EP1578945A4 - Cct6s as modifiers of the rb pathway and methods of use - Google Patents

Cct6s as modifiers of the rb pathway and methods of use

Info

Publication number: EP1578945A4
Authority: EP; European Patent Office
Prior art keywords: cct6s; modifiers; pathway; methods
Prior art date: 2002-11-25
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP03789986A

Other languages

German (de)

French (fr)

Other versions

EP1578945A3 (en

EP1578945A2 (en

Inventor

Albert K Tai

Chunyan Song

Michael Martin Ollmann

Lucile A Gillett

Kim Lickteig

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Exelixis Inc

Original Assignee

Exelixis Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-11-25

Filing date

2003-11-24

Publication date

2006-09-27

2003-11-24 Application filed by Exelixis Inc filed Critical Exelixis Inc

2005-08-18 Publication of EP1578945A3 publication Critical patent/EP1578945A3/en

2005-09-28 Publication of EP1578945A2 publication Critical patent/EP1578945A2/en

2006-09-27 Publication of EP1578945A4 publication Critical patent/EP1578945A4/en

Status Withdrawn legal-status Critical Current

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Hematology (AREA)
Molecular Biology (AREA)
Urology & Nephrology (AREA)
Cell Biology (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Microbiology (AREA)
Pathology (AREA)
Biotechnology (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
Food Science & Technology (AREA)
General Physics & Mathematics (AREA)
Tropical Medicine & Parasitology (AREA)
Hospice & Palliative Care (AREA)
Oncology (AREA)
Bioinformatics & Cheminformatics (AREA)
Toxicology (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Investigating Or Analysing Biological Materials (AREA)

EP03789986A 2002-11-25 2003-11-24 Cct6s as modifiers of the rb pathway and methods of use Withdrawn EP1578945A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US42887202P	2002-11-25	2002-11-25
US428872P		2002-11-25
PCT/US2003/037548 WO2004048541A2 (en)	2002-11-25	2003-11-24	Cct6s as modifiers of the rb pathway and methods of use

Publications (3)

Publication Number	Publication Date
EP1578945A3 EP1578945A3 (en)	2005-08-18
EP1578945A2 EP1578945A2 (en)	2005-09-28
EP1578945A4 true EP1578945A4 (en)	2006-09-27

Family

ID=32393472

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP03789986A Withdrawn EP1578945A4 (en)	2002-11-25	2003-11-24	Cct6s as modifiers of the rb pathway and methods of use

Country Status (5)

Country	Link
EP (1)	EP1578945A4 (en)
JP (1)	JP4646631B2 (en)
AU (2)	AU2003294501B2 (en)
CA (1)	CA2506686A1 (en)
WO (2)	WO2004048536A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2798956A1 (en)	2007-04-23	2014-11-05	Stowers Institute for Medical Research	Methods and compositions for hematopoeitic stem cell self-renewal

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1997041433A1 (en) *	1996-04-29	1997-11-06	Cancer Research Campaign Technology Limited	METHOD AND MEANS FOR DISRUPTION OF p53 AND RB INTERACTION
WO1999041376A2 (en) *	1998-02-12	1999-08-19	Curagen Corporation	Retinoblastoma protein complexes and retinoblastoma interacting proteins
US6071715A (en) *	1993-08-12	2000-06-06	Board Of Regents, The University Of Texas System	Nucleic acids encoding novel proteins which bind to retinoblastoma protein

2003
- 2003-11-24 WO PCT/US2003/037538 patent/WO2004048536A2/en not_active Ceased
- 2003-11-24 CA CA002506686A patent/CA2506686A1/en not_active Abandoned
- 2003-11-24 AU AU2003294501A patent/AU2003294501B2/en not_active Ceased
- 2003-11-24 JP JP2004555682A patent/JP4646631B2/en not_active Expired - Fee Related
- 2003-11-24 EP EP03789986A patent/EP1578945A4/en not_active Withdrawn
- 2003-11-24 WO PCT/US2003/037548 patent/WO2004048541A2/en not_active Ceased
- 2003-11-24 AU AU2003294499A patent/AU2003294499A1/en not_active Abandoned

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6071715A (en) *	1993-08-12	2000-06-06	Board Of Regents, The University Of Texas System	Nucleic acids encoding novel proteins which bind to retinoblastoma protein
WO1997041433A1 (en) *	1996-04-29	1997-11-06	Cancer Research Campaign Technology Limited	METHOD AND MEANS FOR DISRUPTION OF p53 AND RB INTERACTION
WO1999041376A2 (en) *	1998-02-12	1999-08-19	Curagen Corporation	Retinoblastoma protein complexes and retinoblastoma interacting proteins

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DECAPRIO ET AL: "The Product of the Retinoblastoma Susceptibility Gene Has Properties of a Cell Cycle Regulatory Element", CELL, vol. 58, pages 1085 - 1095, XP008087857 *
FELDMAN DOUGLAS E ET AL: "Formation of the VHL-elongin BC tumor suppressor complex is mediated by the chaperonin TRiC", MOLECULAR CELL, vol. 4, no. 6, December 1999 (1999-12-01), pages 1051 - 1061, XP002394305, ISSN: 1097-2765 *
KUBOTA HIROSHI ET AL: "Structures and co-regulated expression of the genes encoding mouse cytosolic chaperonin CCT subunits", EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 262, no. 2, June 1999 (1999-06-01), pages 492 - 500, XP002394304, ISSN: 0014-2956 *
LI WEN-ZHUO ET AL: "Tcp20, a subunit of the eukaryotic TRiC chaperonin from humans and yeast", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 269, no. 28, 1994, pages 18616 - 18622, XP002394303, ISSN: 0021-9258 *

Also Published As

Publication number	Publication date
WO2004048541A2 (en)	2004-06-10
AU2003294501A1 (en)	2004-06-18
JP2006507005A (en)	2006-03-02
JP4646631B2 (en)	2011-03-09
AU2003294499A1 (en)	2004-06-18
AU2003294499A8 (en)	2004-06-18
EP1578945A2 (en)	2005-09-28
WO2004048541A3 (en)	2005-08-18
AU2003294501B2 (en)	2010-05-13
WO2004048536A2 (en)	2004-06-10
WO2004048536A3 (en)	2004-08-19
CA2506686A1 (en)	2004-06-10

Publication	Publication Date	Title
AU2003213606A8 (en)	2003-10-13	Mp53s as modifiers of the p53 pathway and methods of use
EP1401475A4 (en)	2005-05-11	Prmts as modifiers of the p53 pathway and methods of use
EP1466175A4 (en)	2008-04-09	SPHKs AS MODIFIERS OF THE p53 PATHWAY AND METHODS OF USE
EP1651956A4 (en)	2008-08-20	Melks as modifiers of the rac pathway and methods of use
AU2003272400A8 (en)	2004-04-30	Syts as modifiers of the p21 pathway and methods of use
EP1535067A4 (en)	2007-06-20	PAPSSs AS MODIFIERS OF THE AXIN PATHWAY AND METHODS OF USE
AU2003274911A8 (en)	2004-02-25	Mrbs as modifiers of the rb pathway and methods of use
AU2003295881A8 (en)	2004-06-18	Lamps as modifiers of the p53 pathway and methods of use
AU2003294499A8 (en)	2004-06-18	Rhebs as modifiers of the rb pathway and methods of use
AU2003251799A1 (en)	2004-01-23	Mchks as modifiers of the chk1 pathway and methods of use
AU2003303094A8 (en)	2004-08-13	Mat2as as modifiers of the p53 pathway and methods of use
AU2003251826A8 (en)	2004-01-23	Mp21s as modifiers of the p21 pathway and methods of use
EP1578945A3 (en)	2005-08-18	Cct6s as modifiers of the rb pathway and methods of use
AU2003265263A1 (en)	2004-01-23	ADCY3S AS MODIFIERS OF THE p21 PATHWAY AND METHODS OF USE
EP1587910A4 (en)	2008-08-27	Facls as modifiers of the rb pathway and methods of use
AU2003299990A8 (en)	2004-07-29	Mbcats as modifiers of the beta-catenin pathway and methods of use
AU2003217851A8 (en)	2003-09-16	Mbcats as modifiers of the beta-catenin pathway and methods of use
AU2003213665A8 (en)	2003-09-16	Lgals as modifiers of the chk pathway and methods of use
AU2003213693A8 (en)	2003-09-16	Mchks as modifiers of the chk pathway and methods of use
AU2002361654A8 (en)	2003-06-30	Mbcats as modifiers of the beta-catenin pathway and methods of use
AU2003258095A1 (en)	2004-02-25	MP21S AS MODIFIERS OF THE p21 PATHWAY AND METHODS OF USE
AU2003278811A8 (en)	2004-04-30	Ldlrs as modifiers of the p53 pathway and methods of use
AU2003213662A8 (en)	2003-09-16	Mbcats as modifiers of the beta-catenin pathway and methods of use
AU2003295928A8 (en)	2004-06-18	Mbcats as modifiers of the beta-catenin pathway and methods of use
EP1540333A4 (en)	2006-12-27	Maxs as modifiers of the axin pathway and methods of use

Legal Events

Date	Code	Title	Description
2005-08-12	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2005-08-19	PUAK	Availability of information related to the publication of the international search report	Free format text: ORIGINAL CODE: 0009015
2005-09-28	17P	Request for examination filed	Effective date: 20050511
2005-09-28	AK	Designated contracting states	Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
2005-09-28	AX	Request for extension of the european patent	Extension state: AL LT LV MK
2005-10-05	AK	Designated contracting states	Kind code of ref document: A3 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
2005-10-05	AX	Request for extension of the european patent	Extension state: AL LT LV MK
2005-10-12	RIC1	Information provided on ipc code assigned before grant	Ipc: 7A 01N 61/00 B Ipc: 7C 12Q 1/68 B Ipc: 7G 01N 33/53 B Ipc: 7G 01N 33/48 A
2006-09-20	RIC1	Information provided on ipc code assigned before grant	Ipc: A61K 49/00 20060101ALI20060817BHEP Ipc: C12Q 1/00 20060101AFI20060817BHEP
2006-09-27	A4	Supplementary search report drawn up and despatched	Effective date: 20060830
2006-12-27	RIN1	Information on inventor provided before grant (corrected)	Inventor name: LICKTEIG, KIM Inventor name: GILLETT, LUCILE, A. Inventor name: OLLMANN, MICHAEL, MARTIN Inventor name: SONG, CHUNYAN Inventor name: TAI, ALBERT, K.
2007-04-04	17Q	First examination report despatched	Effective date: 20070301
2012-10-26	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2012-11-28	18D	Application deemed to be withdrawn	Effective date: 20120601