EP1487965A4 - Minicell compositions and methods - Google Patents
Minicell compositions and methodsInfo
- Publication number
- EP1487965A4 EP1487965A4 EP02747872A EP02747872A EP1487965A4 EP 1487965 A4 EP1487965 A4 EP 1487965A4 EP 02747872 A EP02747872 A EP 02747872A EP 02747872 A EP02747872 A EP 02747872A EP 1487965 A4 EP1487965 A4 EP 1487965A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- methods
- minicell compositions
- minicell
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/5432—Liposomes or microcapsules
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/60—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Physics & Mathematics (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20110000796 EP2390308A1 (en) | 2002-02-25 | 2002-05-28 | Minicell compositions and methods |
| EP10008869.9A EP2272946B9 (en) | 2002-02-25 | 2002-05-28 | Minicell compositions and methods |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US154951 | 1988-02-10 | ||
| US35984302P | 2002-02-25 | 2002-02-25 | |
| US359843P | 2002-02-25 | ||
| US10/154,951 US20030194798A1 (en) | 2001-05-24 | 2002-05-24 | Minicell compositions and methods |
| PCT/US2002/016877 WO2003072014A2 (en) | 2002-02-25 | 2002-05-28 | Minicell compositions and methods |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP10008869.9A Division EP2272946B9 (en) | 2002-02-25 | 2002-05-28 | Minicell compositions and methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP1487965A2 EP1487965A2 (en) | 2004-12-22 |
| EP1487965A4 true EP1487965A4 (en) | 2006-11-15 |
Family
ID=27767433
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP10008869.9A Revoked EP2272946B9 (en) | 2002-02-25 | 2002-05-28 | Minicell compositions and methods |
| EP02747872A Withdrawn EP1487965A4 (en) | 2002-02-25 | 2002-05-28 | Minicell compositions and methods |
| EP20110000796 Withdrawn EP2390308A1 (en) | 2002-02-25 | 2002-05-28 | Minicell compositions and methods |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP10008869.9A Revoked EP2272946B9 (en) | 2002-02-25 | 2002-05-28 | Minicell compositions and methods |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP20110000796 Withdrawn EP2390308A1 (en) | 2002-02-25 | 2002-05-28 | Minicell compositions and methods |
Country Status (5)
| Country | Link |
|---|---|
| EP (3) | EP2272946B9 (en) |
| AU (1) | AU2002318168B2 (en) |
| CA (1) | CA2517027A1 (en) |
| ES (1) | ES2541351T3 (en) |
| WO (1) | WO2003072014A2 (en) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7117033B2 (en) | 2000-05-08 | 2006-10-03 | Brainsgate, Ltd. | Stimulation for acute conditions |
| US20030194798A1 (en) | 2001-05-24 | 2003-10-16 | Surber Mark W. | Minicell compositions and methods |
| US7396822B2 (en) | 2001-05-24 | 2008-07-08 | Vaxiion Therapeutics, Inc. | Immunogenic minicells and methods of use |
| WO2003033519A2 (en) * | 2001-10-15 | 2003-04-24 | Engeneic Gene Therapy Pty Limited | Intact minicells as vectors for dna transfer and gene therapy in vitro and in vivo |
| US7561919B2 (en) | 2002-11-14 | 2009-07-14 | Brainsgate Ltd. | SPG stimulation via the greater palatine canal |
| US7611885B2 (en) | 2003-06-24 | 2009-11-03 | Engeneic Molecular Delivery Pty, Ltd. | Pharmaceutically compatible method for purifying intact bacterial minicells |
| CA2549840C (en) | 2003-12-09 | 2012-03-20 | Engeneic Molecular Delivery Pty Ltd. | Targeted gene delivery to non-phagocytic mammalian cells via bacterially derived intact minicells |
| US8772013B2 (en) | 2004-02-02 | 2014-07-08 | Engeneic Molecular Delivery Pty Ltd | Methods for targeted in vitro and in vivo drug delivery to mammalian cells via bacterially derived intact minicells |
| SI1718338T1 (en) | 2004-02-02 | 2015-09-30 | Engeneic Molecular Delivery Pty Ltd. | Compositions and methods for targeted in vitro and in vivo drug delivery to mammalian cells via bacterially derived intact minicells |
| JP4114075B2 (en) * | 2004-02-16 | 2008-07-09 | ヒューマン・メタボローム・テクノロジーズ株式会社 | Method for identifying function of gene product and method for identifying binding substance |
| US9233245B2 (en) | 2004-02-20 | 2016-01-12 | Brainsgate Ltd. | SPG stimulation |
| US8010189B2 (en) | 2004-02-20 | 2011-08-30 | Brainsgate Ltd. | SPG stimulation for treating complications of subarachnoid hemorrhage |
| US8055347B2 (en) | 2005-08-19 | 2011-11-08 | Brainsgate Ltd. | Stimulation for treating brain events and other conditions |
| US20060002956A1 (en) * | 2004-04-05 | 2006-01-05 | Surber Mark W | Minicells as vaccines |
| MX2007002294A (en) | 2004-08-26 | 2007-10-19 | Engeneic Molecular Delivery Pty Ltd | Delivering functional nucleic acids to mammalian cells via bacterially derived, intact minicells. |
| PL2040725T3 (en) | 2006-06-23 | 2014-08-29 | Engeneic Molecular Delivery Pty Ltd | Targeted delivery of drugs, therapeutic nucleic acids and functional nucleic acids to mammalian cells via intact killed bacterial cells |
| ES2720659T3 (en) | 2011-02-15 | 2019-07-23 | Vaxiion Therapeutics Llc | Therapeutic compositions and methods for the directed administration, by means of bacterial mini-cells, of bioactive molecules based on targeted molecules containing Fc and antibodies |
| US20140342932A1 (en) * | 2011-09-23 | 2014-11-20 | Merck Sharp & Dohme Corp. | Functional cell surface display of ligands for the insulin and/or insulin growth factor 1 receptor and applications thereof |
| US9675796B2 (en) | 2013-11-10 | 2017-06-13 | Brainsgate Ltd. | Implant and delivery system for neural stimulator |
| RU2577138C1 (en) * | 2014-11-25 | 2016-03-10 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) | Method of producing of recombinant protein sav-rgd |
| EP3093043B1 (en) | 2015-05-13 | 2018-11-14 | Brainsgate Ltd. | Implant and delivery system for neural stimulator |
| CN110546250A (en) | 2017-04-28 | 2019-12-06 | 农业球体公司 | Compositions and methods for encapsulation and scalable delivery of agrochemicals |
| MX2020003074A (en) | 2017-09-25 | 2020-09-14 | Agrospheres Inc | Compositions and methods for scalable production and delivery of biologicals. |
| TW202012616A (en) | 2018-09-28 | 2020-04-01 | 日商住友化學股份有限公司 | Microorganism preparation for decomposing bacteria, target microorganisms, decomposition method of target microorganisms, decomposition device of target microorganisms |
| SG11202107306WA (en) | 2019-01-04 | 2021-08-30 | Engeneic Molecular Delivery Pty Ltd | Encapsulated glycolipid antigens for treatment of neoplastic diseases |
| CN110669811A (en) * | 2019-10-21 | 2020-01-10 | 天津大学 | Method for improving surfactant yield |
| MX2022010917A (en) * | 2020-03-06 | 2022-11-30 | Endolytix Tech Inc | Compositions and methods for the treatment of intracellular bacterial infections. |
| CN116087504B (en) * | 2023-02-24 | 2023-08-15 | 上海碧云天生物技术有限公司 | Immune magnetic bead protection liquid, preparation method and application thereof |
| CN119689002B (en) * | 2025-02-25 | 2025-06-06 | 山东大学 | Biomarker combination for predicting embryo repeated planting failure, kit and application thereof, and combined medicine and application thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003033519A2 (en) * | 2001-10-15 | 2003-04-24 | Engeneic Gene Therapy Pty Limited | Intact minicells as vectors for dna transfer and gene therapy in vitro and in vivo |
Family Cites Families (83)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4132769A (en) | 1974-10-30 | 1979-01-02 | Osther Kurt B | Cancer antigen, cancer therapy, and cancer diagnosis |
| US4237224A (en) | 1974-11-04 | 1980-12-02 | Board Of Trustees Of The Leland Stanford Jr. University | Process for producing biologically functional molecular chimeras |
| US5212071A (en) | 1988-04-01 | 1993-05-18 | The Johns Hopkins University | Nucleic acids encoding a human C3b/C4b receptor (CR1) |
| US4190495A (en) | 1976-09-27 | 1980-02-26 | Research Corporation | Modified microorganisms and method of preparing and using same |
| US4311797A (en) | 1979-09-18 | 1982-01-19 | University Of Saskatchewan | Anucleated live E. coli vaccine |
| US4497796A (en) | 1980-03-26 | 1985-02-05 | The Regents Of The University Of California | Gene transfer in intact mammals |
| US4895724A (en) | 1985-06-07 | 1990-01-23 | Pfizer Inc. | Chitosan compositions for controlled and prolonged release of macromolecules |
| US4839293A (en) | 1986-02-24 | 1989-06-13 | The Trustees Of Columbia University In The City Of New York | DNA encoding streptavidin, streptavidin produced therefrom, fused polypeptides which include amino acid sequences present in streptavidin and uses thereof |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5260203A (en) | 1986-09-02 | 1993-11-09 | Enzon, Inc. | Single polypeptide chain binding molecules |
| US5869620A (en) | 1986-09-02 | 1999-02-09 | Enzon, Inc. | Multivalent antigen-binding proteins |
| US4921790A (en) | 1987-04-24 | 1990-05-01 | Research Corporation | Tumor specific assay for CA125 ovarian cancer antigen |
| US5654176A (en) | 1987-05-28 | 1997-08-05 | Amrad Corporation Limited | Fusion proteins containing glutathione-s-transferase |
| US4963484A (en) | 1988-01-29 | 1990-10-16 | Dana-Farber Cancer Institute, Inc. | Genetically engineered polypeptides with determinants of the human DF3 breast carcinoma-associated antigen |
| US5053489A (en) | 1988-01-29 | 1991-10-01 | Dana-Farber Cancer Institute, Inc. | Genetically engineered polypeptides with determinants of the human DF3 breast carcinoma-associated antigen |
| US4914021A (en) | 1988-03-04 | 1990-04-03 | New England Deaconess Hospital Corporation | Carcinoma orosomucoid-related antigen, a monoclonal antibody thereto, and their uses |
| US6307030B1 (en) | 1988-04-15 | 2001-10-23 | The University Of North Carolina At Chapel Hill | Androgen receptor proteins, recombinant DNA molecules coding for such, and use of such compositions |
| ATE197067T1 (en) | 1989-04-07 | 2000-11-15 | Cancerforskningsfonden Af 1989 | UROKINASE TYPE PLASMINOGEN ACTIVATOR RECEPTOR |
| US6261800B1 (en) | 1989-05-05 | 2001-07-17 | Genentech, Inc. | Luteinizing hormone/choriogonadotropin (LH/CG) receptor |
| US5260432A (en) | 1989-06-22 | 1993-11-09 | Sloan-Kettering Institute For Cancer Research | Human gamma retinoic acid receptor DNA |
| US5804604A (en) | 1989-12-21 | 1998-09-08 | Biogen, Inc. | Tat-derived transport polypeptides and fusion proteins |
| US5652122A (en) | 1989-12-21 | 1997-07-29 | Frankel; Alan | Nucleic acids encoding and methods of making tat-derived transport polypeptides |
| US5773024A (en) | 1989-12-22 | 1998-06-30 | Imarx Pharmaceutical Corp. | Container with multi-phase composition for use in diagnostic and therapeutic applications |
| JP3949711B2 (en) | 1990-02-26 | 2007-07-25 | ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ | Identification and expression of insect steroid receptor DNA sequences |
| EP0475292B1 (en) | 1990-09-10 | 1999-06-30 | Takeda Chemical Industries, Ltd. | Human luteinizing hormone-human chorionic gonadotropin receptor (Human LH/hCG receptor) |
| US5314695A (en) | 1990-11-13 | 1994-05-24 | Corvas International, Inc. | Tissue factor based prothrombin time reagent |
| US5840867A (en) | 1991-02-21 | 1998-11-24 | Gilead Sciences, Inc. | Aptamer analogs specific for biomolecules |
| JP3050424B2 (en) | 1991-07-12 | 2000-06-12 | 塩野義製薬株式会社 | Human endothelin receptor |
| US6027725A (en) | 1991-11-25 | 2000-02-22 | Enzon, Inc. | Multivalent antigen-binding proteins |
| GB2265375A (en) | 1992-03-16 | 1993-09-29 | Merck & Co Inc | Human nuerokinin-3 receptor |
| US6225080B1 (en) | 1992-03-23 | 2001-05-01 | George R. Uhl | Mu-subtype opioid receptor |
| US5532347A (en) | 1992-04-10 | 1996-07-02 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University, A Non-Profit Organization | DNA encoding α melanocyte stimulating hormone receptor |
| US5837521A (en) | 1993-04-08 | 1998-11-17 | State Of Oregon | Nucleic acids encoding the γ-MSH receptor MC3-R |
| US6313279B1 (en) | 1992-05-01 | 2001-11-06 | Eli Lilly And Company | Human glutamate receptor and related DNA compounds |
| FR2692592B1 (en) | 1992-06-19 | 1995-03-31 | Pasteur Merieux Serums Vacc | DNA fragments encoding the Neisseria meningitidis transferrin receptor subunits and methods of expressing them. |
| JP4208960B2 (en) | 1992-08-13 | 2009-01-14 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | Opioid receptor gene |
| US6300087B1 (en) | 1992-11-03 | 2001-10-09 | Synaptic Pharmaceutical Corporation | DNA encoding a human serotonin receptor (5-HT4B) and uses thereof |
| CA2149889A1 (en) | 1992-11-20 | 1994-06-09 | Ralph C. Dornburg | Cell-type specific gene transfer using retroviral vectors containing antibody-envelope fusion proteins |
| WO1994018562A1 (en) | 1993-02-05 | 1994-08-18 | Epigen, Inc. | Human carcinoma antigen (hca), hca antibodies, hca immunoassays, methods of imaging and therapy |
| US6258556B1 (en) | 1993-02-26 | 2001-07-10 | The United States Of America As Represented By The Department Of Health And Human Services | cDNA and genomic clones encoding human μ opiate receptor and the purified gene product |
| US6235496B1 (en) | 1993-03-08 | 2001-05-22 | Advanced Research & Technology Institute | Nucleic acid encoding mammalian mu opioid receptor |
| GB2286188B (en) | 1993-04-20 | 1997-11-12 | Salk Inst Biotech Ind | Human N-methyl-D-aspartate receptor subunits,nucleic acids encoding same and uses therefor |
| US5763575A (en) | 1993-07-26 | 1998-06-09 | Cor Therapeutics, Inc. | Agonist and antagonist peptides of the C140 receptor |
| US6291206B1 (en) | 1993-09-17 | 2001-09-18 | Genetics Institute, Inc. | BMP receptor proteins |
| FI961251A0 (en) | 1993-09-20 | 1996-03-18 | Ciba Geigy | Human metabotropic glutamate receptor subtypes (HMR4, HMR6, HMR7) and to these related DNA compounds |
| DE69434839T2 (en) | 1993-11-08 | 2007-10-25 | Sanofi Pasteur Ltd., Toronto | TRANSFERRINE RECEPTOR GENES FROM HAEMOPHILUS |
| US6248554B1 (en) | 1993-11-24 | 2001-06-19 | The Procter & Gamble Company | DNA sequence coding for a BMP receptor |
| US6225531B1 (en) | 1994-06-17 | 2001-05-01 | Kirin Beer Kabushiki Kaisha | Glucan elicitor receptor, DNA molecule coding therefor, fungus-resistant plants transformed with the DNA molecule and method for creating the plants |
| GB9416536D0 (en) | 1994-08-16 | 1994-10-12 | Karobio Ab | Orphan receptor |
| JP3949715B2 (en) | 1994-09-05 | 2007-07-25 | アムラド・オペレイションズ・プロプライエタリー・リミテッド | Novel hemopoietin receptor |
| US6306622B1 (en) | 1994-11-04 | 2001-10-23 | The Procter & Gamble Co. | cDNA encoding a BMP type II receptor |
| US6245893B1 (en) | 1994-12-17 | 2001-06-12 | Smithkline Beecham P.L.C. | Receptor that binds anti-convulsant compounds |
| JP3064015B2 (en) | 1995-01-26 | 2000-07-12 | メルク フロスト カナダ アンド カンパニー | Prostaglandin receptor DP |
| US6111079A (en) | 1995-06-05 | 2000-08-29 | Bionebraska, Inc. | Lead binding polypeptides and nucleotides coding therefore |
| US6025191A (en) | 1995-06-07 | 2000-02-15 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules which encode a melanoma specific antigen and uses thereof |
| US6291207B1 (en) | 1995-07-28 | 2001-09-18 | Northwestern University | Herpes virus entry receptor protein |
| US6290970B1 (en) | 1995-10-11 | 2001-09-18 | Aventis Pasteur Limited | Transferrin receptor protein of Moraxella |
| US6017721A (en) | 1995-10-18 | 2000-01-25 | The United States Of America As Represented By The Department Of Health And Human Services | Chromatographic method and device for preparing blood serum for compatibility testing |
| US6048539A (en) | 1995-11-02 | 2000-04-11 | Connaught Laboratories Limited | Lactoferrin receptor protein |
| US6265184B1 (en) | 1995-12-20 | 2001-07-24 | Icos Corporation | Polynucleotides encoding chemokine receptor 88C |
| US6268214B1 (en) | 1996-04-04 | 2001-07-31 | Roche Diagnostics Gmbh | Vectors encoding a modified low affinity nerve growth factor receptor |
| US5965392A (en) | 1996-04-08 | 1999-10-12 | Bayer Corporation | Neuropeptide Y receptor Y5 and nucleic acid sequences |
| US6271347B1 (en) | 1996-04-26 | 2001-08-07 | Merck & Co., Inc. | Eosinophil eotaxin receptor |
| US6258944B1 (en) | 1996-05-06 | 2001-07-10 | Merck & Co., Inc. | OB receptor isoforms and nucleic acids encoding them |
| WO1998011221A2 (en) | 1996-09-13 | 1998-03-19 | Dana-Farber Cancer Institute | Car, a novel coxsackievirus and adenovirus receptor |
| JP2001508293A (en) | 1996-12-27 | 2001-06-26 | メルク エンド カンパニー インコーポレーテッド | Mouse galanin receptor GALR2 and nucleotides encoding the receptor |
| ATE321855T1 (en) | 1997-01-14 | 2006-04-15 | Human Genome Sciences Inc | TUMOR NECROSIS FACTOR RECEPTOR 5 |
| US6017735A (en) | 1997-01-23 | 2000-01-25 | Marie Curie Cancer Care | Materials and methods for intracellular transport and their uses |
| US6242251B1 (en) | 1997-03-18 | 2001-06-05 | Eli Lilly And Company | Rhesus neuropeptide Y5 receptor |
| AU6769998A (en) | 1997-03-26 | 1998-10-20 | Board Of Regents, The University Of Texas System | Methods and compositions for using membrane-penetrating proteins to carry materials across cell membranes |
| JP3885177B2 (en) | 1997-03-26 | 2007-02-21 | 大塚製薬株式会社 | Human gene |
| US5951951A (en) | 1997-04-30 | 1999-09-14 | Medtronic, Inc. | Platelet function evaluation technique for citrated whole blood |
| GB9710699D0 (en) | 1997-05-24 | 1997-07-16 | Danbiosyst Uk | Gastro-retentive controlled release system |
| DE69819345T2 (en) | 1997-08-20 | 2004-07-15 | The Regents Of The University Of California, Oakland | NUCLEIC ACID SEQUENCES ENCODING THE CAPSAICIN RECEPTOR AND POLYPEPTIDES SIMILAR TO THE CAPSAICIN RECEPTOR AND THEIR USE |
| US6222015B1 (en) | 1997-09-08 | 2001-04-24 | Merck & Co., Inc. | Estrogen receptor |
| ATE362983T1 (en) | 1997-11-11 | 2007-06-15 | Ono Pharmaceutical Co | HUMAN LYSOPHOSPHATIDIC ACID RECEPTOR AND USE THEREOF |
| US6210967B1 (en) | 1997-12-10 | 2001-04-03 | Synaptic Pharmaceutical Corporation | DNA encoding a mammalian LPA receptor and uses thereof |
| DE69941187D1 (en) | 1998-06-01 | 2009-09-10 | Agensys Inc | SERPENTINTRANSMEMBRANANTIGENE EXPRESSED IN HUMAN CANCER AND ITS USES |
| US6248520B1 (en) | 1998-07-06 | 2001-06-19 | The Rockefeller University | Nucleic acid molecules encoding nuclear hormone receptor coactivators and uses thereof |
| US6221613B1 (en) | 1998-12-31 | 2001-04-24 | Synaptic Pharmaceutical Corporation | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof |
| US6221660B1 (en) | 1999-02-22 | 2001-04-24 | Synaptic Pharmaceutical Corporation | DNA encoding SNORF25 receptor |
| US7125679B2 (en) | 2001-03-07 | 2006-10-24 | Children's Medical Center Corporation | Methods to screen peptide libraries using minicell display |
| US20030166099A1 (en) * | 2001-06-05 | 2003-09-04 | Sabbadini Roger A. | Minicells comprising membrane proteins |
-
2002
- 2002-05-28 CA CA002517027A patent/CA2517027A1/en not_active Abandoned
- 2002-05-28 EP EP10008869.9A patent/EP2272946B9/en not_active Revoked
- 2002-05-28 ES ES10008869.9T patent/ES2541351T3/en not_active Expired - Lifetime
- 2002-05-28 AU AU2002318168A patent/AU2002318168B2/en not_active Expired
- 2002-05-28 WO PCT/US2002/016877 patent/WO2003072014A2/en not_active Ceased
- 2002-05-28 EP EP02747872A patent/EP1487965A4/en not_active Withdrawn
- 2002-05-28 EP EP20110000796 patent/EP2390308A1/en not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003033519A2 (en) * | 2001-10-15 | 2003-04-24 | Engeneic Gene Therapy Pty Limited | Intact minicells as vectors for dna transfer and gene therapy in vitro and in vivo |
Non-Patent Citations (3)
| Title |
|---|
| GIACALONE ET AL: "Immune responses elicited by bacterial minicells capable of simultaneous DNA and protein antigen delivery", VACCINE, BUTTERWORTH SCIENTIFIC. GUILDFORD, GB, vol. 24, no. 33-34, 14 August 2006 (2006-08-14), pages 6009 - 6017, XP005571294, ISSN: 0264-410X * |
| KHACHATOURIANS G G: "MINICELLS AS SPECIALIZED VACCINES AND VACCINE CARRIERS", ISAACSON, R. E. (ED.). RECOMBINANT DNA VACCINES: RATIONALE AND STRATEGY. XV+409P. MARCEL DEKKER, INC.: NEW YORK, NEW YORK, USA; BASEL, SWITZERLAND. ILLUS, 1992, pages 323 - 333, XP009072825, ISSN: 0-8247-8699-8 * |
| SUZUKI M ET AL: "PRODUCTION IN ESCHERICHIA-COLI OF BIOLOGICALLY ACTIVE SECRETIN A GASTRO INTESTINAL HORMONE", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 79, no. 8, 1982, pages 2475 - 2479, XP002400466, ISSN: 0027-8424 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003072014B1 (en) | 2004-04-22 |
| ES2541351T3 (en) | 2015-07-17 |
| HK1153229A1 (en) | 2012-03-23 |
| EP2272946B1 (en) | 2015-04-08 |
| EP2390308A1 (en) | 2011-11-30 |
| EP2272946B9 (en) | 2015-06-24 |
| AU2002318168B2 (en) | 2007-12-13 |
| WO2003072014A2 (en) | 2003-09-04 |
| EP2272946A3 (en) | 2011-07-27 |
| WO2003072014A3 (en) | 2004-02-12 |
| AU2002318168A1 (en) | 2003-09-09 |
| EP1487965A2 (en) | 2004-12-22 |
| CA2517027A1 (en) | 2003-09-04 |
| EP2272946A2 (en) | 2011-01-12 |
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