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EP1613318A4 - Composes et leur utilisation dans le traitement du diabete et troubles connexes - Google Patents

Composes et leur utilisation dans le traitement du diabete et troubles connexes

Info

Publication number
EP1613318A4
EP1613318A4 EP04758414A EP04758414A EP1613318A4 EP 1613318 A4 EP1613318 A4 EP 1613318A4 EP 04758414 A EP04758414 A EP 04758414A EP 04758414 A EP04758414 A EP 04758414A EP 1613318 A4 EP1613318 A4 EP 1613318A4
Authority
EP
European Patent Office
Prior art keywords
compounds
related disorders
treat diabetes
diabetes
treat
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP04758414A
Other languages
German (de)
English (en)
Other versions
EP1613318A2 (fr
Inventor
William H Bullock
Qingjie Liu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharmaceuticals Corp
Original Assignee
Bayer Pharmaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharmaceuticals Corp filed Critical Bayer Pharmaceuticals Corp
Publication of EP1613318A2 publication Critical patent/EP1613318A2/fr
Publication of EP1613318A4 publication Critical patent/EP1613318A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
EP04758414A 2003-03-26 2004-03-26 Composes et leur utilisation dans le traitement du diabete et troubles connexes Withdrawn EP1613318A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45819403P 2003-03-26 2003-03-26
PCT/US2004/009342 WO2004087880A2 (fr) 2003-03-26 2004-03-26 Composes et leur utilisation dans le traitement du diabete et troubles connexes

Publications (2)

Publication Number Publication Date
EP1613318A2 EP1613318A2 (fr) 2006-01-11
EP1613318A4 true EP1613318A4 (fr) 2009-03-11

Family

ID=33131765

Family Applications (1)

Application Number Title Priority Date Filing Date
EP04758414A Withdrawn EP1613318A4 (fr) 2003-03-26 2004-03-26 Composes et leur utilisation dans le traitement du diabete et troubles connexes

Country Status (3)

Country Link
EP (1) EP1613318A4 (fr)
JP (1) JP2006521400A (fr)
WO (1) WO2004087880A2 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040242566A1 (en) 2003-03-25 2004-12-02 Syrrx, Inc. Dipeptidyl peptidase inhibitors
JP2007511467A (ja) 2003-05-14 2007-05-10 タケダ サン ディエゴ インコーポレイテッド ジペプチジルペプチダーゼインヒビター
MXPA06001601A (es) 2003-08-13 2006-08-25 Takeda Pharmaceutical Derivados de 4-pirimidona y su uso como inhibidores de dipeptidilpeptidasa.
SI1942898T2 (sl) 2005-09-14 2014-08-29 Takeda Pharmaceutical Company Limited Dipeptidil-peptidazni inhibitorji za zdravljenje diabetesa
EP1924567B1 (fr) 2005-09-16 2012-08-22 Takeda Pharmaceutical Company Limited Inhibiteurs de dipeptidylpeptidase
WO2007112347A1 (fr) 2006-03-28 2007-10-04 Takeda Pharmaceutical Company Limited Inhibiteurs de la dipeptidyl peptidase
US8324383B2 (en) 2006-09-13 2012-12-04 Takeda Pharmaceutical Company Limited Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile
TW200838536A (en) 2006-11-29 2008-10-01 Takeda Pharmaceutical Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
US8093236B2 (en) 2007-03-13 2012-01-10 Takeda Pharmaceuticals Company Limited Weekly administration of dipeptidyl peptidase inhibitors
WO2020006018A1 (fr) 2018-06-27 2020-01-02 Bristol-Myers Squibb Company Composés de naphtyridinone substitués utiles en tant qu'activateurs de lymphocytes t
MX2020013373A (es) 2018-06-27 2021-03-09 Bristol Myers Squibb Co Compuestos de naftiridinona utiles como activadores de celulas t.
AR119821A1 (es) 2019-08-28 2022-01-12 Bristol Myers Squibb Co Compuestos de piridopirimidinonilo sustituidos útiles como activadores de células t
JP7712274B2 (ja) 2019-12-23 2025-07-23 ブリストル－マイヤーズ スクイブ カンパニー Ｔ細胞アクティベーターとして有用な置換ピペラジン誘導体
AR120823A1 (es) 2019-12-23 2022-03-23 Bristol Myers Squibb Co Compuestos bicíclicos sustituidos útiles como activadores de células t
KR20220119454A (ko) 2019-12-23 2022-08-29 브리스톨-마이어스 스큅 컴퍼니 T 세포 활성화제로서 유용한 치환된 퀴나졸리닐 화합물

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0779292A1 (fr) * 1994-08-29 1997-06-18 Yamanouchi Pharmaceutical Co. Ltd. Nouveau derive de naphtyridine et composition medicinale a base de ce derive
WO2005047285A1 (fr) * 2003-11-04 2005-05-26 Merck & Co., Inc. Derives de naphtyridinone substitues

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4350817A (en) * 1980-02-28 1982-09-21 American Home Products Corporation 4-Cl, Br or I-3-Carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives
JPH07126268A (ja) * 1993-10-29 1995-05-16 Otsuka Pharmaceut Factory Inc １，８−ナフチリジン誘導体

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0779292A1 (fr) * 1994-08-29 1997-06-18 Yamanouchi Pharmaceutical Co. Ltd. Nouveau derive de naphtyridine et composition medicinale a base de ce derive
WO2005047285A1 (fr) * 2003-11-04 2005-05-26 Merck & Co., Inc. Derives de naphtyridinone substitues

Also Published As

Publication number Publication date
WO2004087880A8 (fr) 2005-01-13
WO2004087880A3 (fr) 2005-03-10
JP2006521400A (ja) 2006-09-21
EP1613318A2 (fr) 2006-01-11
WO2004087880A2 (fr) 2004-10-14

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20051026

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL LT LV MK

DAX Request for extension of the european patent (deleted)
RBV Designated contracting states (corrected)

Designated state(s): DE ES FR GB IT

A4 Supplementary search report drawn up and despatched

Effective date: 20090206

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20090505