EP1334047B1 - Dispositif pour stocker et debiter des compositions aptes a l'ecoulement - Google Patents
Dispositif pour stocker et debiter des compositions aptes a l'ecoulement Download PDFInfo
- Publication number
- EP1334047B1 EP1334047B1 EP01993384A EP01993384A EP1334047B1 EP 1334047 B1 EP1334047 B1 EP 1334047B1 EP 01993384 A EP01993384 A EP 01993384A EP 01993384 A EP01993384 A EP 01993384A EP 1334047 B1 EP1334047 B1 EP 1334047B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- chamber
- film
- chambers
- substance
- area
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
- B65D81/32—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
- B65D81/3261—Flexible containers having several compartments
- B65D81/3266—Flexible containers having several compartments separated by a common rupturable seal, a clip or other removable fastening device
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
- B65D81/32—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
- B65D81/3294—Thermoformed trays or the like with a plurality of recesses for different materials located in different recesses
Definitions
- the invention relates to a device for storing and dispensing a flowable after mixing composition of at least two components.
- the first recess may contain a small amount of liquid, in the other recess may be inserted a brush.
- a disposable container which has troughs for storing a medicament and an applicator. Both troughs are protected from contamination by a peelable cover film.
- the medicament is transferred to the well containing the applicator by pressing on the well containing the medicament to wet the applicator. It is stated that this is only possible if the cover film is not glued to the container in the transition region of the two troughs.
- a care set which has two wells in a body, containing on the one hand a care substance and the other a swab. Through a sealing film containing the care substance and the swab main body is protected from contamination.
- EP 0 895 943 A discloses a device for storing and applying a flowable substance, comprising a container made of two films which are joined together to form two chambers for holding substances and a pocket separate from the chambers for removing the mixture of the two substances are, wherein the separation between a chamber and the pocket has a selectively openable passage area.
- pressure is first exerted on the one chamber, whereby the substance contained therein via the passage area is transferred to the second chamber.
- an overpressure builds up in the second chamber, which leads to a bulge of one of the chambers forming the chambers.
- it is necessary for the device In order to prevent the mixture from flowing back into the first chamber, it is necessary for the device to be bent in the area between the two chambers. Here, operating errors are not excluded.
- a disadvantage of the devices known from the prior art is therefore that they are only conditionally suitable for dispensing homogeneous compositions which can be obtained by mixing two substances stored separately in the device, in particular in the case of compositions whose individual constituents are in different volumes or aggregate states present, a homogeneous and reproducible mixing result can often not be guaranteed.
- the primary object of the present invention is to provide an improved apparatus for storing and dispensing mixtures.
- Another object can be seen to provide a device that allows the storage and deployment of larger amounts of substance without the mixing result is impaired.
- a further object can be seen to provide a multi-chamber device which largely prevents backflow of the mixture to be delivered into one of the chambers of the device when dispensing.
- the apparatus enables storage, mixing and dispensing of flowable compositions, the individual ingredients of which may be stored separately prior to mixing in the apparatus.
- the device will characterized in that pressure is applied to the first chamber whereby the substance located in this chamber is transferred via the selectively openable passage area in the second chamber.
- the passage area to be selectively opened thus represents, as it were, a type of predetermined breaking point.
- the second chamber as in the device according to EP 0 895 943 A, can not completely absorb the first substance or only under difficult conditions, only part of the first substance can be mixed with the second substance. This is disadvantageous, since a reproducible mixing result is required, in particular in the medical field. Mixtures with concentration deviations of individual components are useless in many cases.
- the present invention defined in claim 1 solves this problem, since according to the invention, the second chamber is such that it can accommodate a first substance in addition to a second substance, both substances can be mixed in the device, without that the device previously opened must be, but this is easily possible after mixing.
- the at least one of the chambers forming the chambers of the device is preformed or plastically moldable at least in the region of the second chamber.
- the device according to the invention also makes it possible to follow the activation of the device in particular optically by exerting pressure on the first chamber.
- the transfer of the first substance from the first chamber into the second chamber causes a permanent increase in volume of the second chamber, which can be detected from the outside during the application.
- preformed in the sense of the invention is understood to mean a plastic, defined deformation or preforming of a film, wherein the film can be controlled and specifically transferred from this mold into another form. This includes pre-forming by both peelable sealing with a different foil as well as seal-free areas. Preforming can be achieved, for example, by deep drawing a film by means of deep drawing tools.
- Foils in the sense of the invention are then malleable, in particular plastically moldable, when they yield under deformation upon application of an external force (for example, by an internal pressure in a chamber building up when the device is activated), for example by permanent stretching.
- Suitable films which can be formed by activating the device preferably have no appreciable elasticity and thus have no appreciable resilience.
- a film is then stretchable in the sense of the invention if it can be permanently stretched or deformed by the internal pressure building up when the device is activated.
- the invention enables a minimum packing volume for the substances to be stored and mixed.
- the substances can be filled into the chambers of the device almost without the inclusion of atmospheric oxygen or other gases in the dead volume, since the required for mixing additional volume in the second chamber automatically provided with the transfer of the first substance from the first to the second chamber becomes.
- a similar effect can be achieved - but with great technical effort - by filling the device under vacuum.
- the volume not filled by the substance (dead volume) is replaced by a vacuum, which, after sealing the device and then exposing the device to atmospheric pressure, causes corresponding shrinkage of the volume regions under vacuum leads.
- the dead volume can be almost completely reduced.
- the device is particularly suitable for storing, mixing and dispensing substances that are present in different volumes in the device.
- the smaller volume substance substantially fully participates in the mixing process and prevents misdosing during mixing
- the substance with the larger volume is expediently stored in the first chamber in this regard.
- the passage area or areas to be selectively opened can be closed again if necessary.
- Backflow of the mixed substances into the other chamber is then virtually impossible, so that the mixed substances can be transferred into the discharge region by pressure action on the outer region of the films forming the second chamber.
- the volume of the first chamber is usually in the range of 0.01 to 100 ml, preferably in the range of 0.05 to 50 ml.
- the volume of the second chamber is preferably less than or equal to the volume of the first chamber, at least prior to activating the device, and is in the range of 0.001 to 100 ml, preferably in the range of 0.01 to 25 ml.
- a chamber has for example a diameter of 1 to 100 mm, preferably in the range of 5 to 50 mm.
- the total volume administered is usually in the range of 0.011 to 200 ml, preferably in the range of 0.06 to 75 ml.
- the increase in volume can be achieved, for example, by a substantially concave formation of the base film and a substantially convex formation of the cover film (from the point of view of the product filled into the chamber).
- the cover film is also somewhat deep-drawn in the region of the second chamber and connected to the second film in such a way that the deep-drawn region can bulge outwardly upon activation of the device.
- the cover sheet is first deep-drawn and then everted so that the dent in the film is on the side opposite the thermoforming tool.
- the material displacements that have occurred during deep drawing in the film and the tension associated therewith remain at least partially preserved during everting, so that the film as it were is in a quasi-preloaded state and can thus be turned inside out more easily when activated.
- the cover film thus produced is finally sealed onto the likewise deep-drawn base film.
- the inverted dent in the cover sheet and the dent in the base film show in the same direction and form between them the volume of the second chamber in the storage condition.
- the base film seen in cross-section on several wave crests and wave troughs, wherein the film in the Area of a wave trough can be peelbar sealed with the cover sheet, so that the chamber is divided into several compartments.
- the device is therefore also suitable for storing and mixing more than two substances.
- the second substance which is expediently peelably sealed in the center of the second chamber, is initially surrounded by a groove-like shape when the device is activated by the first substance transferred from the first chamber into the second chamber without direct contact. With increasing pressure on the first chamber and transfer of an increasing amount of second substance, the seal begins to dissolve in the region of the wave trough, whereby the first substance begins to wet the second substance.
- Another possibility is to peelably seal the second chamber in an edge region or to press the two films forming the chamber in this area lying flat on each other without peelably sealing them in this region.
- a non-peelable sealing area adjoins this edge region, which ultimately and especially when activating the device seals the chamber to the outside.
- This non-peelable (firmly sealed) sealing area is only interrupted in each case by a peelable passage area at the point at which the second chamber opens into the dispensing area or the connection between the first and second chamber is to be established.
- the increase in volume of the second chamber takes place upon activation of the device in that the cover sheet can be detached from the base film in this area or lifted off.
- peelably sealed or unsealed edge areas after the increase in volume due to activation of the device, may be more prone to recovery than films converted from a convex shape to a concave shape upon activation.
- An increase in volume of the second chamber can also be achieved, for example, by virtue of the fact that at least one of the films forming the second chamber is deformable or expandable, in particular plastically deformable.
- the width of the peelbar sealed edge region is basically arbitrary and depending on the desired increase in volume, a width in the range of 0.1 to 40 mm, preferably from 0.5 to 20 mm has been proven.
- the selectively openable regions or the peelably sealed regions preferably open when a hydrostatic pressure in the range from 3 to 300 N / cm 2 , particularly preferably in the range from 15 to 150 N / cm 2 , is applied to them by a flowable substance Area is exercised.
- the pressure to be used for opening the selectively openable regions may vary for each selectively openable region. This allows a directed transfer of the substances to be mixed in the respective chambers up to the application area.
- slight changes in the geometry of the device, in particular in the region of the second chamber, may occur when the device is activated.
- one of the films forming the chamber bulges slightly with increasing pressure build-up to the outside.
- the second chamber is connected via a selectively openable passage area with the discharge area.
- the mixed composition can be applied to the second chamber by exerting pressure, without the need for additional devices to open the device.
- the passage region to the first chamber is closed by folding over.
- application area in the sense of the invention means the area of the device via which the mixed composition is emptied.
- the dispensing area is designed such that a secure, uniform spreading can be ensured.
- the substance By introducing flow barriers into the dispensing area, the substance is influenced during the outflow through the dispensing area in such a way that a slow exit from the dispensing area at its mouth is ensured. This also prevents splashing of the substance by exerting high pressure on the second chamber upon sudden opening of the passage area.
- the increase of the flow resistance and thus the obstruction of the outflow of the substance can be achieved by an extension, optionally with change of direction, of the flow path around the barriers or by the reduction of the flow cross-section through staggered sealing points or sealing webs.
- an increase in the flow resistance can be achieved by a rectilinear narrowing of the flow cross section in the discharge region.
- a narrowing by a factor of 1.5 to 5, preferably by a factor of 2, provided.
- Such a device is particularly suitable when low-viscosity substances without further aids purposeful, easy and without spillage should be applied.
- the device may have a dispensing area which is arranged geometrically to the passage area such that the longitudinal axis of the dispensing area does not extend through the passage area.
- the dispensing area can have an enlarged volume, in particular in the part adjacent to the passage area. It is particularly preferred if the dispensing area is designed as a pocket.
- a suitable valve is, for example, a flexible film (hereinafter referred to as valve film), which is fastened in the passage region between the two chambers, for example on the base film and projects into the second chamber.
- valve film a flexible film
- the first substance can be transferred from the first chamber into the second chamber.
- the valve foil prevents the substances located in the second chamber from flowing back, blocking the passage area.
- This embodiment brings u.a. the advantage that the device in the passage area between the two chambers need not be kinked after activation in order to exclude that substance flows back into the first chamber.
- valve film additionally completely or partially lines the first chamber and optionally extends into the firmly sealed edge region of the first chamber. It may be sufficient if the valve film adheres to the base film only in the passage area at its top.
- the selectively openable passage area in combination with the valve film can also be realized, for example, in the following way:
- the valve film is connected, for example, to the cover film in the region of the first and second chambers and in the passage area.
- the valve film has an opening in the region of the first chamber in the vicinity of the selectively openable passage region to the second chamber, which has been punched out of the valve film, for example.
- the valve film also has in the region of second chamber on a tab or tongue, which can be formed for example by punching or cutting a corresponding shape of the valve film.
- the separated in the region of the flap residual region of the valve film is not removed, but remains in the region of the second chamber.
- the valve film is preferably peelably sealed to the cover film only in the passage region.
- the substance Upon activation of the device, the substance is transferred from the first chamber through the opening in the valve foil via the selectively openable passageway area to the second chamber, with the tab of the valve foil lifting.
- the tab As soon as substantially the entire amount of the first substance has been transferred to the second chamber, the tab is pressed against the cover sheet in the region of the second chamber or in the existing free-punching by the build-up internal pressure in the second chamber and pressure relief of the first chamber prevents in this way the backflow of the substance into the first chamber.
- in the selectively openable passage area between the first chamber and the second chamber may be a third chamber which is filled with a third substance.
- the third chamber is first opened in this case, and the first substance emerging from the first chamber merges with the third substance located in the third chamber before finally entering the second chamber, in which the actual mixing process takes place.
- This arrangement is particularly suitable for the intensive mixing of the same or different liquids, which are located in the first and second chamber with, for example, a powder, which is located in the intermediate third chamber.
- the third chamber can be particularly intensively flushed by repeated, mutual exerting pressure on the first and second chamber and the substances contained therein.
- a volume reservoir located in the first and / or second chamber is advantageous.
- the device is usually a unit-dose.
- the device is suitable for storing and dispensing all Substances that require reproducible mixing and dosage that is largely independent of the user.
- the device has proven itself in human and veterinary medicine as well as in the dental field.
- the substances to be stored are usually liquids, pastes and / or solids.
- the solids may be present in powder, tablet or granular form.
- the device is preferably suitable for storing, mixing and dispensing compositions selected from human and animal medicaments, wound cleansing agents, dental products, adhesives, impression materials, paints, in particular 2-component paints, foods to be stored separately or their constituents.
- the device essentially comprises a first base or bottom foil and a second top or top foil, which in turn may be formed as multilayer foils.
- At least one of the films is plastically deformable, preferably thermoformable under deformation.
- the films used are preferably those which have a sufficient diffusion tightness.
- the films should also be resistant to aggressive substances, for example corrosive and / or solvent-containing substances.
- the films are stretched or are in the unstretched state before the device is activated.
- the film components may be selected from plastic, metal and ceramic films.
- plastic films are conceivable, for example: PE, PP, PTFE, PET, PA, PBT, PVC, EVA, PVF (polyvinyl fluoride).
- Possible metal foils are, for example: Al, Sn, Au, Ag, Fe, Pb.
- Ceramic films are to be understood as meaning films which have, for example, an SiO 2 -containing layer.
- the film structure is basically arbitrary and is oriented i.a. on the nature of the substances to be stored.
- a film structure with the sequence from the outside to the inside has proved to be advantageous PET, Al, PET, PE or PP, Al, PET, PE, if appropriate also without PET film as center film.
- the films are preferably connected to each other with the exception of the chambers forming areas.
- connection of the first with the second film can be done for example by heat sealing, cold sealing, gluing and / or ultrasonic welding with sonotrodes.
- a multilayer structure of the first and second film can be achieved by laminating, calendering, laminating various monofilm layers, if appropriate also by vapor deposition, for example with metals.
- the foils are preferably designed such that they are connected to one another in a region surrounding the chamber by two sealing seams arranged at a distance from one another.
- the shape of the device is basically arbitrary, but preferably adapted to the nature of the stored substances.
- the chambers are preferably round (circular or oval) but optionally also square (square, rectangular or triangular).
- the passageway area is such that it forms a tight seal in the storage condition, both between the two chambers and to the area over which the composition is to be applied.
- the selectively openable passage area or the predetermined breaking point can be achieved, for example, by cold sealing, heat sealing, ultrasonic welding or gluing, wherein in heat sealing one in comparison to the other Seal areas of different energy input, preferably lower energy input takes place.
- This can be regulated by temperature, pressure and / or holding time.
- Another possibility is to introduce in the region of the predetermined breaking point between the first and the second film adhesion-reducing foreign particles such as Peelfolienstienstlinge or Hotmeltklebeumming.
- the first and the second film adhesion-reducing foreign particles such as Peelfolienstienstlinge or Hotmeltklebe.
- top and bottom film are preferably used as top and bottom film
- the dispensing area is preferably open to one side, i. formed in pocket-like, and optionally designed so that a dispensing instrument or an applicator can also bring in the storage condition.
- the dispensing area can also serve as an application device itself.
- the separation between the chamber or chambers and the dispensing area is designed with respect to the distance as well as with regard to the strength of the adhesion so that there is a further predetermined breaking point.
- the optionally existing application instrument is preferably designed brush or swab-like.
- An application instrument with a spherical, brush or brush hair-bearing tip has proven to be beneficial.
- pipettes, cotton swabs, sponges, spatulas or spray heads sealed in the dispensing area may be used as the application instrument or devices.
- a dispensing instrument located in the dispensing region or introduced only at this time or later is wetted when the device is activated and can then be used to apply the released substance.
- the application instrument is moved in the direction of the second chamber in order to release the passage area to be selectively opened. This also wets the dispensing instrument.
- the application instrument can be reinserted into the pocket.
- the application area or the application instrument is designed so that upon reinsertion of this wetting of the outer portion of the application instrument does not take place.
- the device according to FIG. 1 has a base film (1) and a cover film (2). In region (3), the two films are peelably sealed together, whereby a selectively openable passage area between the two chambers (5) and (6) is formed. In FIG. 1, the dispensing area (4) also has a passage area to be selectively opened. In the chambers (5) and (6) there are two substances to be mixed (A) and (B). The volume of the second chamber (6) can be increased as soon as the device is activated by exerting external pressure on the first chamber (5).
- the base film (1) in the region of the second chamber (6) is curved concavely outwards and the cover film (2) convexly curved inwards or preformed.
- the substance (A) from the first chamber (5) is located after activation together with the substance (B) in the second chamber (6).
- the cover sheet (2) now also has, like the base sheet (1), a concavely convex shape (dashed line in FIG. 1).
- FIG. 2 shows a further possible embodiment of the device in cross section.
- the increase in volume of the second chamber (5) can be achieved by preforming the base film (1) in the region of the second Chamber (6) with wave crests (9) and troughs (10).
- the base film (1) with the cover film (2) can additionally be peelably sealed next to the passage region (3).
- Both substances (A) and (B) are located after the activation in the second chamber (6) whose volume has been increased by bulging of the wave trough (10) to an overall substantially concave shape (dashed line in Figure 2).
- FIG. 3 shows a further possible embodiment of the device in cross section.
- the base film (1) and cover film (2) are preformably preformed from one another. This deformation can be achieved, for example, by peelable sealing of the films in this region or by the film being pressed flat against one another in this region without being peelably sealed in this region.
- the base film (1) has been separated from the cover film (2) in the edge region (11) of the second chamber (6) after activation (dashed line in FIG. 3). Both substances (A) and (B) are now in the second chamber (6).
- the resistance in the dispensing area caused by the passage area to be selectively opened must be overcome.
- Figure 4 shows the device based on Figure 1 in plan view.
- the dispensing area (4) has flow barriers in the region (13) or is meander-shaped. This prevents splashing as the composition is dispensed from the device.
- a further film (12) is attached to the base film (1) and protrudes into the second chamber (6), wherein the film (12) is not necessarily deep drawn in the region of the second chamber.
- This film (12) performs a valve function which prevents that after activation of the device located in the second chamber (6) Substances (A) and (B) can get back into the first chamber (5), when for applying the composition comprising the substances (A) and (B), the second chamber (6) pressure is applied to the to open selectively passage area to be opened outwards in the discharge area.
- the selectively openable passage region (3) is located in this embodiment between the valve film (12) and the cover sheet (2).
- the dashed line in Figure 5 shows the device after activation.
- the cover film (2) has curved due to the built-up internal pressure in the second chamber (6) to the outside. This deformation of the cover film (2) leads to an increase in volume of the second chamber (6) and allows the inclusion of the two substances (A) and (B).
- the valve film (12) is in this case pressed against the cover film and thereby prevents the backflow of the mixture into the first chamber (5) without the device having to be bent in the passage region between the two chambers.
- the device also in the production of, for example, with ⁇ -rays or heat sterilizable packaging.
- the substance stored in the sealed device or the stored substances can be sterilized by the preforming according to the invention at least one of the films easily with the above-mentioned means, even if it comes here for example by increasing the temperature to outgassing of the stored substances without the device itself is activated or opened to the chamber or chambers adjacent selectively open passage areas.
- This type of use can also be used in devices that have only one chamber for storing a substance.
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Claims (20)
- Dispositif comportant une première et une seconde feuille (1, 2), une zone de débit (4), une première chambre (5) renfermant une première substance (A) et une seconde chambre (6) renfermant une seconde substance (B), les chambres (5, 6) étant reliées entre elles par l'intermédiaire d'une zone de passage (3) à ouverture sélective, au moins l'une des feuilles (1, 2) étant emboutie dans la zone des chambres (5, 6), caractérisé en ce qu'au moins l'une des feuilles (1, 2) est préformée ou selon le cas formable plastiquement dans la zone de la seconde chambre (6) de telle sorte qu'après l'activation du dispositif par l'ouverture de la zone de passage (3), la première substance (A) puisse être transférée substantiellement complètement dans la seconde chambre (6) en augmentant le volume de celle-ci, sans qu'un reflux notable du mélange (A + B) se produise dans la première chambre (5).
- Dispositif selon la revendication 1, les feuilles (1, 2) étant formées de façon concave-convexe dans la zone de la seconde chambre (6).
- Dispositif selon la revendication 1, au moins l'une des feuilles (1, 2) présentant dans la zone de la seconde chambre (6) une forme pouvant être obtenue par formage au moins partiel d'un renfoncement (10) dans une surface d'abord de forme concave.
- Dispositif selon la revendication 3, l'une des feuilles (1, 2) s'étendant jusqu'à l'autre feuille dans la zone du renfoncement (10) et étant scellée à celle-ci de façon pelable à l'endroit de contact.
- Dispositif selon la revendication 1, les feuilles formant les chambres étant préformées de façon séparable l'une de l'autre au moins dans une zone de bord de la seconde chambre (6).
- Dispositif selon la revendication 1, au moins une feuille pouvant se dilater dans la zone de la seconde chambre (6).
- Dispositif selon l'une quelconque des revendications précédentes, la seconde chambre (6) pouvant être reliée à la zone de débit (4) par l'intermédiaire d'une zone de passage (3) à ouverture sélective.
- Dispositif selon l'une quelconque des revendications précédentes, une troisième chambre se trouvant dans la zone de passage (3) à ouverture sélective entre la première (5) et la seconde chambre (6).
- Dispositif selon l'une quelconque des revendications précédentes, une troisième feuille (12), laquelle dépasse dans la seconde chambre (6), étant appliquée contre l'une des feuilles (1, 2) formant les chambres dans la zone de passage (3) entre les deux chambres (5, 6).
- Dispositif selon l'une quelconque des revendications précédentes, les chambres (5, 6) présentant des volumes différents avant l'activation.
- Dispositif selon l'une quelconque des revendications précédentes, comportant un applicateur.
- Dispositif selon la revendication 11, l'applicateur se trouvant dans la zone de débit (4).
- Dispositif selon l'une quelconque des revendications précédentes, la première substance (A) étant apte à l'écoulement et la seconde substance (B) étant solide.
- Dispositif selon l'une quelconque des revendications précédentes, des barrières d'écoulement (13) se trouvant dans la zone de débit (4).
- Dispositif selon l'une quelconque des revendications précédentes, la zone de passage (3) à ouverture sélective pouvant être ouverte suite à l'action d'une pression hydrostatique de l'ordre de 3 à 300 N/cm2.
- Utilisation du dispositif selon l'une quelconque des revendications précédentes, pour stocker, mélanger et/ou débiter des compositions aptes à l'écoulement.
- Utilisation selon la revendication 16, les compositions aptes à l'écoulement étant choisies parmi : substances médicamenteuses humaines et animales, agents de nettoyage de plaies, produits dentaires, colles, matériaux de moulage, peintures, substances alimentaires.
- Procédé de fabrication d'un dispositif selon l'une quelconque des revendications 1 à 15, comportant les étapes de : a) préparation d'une première feuille (1), b) emboutissage partiel de la première feuille (1) en formant deux chambres (5, 6), c) remplissage des deux chambres (5, 6) avec deux substances (A, B) destinées à être mélangées, d) application d'une seconde feuille (2), e) raccordement largement plan de la seconde feuille (2) à la première feuille (1) en ménageant les chambres (5, 6) et en formant une zone de passage (3) à ouverture sélective entre les deux chambres (5, 6).
- Procédé selon la revendication 18, la seconde feuille (2) étant préformée avant l'étape d) de façon convexe ou en forme d'onde dans la zone de la seconde chambre (6).
- Procédé selon la revendication 18, une troisième feuille (12) étant reliée avant l'étape d) à la première feuille (1) dans la zone de passage (3).
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10056212 | 2000-11-13 | ||
| DE10056212A DE10056212B4 (de) | 2000-11-13 | 2000-11-13 | Vorrichtung zum Lagern und Ausbringen von fließfähigen Zusammensetzungen, Verfahren zur Herstellung und Verwendung der Vorrichtung |
| PCT/EP2001/012865 WO2002038468A1 (fr) | 2000-11-13 | 2001-11-07 | Dispositif pour stocker et debiter des compositions aptes a l'ecoulement |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP1334047A1 EP1334047A1 (fr) | 2003-08-13 |
| EP1334047B1 true EP1334047B1 (fr) | 2005-09-21 |
Family
ID=7663138
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP01993384A Expired - Lifetime EP1334047B1 (fr) | 2000-11-13 | 2001-11-07 | Dispositif pour stocker et debiter des compositions aptes a l'ecoulement |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7097075B2 (fr) |
| EP (1) | EP1334047B1 (fr) |
| JP (1) | JP3801988B2 (fr) |
| AT (1) | ATE304978T1 (fr) |
| AU (2) | AU2181802A (fr) |
| CA (1) | CA2422640C (fr) |
| DE (2) | DE10056212B4 (fr) |
| WO (1) | WO2002038468A1 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USD1106454S1 (en) | 2023-06-14 | 2025-12-16 | Solventum Intellectual Properties Company | Dental material applicator with partitioned packaging |
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|---|---|---|---|---|
| US6685013B2 (en) | 1994-07-13 | 2004-02-03 | Centrix, Inc. | Single patient dose medicament dispenser with applicator |
| DE10237317B4 (de) | 2002-08-15 | 2010-04-08 | 3M Espe Ag | Enzymhaltige Zusammensetzung, Verfahren zu deren Herstellung und deren Verwendung |
| DE10243401B4 (de) * | 2002-09-18 | 2004-07-29 | Voco Gmbh | Verpackung zum Lagern von Substanzen und Verfahren zum Herstellen eines direkt applizierbaren Gemisches zweier Substanzen aus dieser Verpackung |
| DE10251050B3 (de) | 2002-11-02 | 2004-01-29 | Kettenbach Gmbh & Co. Kg | Vorrichtung zum Lagern und Ausbringen viskoser Substanzen |
| WO2004041107A2 (fr) | 2002-11-02 | 2004-05-21 | Kettenbach Gmbh & Co. Kg | Dispositif de stockage et d'application de substances visqueuses |
| EP1498098B1 (fr) | 2003-07-14 | 2006-05-03 | 3M Espe Ag | Composition adhésive d'une polarité réduite après sa polymérisation |
| DE10345589A1 (de) * | 2003-09-29 | 2005-05-04 | Andre Schelbach | Flakon |
| EP1526092A1 (fr) * | 2003-10-24 | 2005-04-27 | 3M Espe AG | Dispositif pour stocker et débiter des substances aptes à l'écoulement |
| DE10360627B4 (de) * | 2003-12-19 | 2006-02-23 | Heraeus Kulzer Gmbh | Mehrkomponentenkartusche und ihre Anwendung |
| JP2007534384A (ja) * | 2004-04-23 | 2007-11-29 | ミスティック ファーマシューティカルズ, インコーポレイテッド | 複数の単位用量の薬物送達システム |
| EP1600141B1 (fr) * | 2004-05-24 | 2013-04-17 | 3M Deutschland GmbH | Compositions contenant une enzyme active collagénolytique et son utilisation pour le traitement des carries dentaires |
| ATE439116T1 (de) * | 2004-09-24 | 2009-08-15 | 3M Espe Ag | Dentalklebstoffzusammensetzung |
| US20090308888A1 (en) * | 2004-11-15 | 2009-12-17 | Teikokumedix Co., Ltd | Package filled with gel or paste content and gas |
| US7374040B2 (en) * | 2004-12-22 | 2008-05-20 | 3M Innovative Properties Company | Devices for storing and dispensing compositions |
| EP1833739A2 (fr) * | 2004-12-30 | 2007-09-19 | Medmix Systems AG | Dispositif de distribution de composants multiples, pour substances liquides et pulverulentes |
| US20080302678A1 (en) * | 2005-03-30 | 2008-12-11 | Rodney Darryl Hunwisk | Edible Food Composition and Various Packaging Arrangments |
| JP4493560B2 (ja) * | 2005-07-13 | 2010-06-30 | 花王株式会社 | 二剤混合容器 |
| EP1754464A1 (fr) * | 2005-08-17 | 2007-02-21 | 3M Innovative Properties Company | Composition dentale contenant une enzyme |
| JP2007090138A (ja) * | 2005-09-27 | 2007-04-12 | Yokogawa Electric Corp | 化学処理用カートリッジおよびその使用方法 |
| DE102006018038B4 (de) * | 2006-04-11 | 2008-02-14 | Beiersdorf Ag | Mehrkammerbehältnis mit Mischereinheit zur Aufbewahrung und Ausgabe fluider Medien |
| US20100047403A1 (en) * | 2006-10-30 | 2010-02-25 | Elizabeth Johnson | Pouch container for food product |
| CA2675030C (fr) * | 2007-01-09 | 2015-06-09 | Mystic Pharmaceuticals, Inc. | Dispositifs a cartouche intranasaux |
| EP2134621A1 (fr) * | 2007-03-27 | 2009-12-23 | Cryovac, Inc. | Réceptacle pour attendrissement de la viande à la demande |
| US8579856B2 (en) | 2007-05-16 | 2013-11-12 | Mystic Pharmaceuticals, Inc. | Unit dose drug delivery platform |
| WO2008144439A1 (fr) * | 2007-05-16 | 2008-11-27 | Mystic Pharmaceuticals, Inc. | Conteneurs de distribution de doses à unité de combinaison |
| WO2009036422A1 (fr) | 2007-09-14 | 2009-03-19 | Mystic Pharmaceuticals, Inc. | Procédé de façonnage d'un réceptacle par emboutissage profond |
| EP2200562B1 (fr) * | 2007-10-26 | 2014-04-23 | 3M Innovative Properties Company | Composition dentaire pour detecter la presence de bacteries, kit and utilisation comprenant cette composition |
| DE102007059533A1 (de) | 2007-12-06 | 2009-06-10 | Thinxxs Microtechnology Ag | Mikrofluidische Speichervorrichtung |
| EP2662050B1 (fr) | 2008-01-23 | 2017-09-06 | 3M Innovative Properties Company | Dispositif pour appliquer un matériau dentaire et son procédé de fabrication |
| KR100941914B1 (ko) * | 2008-06-03 | 2010-02-11 | 이재호 | 가압배출구가 구비된 파우치팩 |
| US8376183B1 (en) * | 2008-06-10 | 2013-02-19 | Ags I-Prop, Llc | Fluid dispenser having multiple chambers |
| US20100108671A1 (en) * | 2008-11-04 | 2010-05-06 | William Cho | Pressure Relief System |
| US8398324B2 (en) * | 2009-03-19 | 2013-03-19 | Jbl Radical Innovations, Llc | Vial for delivering contents onto a substrate |
| WO2010109610A1 (fr) * | 2009-03-25 | 2010-09-30 | 株式会社モリモト医薬 | Conteneur de composition pharmaceutique |
| JP5896897B2 (ja) * | 2010-03-29 | 2016-03-30 | 株式会社モリモト医薬 | 経口摂取用の医薬組成物容器 |
| PL2585023T3 (pl) | 2010-06-23 | 2019-12-31 | Gambro Lundia Ab | Przygotowanie roztworów medycznych ze sproszkowanego materiału |
| EP2415420A1 (fr) * | 2010-07-29 | 2012-02-08 | 3M Innovative Properties Co. | Emballage pour matériau dentaire et son procédé de fabrication |
| EP2412361A1 (fr) | 2010-07-29 | 2012-02-01 | 3M Innovative Properties Company | Kit de pièces, procédé de fabrication et utilisation correspondante |
| DE102010033015B4 (de) * | 2010-07-31 | 2016-03-17 | Gaplast Gmbh | Einmal-Applikator |
| USD690790S1 (en) | 2012-06-15 | 2013-10-01 | S.C. Johnson & Son, Inc. | Applicator |
| USD690791S1 (en) | 2012-06-15 | 2013-10-01 | S.C. Johnson & Son, Inc. | Applicator |
| US9364872B2 (en) | 2010-08-10 | 2016-06-14 | S. C. Johnson & Son, Inc. | Single-dose applicator and method |
| USD690792S1 (en) | 2012-06-15 | 2013-10-01 | S.C. Johnson & Son, Inc. | Applicator |
| US8794293B2 (en) | 2010-08-10 | 2014-08-05 | S.C. Johnson & Son, Inc. | Single dose applicator and method |
| US8585659B2 (en) | 2011-05-31 | 2013-11-19 | Mystic Pharmaceuticals, Inc. | Piercing device for drug delivery systems |
| US8806842B1 (en) * | 2011-06-20 | 2014-08-19 | The Packaging Consultants Group | Disposable multiple compartment mixing and dispensing container |
| EP2591748A1 (fr) * | 2011-11-11 | 2013-05-15 | 3M Innovative Properties Company | Dispositif de distribution d'un matériau dentaire et un procédé de distribution |
| USD690793S1 (en) | 2012-06-15 | 2013-10-01 | S.C. Johnson & Son, Inc. | Applicator |
| USD712506S1 (en) | 2012-11-09 | 2014-09-02 | S.C. Johnson & Son, Inc. | Composition |
| DE102012220790A1 (de) * | 2012-11-14 | 2014-05-15 | Henkel Ag & Co. Kgaa | Behälter zur Ausgabe eines Mehrkomponentengemisches |
| US9045275B2 (en) | 2013-10-30 | 2015-06-02 | Le Papillon Bioplan | Container for dispensing a combination product |
| DE102013226706A1 (de) * | 2013-12-19 | 2015-06-25 | Beiersdorf Ag | Leichtverpackung mit Dosierkammer |
| WO2015148215A1 (fr) | 2014-03-25 | 2015-10-01 | 3M Innovative Properties Company | Procédé pour le traitement sélectif de la surface d'une céramique dentaire |
| EP3045184B1 (fr) | 2015-01-13 | 2019-01-09 | ECP Entwicklungsgesellschaft mbH | Récipient pour un dispositif de pompe cardiaque et procédé de fonctionnement d'un dispositif de pompe cardiaque |
| GB2536968A (en) * | 2015-04-02 | 2016-10-05 | Kraft Foods R&D Inc | Improvements in and relating to packaging |
| US10011399B1 (en) * | 2015-05-15 | 2018-07-03 | Loren S. Adell | Fabrication of polymeric dental devices and aids |
| US10086988B2 (en) * | 2016-04-08 | 2018-10-02 | Katie Rose Grobman | Configurable packet for controllable mixing and dispensing of condiments |
| HUE054071T2 (hu) * | 2016-05-25 | 2021-08-30 | Claudia Mattern | Kétrészes mûanyag öntvénykészlet |
| US11510851B2 (en) | 2016-10-05 | 2022-11-29 | 3M Innovative Properties Company | Application device with redox initiator system, method of production and use thereof |
| DE102016012651A1 (de) | 2016-10-24 | 2018-04-26 | Beiersdorf Ag | Mehrkomponentenapplikator |
| DE102016012650A1 (de) | 2016-10-24 | 2018-04-26 | Beiersdorf Ag | Mehrkomponentenapplikator |
| IT201800009131A1 (it) * | 2018-10-03 | 2020-04-03 | Orofino Pharmaceuticals Group Srl | Cartuccia deformabile per dispositivo di iniezione |
| WO2022137093A1 (fr) * | 2020-12-21 | 2022-06-30 | 3M Innovative Properties Company | Dispositif de stockage et de distribution de compositions fluidifiables |
| CN116459070A (zh) * | 2023-05-04 | 2023-07-21 | 济南明然医疗器械有限公司 | 一种富氧眼药水滴取装置 |
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| US2176923A (en) * | 1938-10-20 | 1939-10-24 | Squibb & Sons Inc | Packaging |
| US3145838A (en) * | 1961-09-26 | 1964-08-25 | Laguna Scient Ind | Departmentalized package |
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| US3835834A (en) * | 1972-02-24 | 1974-09-17 | J Brown | Culture transporter |
| JPS58116584A (ja) | 1981-12-29 | 1983-07-11 | パイオニアビデオ株式会社 | 画像情報処理装置 |
| JPH0286177A (ja) | 1988-09-22 | 1990-03-27 | Fujitsu Ltd | 光電変換装置 |
| DE69111480T2 (de) * | 1990-02-14 | 1996-03-14 | Shinsozai Sogo Kenkyusho Kk | Gefüllter und abgedichteter, unabhängiger Mischbehälter. |
| US5209347A (en) * | 1990-12-05 | 1993-05-11 | Clintec Nutrition Company | Internal tear seal dual bag |
| JPH07300161A (ja) * | 1994-04-28 | 1995-11-14 | Kanae:Kk | 複数の収納部を有する包装体及び包装体の製造方法 |
| US5660273A (en) * | 1994-07-13 | 1997-08-26 | Centrix, Inc. | Single patient dose medicament dispenser with applicator |
| FR2733248B1 (fr) | 1995-04-20 | 1997-06-13 | Atochem Elf Sa | Composition de nettoyage a froid a base d'alcanes ou de cycloalcanes et d'un compose organique comprenant une fonction oxygenee |
| JPH10120040A (ja) | 1996-10-16 | 1998-05-12 | Toshiaki Endo | 2液反応型接着剤の包装方法 |
| DE29714246U1 (de) * | 1997-08-08 | 1998-12-10 | THERA Patent GmbH & Co. KG Gesellschaft für industrielle Schutzrechte, 82229 Seefeld | Vorrichtung zum Lagern und Auftragen einer fließfähigen Substanz |
| JPH11292154A (ja) | 1998-04-06 | 1999-10-26 | Senju Pharmaceut Co Ltd | 複数材料混合用容器 |
| GB9817578D0 (en) * | 1998-08-12 | 1998-10-07 | Cambridge Consultants | Pack |
| DE19962436B4 (de) * | 1999-12-22 | 2005-05-25 | 3M Espe Ag | Verfahren zum Ausbringen einer fließfähigen Substanz aus einer Verpackung |
-
2000
- 2000-11-13 DE DE10056212A patent/DE10056212B4/de not_active Expired - Fee Related
-
2001
- 2001-11-07 CA CA002422640A patent/CA2422640C/fr not_active Expired - Fee Related
- 2001-11-07 EP EP01993384A patent/EP1334047B1/fr not_active Expired - Lifetime
- 2001-11-07 AT AT01993384T patent/ATE304978T1/de not_active IP Right Cessation
- 2001-11-07 AU AU2181802A patent/AU2181802A/xx active Pending
- 2001-11-07 JP JP2002541016A patent/JP3801988B2/ja not_active Expired - Fee Related
- 2001-11-07 DE DE50107518T patent/DE50107518D1/de not_active Expired - Lifetime
- 2001-11-07 AU AU2002221818A patent/AU2002221818B2/en not_active Ceased
- 2001-11-07 US US10/416,544 patent/US7097075B2/en not_active Expired - Lifetime
- 2001-11-07 WO PCT/EP2001/012865 patent/WO2002038468A1/fr not_active Ceased
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USD1106454S1 (en) | 2023-06-14 | 2025-12-16 | Solventum Intellectual Properties Company | Dental material applicator with partitioned packaging |
Also Published As
| Publication number | Publication date |
|---|---|
| US7097075B2 (en) | 2006-08-29 |
| DE50107518D1 (de) | 2005-10-27 |
| DE10056212B4 (de) | 2005-08-18 |
| AU2002221818B2 (en) | 2006-09-14 |
| WO2002038468A1 (fr) | 2002-05-16 |
| US20040065679A1 (en) | 2004-04-08 |
| CA2422640A1 (fr) | 2003-03-13 |
| ATE304978T1 (de) | 2005-10-15 |
| DE10056212A1 (de) | 2002-05-23 |
| CA2422640C (fr) | 2009-10-20 |
| JP3801988B2 (ja) | 2006-07-26 |
| EP1334047A1 (fr) | 2003-08-13 |
| JP2004513040A (ja) | 2004-04-30 |
| AU2181802A (en) | 2002-05-21 |
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