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EP1483367A4 - Bacterie a genome reduit - Google Patents

Bacterie a genome reduit

Info

Publication number
EP1483367A4
EP1483367A4 EP03733830A EP03733830A EP1483367A4 EP 1483367 A4 EP1483367 A4 EP 1483367A4 EP 03733830 A EP03733830 A EP 03733830A EP 03733830 A EP03733830 A EP 03733830A EP 1483367 A4 EP1483367 A4 EP 1483367A4
Authority
EP
European Patent Office
Prior art keywords
genome
bacterium
methods
present
smaller
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP03733830A
Other languages
German (de)
English (en)
Other versions
EP1483367A2 (fr
EP1483367B1 (fr
Inventor
Frederick R Blattner
Gyorgy Posfai
Christopher D Herring
Guy Plunkett
Jeremy D Glasner
Trevor Martin Twose
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Alumni Research Foundation
Original Assignee
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Publication of EP1483367A2 publication Critical patent/EP1483367A2/fr
Publication of EP1483367A4 publication Critical patent/EP1483367A4/fr
Application granted granted Critical
Publication of EP1483367B1 publication Critical patent/EP1483367B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/08—Reducing the nucleic acid content
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185—Escherichia
    • C12R2001/19—Escherichia coli

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP03733830A 2002-01-23 2003-01-22 Bacterie a genome reduit Expired - Lifetime EP1483367B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57582 2002-01-23
US10/057,582 US6989265B2 (en) 2002-01-23 2002-01-23 Bacteria with reduced genome
PCT/US2003/001800 WO2003070880A2 (fr) 2002-01-23 2003-01-22 Bacterie a genome reduit

Publications (3)

Publication Number Publication Date
EP1483367A2 EP1483367A2 (fr) 2004-12-08
EP1483367A4 true EP1483367A4 (fr) 2005-08-31
EP1483367B1 EP1483367B1 (fr) 2010-05-26

Family

ID=22011493

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03733830A Expired - Lifetime EP1483367B1 (fr) 2002-01-23 2003-01-22 Bacterie a genome reduit

Country Status (18)

Country Link
US (2) US6989265B2 (fr)
EP (1) EP1483367B1 (fr)
JP (2) JP4658478B2 (fr)
KR (1) KR100967592B1 (fr)
CN (2) CN1620497B (fr)
AT (1) ATE469230T1 (fr)
AU (2) AU2003239116B8 (fr)
BR (2) BRPI0307125B1 (fr)
CA (1) CA2473922C (fr)
DE (1) DE60332708D1 (fr)
IL (2) IL162911A0 (fr)
IS (1) IS7355A (fr)
MX (1) MX264365B (fr)
NO (1) NO330918B1 (fr)
NZ (1) NZ534010A (fr)
SG (1) SG155052A1 (fr)
WO (1) WO2003070880A2 (fr)
ZA (1) ZA200405509B (fr)

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US6989265B2 (en) * 2002-01-23 2006-01-24 Wisconsin Alumni Research Foundation Bacteria with reduced genome
US20060270043A1 (en) * 2002-01-23 2006-11-30 Blattner Frederick R Bacteria with reduced genome
US8039243B2 (en) * 2002-01-23 2011-10-18 Wisconsin Alumni Research Foundation Insertion sequence-free bacteria
US7303906B2 (en) * 2002-09-06 2007-12-04 Wisconsin Alumni Research Foundation Competent bacteria
CA2558749A1 (fr) * 2004-02-27 2005-09-29 President And Fellows Of Harvard College Synthese de polynucleotides
WO2005087940A1 (fr) * 2004-03-11 2005-09-22 Wisconsin Alumni Research Foundation Micro-organismes genetiquement modifies presentant un metabolisme modifie
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WO2006057341A1 (fr) * 2004-11-26 2006-06-01 Kyowa Hakko Kogyo Co., Ltd. Micro-organisme utile sur le plan industriel
US20070004041A1 (en) * 2005-06-30 2007-01-04 Codon Devices, Inc. Heirarchical assembly methods for genome engineering
US8178339B2 (en) 2005-08-20 2012-05-15 Scarab Genomics Llc Reduced genome E. coli
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DE102006004871A1 (de) * 2006-02-02 2007-08-09 Wacker Chemie Ag Mikroorganismenstamm zur Produktion von rekombinanten Proteinen
EP2027268B1 (fr) * 2006-04-22 2010-07-07 Scarab Genomics, LLC PROCÉDÉS ET COMPOSITIONS PERMETTANT DE PRODUIRE DES PROTÉINES RECOMBINANTES EN UTILISANT UN GÈNE D'ARNt
EP2049668A2 (fr) 2006-08-03 2009-04-22 Wisconsin Alumni Research Foundation Systèmes de vecteurs
US20110165680A1 (en) * 2008-09-12 2011-07-07 Scarab Genomics, Llc Clean genome bactofection
EP2396015B1 (fr) 2009-02-12 2013-04-17 Scarab Genomics LLC Compositions comportant des bactéries de génome réduit pour utilisation dans le traitement de la septicémie
BR112012011990A2 (pt) 2009-11-18 2015-09-29 Myriant Corp microrganismo que não ocorre naturalmente e método para produzir ácido succínico
WO2011080505A2 (fr) 2009-12-28 2011-07-07 Bigdna Ltd Procédé de culture de phage pour un usage commercial
US10224182B2 (en) 2011-10-17 2019-03-05 Novellus Systems, Inc. Mechanical suppression of parasitic plasma in substrate processing chamber
US9340791B2 (en) 2011-10-20 2016-05-17 Scarab Genomics, Llc Reduced genome bacteria with improved genetic stability
EP2825663B1 (fr) 2012-03-13 2019-08-07 Board of Trustees of the University of Arkansas Plateforme d'expression et de purification de protéines à base de séparatome
US9484233B2 (en) 2012-04-13 2016-11-01 Novellus Systems, Inc. Carousel reactor for multi-station, sequential processing systems
HK1213008A1 (zh) 2012-11-06 2016-06-24 艾杜罗生物科技公司 兼性减毒细菌种类及其制备和使用方法
US9449795B2 (en) 2013-02-28 2016-09-20 Novellus Systems, Inc. Ceramic showerhead with embedded RF electrode for capacitively coupled plasma reactor
US11053513B2 (en) 2013-07-15 2021-07-06 Donald Danforth Plant Science Center Enhanced oil production and stress tolerance in plants
US9822371B2 (en) 2013-09-17 2017-11-21 The Board Of Trustees Of The University Of Arkansas E. coli separatome-based protein expression and purification platform
EP3068887B1 (fr) 2013-11-14 2019-10-30 Scarab Genomics LLC Bactéries présentant une meilleure capacité métabolique
AU2015225439B2 (en) * 2014-03-03 2020-12-17 Scarab Genomics, Llc Enhanced production of recombinant CRM197 in E. coli
CA2957921A1 (fr) 2014-07-22 2016-01-28 Nmc, Inc. Systemes ameliores de fixation du carbone chez les plantes et les algues
CN107532123A (zh) 2015-04-02 2018-01-02 斯卡拉布基因组有限责任公司 用于基因组减少的细菌的延长连续流发酵的材料和方法
AU2018329671B2 (en) 2017-09-05 2023-12-07 Scarab Genomics, Llc Methods and compositions for improved expression of recombinant proteins
CN112680393B (zh) * 2021-01-15 2023-04-07 江南大学 一种能提高生产效率的无菌毛大肠杆菌的构建及应用
CN114410564B (zh) * 2022-04-02 2022-07-19 中国农业大学 一种用于5-氨基乙酰丙酸生产的菌株及生产方法

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Also Published As

Publication number Publication date
ZA200405509B (en) 2005-06-29
IS7355A (is) 2004-07-20
WO2003070880A2 (fr) 2003-08-28
EP1483367A2 (fr) 2004-12-08
AU2003239116A1 (en) 2003-09-09
WO2003070880A3 (fr) 2004-09-23
NO330918B1 (no) 2011-08-15
CN103540543B (zh) 2015-07-22
US6989265B2 (en) 2006-01-24
JP2011045371A (ja) 2011-03-10
HK1072273A1 (en) 2005-08-19
ATE469230T1 (de) 2010-06-15
JP2005517429A (ja) 2005-06-16
BRPI0307125B1 (pt) 2019-07-09
IL195374A (en) 2011-04-28
CN1620497A (zh) 2005-05-25
AU2008202865A1 (en) 2008-07-24
BRPI0307125A2 (pt) 2016-11-01
IL162911A0 (en) 2005-11-20
JP4658478B2 (ja) 2011-03-23
AU2003239116B8 (en) 2008-07-10
AU2003239116B2 (en) 2008-04-03
US20070031969A1 (en) 2007-02-08
EP1483367B1 (fr) 2010-05-26
CA2473922C (fr) 2013-09-24
MX264365B (es) 2009-02-06
MXPA04006942A (es) 2004-12-06
KR100967592B1 (ko) 2010-07-05
SG155052A1 (en) 2009-09-30
NZ534010A (en) 2008-03-28
KR20040077766A (ko) 2004-09-06
DE60332708D1 (de) 2010-07-08
NO20043465L (no) 2004-10-22
US20030138937A1 (en) 2003-07-24
US8043842B2 (en) 2011-10-25
CA2473922A1 (fr) 2003-08-28
CN103540543A (zh) 2014-01-29
JP5255030B2 (ja) 2013-08-07
CN1620497B (zh) 2014-11-19

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