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EP1572218A4 - Anesthesique local a base d'une combinaison d'ester - Google Patents

Anesthesique local a base d'une combinaison d'ester

Info

Publication number
EP1572218A4
EP1572218A4 EP03800157A EP03800157A EP1572218A4 EP 1572218 A4 EP1572218 A4 EP 1572218A4 EP 03800157 A EP03800157 A EP 03800157A EP 03800157 A EP03800157 A EP 03800157A EP 1572218 A4 EP1572218 A4 EP 1572218A4
Authority
EP
European Patent Office
Prior art keywords
ester combination
local anesthesic
anesthesic
local
ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03800157A
Other languages
German (de)
English (en)
Other versions
EP1572218A2 (fr
Inventor
Steven L Shafer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leland Stanford Junior University
Original Assignee
Leland Stanford Junior University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leland Stanford Junior University filed Critical Leland Stanford Junior University
Publication of EP1572218A2 publication Critical patent/EP1572218A2/fr
Publication of EP1572218A4 publication Critical patent/EP1572218A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/625—Salicylic acid; Derivatives thereof having heterocyclic substituents, e.g. 4-salicycloylmorpholine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP03800157A 2002-12-20 2003-12-18 Anesthesique local a base d'une combinaison d'ester Withdrawn EP1572218A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32731002A 2002-12-20 2002-12-20
US327310 2002-12-20
PCT/US2003/041219 WO2004058329A2 (fr) 2002-12-20 2003-12-18 Anesthesique local a base d'une combinaison d'ester

Publications (2)

Publication Number Publication Date
EP1572218A2 EP1572218A2 (fr) 2005-09-14
EP1572218A4 true EP1572218A4 (fr) 2007-05-16

Family

ID=32680753

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03800157A Withdrawn EP1572218A4 (fr) 2002-12-20 2003-12-18 Anesthesique local a base d'une combinaison d'ester

Country Status (10)

Country Link
EP (1) EP1572218A4 (fr)
JP (1) JP2006513224A (fr)
KR (1) KR20050085736A (fr)
CN (1) CN1729004A (fr)
AU (1) AU2003299885A1 (fr)
BR (1) BR0317519A (fr)
CA (1) CA2507511A1 (fr)
MX (1) MXPA05006771A (fr)
NO (1) NO20053203L (fr)
WO (1) WO2004058329A2 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060062836A1 (en) * 2004-09-21 2006-03-23 Carter Stephen G Methods of device-assisted drug delivery
ATE537820T1 (de) 2005-03-15 2012-01-15 Animal Ethics Pty Ltd Topische analgetische zusammensetzung
ITMI20051633A1 (it) * 2005-09-06 2007-03-07 Sint Sa Nuovo uso di una composizione comprendente cloroprocaina hcl nuova composizione comprendente cloroprocaina hcl e metodo per la sua fabbricazione
JP2010500969A (ja) * 2006-07-19 2010-01-14 ファーマコフォア，インク． 麻酔薬
US20080220062A1 (en) * 2006-10-23 2008-09-11 Psivida, Inc. Sustained release of agents for localized pain management
US20110124685A1 (en) * 2008-01-18 2011-05-26 Jenkins Thomas E Anesthetic Compounds
ITMI20122120A1 (it) * 2012-12-12 2014-06-13 Sint Sa Composizione farmaceutica a base di cloroprocaina per la somministrazione intratecale ripetuta
ITCR20130004A1 (it) * 2013-02-05 2014-08-06 Vincenzo Vigna Farmaco salvavita
US10117847B2 (en) * 2015-12-04 2018-11-06 Ventis Pharma Extended duration local anesthetic formulation
DE102016215037B4 (de) 2016-08-11 2024-10-24 Lamello Ag Federvorrichtung und Verbindungsvorrichtung
US10792271B2 (en) * 2017-09-15 2020-10-06 Sintetica S.A. Topical formulations of chloroprocaine and methods of using same
WO2019226599A1 (fr) * 2018-05-22 2019-11-28 Alkalidx, Inc. Diagnostics et traitements de sujets insensibles à un anesthésique
JP6886551B1 (ja) * 2020-11-06 2021-06-16 医療法人祥和会 歯科用の局所麻酔液

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5446070A (en) * 1991-02-27 1995-08-29 Nover Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
WO2001030287A1 (fr) * 1999-10-25 2001-05-03 Epicept Corporation Prevention ou attenuation locale de la douleur occasionnee par des plaies fermees chirurgicalement
WO2001041550A2 (fr) * 1999-10-22 2001-06-14 Transdermatech, Inc. Formulation d'anesthesique topique
WO2001054679A2 (fr) * 2000-01-27 2001-08-02 Children's Hospital Research Foundation Composition d'anesthesique et de vasodilatateur transdermique et procedes pour son administration topique

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6326020B1 (en) * 1997-05-16 2001-12-04 Children's Medical Center Corporation Local anesthetic formulations

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5446070A (en) * 1991-02-27 1995-08-29 Nover Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
WO2001041550A2 (fr) * 1999-10-22 2001-06-14 Transdermatech, Inc. Formulation d'anesthesique topique
WO2001030287A1 (fr) * 1999-10-25 2001-05-03 Epicept Corporation Prevention ou attenuation locale de la douleur occasionnee par des plaies fermees chirurgicalement
WO2001054679A2 (fr) * 2000-01-27 2001-08-02 Children's Hospital Research Foundation Composition d'anesthesique et de vasodilatateur transdermique et procedes pour son administration topique

Also Published As

Publication number Publication date
BR0317519A (pt) 2005-11-16
CA2507511A1 (fr) 2004-07-15
WO2004058329A2 (fr) 2004-07-15
JP2006513224A (ja) 2006-04-20
EP1572218A2 (fr) 2005-09-14
AU2003299885A1 (en) 2004-07-22
WO2004058329A3 (fr) 2004-12-29
CN1729004A (zh) 2006-02-01
MXPA05006771A (es) 2005-09-08
NO20053203D0 (no) 2005-06-30
KR20050085736A (ko) 2005-08-29
NO20053203L (no) 2005-09-19

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 20050622

AK Designated contracting states

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Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL LT LV MK

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20070416

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20060201