
Inventor
Robert Pecor
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orqis Medical Corp
Original Assignee
Orqis Medical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/865,045 external-priority patent/US20050277804A1/en
Priority claimed from US10/866,535 external-priority patent/US7445592B2/en
Priority claimed from US10/866,649 external-priority patent/US20050277870A1/en
Application filed by Orqis Medical Corp filed Critical Orqis Medical Corp
Publication of EP1768722A1 publication Critical patent/EP1768722A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M25/0026—Multi-lumen catheters with stationary elements
    • A61M25/003—Multi-lumen catheters with stationary elements characterized by features relating to least one lumen located at the distal part of the catheter, e.g. filters, plugs or valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3653—Interfaces between patient blood circulation and extra-corporal blood circuit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3653—Interfaces between patient blood circulation and extra-corporal blood circuit
    • A61M1/3659—Cannulae pertaining to extracorporeal circulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M25/0026—Multi-lumen catheters with stationary elements
    • A61M25/0032—Multi-lumen catheters with stationary elements characterized by at least one unconventionally shaped lumen, e.g. polygons, ellipsoids, wedges or shapes comprising concave and convex parts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A61M25/007—Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0074—Dynamic characteristics of the catheter tip, e.g. openable, closable, expandable or deformable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M27/00—Drainage appliance for wounds or the like, i.e. wound drains, implanted drains
    • A61M27/002—Implant devices for drainage of body fluids from one part of the body to another
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A61M2025/0073—Tip designed for influencing the flow or the flow velocity of the fluid, e.g. inserts for twisted or vortex flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M27/00—Drainage appliance for wounds or the like, i.e. wound drains, implanted drains
    • A61M27/002—Implant devices for drainage of body fluids from one part of the body to another
    • A61M2027/004—Implant devices for drainage of body fluids from one part of the body to another with at least a part of the circuit outside the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3507—Communication with implanted devices, e.g. external control
    • A61M2205/3523—Communication with implanted devices, e.g. external control using telemetric means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3546—Range
    • A61M2205/3561—Range local, e.g. within room or hospital
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A61M25/0071—Multiple separate lumens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0074—Dynamic characteristics of the catheter tip, e.g. openable, closable, expandable or deformable
    • A61M25/0075—Valve means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation

Definitions

  • a cannula system includes a multilumen cannula and a dilator.
  • the multilumen cannula includes a first elongate body and a second elongate body.
  • the first elongate body has a proximal portion, a distal portion, and a first lumen that extends through the first elongate body.
  • the first lumen is configured to reduce resistance to flow therethrough.
  • a percutaneous cannula comprises a main cannula portion, a discharge opening, and a transition portion.
  • the transition portion extends distally from the main cannula portion and has a lumen therethrough.
  • the transition portion is configured to engage an adjacent wall of a blood vessel to space the discharge opening of the cannula from the adjacent wall of the blood vessel. Blood discharge from a blood flow lumen through the discharge opening that directly impacts upon the blood vessel wall is substantially reduced by this arrangement.
  • a percutaneous cannula comprises a main cannula portion and a transition portion.
  • the transition portion has a helical shape and includes a plurality of axially spaced discharge apertures.
  • one or more of the conduits could be connected to veins, i the arrangement of Figure 3, the inflow conduit 150 A is connected to the left femoral artery 26 while the inflow conduit 150B is connected to the left femoral vein 30.
  • the outflow conduit 152A is connected to the left subclavian artery 24 while the outflow conduit 152B is connected to the left carotid artery 22.
  • at least one of the conduits 150A, 150B, 152A, and 152B is coupled with a corresponding vessel via a cannula.
  • the inflow conduit 150B is coupled with the left femoral vein 30 via a cannula 160.
  • the outflow port 492 may be situated within, for example, a mesenteric artery 494 such that blood flow results from the left femoral artery 26 to the mesenteric artery 494.
  • the blood could discharge, for example, directly into the descending aorta proximate an arterial branch, such as the renal arteries, the left subclavian artery, or directly into the peripheral mesenteric artery 494, as illustrated in Figure 11.
  • the multilumen cannula 484 preferably is made of material sufficiently flexible and resilient to permit the patient 12 to comfortably move about while the cannula 484 is indwelling in the patient's blood vessels without causing any vascular trauma.
  • the intrasvascular extracardiac system 642 may further comprise inflow and/or outflow conduits or cannulae (not shown) fluidly connected to the pumping means 644, e.g., to the inlet and outlet of pump 646.
  • Any suitable conduit or cannula can be employed.
  • a cannula having a redirecting tip portion such as the any of the cannulae of Figures 17A - 32B, could be coupled with an intrasvascular extracardiac system.
  • r is the radius of the vessel being assessed
  • ⁇ is the frequency of the patient's heartbeat
  • ⁇ the viscosity of the fluid.
  • a Womersley number of at least 6 is preferred, although a value as low as 5 would be acceptable.
  • the cannula 702 is defined by a proximal end 708, a distal end 710, and a blood-flow lumen 712 extending substantially entirely therethrough.
  • the transition portion 706 may be a discrete component connected in a suitable fashion to the main cannula portion 704.
  • the transition portion 706 is configured to re-direct blood-flow in a manner discussed below.
  • the main cannula portion 704 is generally cylindrical, extending along a longitudinal axis Li from the proximal end 708 toward the transition portion 706.
  • the cannula 702 could be configured to have a plurality of lumens therethrough that can be employed to considerable advantage in connection with heart assist systems adapted for single-site application.
  • the guide-member 724 is a standard guidewire used in percutaneous procedures.
  • the straightener 726 is a stiff member that reduces the profile of the transition portion 706, as discussed above, hi one embodiment, the straightener 726 is a stiff cylindrical rod with a lumen extending therethrough. The lumen in the straightener 726 is sized to receive the guide-member 724. In the illustrated embodiment, the outer diameter of the straightener 726 is sized to be received by the lumen 712 of the percutaneous cannula 702. The straightener 726 is stiffer than the percutaneous cannula 702.
  • the blood flow exiting the lumen 754 is generally away from a wall 764 of the vessel V which is nearest to the transition portion 744.
  • the cannula 740 may be applied so that the blood flow exiting the lumen 754 also is generally in the same direction of the flow of blood in the vessel V.
  • a system 770 for deploying the cannula 740 may be provided.
  • the system 770 is similar to the system 722.
  • the system 770 includes the percutaneous cannula 740, a guide-member 772, and a straightener 774.
  • the cannula 830 is configured to convey blood between two or more vessels. In other embodiments and applications, the cannula 830 is configured to convey blood from one area of a vessel to another area of the vessel. An arrow 838 illustrates the blood- flow within the lumen 836, where the cannula 830 is applied as an outflow cannula. [0193] In one embodiment, the tip portion 834 includes a plurality of apertures 840 to direct blood flow between the lumen 836 and the vessel V in an advantageous manner, e.g., to minimize or eliminate any potentially harmful interactions between the cannula 830 and the vessel V.
  • the cannula 850 can also be applied to convey blood from one portion of a vessel, into the lumen 856, and out of the lumen 856 into another part of a vessel. As with the other cannulae described herein, the cannula 850 can be configured as either a single or as a multilumen cannula. [0196]
  • the tip portion 854 includes a curved surface 862 positioned distal of the blood-flow lumen 856.
  • the funnel portion 868 directs substantially all of the blood that is flowing in the lumen 856 toward the surface 862 of the tip portion 854, which redirects the blood-flow as discussed above.
  • the cannula 850 redirects blood-flow to prevent the blood-flow exiting the distal end 860 from immediately discharging against a wall of the vessel. Thus the cannula 850 reduces the likelihood that the blood-flow will have an adverse effect on the vessel in which the cannula 850 resides or on the vasculature in general.
  • the cannula 850 is provided with means for sealing the guide-member lumen 858.
  • the sealing means can be any suitable structure.
  • One embodiment provides a mechanical valve 870.
  • the cannula 902 may be configured as a single or a multiple lumen cannula, as discussed above.
  • the tip portion 906 like the tip portions of the other cannulae described herein, may be made of a similar material or any other suitable material.
  • the tip portion 906 is configured to direct blood-flow in a direction generally opposite of the direction of flow through the lumen 910.
  • the average direction of blood flow out of the tip portion 906 is along a line that forms about a one-hundred sixty-five degree angle with respect to the longitudinal axis (not shown) of the lumen 910.
  • the tip portion 906 has a plurality of lateral openings 912 located near the distal end 908 and a redirecting member 914.
  • the thickness of the redirecting member 914 can be reduced to enable it to expand an equivalent amount as a fully covering member at a lower pressure.
  • the hardness of the redirecting member 914 can be reduced to enable the member 914 to expand an equivalent amount at a lower pressure.
  • the cannula 902 has a binary construction that provides a redirecting member 914 that has two discrete pre-defined configurations. This construction is analogous to that of an umbrella, which may be actuated from a collapsed, low profile configuration to a pre-determined, expanded operational configuration.
  • the redirecting member 914 has a first, pre-defined configuration for delivery, e.g., a collapsed configuration, and a second, pre-defined configuration for operation.
  • the surface 920 and / or the redirecting member 914 direct the blood in a direction generally opposite of the direction of blood-flow in the lumen 910.
  • the cannula 902 may advantageously prevent blood-flow exiting the tip portion 906 from immediately discharging against a wall of the vessel. The likelihood of any deleterious effect on the vessel in which the cannula 902 is applied or other harm to the vasculature due to the operation of the cannula 902 is thereby reduced.
  • the tip portion 906 includes a tapered portion 922.
  • the S-shaped configuration provides a first lateral extending portion 950 and a second laterally extending portion 952.
  • the first laterally extending portion 950 may extend laterally until it engages a wall W 1 of the vessel V.
  • the lateral extent of the first laterally extending portion 950 is preferably sufficient to cause the distal end of the main caimula portion 944 to be moved adjacent to, or even to engage, the opposite wall W 2 of the vessel V.
  • the lateral extent of the second laterally extending portion 952 is preferably sufficient to position the distal end of the transition portion 946 about in the center of the vessel V.
  • the cannula 970 is configured so that it can be inserted into the vasculature at another non-primary artery, e.g., an axillary artery, and advanced until the first distal end 990 is at, adjacent to, or within any of the foregoing arteries (e.g., an iliac or femoral artery) or any other of the vessels or classes of vessels described herein.
  • the cannula 970 is configured so that the length of the first lumen 982 from the proximal end 986 to the first distal end 990 is between about 60 and about 90 cm.
  • the cannula 1666 In order to minimize the flow resistance in the cannula 1666, it is desirable to design the cannula so that the distal portion 1692 comprises as much of the total length of the cannula 1666 as is possible, given other constraints on the cannula 1666. Thus, the length of the proximal portion 1682, and therefore the length of the second lumen 1674, will be minimized as much as is possible.
  • the cross- sectional shape of the lumen 1734 preferably is circular at points within the proximal portion 1746, the transition portion 1748, and the distal portion 1754.
  • the cross-sectional shape of the second lumen 1734 is circular along the entire length of the first elongate portion 1732.
  • the inner cross-sectional size of the first lumen 1734 expands compared to the inner-cross-sectional size of the first lumen 1734 in the proximal portion 1746 of the multilumen cannula 1730 distal a location corresponding to the second distal end 1742.
  • the length of the transition portion 1748 may be any suitable length, e.g., one that provides gradual increase distally to prevent abrupt changes in flow direction of the blood. In one embodiment, the length of the transition portion 1748 is about one- half inch. In one embodiment, the length of the transition portion 1748 is about one inch or less. In another embodiment, the length of the transition portion 1748 is about one inch.
  • a cannula assembly includes a dilator that is insertable through the distally increasing lumen and that can be configured after insertion into the lumen to reduce trauma to surrounding tissue during insertion of the cannula assembly.
  • a dilator that is insertable through the distally increasing lumen and that can be configured after insertion into the lumen to reduce trauma to surrounding tissue during insertion of the cannula assembly.
  • the expandable member 1780 may be inflated with saline solution or any other suitable liquid or gas.
  • the dilator 1778 may also include a valve 1786 as shown in Figure 34 in fluid communication with the inflation lumen.
  • the valve 1786 can take any suitable form. In one embodiment, the valve 1786 can be actuated to a closed position after inflation fluid from the inflation means inflates the expandable member 1780 and can be actuated to an open position to allow the inflation fluid in the expandable member 1780 to escape from the expandable member 1780.
  • This arrangement will facilitate moving the first elongate portion 1762 to the proper position while the cannula 1760 is inserted into a vessel 1792 of the patient and therefore not visible.
  • the second elongate portion 1764 may be translated, rather than the first elongate portion 1762.
  • the cannula 1760 must be inserted into the vessel 1792 so that the entire transition portion 1774 is located within the vessel 1778.
  • care should be taken that the second distal end 1770 is not moved proximal the cannulation site 1794.
  • the pump 1798 may be any suitable pump, e.g., any of those discussed above.
  • the pump 1798 may be one that is configured to pump blood at subcardiac rates.
  • the pump 1798 may also be implanted subcutaneously, e.g., just beneath the skin or within the vasculature, as discussed above.
  • Arrow 1808 indicates blood flow that is conveyed from the pump 1798 to the first proximal end 1768 of the first elongate body 1762 through a conduit 1810 or other suitable conveyance. Blood flow enters the first lumen at the first proximal end 1768 and flows distally therein, as indicated by arrow 1812 to the transition portion 1774.
  • the pump is to be implanted into the patient, or the patient is desired to be ambulatory, it is desirable to minimize both the size and power consumption of the pump.
  • power consumption can be reduced by reducing the flow resistance in these cannulae.
  • the flow resistance of a cannula can be reduced by decreasing the overall length of the cannula, decreasing the viscosity of the fluid, or increasing the cross-sectional size of the cannula lumen or interior, as discussed above.
  • the total cross-sectional size of the cannula is restricted by the size of the blood vessel into which the cannula is inserted.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Physics & Mathematics (AREA)
  • Geometry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • External Artificial Organs (AREA)

Abstract

L'invention concerne une canule multilumière (1700) destinée à l'échange sanguin s'effectuant à l'intérieur de la vasculature d'un patient. La canule (1700) de l'invention comprend une première partie allongée (1702) définissant une première lumière (1704) et une seconde partie allongée (1706) définissant une seconde lumière (1708). La première partie allongée (1702) s'étend entre une première extrémité distale (1710) et une extrémité proximale (1714). La seconde partie allongée (1706) s'étend entre une seconde extrémité distale (1712) et l'extrémité proximale (1714). Au moins la première partie allongée (1702) ou la seconde partie allongée (1706) est configurée pour réduire la résistance à l'écoulement, à travers la canule.
EP05757823A 2004-06-10 2005-06-10 Canules et systeme presentant une resistance reduite a l'ecoulement Withdrawn EP1768722A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10/865,045 US20050277804A1 (en) 2004-06-10 2004-06-10 System including a cannula having reduced flow resistance
US10/866,535 US7445592B2 (en) 2004-06-10 2004-06-10 Cannulae having reduced flow resistance
US10/866,649 US20050277870A1 (en) 2004-06-10 2004-06-10 Cannula having reduced flow resistance
PCT/US2005/020663 WO2005123158A1 (fr) 2004-06-10 2005-06-10 Canules et systeme presentant une resistance reduite a l'ecoulement

Publications (1)

Publication Number Publication Date
EP1768722A1 true EP1768722A1 (fr) 2007-04-04

Family

ID=34971945

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05757823A Withdrawn EP1768722A1 (fr) 2004-06-10 2005-06-10 Canules et systeme presentant une resistance reduite a l'ecoulement

Country Status (2)

Country Link
EP (1) EP1768722A1 (fr)
WO (1) WO2005123158A1 (fr)

Families Citing this family (32)

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US7393181B2 (en) 2004-09-17 2008-07-01 The Penn State Research Foundation Expandable impeller pump
CA2646277C (fr) 2006-03-23 2016-01-12 The Penn State Research Foundation Dispositif d'assistance cardiaque avec une pompe a impulseur extensible
JP5757537B2 (ja) * 2009-06-04 2015-07-29 カーディオガード メディカル リミテッド 動脈装置、動脈系、および方法
WO2012094641A2 (fr) 2011-01-06 2012-07-12 Thoratec Corporation Pompe cardiaque percutanée
US9327067B2 (en) 2012-05-14 2016-05-03 Thoratec Corporation Impeller for catheter pump
US9872947B2 (en) 2012-05-14 2018-01-23 Tc1 Llc Sheath system for catheter pump
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