EP1361866A4 - Emulsions as solid dosage forms for oral administration - Google Patents

Emulsions as solid dosage forms for oral administration

Info

Publication number: EP1361866A4
Authority: EP; European Patent Office
Prior art keywords: emulsions; dosage forms; oral administration; solid dosage; solid
Prior art date: 2001-02-23
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Ceased

Application number

EP20010913012

Other languages

German (de)

French (fr)

Other versions

EP1361866A1 (en

Inventor

S Indiran Pather

Sangeeta V Gupte

Rajendra K Khankari

Jon Hontz

Ramya Kumbale

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Cima Labs Inc

Original Assignee

Cima Labs Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-02-23

Filing date

2001-02-23

Publication date

2007-10-17

2001-02-23 Application filed by Cima Labs Inc filed Critical Cima Labs Inc

2003-11-19 Publication of EP1361866A1 publication Critical patent/EP1361866A1/en

2007-10-17 Publication of EP1361866A4 publication Critical patent/EP1361866A4/en

Status Ceased legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
- A61K9/025—Suppositories; Bougies; Bases therefor; Ovules characterised by shape or structure, e.g. hollow layered, coated
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Inorganic Chemistry (AREA)
Medicinal Preparation (AREA)

EP20010913012 2001-02-23 2001-02-23 Emulsions as solid dosage forms for oral administration Ceased EP1361866A4 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/US2001/005978 WO2002083102A1 (en)	2001-02-23	2001-02-23	Emulsions as solid dosage forms for oral administration

Publications (2)

Publication Number	Publication Date
EP1361866A1 EP1361866A1 (en)	2003-11-19
EP1361866A4 true EP1361866A4 (en)	2007-10-17

Family

ID=21742362

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP20010913012 Ceased EP1361866A4 (en)	2001-02-23	2001-02-23	Emulsions as solid dosage forms for oral administration

Country Status (5)

Country	Link
EP (1)	EP1361866A4 (en)
JP (1)	JP5684440B2 (en)
AU (1)	AU2001241730B2 (en)
CA (1)	CA2437762C (en)
WO (1)	WO2002083102A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7815937B2 (en)	1998-10-27	2010-10-19	Biovail Laboratories International Srl	Quick dissolve compositions and tablets based thereon
FR2851918B1 (en) *	2003-03-06	2006-06-16		IMPREGNATED POWDER ENHANCING BIOAVAILABILITY AND / OR SOLUBILITY AND METHOD OF MANUFACTURE
JP5661630B2 (en) *	2008-09-09	2015-01-28	シマラブスインク．	Weak ionic compound dosage forms
US20120213855A1 (en) *	2011-02-17	2012-08-23	Cima Labs Inc.	Dosage forms for weakly ionizable compounds
ES2395801B1 (en) *	2011-06-23	2014-06-06	María Carmen PARDINA PALLEJÀ	"PENTOXIFILINA BY TRANSVAGINAL ROUTE FOR THE TREATMENT OF INFERTILITY"

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1468815A (en) *	1973-10-18	1977-03-30	Vymatt Sa	Pharmaceutical compositions
WO1997047290A1 (en) *	1996-06-10	1997-12-18	Spiridon Spireas	Liquisolid systems and methods of preparing same
WO2000009093A1 (en) *	1998-08-13	2000-02-24	Cima Labs Inc.	Microemulsions as solid dosage forms for oral administration

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH586568A5 (en) *	1972-04-10	1977-04-15	Hoffmann La Roche
JPS58213073A (en) *	1982-06-07	1983-12-10	Masatoshi Yamada	Solidification of oily substance
FR2561916B1 (en) *	1984-03-30	1987-12-11	Lafon Labor	GALENIC FORM FOR ORAL ADMINISTRATION AND METHOD FOR PREPARING IT BY LYOPHILIZATION OF AN OIL-TO-WATER EMISSION
JP4027535B2 (en) *	1998-05-26	2007-12-26	エーザイ・アール・アンド・ディー・マネジメント株式会社	Powder containing fat-soluble drug
JP2000016934A (en) *	1998-06-30	2000-01-18	Eisai Co Ltd	Tablets including teprenone
US5997905A (en) *	1998-09-04	1999-12-07	Mcneil-Ppc	Preparation of pharmaceutically active particles

2001
- 2001-02-23 WO PCT/US2001/005978 patent/WO2002083102A1/en not_active Ceased
- 2001-02-23 EP EP20010913012 patent/EP1361866A4/en not_active Ceased
- 2001-02-23 JP JP2002580906A patent/JP5684440B2/en not_active Expired - Fee Related
- 2001-02-23 AU AU2001241730A patent/AU2001241730B2/en not_active Ceased
- 2001-02-23 CA CA2437762A patent/CA2437762C/en not_active Expired - Fee Related

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1468815A (en) *	1973-10-18	1977-03-30	Vymatt Sa	Pharmaceutical compositions
WO1997047290A1 (en) *	1996-06-10	1997-12-18	Spiridon Spireas	Liquisolid systems and methods of preparing same
WO2000009093A1 (en) *	1998-08-13	2000-02-24	Cima Labs Inc.	Microemulsions as solid dosage forms for oral administration

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO02083102A1 *

Also Published As

Publication number	Publication date
AU2001241730B2 (en)	2007-03-15
WO2002083102A1 (en)	2002-10-24
EP1361866A1 (en)	2003-11-19
CA2437762C (en)	2010-08-10
CA2437762A1 (en)	2002-10-24
JP5684440B2 (en)	2015-03-11
JP2004524370A (en)	2004-08-12

Publication	Publication Date	Title
PL356358A1 (en)	2003-04-07	Solid dosage form of someticone for oral administration
GB0117618D0 (en)	2001-09-12	Pharmaceutical dosage form
EG23943A (en)	2008-01-22	Flash-melt oral dosage formulation
PL364621A1 (en)	2004-12-13	Nicotine-containing oral dosage form
GB0117619D0 (en)	2001-09-12	Pharmaceutical dosage form
MXPA03006476A (en)	2003-09-22	Pharmaceutical dosage forms of epothilones for oral administration.
AU2002301259A1 (en)	2003-06-12	Simethicone solid oral dosage form
IL166286A0 (en)	2006-01-15	Multicomponent pharmaceutical dosage form
HUP0400850A3 (en)	2010-10-28	Oral pharmaceutical compositions
PL377495A1 (en)	2006-02-06	Solid drug for oral use
GB0101227D0 (en)	2001-02-28	Pharmaceutical compounds
HUP0500638A3 (en)	2008-04-28	Flashmelt oral dosage formulation
GB0101225D0 (en)	2001-02-28	Pharmaceutical compounds
IL162510A0 (en)	2005-11-20	Pharmaceutical suspension for oral administration
EP1361866A4 (en)	2007-10-17	Emulsions as solid dosage forms for oral administration
IL172890A0 (en)	2006-06-11	Saquinavir mesylate oral dosage form
HUP0401599A3 (en)	2007-03-28	Extended release oral dosage form
EP1357898A4 (en)	2005-07-13	Improved controlled release oral dosage form
IL174009A0 (en)	2006-08-01	Melt-formulated, multi-particulate oral dosage form
HUP0200253A3 (en)	2003-04-28	Pharmaceutical compositions for combination therapy
AU2002348105A1 (en)	2003-05-12	Oral dosage forms for improving the bioavailability of therapeutic agents
AU2002342940A8 (en)	2003-06-10	New pharmaceutical compounds
ZA200204905B (en)	2003-04-30	Improved pharmaceutical dental formulations.
PL373799A1 (en)	2005-09-19	Flashmelt oral dosage formulation
PL341178A1 (en)	2002-01-02	Oral pharmaceutical dosage forms

Legal Events

Date	Code	Title	Description
2003-10-03	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2003-11-19	17P	Request for examination filed	Effective date: 20030821
2003-11-19	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
2003-11-19	AX	Request for extension of the european patent	Extension state: AL LT LV MK RO SI
2007-10-17	A4	Supplementary search report drawn up and despatched	Effective date: 20070918
2009-05-27	17Q	First examination report despatched	Effective date: 20090423
2015-10-22	REG	Reference to a national code	Ref country code: DE Ref legal event code: R003
2016-05-06	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED
2016-06-08	18R	Application refused	Effective date: 20151022