EP1451308A4 - Utilisation therapeutique de composes aziridino - Google Patents

Utilisation therapeutique de composes aziridino

Info

Publication number: EP1451308A4
Authority: EP; European Patent Office
Prior art keywords: therapeutic use; aziridino compounds; aziridino; compounds; therapeutic
Prior art date: 2001-11-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP02806003A

Other languages

German (de)

English (en)

Other versions

EP1451308A2 (fr

Inventor

John Chapman

Bernadette Alford

Andrei A Purmal

Boris Zavizion

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

VI Technologies Inc

Original Assignee

VI Technologies Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-11-06

Filing date

2002-11-05

Publication date

2004-11-17

2001-11-06 Priority claimed from PCT/US2001/049956 external-priority patent/WO2002055095A2/fr

2002-11-05 Application filed by VI Technologies Inc filed Critical VI Technologies Inc

2004-09-01 Publication of EP1451308A2 publication Critical patent/EP1451308A2/fr

2004-11-17 Publication of EP1451308A4 publication Critical patent/EP1451308A4/fr

Status Withdrawn legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/396—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having three-membered rings, e.g. aziridine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Diabetes (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Hematology (AREA)
Physical Education & Sports Medicine (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Orthopedic Medicine & Surgery (AREA)
Epidemiology (AREA)
Dermatology (AREA)
Rheumatology (AREA)
Neurosurgery (AREA)
Pulmonology (AREA)
Obesity (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Virology (AREA)
Tropical Medicine & Parasitology (AREA)
Transplantation (AREA)
Hospice & Palliative Care (AREA)
Endocrinology (AREA)
Gastroenterology & Hepatology (AREA)
Emergency Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

EP02806003A 2001-11-06 2002-11-05 Utilisation therapeutique de composes aziridino Withdrawn EP1451308A4 (fr)

Applications Claiming Priority (7)

Application Number	Priority Date	Filing Date	Title
WOPCT/US01/49956		2001-11-06
PCT/US2001/049956 WO2002055095A2 (fr)	2000-11-06	2001-11-06	Procedes et reactifs pour therapie immunomodulatrice extracorporelle
US36564802P	2002-03-18	2002-03-18
US365648P		2002-03-18
US37918802P	2002-05-09	2002-05-09
US379188P		2002-05-09
PCT/US2002/035501 WO2003066806A2 (fr)	2001-11-06	2002-11-05	Utilisation therapeutique de composes aziridino

Publications (2)

Publication Number	Publication Date
EP1451308A2 EP1451308A2 (fr)	2004-09-01
EP1451308A4 true EP1451308A4 (fr)	2004-11-17

Family

ID=27738963

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP02806003A Withdrawn EP1451308A4 (fr)	2001-11-06	2002-11-05	Utilisation therapeutique de composes aziridino

Country Status (5)

Country	Link
EP (1)	EP1451308A4 (fr)
JP (1)	JP2005517023A (fr)
AU (1)	AU2002366446A1 (fr)
CA (1)	CA2466251A1 (fr)
WO (1)	WO2003066806A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20040053208A1 (en) *	1995-08-29	2004-03-18	V. I. TECHNOLOGIES, Inc.	Methods to selectively inactivate parasites in biological compositions
WO2009149081A1 (fr)	2008-06-02	2009-12-10	Novelmed Therapeutics, Inc.	Procédé pour traiter les pathologies inflammatoires

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0419890A2 (fr) *	1989-09-29	1991-04-03	American Cyanamid Company	Formulations pharmaceutiques stables pour des composés antinéoplastiques avec plus d'un groupement éthylèneimine et procédé
WO1997007674A1 (fr) *	1995-08-29	1997-03-06	Pentose Pharmaceuticals, Inc.	Procedes et compositions de modification selective d'acides nucleiques
WO2002055095A2 (fr) *	2000-11-06	2002-07-18	Vi Technologies Inc	Procedes et reactifs pour therapie immunomodulatrice extracorporelle

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6136586A (en) *	1995-08-29	2000-10-24	Vi Technologies, Inc.	Methods for the selective modification of viral nucleic acids
US6093564A (en) *	1997-10-03	2000-07-25	V.I. Technologies, Inc.	Methods and compositions for the selective modification of nucleic acids

2002
- 2002-11-05 CA CA002466251A patent/CA2466251A1/fr not_active Abandoned
- 2002-11-05 AU AU2002366446A patent/AU2002366446A1/en not_active Abandoned
- 2002-11-05 WO PCT/US2002/035501 patent/WO2003066806A2/fr not_active Ceased
- 2002-11-05 EP EP02806003A patent/EP1451308A4/fr not_active Withdrawn
- 2002-11-05 JP JP2003566157A patent/JP2005517023A/ja active Pending

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0419890A2 (fr) *	1989-09-29	1991-04-03	American Cyanamid Company	Formulations pharmaceutiques stables pour des composés antinéoplastiques avec plus d'un groupement éthylèneimine et procédé
WO1997007674A1 (fr) *	1995-08-29	1997-03-06	Pentose Pharmaceuticals, Inc.	Procedes et compositions de modification selective d'acides nucleiques
WO2002055095A2 (fr) *	2000-11-06	2002-07-18	Vi Technologies Inc	Procedes et reactifs pour therapie immunomodulatrice extracorporelle

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CHAPMAN JOHN: "Progress in improving the pathogen safety of red cell concentrates.", VOX SANGUINIS, vol. 78, no. Suppl. 2, July 2000 (2000-07-01), pages 203 - 204, XP008004989, ISSN: 0042-9007 *
FAST-L: "Treatment of human leukocytes with inactine-TM results in loss of function and induction of apoptosis", BLOOD, vol. 96, no. 11, 16 November 2000 (2000-11-16), pages 61A, XP001073993 *
KASERMANN FABIAN ET AL: "Virus inactivation and protein modifications by ethyleneimines", ANTIVIRAL RESEARCH, vol. 52, no. 1, October 2001 (2001-10-01), pages 33 - 41, XP002296019, ISSN: 0166-3542 *
PURMAL ANDREI ET AL: "Process for the preparation of pathogen-inactivated RBC concentrates by using PEN110 chemistry: Preclinical studies", TRANSFUSION (BETHESDA), vol. 42, no. 2, February 2002 (2002-02-01), pages 139 - 145, XP002296020, ISSN: 0041-1132 *
RICHTER H I ET AL: "[Extracorporeal photopheresis in therapy-refractory disseminated discoid lupus erythematosus]", DER HAUTARZT;ZEITSCHRIFT FUR DERMATOLOGIE, VENEROLOGIE, UND VERWANDTE GEBIETE. GERMANY JUN 1998, vol. 49, no. 6, June 1998 (1998-06-01), pages 487 - 491, XP002203620, ISSN: 0017-8470 *

Also Published As

Publication number	Publication date
CA2466251A1 (fr)	2003-08-14
WO2003066806A3 (fr)	2003-12-24
AU2002366446A1 (en)	2003-09-02
JP2005517023A (ja)	2005-06-09
WO2003066806A2 (fr)	2003-08-14
EP1451308A2 (fr)	2004-09-01

Publication	Publication Date	Title
EP1416884A4 (fr)	2007-03-07	Administration d'agents potentiellement therapeutiques
IL196301A0 (en)	2009-09-22	Medicament for the treatment of hapatitis c
IL156595A0 (en)	2004-01-04	Therapeutic heterocyclic compounds
GB0013378D0 (en)	2000-07-26	Use of therapeutic benzamide derivatives
GB0305150D0 (en)	2003-04-09	Use of therapeutic compounds
GB0108930D0 (en)	2001-05-30	Therapeutic agents
GB0113839D0 (en)	2001-08-01	Therapeutic agents
HUP0500734A3 (en)	2005-12-28	Use of 2-alkoxyphenyl-substituted imidazotriazinones
GB0111191D0 (en)	2001-06-27	Therapeutic agents
GB0119025D0 (en)	2001-09-26	Compounds and their therapeutic use
EP1451308A4 (fr)	2004-11-17	Utilisation therapeutique de composes aziridino
EP1377289A4 (fr)	2008-09-10	Composes heterocycliques a utilisation therapeutique
GB2376943B (en)	2005-03-16	Compounds and their therapeutic use
GB0024517D0 (en)	2000-11-22	Use of medicaments
GB0112237D0 (en)	2001-07-11	Compounds and their therapeutic use
GB0128122D0 (en)	2002-01-16	Therapeutic use
GB0123991D0 (en)	2001-11-28	New therapeutic use
GB0108973D0 (en)	2001-05-30	Therapeutic agents
GB0130736D0 (en)	2002-02-06	Compounds and their therapeutic use
GB0128512D0 (en)	2002-01-23	Compounds and their therapeutic use
GB0104615D0 (en)	2001-04-11	Treatment of technetium
GB0105097D0 (en)	2001-04-18	Treatment of technetium
GB0118627D0 (en)	2001-09-19	Use of compounds in therapy
GB0128088D0 (en)	2002-01-16	Therapeutic use
GB0128126D0 (en)	2002-01-16	Therapeutic use

Legal Events

Date	Code	Title	Description
2004-07-16	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2004-09-01	17P	Request for examination filed	Effective date: 20040524
2004-09-01	AK	Designated contracting states	Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR
2004-09-01	AX	Request for extension of the european patent	Extension state: AL LT LV MK RO SI
2004-11-10	RIC1	Information provided on ipc code assigned before grant	Ipc: 7A 61P 35/00 B Ipc: 7A 61P 37/00 B Ipc: 7A 61K 31/395 B Ipc: 7A 61K 35/14 A
2004-11-17	A4	Supplementary search report drawn up and despatched	Effective date: 20041004
2005-10-21	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2005-12-07	18D	Application deemed to be withdrawn	Effective date: 20050601