EP1478758A4 - Polymorphismes de genes d'elastine, de fibrilline et de genes lies predisposant a une restenose et a une atherosclerose - Google Patents
Polymorphismes de genes d'elastine, de fibrilline et de genes lies predisposant a une restenose et a une atheroscleroseInfo
- Publication number
- EP1478758A4 EP1478758A4 EP03706019A EP03706019A EP1478758A4 EP 1478758 A4 EP1478758 A4 EP 1478758A4 EP 03706019 A EP03706019 A EP 03706019A EP 03706019 A EP03706019 A EP 03706019A EP 1478758 A4 EP1478758 A4 EP 1478758A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- fibrillin
- arose
- elastin
- polymorphisms
- restenosis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 201000001320 Atherosclerosis Diseases 0.000 title 1
- 102000016942 Elastin Human genes 0.000 title 1
- 108010014258 Elastin Proteins 0.000 title 1
- DPUYCSDGMSDKKV-MKBYFEBXSA-N N-Acetyl-L-leucyl-L-isoleucylglycyl-L-valyl-N-methyl-L-prolinamide Chemical compound CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)NC DPUYCSDGMSDKKV-MKBYFEBXSA-N 0.000 title 1
- 229920002549 elastin Polymers 0.000 title 1
- 108060002895 fibrillin Proteins 0.000 title 1
- 102000013370 fibrillin Human genes 0.000 title 1
- 102000054765 polymorphisms of proteins Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 208000037803 restenosis Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Heart & Thoracic Surgery (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Vascular Medicine (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35288502P | 2002-02-01 | 2002-02-01 | |
| US352885P | 2002-02-01 | ||
| PCT/US2003/003001 WO2003064663A1 (fr) | 2002-02-01 | 2003-02-03 | Polymorphismes de genes d'elastine, de fibrilline et de genes lies predisposant a une restenose et a une atherosclerose |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP1478758A1 EP1478758A1 (fr) | 2004-11-24 |
| EP1478758A4 true EP1478758A4 (fr) | 2006-08-30 |
Family
ID=27663146
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP03706019A Withdrawn EP1478758A4 (fr) | 2002-02-01 | 2003-02-03 | Polymorphismes de genes d'elastine, de fibrilline et de genes lies predisposant a une restenose et a une atherosclerose |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP1478758A4 (fr) |
| JP (1) | JP2005531287A (fr) |
| WO (1) | WO2003064663A1 (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU0700024D0 (en) * | 2007-01-11 | 2007-03-28 | Mta Szegedi Biolog Koezpont | Use of enhancers in biglycan activuty in the preparation of pharmaceutical compositions having utility in cardiac diseases |
| PL2588593T3 (pl) * | 2010-06-30 | 2018-01-31 | Avon Prod Inc | Kompozycje i sposoby stymulowania MAGP-1 dla poprawy wyglądu skóry |
| EP4019035A1 (fr) * | 2020-12-23 | 2022-06-29 | Institut National De La Sante Et De La Recherche Medicale - Inserm | Nouveaux fragments recombinants de fibrilline-1 et leurs procédés d'utilisation |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000050068A2 (fr) * | 1999-02-26 | 2000-08-31 | University Of Utah Research Foundation | Compositions a base d'elastine |
-
2003
- 2003-02-03 WO PCT/US2003/003001 patent/WO2003064663A1/fr not_active Ceased
- 2003-02-03 EP EP03706019A patent/EP1478758A4/fr not_active Withdrawn
- 2003-02-03 JP JP2003564254A patent/JP2005531287A/ja active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000050068A2 (fr) * | 1999-02-26 | 2000-08-31 | University Of Utah Research Foundation | Compositions a base d'elastine |
Non-Patent Citations (4)
| Title |
|---|
| LI DEAN Y ET AL: "Elastin is an essential determinant of arterial morphogenesis", NATURE, NATURE PUBLISHING GROUP, LONDON, US, vol. 393, no. 6682, 21 May 1998 (1998-05-21), pages 276 - 280, XP002148309, ISSN: 0028-0836 * |
| PANETTA C ET AL: "Identification of fibrillins as a major component of coronary atherosclerotic plaques", CARDIOVASCULAR PATHOLOGY 1998 UNITED STATES, vol. 7, no. 2, 1998, pages 69 - 74, XP002389645, ISSN: 1054-8807 * |
| See also references of WO03064663A1 * |
| WU K-J ET AL: "CHARACTERIZATION OF DIFFERENTIAL GENE EXPRESSION IN MONKEY ARTERIAL NEOINTIMA FOLLOWING BALLOON CATHETER INJURY", INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, SPANDIDOS, ATHENS, GR, vol. 6, no. 4, October 2000 (2000-10-01), pages 433 - 440, XP008010068, ISSN: 1107-3756 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1478758A1 (fr) | 2004-11-24 |
| WO2003064663A1 (fr) | 2003-08-07 |
| JP2005531287A (ja) | 2005-10-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 20040831 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR |
|
| AX | Request for extension of the european patent |
Extension state: AL LT LV MK RO |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12Q 1/68 20060101ALI20060712BHEP Ipc: C12N 15/00 20060101ALI20060712BHEP Ipc: C12N 15/85 20060101AFI20030813BHEP |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20060727 |
|
| 17Q | First examination report despatched |
Effective date: 20061026 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
| 18D | Application deemed to be withdrawn |
Effective date: 20070508 |