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EP1611147A4 - 6 "-AMINO-6" -DEOXYGALACTOSYLCERAMIDES - Google Patents

6 "-AMINO-6" -DEOXYGALACTOSYLCERAMIDES

Info

Publication number
EP1611147A4
EP1611147A4 EP03816701A EP03816701A EP1611147A4 EP 1611147 A4 EP1611147 A4 EP 1611147A4 EP 03816701 A EP03816701 A EP 03816701A EP 03816701 A EP03816701 A EP 03816701A EP 1611147 A4 EP1611147 A4 EP 1611147A4
Authority
EP
European Patent Office
Prior art keywords
deoxygalactosylceramides
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03816701A
Other languages
German (de)
French (fr)
Other versions
EP1611147A1 (en
Inventor
Paul B Savage
Albert Bendelac
Luc Teyton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brigham Young University
Original Assignee
Brigham Young University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham Young University filed Critical Brigham Young University
Publication of EP1611147A1 publication Critical patent/EP1611147A1/en
Publication of EP1611147A4 publication Critical patent/EP1611147A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18Acyclic radicals, substituted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP03816701A 2003-03-20 2003-03-20 6 "-AMINO-6" -DEOXYGALACTOSYLCERAMIDES Withdrawn EP1611147A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2003/008530 WO2004094444A1 (en) 2003-03-20 2003-03-20 6'-amino-6'-deoxygalactosylceramides

Publications (2)

Publication Number Publication Date
EP1611147A1 EP1611147A1 (en) 2006-01-04
EP1611147A4 true EP1611147A4 (en) 2007-10-17

Family

ID=33308974

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03816701A Withdrawn EP1611147A4 (en) 2003-03-20 2003-03-20 6 "-AMINO-6" -DEOXYGALACTOSYLCERAMIDES

Country Status (4)

Country Link
EP (1) EP1611147A4 (en)
AU (1) AU2003225891A1 (en)
CA (1) CA2519568C (en)
WO (1) WO2004094444A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1372668B1 (en) 2001-03-26 2011-12-07 Dana-Farber Cancer Institute, Inc. Method of attenuating reactions to skin irritants
US7645873B2 (en) 2003-03-20 2010-01-12 The Scripps Research Institute 6″-amino-6″-deoxygalactosylceramides
CA2584971C (en) 2004-11-02 2013-08-06 The Board Of Trustees Of The Leland Stanford Junior University Methods for inhibition of nkt cells
BRPI0607299A2 (en) 2005-01-28 2009-08-25 Univ Brigham Young activation of bacterial glycolipid from cd1d restricted nkt cells
US8227581B2 (en) * 2006-04-07 2012-07-24 The Scripps Research Institute Modified α-galactosyl ceramides for staining and stimulating natural killer T cells
WO2008005824A1 (en) 2006-06-30 2008-01-10 The Scripps Research Institute Adjuvants and methods of use
US8916164B2 (en) 2007-08-29 2014-12-23 Abivax Methods of enhancing adjuvaticity of vaccine compositions
EP2058011A1 (en) 2007-11-07 2009-05-13 Wittycell Nkt cell activating gycolipids covalently bound antigens and/or drug
EP2060252A1 (en) 2007-11-19 2009-05-20 Wittycell New formulation of galactosylceramide derivatives
EP2341931A1 (en) 2008-10-08 2011-07-13 Wittycell Vaccine composition for use against influenza
MY171201A (en) 2012-04-26 2019-10-01 Riken New carbamate glycolipid and use thereof
EP3296309B1 (en) * 2012-06-28 2019-08-07 Universiteit Gent Galactopyranosyl derivatives useful as medicaments
CN104736550B (en) 2012-07-26 2017-12-29 维多利亚联结有限公司 Organic compound
NZ708727A (en) * 2012-12-06 2019-09-27 Victoria Link Ltd Conjugate compounds
US10046046B2 (en) * 2014-06-05 2018-08-14 Victoria Link Limited Amino sphingoglycolipid analogues

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5936076A (en) * 1991-08-29 1999-08-10 Kirin Beer Kabushiki Kaisha αgalactosylceramide derivatives
TW261533B (en) * 1992-07-16 1995-11-01 Kirin Brewery

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ZHOU X-T ET AL: "Synthesis and NKT Cell Stimulating Properties of Fluorophore- and Biotin-Appended 6-Amino-6-deoxy-galactosylceramides", ORGANIC LETTERS, ACS, WASHINGTON, DC, US, vol. 4, no. 8, March 2002 (2002-03-01), pages 1267 - 1270, XP003008968, ISSN: 1523-7060 *

Also Published As

Publication number Publication date
WO2004094444A1 (en) 2004-11-04
EP1611147A1 (en) 2006-01-04
CA2519568C (en) 2012-01-03
CA2519568A1 (en) 2004-11-04
AU2003225891A1 (en) 2004-11-19

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20051020

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL LT LV MK

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20070917

RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 37/04 20060101ALI20070911BHEP

Ipc: C07H 15/18 20060101ALI20070911BHEP

Ipc: C07H 15/04 20060101ALI20070911BHEP

Ipc: A61K 31/7032 20060101AFI20070911BHEP

17Q First examination report despatched

Effective date: 20071129

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20080410