EP1454647A3 - Dispositif d'inhalation - Google Patents

Dispositif d'inhalation Download PDF

Info

Publication number: EP1454647A3
Authority: EP; European Patent Office
Prior art keywords: powder; flow path; inhalation; stream; air
Prior art date: 1997-03-14
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

EP04008146A

Other languages

German (de)

English (en)

Other versions

EP1454647B1 (fr

EP1454647A2 (fr

Inventor

Jan Andersson

John Conway

Allan Dagsland

Stefan Friess

Harald Heckenmüller

Uwe Rollwage

Hans Strid

Volker Tiedemann

Jan Trofast

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

AstraZeneca AB

Original Assignee

AstraZeneca AB

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-03-14

Filing date

1998-03-13

Publication date

2004-11-17

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26662934&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP1454647(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1997-03-14 Priority claimed from SE9700937A external-priority patent/SE9700937D0/xx

1997-10-21 Priority claimed from SE9703829A external-priority patent/SE9703829D0/xx

1998-03-13 Application filed by AstraZeneca AB filed Critical AstraZeneca AB

2004-09-08 Publication of EP1454647A2 publication Critical patent/EP1454647A2/fr

2004-11-17 Publication of EP1454647A3 publication Critical patent/EP1454647A3/fr

2006-01-25 Application granted granted Critical

2006-01-25 Publication of EP1454647B1 publication Critical patent/EP1454647B1/fr

2018-03-13 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/001—Particle size control
- A61M11/002—Particle size control by flow deviation causing inertial separation of transported particles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
- A61M15/0006—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
- A61M15/0008—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means rotating by airflow
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/007—Mechanical counters
- A61M15/0071—Mechanical counters having a display or indicator
- A61M15/0076—Mechanical counters having a display or indicator on a drum
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0086—Inhalation chambers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/14—Static flow deviators in tubes disturbing laminar flow in tubes, e.g. archimedes screws
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Anesthesiology (AREA)
Biomedical Technology (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Animal Behavior & Ethology (AREA)
Pulmonology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biophysics (AREA)
Medicinal Preparation (AREA)
Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
Medical Preparation Storing Or Oral Administration Devices (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nozzles (AREA)
External Artificial Organs (AREA)
Manipulator (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

EP04008146A 1997-03-14 1998-03-13 Dispositif d'inhalation Expired - Lifetime EP1454647B1 (fr)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
SE9700937A SE9700937D0 (sv)	1997-03-14	1997-03-14	Powder inhaler I
SE9700937		1997-03-14
SE9703829A SE9703829D0 (sv)	1997-10-21	1997-10-21	Powder inhaleri
SE9703829		1997-10-21
EP98909946A EP1017438B1 (fr)	1997-03-14	1998-03-13	Dispositif d'inhalation

Related Parent Applications (1)

Application Number	Title	Priority Date	Filing Date
EP98909946A Division EP1017438B1 (fr)	1997-03-14	1998-03-13	Dispositif d'inhalation

Publications (3)

Publication Number	Publication Date
EP1454647A2 EP1454647A2 (fr)	2004-09-08
EP1454647A3 true EP1454647A3 (fr)	2004-11-17
EP1454647B1 EP1454647B1 (fr)	2006-01-25

Family

ID=26662934

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
EP98909946A Expired - Lifetime EP1017438B1 (fr)	1997-03-14	1998-03-13	Dispositif d'inhalation
EP04008146A Expired - Lifetime EP1454647B1 (fr)	1997-03-14	1998-03-13	Dispositif d'inhalation

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
EP98909946A Expired - Lifetime EP1017438B1 (fr)	1997-03-14	1998-03-13	Dispositif d'inhalation

Country Status (32)

Country	Link
US (4)	US6655380B1 (fr)
EP (2)	EP1017438B1 (fr)
JP (1)	JP4138019B2 (fr)
KR (1)	KR100492839B1 (fr)
CN (1)	CN1247275C (fr)
AR (1)	AR008957A1 (fr)
AT (2)	ATE316398T1 (fr)
AU (1)	AU741505B2 (fr)
BR (1)	BR9811456A (fr)
CA (1)	CA2283258C (fr)
CZ (1)	CZ298388B6 (fr)
DE (2)	DE69833286T2 (fr)
DK (1)	DK1454647T3 (fr)
EE (2)	EE04420B1 (fr)
ES (2)	ES2256807T3 (fr)
HU (1)	HU223792B1 (fr)
ID (1)	ID23498A (fr)
IL (2)	IL165400A0 (fr)
IS (1)	IS2780B (fr)
MY (1)	MY124177A (fr)
NO (1)	NO321728B1 (fr)
NZ (3)	NZ513357A (fr)
PL (2)	PL188765B1 (fr)
PT (2)	PT1454647E (fr)
RU (1)	RU2201768C2 (fr)
SA (1)	SA98190222B1 (fr)
SI (1)	SI1017438T1 (fr)
SK (1)	SK285517B6 (fr)
TR (2)	TR200001837T2 (fr)
TW (1)	TW469832U (fr)
UA (2)	UA89608C2 (fr)
WO (1)	WO1998041256A2 (fr)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH0858940A (ja) *	1994-08-25	1996-03-05	Mukai Kogyo Kk	コンベア装置
US7131441B1 (en)	1995-12-07	2006-11-07	Skyepharma Ag	Inhaler for multiple dosed administration of a pharmacological dry powder
DE59605366D1 (de)	1995-12-07	2000-07-06	Jago Pharma Ag Muttenz	Inhalator zur mehrfachen dosisweisen abgabe eines pharmakologischen trockenpulvers
TW469832U (en)	1997-03-14	2001-12-21	Astra Ab	Inhalation device
US9006175B2 (en)	1999-06-29	2015-04-14	Mannkind Corporation	Potentiation of glucose elimination
SE0000935D0 (sv) *	2000-03-21	2000-03-21	Astrazeneca Ab	An inhalation device
EP1163920B1 (fr) *	2000-06-13	2004-09-01	Andi-Ventis Limited	Pièce buccale pour inhalateur de poudres
WO2002036163A2 (fr) *	2000-10-31	2002-05-10	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Nouvelles compositions de medicaments
US7776315B2 (en)	2000-10-31	2010-08-17	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Pharmaceutical compositions based on anticholinergics and additional active ingredients
SE0101825D0 (sv)	2001-05-22	2001-05-22	Astrazeneca Ab	An Inhalation device
JP4795637B2 (ja)	2001-09-28	2011-10-19	カーブテクノロジー，インコーポレイティド	鼻ネブライザー
SI1494732T1 (sl)	2002-03-20	2008-08-31	Mannking Corp	Inhalacijski aparat
US8122881B2 (en)	2002-05-09	2012-02-28	Kurve Technology, Inc.	Particle dispersion device for nasal delivery
DK1539286T3 (en) *	2002-09-16	2015-04-27	Sanofi Sa	INHALATOR FOR POWDER-DEFINED NAME MEDICAL SUBSTANCES
PL1725285T3 (pl)	2004-03-10	2020-03-31	Glaxo Group Limited	Urządzenie dozujące z członem ograniczającym
BRPI0508282B1 (pt) *	2004-03-19	2015-08-18	Unilever Nv	Sistema e dispositivo de purificação de água alimentado por gravidade.
KR101273120B1 (ko)	2004-08-20	2013-06-13	맨카인드 코포레이션	다이케토피페라진 합성의 촉매 작용
BR122019022692B1 (pt)	2004-08-23	2023-01-10	Mannkind Corporation	Composição terapêutica em pó seco contendo dicetopiperazina, pelo menos um tipo de cátion e um agente biologicamente ativo
WO2007011743A2 (fr)	2005-07-14	2007-01-25	Lipothera, Inc.	Preparation lipolytique amelioree a liberation prolongee pour traitement de tissu adipeux localise
KR101486829B1 (ko)	2005-09-14	2015-01-29	맨카인드 코포레이션	결정질 미립자 표면에 대한 활성제의 친화력의 증가를 기반으로 하는 약물 제제의 방법
EP1965848A4 (fr) *	2005-12-23	2012-12-05	Astrazeneca Ab	Nouveau dispositif
FR2896419B1 (fr) *	2006-01-25	2009-02-27	Valois Sas	Embout buccal pour dispositif de distribution de produit fluide
US20070181119A1 (en) *	2006-02-08	2007-08-09	Weinstein Robert E	Inhaler Device
EP1986679B1 (fr)	2006-02-22	2017-10-25	MannKind Corporation	Procédé pour améliorer les propriétés pharmaceutiques de microparticules comprenant de la dicétopipérazine et un agent actif
US8127763B2 (en) *	2006-03-03	2012-03-06	Stc.Unm	Dry powder inhaler with aeroelastic dispersion mechanism
JP5188991B2 (ja) *	2006-03-03	2013-04-24	エスティーシー．ユーエヌエム	空力弾性分配メカニズムを有するドライパウダー吸入器
JP4948534B2 (ja) *	2006-06-27	2012-06-06	大塚製薬株式会社	粉末吸入器
AU315527S (en)	2006-09-28	2007-08-03	Glaxo Group Ltd	Inhalation device
US20100139655A1 (en) *	2006-11-19	2010-06-10	Aespironics Ltd	Dry-powder inhaler
JP5570996B2 (ja)	2007-12-14	2014-08-13	エアロデザインズインコーポレイテッド	エアロゾル化可能な食料品の送達
TWI677355B (zh)	2008-06-13	2019-11-21	美商曼凱公司	用於藥物傳輸之乾粉吸入器及系統
US8485180B2 (en)	2008-06-13	2013-07-16	Mannkind Corporation	Dry powder drug delivery system
ES2421385T3 (es)	2008-06-20	2013-09-02	Mannkind Corp	Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación
TWI614024B (zh)	2008-08-11	2018-02-11	曼凱公司	超快起作用胰島素之用途
US8314106B2 (en)	2008-12-29	2012-11-20	Mannkind Corporation	Substituted diketopiperazine analogs for use as drug delivery agents
EP2676695A3 (fr)	2009-03-11	2017-03-01	MannKind Corporation	Appareil, système et procédé de mesure de résistance d'un inhalateur
US9132084B2 (en)	2009-05-27	2015-09-15	Neothetics, Inc.	Methods for administration and formulations for the treatment of regional adipose tissue
MY186975A (en)	2009-06-12	2021-08-26	Mannkind Corp	Diketopiperazine microparticles with defined specific surface areas
CA2764469C (fr) *	2009-06-25	2017-10-03	Boehringer Ingelheim Vetmedica Gmbh	Inhalateur
US9016147B2 (en)	2009-11-03	2015-04-28	Mannkind Corporation	Apparatus and method for simulating inhalation efforts
CA2779488A1 (fr)	2009-11-12	2011-05-19	Stc.Unm	Inhalateur pour poudre seche avec un element de dispersion par flottement
MX359281B (es)	2010-06-21	2018-09-21	Mannkind Corp	Sistema y metodos para suministrar un farmaco en polvo seco.
EP2646012A4 (fr)	2010-11-24	2014-12-10	Neothetics Inc	Formulations monothérapeutiques d'agonistes bêta sélectifs, lipophiles et à action prolongée, et procédés de traitement cosmétique de l'adiposité et du renflement de la silhouette
WO2012078804A1 (fr)	2010-12-07	2012-06-14	Respira Therapeutics, Inc.	Inhalateur de poudre sèche
US8925726B2 (en)	2011-04-01	2015-01-06	Mannkind Corporation	Blister package for pharmaceutical cartridges
US9750901B2 (en) *	2011-06-13	2017-09-05	Shanghai Xiuxin Chenpon Pharmaceutical Technology Co., Ltd.	Dry powder drug-dosing device
WO2012174472A1 (fr)	2011-06-17	2012-12-20	Mannkind Corporation	Microparticules de dicétopipérazine de capacité élevée
CA2852536A1 (fr)	2011-10-24	2013-05-02	Mannkind Corporation	Procedes et compositions pour traiter la douleur
US10463815B2 (en)	2012-02-21	2019-11-05	Respira Therapeutics, Inc.	Inhaler to deliver substances for prophylaxis or prevention of disease or injury caused by the inhalation of biological or chemical agents
CA2878457C (fr)	2012-07-12	2021-01-19	Mannkind Corporation	Systemes et procedes de liberation de medicament en poudre seche
EP2911690A1 (fr)	2012-10-26	2015-09-02	MannKind Corporation	Compositions et procédés de vaccin antigrippal inhalable
EP2970149B1 (fr)	2013-03-15	2019-08-21	MannKind Corporation	Compositions de dicétopipérazine microcristallines et procédés
EP3021834A1 (fr)	2013-07-18	2016-05-25	MannKind Corporation	Compositions pharmaceutiques en poudre sèche stables à la chaleur et procédés
CN105517607A (zh)	2013-08-05	2016-04-20	曼金德公司	吹入设备和方法
WO2015024652A1 (fr)	2013-08-20	2015-02-26	Boehringer Ingelheim Vetmedica Gmbh	Inhalateur
SI3035885T1 (sl)	2013-08-20	2020-04-30	Boehringer Ingelheim Vetmedica Gmbh	Inhalator
CA2913817C (fr)	2013-08-20	2022-07-05	Boehringer Ingelheim Vetmedica Gmbh	Inhalateur
US10307464B2 (en)	2014-03-28	2019-06-04	Mannkind Corporation	Use of ultrarapid acting insulin
US10561806B2 (en)	2014-10-02	2020-02-18	Mannkind Corporation	Mouthpiece cover for an inhaler
CA2972826C (fr)	2015-01-14	2023-09-12	Respira Therapeutics, Inc.	Procedes et dispositifs de dispersion de poudre
US20160256641A1 (en) *	2015-03-02	2016-09-08	Edward Lisberg	Delivery System for Metered Dose Inhalers
US11116918B2 (en)	2015-03-02	2021-09-14	Abithas, Inc.	Delivery system for metered dose inhalers
CN205322939U (zh) *	2015-10-27	2016-06-22	深圳市杰仕博科技有限公司	隔热吸嘴
US10512921B2 (en) *	2016-05-09	2019-12-24	Funai Electric Co., Ltd.	Maintenance apparatus for vaporizing device
JP7209715B2 (ja) *	2017-11-23	2023-01-20	チアタイティエンチンファーマシューティカルグループカンパニーリミテッド	新型乾燥粉末吸入装置
US11925749B2 (en) *	2021-03-18	2024-03-12	Funai Electric Co., Ltd.	Venting of pharmaceutical drug delivery device for air flow and humidity control
CN114209494B (zh) *	2021-12-02	2023-11-10	江西省儿童医院	一种眼科使用的红眼病治疗用雾化治疗器

Citations (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2470297A (en) *	1947-09-04	1949-05-17	Abbott Lab	Inhalator
GB2179260A (en) *	1985-08-01	1987-03-04	Hurka Wilhelm	Inhaler
US4811731A (en) *	1985-07-30	1989-03-14	Glaxo Group Limited	Devices for administering medicaments to patients
EP0424790A2 (fr) *	1989-10-27	1991-05-02	Miat S.P.A.	Inhalateur à dosages multiples pour des médicamments sous forme de poudre
WO1994008552A2 (fr) *	1992-10-19	1994-04-28	Dura Pharmaceuticals, Inc.	Inhalateur pour poudre seche
WO1994014492A2 (fr) *	1992-12-18	1994-07-07	Schering Corporation	Inhalateur pour medicaments en poudre
DE4415462C1 (de) *	1994-05-03	1995-08-31	Transcoject Marketing Gmbh	Inhalator
EP0705614A1 (fr) *	1989-04-28	1996-04-10	Riker Laboratories, Inc.	Dispositif d'inhalation de poudre sèche

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE25422C (de) *			J. HASSLER in Baden - Soden, Reg.-Bez. Wiesbaden	Apparat zum Zerstäuben pulverförmiger Stoffe für Inhalationszwecke
US2470296A (en)	1948-04-30	1949-05-17	Abbott Lab	Inhalator
US2573918A (en)	1949-11-05	1951-11-06	Vick Chemical Company	Device for dispensing medicaments
GB1295081A (en)	1969-01-08	1972-11-01	Fisons Pharmaceuticals Ltd	A method and device for dispensing particulate medicament material from a container
GB1118341A (en) *	1965-04-20	1968-07-03	Fisons Pharmaceuticals Ltd	Inhalation device
GB1459426A (en)	1973-02-26	1976-12-22	Allen & Hanburys Ltd	Inhalation devices
US3948264A (en)	1975-05-21	1976-04-06	Mead Johnson & Company	Inhalation device
SE411705B (sv)	1976-11-09	1980-02-04	Draco Ab	Anordning for generering av en avskermad, vesentligen drivmedelsfri aerosol
JPS608907B2 (ja)	1978-12-19	1985-03-06	新日本製鐵株式会社	狭開先潜弧溶接法
SE438261B (sv) *	1981-07-08	1985-04-15	Draco Ab	Anvendning i dosinhalator av ett perforerat membran
DE3274065D1 (de)	1981-07-08	1986-12-11	Draco Ab	Powder inhalator
US4805811A (en) *	1985-03-29	1989-02-21	Aktiebolaget Draco	Dosage device
SE453566B (sv)	1986-03-07	1988-02-15	Draco Ab	Anordning vid pulverinhalatorer
US4739754A (en)	1986-05-06	1988-04-26	Shaner William T	Suction resistant inhalator
SE466684B (sv) *	1989-03-07	1992-03-23	Draco Ab	Anordning vid en inhalator samt foerfarande foer att med anordningen registrera medicinering med inhalator
US5176132A (en) *	1989-05-31	1993-01-05	Fisons Plc	Medicament inhalation device and formulation
US5201308A (en) *	1990-02-14	1993-04-13	Newhouse Michael T	Powder inhaler
US5113855A (en) *	1990-02-14	1992-05-19	Newhouse Michael T	Powder inhaler
NZ238489A (en)	1990-06-14	1995-09-26	Rhone Poulenc Rorer Ltd	Inhaler with capsule in swirling chamber: capsule pierced in chamber
GB9015522D0 (en)	1990-07-13	1990-08-29	Braithwaite Philip W	Inhaler
DE4027391A1 (de)	1990-08-30	1992-03-12	Boehringer Ingelheim Kg	Treibgasfreies inhalationsgeraet
EP0548152B1 (fr)	1990-09-12	1996-07-24	BISGAARD, Hans	Dispositif d'inhalation
WO1992004928A2 (fr)	1990-09-26	1992-04-02	Pharbita B.V.	Dispositif d'inhalation pourvu d'un reservoir pour plusieurs doses de produit d'inhalation, dispositif de transport, chambre de turbulence
US5429122A (en) *	1990-09-26	1995-07-04	Zanen; Pieter	Inhaler devices provided with a reservoir for several doses of medium for inhaling, transporting device, whirl chamber
US5243970A (en) *	1991-04-15	1993-09-14	Schering Corporation	Dosing device for administering metered amounts of powdered medicaments to patients
NZ243314A (en)	1991-06-26	1994-07-26	Schering Corp	Powder dispenser; single metered dose rotated to dispensing conduit
US5203323A (en) *	1991-07-02	1993-04-20	Tritle Paul E	Metered dose inhaler spacer device and associated cleaning brush
IL107534A0 (en)	1992-11-12	1994-02-27	Minnesota Mining & Mfg	Powder dispenser
AT398277B (de)	1992-12-11	1994-11-25	Hurka Wilhelm	Inhalationsgerät
DE69413528T2 (de)	1993-04-06	1999-05-06	Minnesota Mining And Mfg. Co., Saint Paul, Minn.	Vorrichtung zum deagglomerieren für trockenpulverinhalatoren
US5372128A (en) *	1993-04-14	1994-12-13	Habley Medical Technology Corporation	Fluidizing powder inhaler
SE9302550D0 (sv) *	1993-07-30	1993-07-30	Ernst Hoerlin	Powder inhaler
AU1752795A (en)	1994-03-10	1995-09-25	Franco Del Bon	Inhalator
US6102036A (en) *	1994-04-12	2000-08-15	Smoke-Stop	Breath activated inhaler
GB9419269D0 (en)	1994-09-23	1994-11-09	Unilever Plc	Aerosol
SE9404439D0 (sv) *	1994-12-21	1994-12-21	Astra Ab	Inhalation device
FR2738152B1 (fr) *	1995-09-04	1998-01-23	Tebro	Dispositif de pre-dosage de produit pulverulent pour un distributeur de produit
ES2172763T3 (es) *	1996-02-21	2002-10-01	Schering Corp	Inhalador de medicamento en polvo.
TW469832U (en)	1997-03-14	2001-12-21	Astra Ab	Inhalation device
SE9700937D0 (sv) *	1997-03-14	1997-03-14	Astra Ab	Powder inhaler I
SE9700948D0 (sv) *	1997-03-14	1997-03-14	Astra Ab	Powder inhaler X
SE9801114D0 (sv) *	1998-03-30	1998-03-30	Astra Ab	Inhalation device

1998
- 1998-03-02 TW TW090206705U patent/TW469832U/zh not_active IP Right Cessation
- 1998-03-13 WO PCT/SE1998/000457 patent/WO1998041256A2/fr not_active Ceased
- 1998-03-13 RU RU99121399/14A patent/RU2201768C2/ru active
- 1998-03-13 HU HU0000840A patent/HU223792B1/hu not_active IP Right Cessation
- 1998-03-13 SI SI9830700T patent/SI1017438T1/xx unknown
- 1998-03-13 KR KR10-1999-7008296A patent/KR100492839B1/ko not_active Expired - Lifetime
- 1998-03-13 TR TR2000/01837T patent/TR200001837T2/xx unknown
- 1998-03-13 PT PT04008146T patent/PT1454647E/pt unknown
- 1998-03-13 IL IL16540098A patent/IL165400A0/xx not_active IP Right Cessation
- 1998-03-13 CA CA002283258A patent/CA2283258C/fr not_active Expired - Lifetime
- 1998-03-13 EE EEP199900403A patent/EE04420B1/xx unknown
- 1998-03-13 UA UA20040604989A patent/UA89608C2/uk unknown
- 1998-03-13 AT AT04008146T patent/ATE316398T1/de active
- 1998-03-13 PL PL98335799A patent/PL188765B1/pl unknown
- 1998-03-13 IL IL13154798A patent/IL131547A0/xx not_active IP Right Cessation
- 1998-03-13 EE EEP200400122A patent/EE04707B1/xx unknown
- 1998-03-13 AU AU64303/98A patent/AU741505B2/en not_active Expired
- 1998-03-13 UA UA99095001A patent/UA68344C2/uk unknown
- 1998-03-13 DK DK04008146T patent/DK1454647T3/da active
- 1998-03-13 TR TR1999/02240T patent/TR199902240T2/xx unknown
- 1998-03-13 CZ CZ0324299A patent/CZ298388B6/cs not_active IP Right Cessation
- 1998-03-13 ID IDW990988A patent/ID23498A/id unknown
- 1998-03-13 NZ NZ513357A patent/NZ513357A/xx not_active IP Right Cessation
- 1998-03-13 CN CNB988050803A patent/CN1247275C/zh not_active Expired - Lifetime
- 1998-03-13 NZ NZ523896A patent/NZ523896A/en not_active IP Right Cessation
- 1998-03-13 EP EP98909946A patent/EP1017438B1/fr not_active Expired - Lifetime
- 1998-03-13 ES ES04008146T patent/ES2256807T3/es not_active Expired - Lifetime
- 1998-03-13 EP EP04008146A patent/EP1454647B1/fr not_active Expired - Lifetime
- 1998-03-13 JP JP54042398A patent/JP4138019B2/ja not_active Expired - Lifetime
- 1998-03-13 ES ES98909946T patent/ES2227812T3/es not_active Expired - Lifetime
- 1998-03-13 DE DE69833286T patent/DE69833286T2/de not_active Expired - Lifetime
- 1998-03-13 MY MYPI98001119A patent/MY124177A/en unknown
- 1998-03-13 AT AT98909946T patent/ATE275998T1/de active
- 1998-03-13 BR BR9811456-5A patent/BR9811456A/pt not_active IP Right Cessation
- 1998-03-13 PT PT98909946T patent/PT1017438E/pt unknown
- 1998-03-13 NZ NZ337478A patent/NZ337478A/en not_active IP Right Cessation
- 1998-03-13 DE DE69826299T patent/DE69826299T2/de not_active Expired - Lifetime
- 1998-03-13 SK SK1234-99A patent/SK285517B6/sk not_active IP Right Cessation
- 1998-03-13 PL PL98369035A patent/PL190261B1/pl unknown
- 1998-03-13 US US09/066,319 patent/US6655380B1/en not_active Expired - Lifetime
- 1998-03-13 AR ARP980101157A patent/AR008957A1/es active IP Right Grant
- 1998-06-29 SA SA98190222A patent/SA98190222B1/ar unknown
1999
- 1999-09-13 NO NO19994432A patent/NO321728B1/no not_active IP Right Cessation
- 1999-09-13 IS IS5178A patent/IS2780B/is unknown
2003
- 2003-09-29 US US10/673,689 patent/US7841340B2/en not_active Expired - Fee Related
2005
- 2005-05-09 US US11/125,615 patent/US7228860B2/en not_active Expired - Fee Related
2007
- 2007-11-15 US US11/940,346 patent/US7779836B2/en not_active Expired - Fee Related

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2470297A (en) *	1947-09-04	1949-05-17	Abbott Lab	Inhalator
US4811731A (en) *	1985-07-30	1989-03-14	Glaxo Group Limited	Devices for administering medicaments to patients
GB2179260A (en) *	1985-08-01	1987-03-04	Hurka Wilhelm	Inhaler
EP0705614A1 (fr) *	1989-04-28	1996-04-10	Riker Laboratories, Inc.	Dispositif d'inhalation de poudre sèche
EP0424790A2 (fr) *	1989-10-27	1991-05-02	Miat S.P.A.	Inhalateur à dosages multiples pour des médicamments sous forme de poudre
WO1994008552A2 (fr) *	1992-10-19	1994-04-28	Dura Pharmaceuticals, Inc.	Inhalateur pour poudre seche
WO1994014492A2 (fr) *	1992-12-18	1994-07-07	Schering Corporation	Inhalateur pour medicaments en poudre
DE4415462C1 (de) *	1994-05-03	1995-08-31	Transcoject Marketing Gmbh	Inhalator

Also Published As

Publication number	Publication date
EE04707B1 (et)	2006-10-16
DE69826299D1 (de)	2004-10-21
NO994432D0 (no)	1999-09-13
PL335799A1 (en)	2000-05-22
SK285517B6 (sk)	2007-03-01
SK123499A3 (en)	2000-05-16
US7228860B2 (en)	2007-06-12
DK1454647T3 (da)	2006-05-08
UA68344C2 (uk)	2004-08-16
EE200400122A (et)	2005-02-15
ATE275998T1 (de)	2004-10-15
CZ324299A3 (cs)	2000-03-15
EP1454647B1 (fr)	2006-01-25
EP1017438A2 (fr)	2000-07-12
HUP0000840A3 (en)	2000-09-28
PT1017438E (pt)	2004-12-31
CZ298388B6 (cs)	2007-09-19
CN1255867A (zh)	2000-06-07
IL165400A0 (en)	2006-01-15
EP1454647A2 (fr)	2004-09-08
US20080092886A1 (en)	2008-04-24
AR008957A1 (es)	2000-02-23
NZ337478A (en)	2001-09-28
AU6430398A (en)	1998-10-12
NO321728B1 (no)	2006-06-26
KR100492839B1 (ko)	2005-06-07
US6655380B1 (en)	2003-12-02
PL188765B1 (pl)	2005-04-29
KR20000076202A (ko)	2000-12-26
EE04420B1 (et)	2005-02-15
TR199902240T2 (xx)	1999-12-21
UA89608C2 (uk)	2010-02-25
RU2201768C2 (ru)	2003-04-10
SA98190222B1 (ar)	2006-06-10
AU741505B2 (en)	2001-12-06
MY124177A (en)	2006-06-30
DE69833286D1 (de)	2006-04-13
EP1017438B1 (fr)	2004-09-15
PL190261B1 (pl)	2005-11-30
WO1998041256A3 (fr)	1999-02-11
ES2256807T3 (es)	2006-07-16
DE69826299T2 (de)	2005-08-18
IS2780B (is)	2012-05-15
JP2001517980A (ja)	2001-10-09
CA2283258C (fr)	2007-07-17
US7779836B2 (en)	2010-08-24
SI1017438T1 (en)	2005-02-28
NO994432L (no)	1999-11-03
DE69833286T2 (de)	2006-11-02
PT1454647E (pt)	2006-05-31
NZ513357A (en)	2003-03-28
US7841340B2 (en)	2010-11-30
BR9811456A (pt)	2000-09-19
ES2227812T3 (es)	2005-04-01
TW469832U (en)	2001-12-21
CA2283258A1 (fr)	1998-09-24
EE9900403A (et)	2000-04-17
NZ523896A (en)	2004-08-27
ID23498A (id)	2000-04-27
US20040065325A1 (en)	2004-04-08
HU223792B1 (hu)	2005-01-28
HUP0000840A2 (hu)	2000-08-28
WO1998041256A2 (fr)	1998-09-24
JP4138019B2 (ja)	2008-08-20
IL131547A0 (en)	2001-01-28
US20050194008A1 (en)	2005-09-08
ATE316398T1 (de)	2006-02-15
TR200001837T2 (tr)	2001-10-22
IS5178A (is)	1999-09-13
CN1247275C (zh)	2006-03-29

Publication	Publication Date	Title
EP1454647A3 (fr)	2004-11-17	Dispositif d'inhalation
CA2283199A1 (fr)	1998-09-24	Dispositif d'inhalation
EP0839544A3 (fr)	1998-11-25	Inhalateurs
NZ334047A (en)	2000-09-29	Device comprising a reservoir which achieves a tumbling effect on rotation at the inflow path leading to a metering chamber
YU68594A (sh)	1996-10-18	Naprava za inhaliranje
KR0179378B1 (en)	1999-04-01	Powder inhaler
MXPA03010668A (es)	2004-03-02	Dispositivo e inhalacion.
CA2392466A1 (fr)	1997-06-12	Inhalateur pour administrer de multiple doses d'une poudre seche pharmacologique
HUP9901575A2 (hu)	1999-08-30	Eljárás száraz por inhalálására
EP1208863A3 (fr)	2004-01-21	Inhalateur
SE9700940D0 (sv)	1997-03-14	Powder inhaler IV
DE69931265D1 (de)	2006-06-14	Inhalator
TW200607538A (en)	2006-03-01	Medicament inhaler device
PL343319A1 (en)	2001-08-13	Inhalation device
NZ503874A (en)	2002-10-25	Inhaler spacer chamber for powdered medicaments
DK0774986T3 (da)	2000-06-05	Inhalator med optimeringskammer
MX9704489A (es)	1997-10-31	Dispositivo de inhalacion, metodo para dispersar una sustancia farmaceuticamente activa y metodo para administrar una dosis de una sustancia farmaceuticamente activa.

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