EP1451209A4 - Tetra-,penta-,hexa- and heptapeptides having antiangiogenic activity - Google Patents

Tetra-,penta-,hexa- and heptapeptides having antiangiogenic activity

Info

Publication number: EP1451209A4
Authority: EP; European Patent Office
Prior art keywords: heptapeptides; hexa; penta; tetra; antiangiogenic activity
Prior art date: 2001-10-31
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP02789322A

Other languages

German (de)

French (fr)

Other versions

EP1451209A2 (en

Inventor

Fortuna Haviv

Michael F Bradley

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Abbott Laboratories

Original Assignee

Abbott Laboratories

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-10-31

Filing date

2002-10-30

Publication date

2009-06-03

2001-10-31 Priority claimed from US10/000,540 external-priority patent/US20030119745A1/en

2001-10-31 Priority claimed from US10/000,711 external-priority patent/US20030105025A1/en

2002-10-04 Priority claimed from US10/263,811 external-priority patent/US20030105022A1/en

2002-10-30 Application filed by Abbott Laboratories filed Critical Abbott Laboratories

2004-09-01 Publication of EP1451209A2 publication Critical patent/EP1451209A2/en

2009-06-03 Publication of EP1451209A4 publication Critical patent/EP1451209A4/en

Status Withdrawn legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Ophthalmology & Optometry (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Dermatology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Rheumatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Vascular Medicine (AREA)
Biophysics (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pain & Pain Management (AREA)
Immunology (AREA)
Urology & Nephrology (AREA)
Gynecology & Obstetrics (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

EP02789322A 2001-10-31 2002-10-30 Tetra-,penta-,hexa- and heptapeptides having antiangiogenic activity Withdrawn EP1451209A4 (en)

Applications Claiming Priority (7)

Application Number	Priority Date	Filing Date	Title
US263811		1988-10-28
US540		1995-06-27
US10/000,540 US20030119745A1 (en)	2001-10-31	2001-10-31	HEXA- and heptapeptides having antiangiogenic activity
US10/000,711 US20030105025A1 (en)	2001-10-31	2001-10-31	Tri-and tetrapeptides having antiangiogenic activity
US7		2001-10-31
US10/263,811 US20030105022A1 (en)	2001-10-31	2002-10-04	Tetra-, penta-, hexa- and heptapeptides having antiangiogenic activity
PCT/US2002/034760 WO2003037266A2 (en)	2001-10-31	2002-10-30	Tetra-, penta-, hexa- and heptapeptides having antiangiogenic activity

Publications (2)

Publication Number	Publication Date
EP1451209A2 EP1451209A2 (en)	2004-09-01
EP1451209A4 true EP1451209A4 (en)	2009-06-03

Family

ID=32659830

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP02789322A Withdrawn EP1451209A4 (en)	2001-10-31	2002-10-30	Tetra-,penta-,hexa- and heptapeptides having antiangiogenic activity

Country Status (6)

Country	Link
EP (1)	EP1451209A4 (en)
JP (1)	JP2005512980A (en)
CA (1)	CA2466152A1 (en)
MX (1)	MXPA04004135A (en)
UY (1)	UY27523A1 (en)
WO (1)	WO2003037266A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20030125260A1 (en) *	2001-10-31	2003-07-03	Fortuna Haviv	Tetra-and pentapeptides having antiangiogenic activity

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5780426A (en) *	1995-06-07	1998-07-14	Ixsys, Incorporated	Fivemer cyclic peptide inhibitors of diseases involving αv β3
US5932545A (en) *	1997-03-17	1999-08-03	Abbott Laboratories	Antiangiogenic drug to treat cancer, arthritis and retinopathy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT1078002E (en) *	1998-05-22	2008-09-02	Abbott Lab	Peptide antiangiogenic drugs

2002
- 2002-10-30 CA CA002466152A patent/CA2466152A1/en not_active Abandoned
- 2002-10-30 EP EP02789322A patent/EP1451209A4/en not_active Withdrawn
- 2002-10-30 WO PCT/US2002/034760 patent/WO2003037266A2/en not_active Ceased
- 2002-10-30 UY UY27523A patent/UY27523A1/en not_active Application Discontinuation
- 2002-10-30 JP JP2003539612A patent/JP2005512980A/en active Pending
- 2002-10-30 MX MXPA04004135A patent/MXPA04004135A/en unknown

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5780426A (en) *	1995-06-07	1998-07-14	Ixsys, Incorporated	Fivemer cyclic peptide inhibitors of diseases involving αv β3
US5932545A (en) *	1997-03-17	1999-08-03	Abbott Laboratories	Antiangiogenic drug to treat cancer, arthritis and retinopathy

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MIYASAKI KT ET AL: "Bactericidal Activities of Synthetic Human Leukocyte Cathepsin G-Derived Antibiotic Peptides and Congeners against Actinobacillus actinomycetemcomitans and Capnocytophaga sputigena", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 37, no. 12, December 1993 (1993-12-01), pages 2710 - 2715, XP002523772 *

Also Published As

Publication number	Publication date
CA2466152A1 (en)	2003-05-08
EP1451209A2 (en)	2004-09-01
JP2005512980A (en)	2005-05-12
WO2003037266A3 (en)	2003-12-11
MXPA04004135A (en)	2004-07-08
UY27523A1 (en)	2003-05-30
WO2003037266A2 (en)	2003-05-08

Publication	Publication Date	Title
GB2380983B (en)	2005-01-05	Modular overhead console assembly
EP1401817A4 (en)	2005-11-02	Isoquinoline compounds having antiinfective activity
AU148399S (en)	2002-07-12	A headset
AU143396S (en)	2001-04-04	Robot
GB0006350D0 (en)	2000-05-03	Joystick controller
GB0002847D0 (en)	2000-03-29	Ampligier arrangement
HUP0402171A3 (en)	2008-08-28	Pyrazolopyrimidinone derivatives having pde7-inhibitory activity
AU144371S (en)	2001-07-05	Torch
AU145539S (en)	2001-10-05	A headset
AU8838601A (en)	2002-06-03	Antiangiogenic agents
EP1445062A4 (en)	2006-08-09	Work support
IL154364A0 (en)	2003-09-17	Arylalkane-sulfonamides having endothelin-antagonist activity
EP1450841A4 (en)	2007-01-24	Tri-, tetra-, and penta-peptides having antiangiogenic activity
PL368745A1 (en)	2005-04-04	Peptides having antiangiogenic activity
GB2383410B (en)	2005-10-12	Joystick
EP1451209A4 (en)	2009-06-03	Tetra-,penta-,hexa- and heptapeptides having antiangiogenic activity
GB0214196D0 (en)	2002-07-31	Interference suppression
GB0010443D0 (en)	2000-06-14	A floor protector
AU2002353922A1 (en)	2003-05-12	Tetra-, penta-, hexa- and heptapeptides having antiangiogenic activity
HK1068900A (en)	2005-05-06	Tetra-, penta-, hexa- and heptapeptides having antiangiogenic activity
GB2385556B (en)	2005-01-12	Work support
SI2177530T1 (en)	2011-09-30	Octapeptide having antiangiogenic activity
GB0101116D0 (en)	2001-02-28	Activity board accessory
GB0105305D0 (en)	2001-04-18	Headset
GB0029467D0 (en)	2001-01-17	Crb

Legal Events

Date	Code	Title	Description
2004-07-16	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2004-09-01	17P	Request for examination filed	Effective date: 20040528
2004-09-01	AK	Designated contracting states	Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR
2004-09-01	AX	Request for extension of the european patent	Extension state: AL LT LV MK RO SI
2005-05-06	REG	Reference to a national code	Ref country code: HK Ref legal event code: DE Ref document number: 1068900 Country of ref document: HK
2009-06-03	A4	Supplementary search report drawn up and despatched	Effective date: 20090506
2009-10-02	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2009-11-04	18D	Application deemed to be withdrawn	Effective date: 20090805
2011-06-17	REG	Reference to a national code	Ref country code: HK Ref legal event code: WD Ref document number: 1068900 Country of ref document: HK