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EP1578365A4 - Interactions moleculaires dans des neurones - Google Patents

Interactions moleculaires dans des neurones

Info

Publication number
EP1578365A4
EP1578365A4 EP03768964A EP03768964A EP1578365A4 EP 1578365 A4 EP1578365 A4 EP 1578365A4 EP 03768964 A EP03768964 A EP 03768964A EP 03768964 A EP03768964 A EP 03768964A EP 1578365 A4 EP1578365 A4 EP 1578365A4
Authority
EP
European Patent Office
Prior art keywords
neurons
molecular interactions
interactions
molecular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03768964A
Other languages
German (de)
English (en)
Other versions
EP1578365A2 (fr
Inventor
Peter S Lu
Jonathan David Garman
Michael P Belmares
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arbor Vita Corp
Original Assignee
Arbor Vita Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arbor Vita Corp filed Critical Arbor Vita Corp
Publication of EP1578365A2 publication Critical patent/EP1578365A2/fr
Publication of EP1578365A4 publication Critical patent/EP1578365A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Neurosurgery (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP03768964A 2002-11-14 2003-11-14 Interactions moleculaires dans des neurones Withdrawn EP1578365A4 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US42621202P 2002-11-14 2002-11-14
US42621302P 2002-11-14 2002-11-14
US426213P 2002-11-14
US426212P 2002-11-14
PCT/US2003/036698 WO2004045535A2 (fr) 2002-11-14 2003-11-14 Interactions moleculaires dans des neurones

Publications (2)

Publication Number Publication Date
EP1578365A2 EP1578365A2 (fr) 2005-09-28
EP1578365A4 true EP1578365A4 (fr) 2009-09-23

Family

ID=32329101

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03768964A Withdrawn EP1578365A4 (fr) 2002-11-14 2003-11-14 Interactions moleculaires dans des neurones

Country Status (3)

Country Link
EP (1) EP1578365A4 (fr)
CA (1) CA2505479A1 (fr)
WO (1) WO2004045535A2 (fr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6942981B1 (en) 1999-05-14 2005-09-13 Arbor Vita Corporation Method of determining interactions with PDZ-domain polypeptides
US8183339B1 (en) 1999-10-12 2012-05-22 Xigen S.A. Cell-permeable peptide inhibitors of the JNK signal transduction pathway
US20040082509A1 (en) 1999-10-12 2004-04-29 Christophe Bonny Cell-permeable peptide inhibitors of the JNK signal transduction pathway
DE10254601A1 (de) 2002-11-22 2004-06-03 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
CA2551190A1 (fr) * 2003-12-23 2005-07-07 Nono Inc. Polypeptides pour la modulation de la liaison des proteines du canal de recepteur de potentiel transitoire et proteines associees au recepteur de potentiel transitoire
DE102004024617A1 (de) 2004-05-18 2005-12-29 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
EP1910552A4 (fr) * 2005-06-23 2009-01-07 Arbor Vita Corp Procédés et compositions de modulation de la cox
US8080517B2 (en) 2005-09-12 2011-12-20 Xigen Sa Cell-permeable peptide inhibitors of the JNK signal transduction pathway
WO2007031098A1 (fr) 2005-09-12 2007-03-22 Xigen S.A. Inhibiteurs peptidiques permeables aux cellules de la voie de transduction de signal jnk
EP1790664A1 (fr) 2005-11-24 2007-05-30 Ganymed Pharmaceuticals AG Anticorps monoclonaux contre claudin-18 pour le traitement du cancer
US8633160B2 (en) * 2005-12-30 2014-01-21 Nono Inc. Small molecule inhibitors of PDZ interactions
US8685925B2 (en) * 2006-07-11 2014-04-01 Nono Inc. Method and compositions for treating stroke with fever
EP1884521A1 (fr) * 2006-07-31 2008-02-06 Xigen S.A. Peptide de fusion pour inhiber l'interaction du récepteur neuronal NMDA (NMDAR) avec les protéines interagissant avec le récepteur NMDA
US8008253B2 (en) 2007-07-03 2011-08-30 Andrew Tasker Treatment for anxiety
US8933013B2 (en) * 2007-12-05 2015-01-13 Nono Inc. Co-administration of an agent linked to an internalization peptide with an anti-inflammatory
WO2009143865A1 (fr) 2008-05-30 2009-12-03 Xigen S.A. Utilisation d'inhibiteurs peptidiques des voies de traduction du signal jnk perméables aux cellules pour le traitement de diverses maladies
WO2009143864A1 (fr) 2008-05-30 2009-12-03 Xigen S.A. Utilisation d'inhibiteurs peptidiques perméables aux cellules de la voie de transduction du signal jnk pour le traitement de maladies digestives inflammatoires chroniques ou non chroniques
WO2010072228A1 (fr) 2008-12-22 2010-07-01 Xigen S.A. Nouvelles constructions transporteuses et molécules conjuguées cargo/transporteuses
WO2010144721A2 (fr) * 2009-06-10 2010-12-16 Arbor Vita Corporation Systèmes modèles et régimes de traitement pour un traitement de maladies neurologiques
WO2011160653A1 (fr) 2010-06-21 2011-12-29 Xigen S.A. Nouvelles molécules inhibant jnk
US9150618B2 (en) 2010-10-14 2015-10-06 Xigen Inflammation Ltd. Use of cell-permeable peptide inhibitors of the JNK signal transduction pathway for the treatment of chronic or non-chronic inflammatory eye diseases
EP2581384A1 (fr) * 2011-10-11 2013-04-17 Institut Pasteur Produits utiles pour le traitement des tumeurs malignes du système nerveux humain
WO2013091670A1 (fr) 2011-12-21 2013-06-27 Xigen S.A. Nouvelles molécules inhibitrices de jnk pour le traitement de diverses maladies
WO2013167153A1 (fr) 2012-05-09 2013-11-14 Ganymed Pharmaceuticals Ag Anticorps utiles dans le diagnostic du cancer
WO2015197097A1 (fr) 2014-06-26 2015-12-30 Xigen Inflammation Ltd. Nouvelle utilisation pour des molécules inhibitrices de la jnk, pour le traitement de diverses maladies
WO2014206427A1 (fr) 2013-06-26 2014-12-31 Xigen Inflammation Ltd. Nouvelle utilisation d'inhibiteurs de peptides à perméabilité cellulaire dans la voie de transduction du signal jnk pour le traitement de diverses maladies
CN106554386A (zh) * 2015-09-25 2017-04-05 广州恒上医药技术有限公司 人乳头瘤病毒的表位肽及其应用
EP3723781B1 (fr) 2017-12-13 2024-12-11 The Research Foundation for the State University of New York Peptides et autres agents pour traiter la douleur et augmenter la sensibilité à la douleur
AU2019232759A1 (en) * 2018-03-08 2020-08-27 Phanes Therapeutics, Inc. Anti-TIP-1 antibodies and uses thereof
CN114807142B (zh) * 2022-05-26 2024-03-29 源生生物科技(青岛)有限责任公司 一种环状RNA-circ-Magi1及其应用

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2273622A1 (fr) * 1999-06-02 2000-12-02 Michael Tymianski Inhibition de la signalisation induite par le recepteur nmda dans le but de reduire les lesions neuronales
WO2002007751A1 (fr) * 2000-07-25 2002-01-31 Axcell Biosciences Corporation Identification et isolement de nouveaux polypeptides comportant des domaines pdz et leurs methodes d'utilisation
WO2002057413A2 (fr) * 2001-01-18 2002-07-25 The Board Of Trustees Of The Leland Stanford Junior University Peptides destines a l'activation et a l'inhibition de of delta pkc
WO2002090981A1 (fr) * 2001-05-08 2002-11-14 Japan Science And Technology Corporation Antigene antitumoral contre la contre la tumeur htlv-1 ou son epitope
WO2003014303A2 (fr) * 2001-08-03 2003-02-20 Arbor Vita Corporation Interactions moleculaires dans les cellules

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2273622A1 (fr) * 1999-06-02 2000-12-02 Michael Tymianski Inhibition de la signalisation induite par le recepteur nmda dans le but de reduire les lesions neuronales
WO2002007751A1 (fr) * 2000-07-25 2002-01-31 Axcell Biosciences Corporation Identification et isolement de nouveaux polypeptides comportant des domaines pdz et leurs methodes d'utilisation
WO2002057413A2 (fr) * 2001-01-18 2002-07-25 The Board Of Trustees Of The Leland Stanford Junior University Peptides destines a l'activation et a l'inhibition de of delta pkc
WO2002090981A1 (fr) * 2001-05-08 2002-11-14 Japan Science And Technology Corporation Antigene antitumoral contre la contre la tumeur htlv-1 ou son epitope
EP1391729A1 (fr) * 2001-05-08 2004-02-25 Japan Science and Technology Corporation Antigene antitumoral contre la contre la tumeur htlv-1 ou son epitope
WO2003014303A2 (fr) * 2001-08-03 2003-02-20 Arbor Vita Corporation Interactions moleculaires dans les cellules

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
AARTS MICHELLE ET AL: "Treatment of ischemic brain damage by perturbing NMDA receptor- PSD-95 protein interactions", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, US, WASHINGTON, DC, vol. 298, no. 5594, 25 October 2002 (2002-10-25), pages 846 - 850, XP002456870, ISSN: 0036-8075 *
KORNAU H-C ET AL: "Domain Interaction Between NMDA Receptor Subunits and the Postsynaptic Density Protein PSD-95", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, US, WASHINGTON, DC, vol. 269, no. 5231, 1 September 1995 (1995-09-01), pages 1737 - 1740, XP002196675, ISSN: 0036-8075 *
LIM I A ET AL: "Selectivity and promiscuity of the first and second PDZ domains of PSD-95 and synapse-associated protein 102", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOCHEMICAL BIOLOGISTS, BIRMINGHAM, US, vol. 277, no. 24, 14 June 2002 (2002-06-14), pages 21697 - 21698, XP002991766, ISSN: 0021-9258 *
ROUSSET R ET AL: "THE C-TERMINUS OF THE HTLV-1 TAX ONCOPROTEIN MEDIATES INTERACTION WITH THE PDZ DOMAIN OF CELLULAR PROTEINS", ONCOGENE, NATURE PUBLISHING GROUP, GB BASINGSTOKE, HANTS, vol. 16, no. 5, 5 February 1998 (1998-02-05), pages 643 - 654, XP000865909, ISSN: 0950-9232 *

Also Published As

Publication number Publication date
CA2505479A1 (fr) 2004-06-03
WO2004045535A2 (fr) 2004-06-03
WO2004045535A3 (fr) 2006-07-13
EP1578365A2 (fr) 2005-09-28

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