EP1317247A1 - Traitement cosmetique de la peau et/ou des cheveux - Google Patents
Traitement cosmetique de la peau et/ou des cheveuxInfo
- Publication number
- EP1317247A1 EP1317247A1 EP00963378A EP00963378A EP1317247A1 EP 1317247 A1 EP1317247 A1 EP 1317247A1 EP 00963378 A EP00963378 A EP 00963378A EP 00963378 A EP00963378 A EP 00963378A EP 1317247 A1 EP1317247 A1 EP 1317247A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- composition
- cosmetic
- phase
- biologically active
- enzyme
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
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- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- BFZNCPXNOGIELB-UHFFFAOYSA-N propan-2-yl 10-[5,6-dihexyl-2-(8-oxo-8-propan-2-yloxyoctyl)cyclohex-3-en-1-yl]dec-9-enoate Chemical compound CCCCCCC1C=CC(CCCCCCCC(=O)OC(C)C)C(C=CCCCCCCCC(=O)OC(C)C)C1CCCCCC BFZNCPXNOGIELB-UHFFFAOYSA-N 0.000 description 1
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- CRPCXAMJWCDHFM-UHFFFAOYSA-M sodium;5-oxopyrrolidine-2-carboxylate Chemical compound [Na+].[O-]C(=O)C1CCC(=O)N1 CRPCXAMJWCDHFM-UHFFFAOYSA-M 0.000 description 1
- 238000000638 solvent extraction Methods 0.000 description 1
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- 238000010561 standard procedure Methods 0.000 description 1
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- 150000008163 sugars Chemical class 0.000 description 1
- 108010001535 sulfhydryl oxidase Proteins 0.000 description 1
- DIORMHZUUKOISG-UHFFFAOYSA-N sulfoformic acid Chemical compound OC(=O)S(O)(=O)=O DIORMHZUUKOISG-UHFFFAOYSA-N 0.000 description 1
- 230000037072 sun protection Effects 0.000 description 1
- 235000020238 sunflower seed Nutrition 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- DCWZELMIUJYGMS-UHFFFAOYSA-N tetradecyl 2,2-dimethylpropanoate Chemical compound CCCCCCCCCCCCCCOC(=O)C(C)(C)C DCWZELMIUJYGMS-UHFFFAOYSA-N 0.000 description 1
- YRZGMTHQPGNLEK-UHFFFAOYSA-N tetradecyl propionate Chemical compound CCCCCCCCCCCCCCOC(=O)CC YRZGMTHQPGNLEK-UHFFFAOYSA-N 0.000 description 1
- 229960004559 theobromine Drugs 0.000 description 1
- 125000003944 tolyl group Chemical group 0.000 description 1
- 239000012049 topical pharmaceutical composition Substances 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000041 toxicology testing Toxicity 0.000 description 1
- CRDAMVZIKSXKFV-UHFFFAOYSA-N trans-Farnesol Natural products CC(C)=CCCC(C)=CCCC(C)=CCO CRDAMVZIKSXKFV-UHFFFAOYSA-N 0.000 description 1
- 102000003601 transglutaminase Human genes 0.000 description 1
- HTJNEBVCZXHBNJ-XCTPRCOBSA-H trimagnesium;(2r)-2-[(1s)-1,2-dihydroxyethyl]-3,4-dihydroxy-2h-furan-5-one;diphosphate Chemical compound [Mg+2].[Mg+2].[Mg+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.OC[C@H](O)[C@H]1OC(=O)C(O)=C1O HTJNEBVCZXHBNJ-XCTPRCOBSA-H 0.000 description 1
- LINXHFKHZLOLEI-UHFFFAOYSA-N trimethyl-[phenyl-bis(trimethylsilyloxy)silyl]oxysilane Chemical compound C[Si](C)(C)O[Si](O[Si](C)(C)C)(O[Si](C)(C)C)C1=CC=CC=C1 LINXHFKHZLOLEI-UHFFFAOYSA-N 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- UEVAMYPIMMOEFW-UHFFFAOYSA-N trolamine salicylate Chemical compound OCCN(CCO)CCO.OC(=O)C1=CC=CC=C1O UEVAMYPIMMOEFW-UHFFFAOYSA-N 0.000 description 1
- 235000013799 ultramarine blue Nutrition 0.000 description 1
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- 235000019168 vitamin K Nutrition 0.000 description 1
- 239000011712 vitamin K Substances 0.000 description 1
- 150000003721 vitamin K derivatives Chemical class 0.000 description 1
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- 239000011800 void material Substances 0.000 description 1
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- 230000002087 whitening effect Effects 0.000 description 1
- 239000000811 xylitol Substances 0.000 description 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
- 235000010447 xylitol Nutrition 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/88—Two- or multipart kits
- A61K2800/884—Sequential application
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Definitions
- the cosmetic method of the present invention comprises administering, through phase one of the treatment regimen cycle, one or more doses of a cosmetic composition comprising a biologically active enzyme, wherein the biologically active enzyme is stably formulated.
- compositions useful herein comprise one or more enzymes selected from lipases, phospholipases, glycosidases, lactoperoxidases and cellulases, and mixtures thereof.
- Cosmetic compositions for use in phase one of the treatment method comprise from about 0.0001% to about 10%, more preferably from about 0.001% to about 5%, even more preferably from about 0.005% to about 1%, and most preferably from about 0.005% to about 0.5%, by weight, of the biologically active enzyme.
- Protease enzymes are the highly preferred biologically active compound for use herein.
- protease enzymes are classified under the Enzyme Classification number E.C. 3.4 (Carboxylic Ester Hydrolases) in accordance with the Recommendations (1992) ofthe International Union of Biochemistry and Molecular Biology (TUBMB).
- Useful proteases are also described in PCT publications: WO 95/30010 published November 9, 1995 by The Procter & Gamble Company; WO 95/30011 published November 9, 1995 by The Procter & Gamble Company; WO 95/29979 published November 9, 1995 by The Procter & Gamble Company.
- Preferred protease enzymes for use herein are subtilisin, chymotrypsin and elastase-type protease enzymes.
- the type of carrier ultilised in the present invention depends on the type of product form desired for the composition.
- the topical compositions useful in the subject invention may be made into a wide variety of product forms such as are known in the art. These include, but are not limited to, lotions, creams, gels, sticks, ointments, pastes and mousses. These product forms may comprise several types of carriers including, but not limited to, solutions, emulsions, and gels.
- Preferred carriers comprise an emulsion comprising a hydrophilic phase, especially an aqueous phase, and a hydrophobic phase e.g., a lipid, oil or oily material.
- a hydrophilic phase will be dispersed in the hydrophobic phase, or vice versa, to form respectively hydrophilic or hydrophobic dispersed and continuous phases, depending on the composition ingredients.
- the term "dispersed phase” is a term well-known to one skilled in the art which means that the phase exists as small particles or droplets that are suspended in and surrounded by a continuous phase.
- the dispersed phase is also known as the internal or discontinuous phase.
- Preferred humectants include, but are not limited to, compounds selected from urea, D or DL panthenol, calcium pantothenate, royal jelly, panthetine, pantotheine, panthenyl ethyl ether, pangamic acid, pyridoxin, pantoyl lactose Vitamin B complex, hexane - 1, 2, 6, - triol, guanidine or its derivatives.
- Highly preferred humectants are urea, panthenol and mixtures thereof. The above listed compounds may be incorporated singly or in combination.
- compositions herein preferably contain an emulsifier and/or surfactant, generally to help disperse and suspend the disperse phase within the continuous aqueous phase.
- a surfactant may also be useful if the product is intended for skin cleansing.
- emulsifiers will be referred to under the term 'surfactants', thus 'surfactant(s)' will be used to refer to surface active agents whether used as emulsifiers or for other surfactant purposes such as skin cleansing.
- Known or conventional surfactants can be used in the composition, provided that the selected agent is chemically and physically compatible with essential components of the composition, and provides the desired characteristics. Suitable surfactants include non-silicone derived materials, and mixtures thereof. All surfactants discussed in application WO 00/24372 should be considered as suitable for use in the present invention.
- An emulsifier for use herein is most preferably a fatty acid ester blend based on a mixture of sorbitan fatty acid ester and sucrose fatty acid ester, especially a blend of sorbiton stearate and sucrose cocoate.
- This is commercially available from ICI under the trade name Arlatone 2121.
- Even further suitable examples include a mixture of cetearyl alcohols, cetearyl glucosides such as those available under the trade name Montanov 68 from Seppic and Emulgade PL68/50 available from Henkel..
- compositions of the invention can also contain from about 0.01% to about 10%, preferably from about 0.1% to about 5% of a panthenol moisturizer.
- the panthenol moisturizer can be selected from D-panthenol ([R]-2,4-dihydroxy-N-[3-hydroxypropyl)]- 3,3-dimethylbutamide), DL-panthenol, calcium pantothenate, royal jelly, panthetine, pantotheine, panthenyl ethyl ether, pangamic acid, pyridoxin, and pantoyl lactose.
- a safe and effective amount of an anti-inflammatory agent may be added to the compositions of the subject invention, preferably from about 0.1 %> to about 5%>, more preferably from about 0.1 %> to about 2%, of the composition.
- the anti-inflammatory agent enhances the skin appearance benefits of the present invention, e.g., such agents contribute to a more uniform and acceptable skin tone or colour.
- the exact amount of anti-inflammatory agent to be used in the compositions will depend on the particular anti- inflammatory agent utilised since such agents vary widely in potency.
- compositions preferably comprise from about 0.1% to about 10%, more preferably from about 0.2%o to about 5%>, also preferably from about 0.5%> to about 2%>, of a skin lightening agent.
- Suitable skin lightening agents include those known in the art, including kojic acid, arbutin, ascorbic acid and derivatives thereof, e.g., magnesium ascorbyl phosphate.
- Further skin lightening agents suitable for use herein also include those described in WO 95/34280 and WO 95/23780; each incorporated herein by reference.
- the dispensing system simultaneously dispenses the biologically active composition and the placebo composition together, in a highly preferred embodiment that this occurs through a single nozzle, and that during phase two the dispensing system dispenses only the placebo composition.
- the single dispensing system can be adapted to comprise enough material such that it is able to alternate between phase one and phase two of the treatment method for a period of one or more different treatment cycles.
- the single dispensing system comprises enough material such that at the end of phase one no further cosmetic composition comprising biologically active material remains and that at the end of phase two no further placebo composition remains.
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
Abstract
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2000/024979 WO2002022099A1 (fr) | 2000-09-13 | 2000-09-13 | Traitement cosmetique de la peau et/ou des cheveux |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EP1317247A1 true EP1317247A1 (fr) | 2003-06-11 |
Family
ID=21741766
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP00963378A Withdrawn EP1317247A1 (fr) | 2000-09-13 | 2000-09-13 | Traitement cosmetique de la peau et/ou des cheveux |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1317247A1 (fr) |
| JP (1) | JP2004509861A (fr) |
| CN (1) | CN1468087A (fr) |
| AU (1) | AU2000274801A1 (fr) |
| MX (1) | MXPA03002166A (fr) |
| WO (1) | WO2002022099A1 (fr) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090017080A1 (en) * | 2007-03-15 | 2009-01-15 | Paul Robert Tanner | Personal care kit having skin care compositions with a readily perceptible difference |
| FR2937512B1 (fr) * | 2008-10-23 | 2012-11-16 | Oreal | Systeme cosmetique comportant un systeme de reglage d'une caracteristique d'un produit en fonction d'une information d'horloge |
| CN104434728A (zh) * | 2014-11-15 | 2015-03-25 | 柳州市康小乐牛奶有限公司 | 一种马奶护手霜 |
| US9956151B2 (en) * | 2015-03-05 | 2018-05-01 | Avon Products, Inc. | Methods for treating skin |
| US10076479B1 (en) | 2018-05-08 | 2018-09-18 | Avon Products, Inc. | Methods for treating skin |
| CN108272823A (zh) * | 2018-01-24 | 2018-07-13 | 北京臻溪谷医学研究中心(有限合伙) | 一种胎盘亚全能干细胞与间充质干细胞混合培养提取物的修复制剂及其制备方法 |
| WO2022020332A1 (fr) | 2020-07-21 | 2022-01-27 | Chembeau LLC | Formulations cosmétiques à base de diester et leurs utilisations |
| CN115317399A (zh) * | 2022-07-07 | 2022-11-11 | 湖北真福医药有限公司 | 一种抗衰老组合物及其制备方法和应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK149832C (da) * | 1981-07-17 | 1987-05-18 | Riemann Claus | Antiperspirantpraeparat bestaaende af to komponenter |
| ATE114473T1 (de) * | 1984-04-30 | 1994-12-15 | Procter & Gamble | Ausrüstung für die verwendung bei der behandlung von osteoporose. |
| GB9207280D0 (en) * | 1992-04-02 | 1992-05-13 | Unilever Plc | Skin care method and composition |
| EP0817613B1 (fr) * | 1996-01-31 | 2005-03-30 | Cosmoferm B.V. | Utilisation de compositions comprenant des enzymes stabilises |
| JP2002515903A (ja) * | 1997-02-12 | 2002-05-28 | ジョンソン・アンド・ジョンソン・コンシューマー・カンパニーズ・インコーポレイテッド | セリンプロテアーゼと局所レチノイドの組成物 |
| IE990935A1 (en) * | 1999-11-08 | 2002-04-03 | Procter & Gamble | Cosmetic Compositions |
-
2000
- 2000-09-13 EP EP00963378A patent/EP1317247A1/fr not_active Withdrawn
- 2000-09-13 AU AU2000274801A patent/AU2000274801A1/en not_active Abandoned
- 2000-09-13 CN CNA008198918A patent/CN1468087A/zh active Pending
- 2000-09-13 JP JP2002526351A patent/JP2004509861A/ja active Pending
- 2000-09-13 MX MXPA03002166A patent/MXPA03002166A/es unknown
- 2000-09-13 WO PCT/US2000/024979 patent/WO2002022099A1/fr not_active Ceased
Non-Patent Citations (1)
| Title |
|---|
| See references of WO0222099A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1468087A (zh) | 2004-01-14 |
| JP2004509861A (ja) | 2004-04-02 |
| WO2002022099A1 (fr) | 2002-03-21 |
| AU2000274801A1 (en) | 2002-03-26 |
| MXPA03002166A (es) | 2003-07-24 |
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