EP1429747A4 - Preparation de noyau comprenant un hydrochlorure de pioglitazone et un biguanide - Google Patents

Preparation de noyau comprenant un hydrochlorure de pioglitazone et un biguanide

Info

Publication number: EP1429747A4
Authority: EP; European Patent Office
Prior art keywords: biguanide; pioglitazone hydrochloride; core formulation; formulation; core
Prior art date: 2001-07-10
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP01952548A

Other languages

German (de)

English (en)

Other versions

EP1429747A1 (fr

Inventor

Akwete L Adjei

Yaping Zhu

Anthony J Cutie

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Kos Life Sciences Inc

Original Assignee

Kos Life Sciences Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-07-10

Filing date

2001-07-10

Publication date

2005-01-05

2001-07-10 Application filed by Kos Life Sciences Inc filed Critical Kos Life Sciences Inc

2004-06-23 Publication of EP1429747A1 publication Critical patent/EP1429747A1/fr

2005-01-05 Publication of EP1429747A4 publication Critical patent/EP1429747A4/fr

Status Withdrawn legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/501—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Hematology (AREA)
Obesity (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Inorganic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)

EP01952548A 2001-07-10 2001-07-10 Preparation de noyau comprenant un hydrochlorure de pioglitazone et un biguanide Withdrawn EP1429747A4 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/US2001/021615 WO2003005995A1 (fr)	2001-07-10	2001-07-10	Preparation de noyau comprenant un hydrochlorure de pioglitazone et un biguanide

Publications (2)

Publication Number	Publication Date
EP1429747A1 EP1429747A1 (fr)	2004-06-23
EP1429747A4 true EP1429747A4 (fr)	2005-01-05

Family

ID=21742689

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP01952548A Withdrawn EP1429747A4 (fr)	2001-07-10	2001-07-10	Preparation de noyau comprenant un hydrochlorure de pioglitazone et un biguanide

Country Status (6)

Country	Link
EP (1)	EP1429747A4 (fr)
JP (1)	JP2004536843A (fr)
AU (1)	AU2001273289B2 (fr)
CA (1)	CA2453775A1 (fr)
MX (1)	MXPA04000180A (fr)
WO (1)	WO2003005995A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2001273310B2 (en) *	2001-07-10	2004-10-07	Kos Life Sciences, Inc.	A core formulation
CA2492722A1 (fr) *	2002-07-11	2004-01-22	Takeda Pharmaceutical Company Limited	Procede de production d'une preparation recouverte
AU2004208606B2 (en)	2003-01-29	2009-09-24	Takeda Pharmaceutical Company Limited	Process for producing coated preparation
GB0316940D0 (en) *	2003-07-19	2003-08-27	Ward Warren	Treatment of skin and other medical conditions
AU2004262969B2 (en) *	2003-07-19	2010-08-12	Warren Ward	Compositions comprising components coated with a liquid impermeable but gas permeable layer, use thereof for treating cutaneous and other exocrine gland diseases
US20070078170A1 (en) *	2003-08-28	2007-04-05	Khanduri Chandra H	Process for the preparation of pioglitazone
WO2006076191A2 (fr) *	2005-01-10	2006-07-20	Elc Management Llc	Revetement de surface discontinue pour particules
MXPA05014092A (es) *	2005-12-20	2007-06-20	Leopoldo De Jesus Espinosa Abdala	Composiciones farmaceuticas que comprenden sustancias derivadas de la tiazolidinedionas combinadas con una biguanida para su uso en diabetes mellitus tipo 2.

Citations (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1997041842A1 (fr) *	1996-05-09	1997-11-13	The Trustees Of The University Of Pennsylvania	Particules creuses contenant du calcium et du phosphate du type mineral et destinees a un tissu osseux___________________________
WO1999003477A1 (fr) *	1997-07-18	1999-01-28	Smithkline Beecham P.L.C.	Traitement du diabete avec du thiazolidinedione, un secretagogue d'insuline et du biguanide
US6011049A (en) *	1997-02-19	2000-01-04	Warner-Lambert Company	Combinations for diabetes
WO2000044681A2 (fr) *	1999-02-01	2000-08-03	The Curators Of The University Of Missouri	Procede de preparation de coques ou de gels a partir de particules de verre
WO2001082875A2 (fr) *	2000-05-01	2001-11-08	Aeropharm Technology, Inc.	Formulation de noyau
WO2003005993A1 (fr) *	2000-05-01	2003-01-23	Aeropharm Technology Incorporated	Formulation de noyau comprenant de la troglitazone et un biguanide
WO2003005991A1 (fr) *	2001-07-10	2003-01-23	Aeropharm Technology Incorporated	Formulation de noyau

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TWI238064B (en) *	1995-06-20	2005-08-21	Takeda Chemical Industries Ltd	A pharmaceutical composition for prophylaxis and treatment of diabetes

2001
- 2001-07-10 CA CA002453775A patent/CA2453775A1/fr not_active Abandoned
- 2001-07-10 JP JP2003511802A patent/JP2004536843A/ja active Pending
- 2001-07-10 WO PCT/US2001/021615 patent/WO2003005995A1/fr not_active Ceased
- 2001-07-10 AU AU2001273289A patent/AU2001273289B2/en not_active Ceased
- 2001-07-10 EP EP01952548A patent/EP1429747A4/fr not_active Withdrawn
- 2001-07-10 MX MXPA04000180A patent/MXPA04000180A/es unknown

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1997041842A1 (fr) *	1996-05-09	1997-11-13	The Trustees Of The University Of Pennsylvania	Particules creuses contenant du calcium et du phosphate du type mineral et destinees a un tissu osseux___________________________
US6011049A (en) *	1997-02-19	2000-01-04	Warner-Lambert Company	Combinations for diabetes
WO1999003477A1 (fr) *	1997-07-18	1999-01-28	Smithkline Beecham P.L.C.	Traitement du diabete avec du thiazolidinedione, un secretagogue d'insuline et du biguanide
WO2000044681A2 (fr) *	1999-02-01	2000-08-03	The Curators Of The University Of Missouri	Procede de preparation de coques ou de gels a partir de particules de verre
WO2001082875A2 (fr) *	2000-05-01	2001-11-08	Aeropharm Technology, Inc.	Formulation de noyau
WO2003005993A1 (fr) *	2000-05-01	2003-01-23	Aeropharm Technology Incorporated	Formulation de noyau comprenant de la troglitazone et un biguanide
WO2003005991A1 (fr) *	2001-07-10	2003-01-23	Aeropharm Technology Incorporated	Formulation de noyau

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO03005995A1 *

Also Published As

Publication number	Publication date
WO2003005995A1 (fr)	2003-01-23
MXPA04000180A (es)	2004-11-22
CA2453775A1 (fr)	2003-01-23
AU2001273289B2 (en)	2004-10-07
EP1429747A1 (fr)	2004-06-23
JP2004536843A (ja)	2004-12-09

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GB2406697B (en)	2006-02-22	Gaming device having a first and second game
EP1455793A4 (fr)	2007-03-07	Formulation anti-diabete et procede
IL158437A0 (en)	2004-05-12	Absorbent article having a multilayer absorbent core
EP1312281A4 (fr)	2009-04-29	Procede et dispositif de fabrication d'une brosse
AU2002337749A1 (en)	2003-04-07	Pioglitazone hydrochloride
AU2003272504A8 (en)	2004-04-08	Multistage formulation containing a biguanide and thiazolidindione derivatives
AU2001227535A1 (en)	2001-11-12	A core formulation
AU2001227532A1 (en)	2001-11-12	A core formulation
EP1429747A4 (fr)	2005-01-05	Preparation de noyau comprenant un hydrochlorure de pioglitazone et un biguanide
TWI315982B (en)	2009-10-21	Combinations comprising epothilones and pharmaceutical uses thereof
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EP1511753A4 (fr)	2005-10-12	Antimicrobiens et leurs utilisations
GB0111723D0 (en)	2001-07-04	A pillow
AU2001273309A1 (en)	2003-01-29	Core formulation comprising troglitazone and a biguanide
GB0101992D0 (en)	2001-03-14	Pesticidal formulation
SG104988A1 (en)	2004-07-30	Leadframe and component with a leadframe
IL147063A0 (en)	2002-08-14	Pesticidal formulation
AU2001269849A1 (en)	2001-12-24	A package and methods of manufacturing and using same
EP1429740A4 (fr)	2005-01-26	Formulation de noyau comprenant de la troglitazone et un biguanide
GB2372253B (en)	2005-07-13	A render
GB0102050D0 (en)	2001-03-14	A puzzle
GB2384987B (en)	2004-06-09	A head lice formulation
GB0030802D0 (en)	2001-01-31	Packaging regimen of pseudoephedrine hydrochloride and fexofenadine hydrochloride

Legal Events

Date	Code	Title	Description
2004-05-07	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2004-06-23	17P	Request for examination filed	Effective date: 20040109
2004-06-23	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
2004-06-23	AX	Request for extension of the european patent	Extension state: AL LT LV MK RO SI
2005-01-05	A4	Supplementary search report drawn up and despatched	Effective date: 20041122
2005-01-05	RIC1	Information provided on ipc code assigned before grant	Ipc: 7A 61K 9/50 B Ipc: 7A 61K 31/4439 B Ipc: 7A 61K 31/155 B Ipc: 7A 61K 9/16 A
2005-05-11	17Q	First examination report despatched	Effective date: 20050323
2006-07-14	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2006-08-16	18D	Application deemed to be withdrawn	Effective date: 20060131