EP1233671A4 - Zusammensetzungen und verfahren zur arzneistoffabgabe unter verwendung von amphiphilen bindungsmolekülen - Google Patents

Zusammensetzungen und verfahren zur arzneistoffabgabe unter verwendung von amphiphilen bindungsmolekülen

Info

Publication number: EP1233671A4
Authority: EP; European Patent Office
Prior art keywords: compositions; methods; drug delivery; binding molecules; amphiphile
Prior art date: 1999-11-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP00982310A

Other languages

English (en)

French (fr)

Other versions

EP1233671A1 (de

Inventor

Jon A Wolff

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Arrowhead Madison Inc

Original Assignee

Mirus Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-11-29

Filing date

2000-11-29

Publication date

2005-11-02

2000-11-29 Application filed by Mirus Corp filed Critical Mirus Corp

2002-08-28 Publication of EP1233671A1 publication Critical patent/EP1233671A1/de

2005-11-02 Publication of EP1233671A4 publication Critical patent/EP1233671A4/de

Status Withdrawn legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
- A61K48/0025—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid
- A61K48/0041—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid the non-active part being polymeric
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
Biotechnology (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Biochemistry (AREA)
Public Health (AREA)
Biophysics (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Veterinary Medicine (AREA)
Microbiology (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

EP00982310A 1999-11-29 2000-11-29 Zusammensetzungen und verfahren zur arzneistoffabgabe unter verwendung von amphiphilen bindungsmolekülen Withdrawn EP1233671A4 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US16783699P	1999-11-29	1999-11-29
US167836P		1999-11-29
PCT/US2000/032612 WO2001037665A1 (en)	1999-11-29	2000-11-29	Compositions and methods for drug delivery using amphiphile binding molecules

Publications (2)

Publication Number	Publication Date
EP1233671A1 EP1233671A1 (de)	2002-08-28
EP1233671A4 true EP1233671A4 (de)	2005-11-02

Family

ID=22609038

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP00982310A Withdrawn EP1233671A4 (de)	1999-11-29	2000-11-29	Zusammensetzungen und verfahren zur arzneistoffabgabe unter verwendung von amphiphilen bindungsmolekülen

Country Status (2)

Country	Link
EP (1)	EP1233671A4 (de)
WO (1)	WO2001037665A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6509323B1 (en)	1998-07-01	2003-01-21	California Institute Of Technology	Linear cyclodextrin copolymers
US7091192B1 (en)	1998-07-01	2006-08-15	California Institute Of Technology	Linear cyclodextrin copolymers
US7375096B1 (en)	1998-12-04	2008-05-20	California Institute Of Technology	Method of preparing a supramolecular complex containing a therapeutic agent and a multi-dimensional polymer network
TWI321054B (en)	2000-12-19	2010-03-01	California Inst Of Techn	Compositions containing inclusion complexes
EP2325193A3 (de) *	2001-11-02	2012-05-02	Insert Therapeutics, Inc.	Verfahren und Zusammensetzungen zur therapeutischen Verwendung von RNA-Interferenz
EP1507874A4 (de) *	2002-05-28	2006-06-28	Mirus Bio Corp	Zusammensetzungen und verfahren zur hemmung der genexpression mit polynukleotiden
FR2842106B1 (fr)	2002-07-11	2006-07-14	Centre Nat Rech Scient	Dispersions aqueuses de particules nanometriques ou micrometriques pour l'encapsulation de composes chimiques
BR122012021252B8 (pt)	2002-09-06	2021-05-25	Cerulean Pharma Inc	polímeros à base de ciclodextrina para o fornecimento de agentes terapêuticos ligados a eles por covalência
US8357377B2 (en)	2002-10-09	2013-01-22	Suzie Hwang Pun	Cyclodextrin-based materials, compositions and uses related thereto
US20080176958A1 (en)	2007-01-24	2008-07-24	Insert Therapeutics, Inc.	Cyclodextrin-based polymers for therapeutics delivery
EP2438908A1 (de)	2010-10-11	2012-04-11	Vectum Pharma, S.L.	Verankerungszusammensetzungen für topische Anwendungen
US20140094432A1 (en)	2012-10-02	2014-04-03	Cerulean Pharma Inc.	Methods and systems for polymer precipitation and generation of particles

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2000001418A1 (en) *	1998-07-02	2000-01-13	Genzyme Corporation	Transgene expression in polarized cells
WO2001015755A2 (en) *	1999-09-01	2001-03-08	Genecure Pte Ltd	Methods and compositions for delivery of pharmaceutical agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5283185A (en) *	1991-08-28	1994-02-01	University Of Tennessee Research Corporation	Method for delivering nucleic acids into cells
US5650096A (en) *	1994-12-09	1997-07-22	Genzyme Corporation	Cationic amphiphiles for intracellular delivery of therapeutic molecules
US5965434A (en) *	1994-12-29	1999-10-12	Wolff; Jon A.	Amphipathic PH sensitive compounds and delivery systems for delivering biologically active compounds
US5942634A (en) *	1997-05-09	1999-08-24	Genzyme Corporation	Cationic amphiphiles for cell transfections

2000
- 2000-11-29 EP EP00982310A patent/EP1233671A4/de not_active Withdrawn
- 2000-11-29 WO PCT/US2000/032612 patent/WO2001037665A1/en not_active Ceased

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2000001418A1 (en) *	1998-07-02	2000-01-13	Genzyme Corporation	Transgene expression in polarized cells
WO2001015755A2 (en) *	1999-09-01	2001-03-08	Genecure Pte Ltd	Methods and compositions for delivery of pharmaceutical agents

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CROYLE MA ET AL: "Beta cyclodextrins enhance gene delivery to the intestine", PROCEEDINGS OF THE INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE BIOACTIVE MATERIALS, vol. 24, 1997, pages 675 - 676, XP002122911, ISSN: 1022-0178 *
FREEMAN D J ET AL: "THE INFLUENCE OF SODIUM GLYCOCHOLATE AND OTHER ADDITIVES ON THE IN VIVO TRANSFECTION OF PLASMID DNA IN THE LUNGS", PHARMACOLOGICAL RESEARCH, ACADEMIC PRESS, LONDON, GB, vol. 13, no. 2, 1 February 1996 (1996-02-01), pages 202 - 209, XP000646438, ISSN: 1043-6618 *
HABUS I ET AL: "SYNTHESIS, HYBRIDIZATION PROPERTIES, NUCLEASE STABILITY, AND ADAMANTANE CONJUGATES. CELLULAR UPTAKE OF THE OLIGONUCLEOTIDE-AMINO- CYCLODEXTRINS AND", BIOCONJUGATE CHEMISTRY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, US, vol. 6, no. 4, 1 July 1995 (1995-07-01), pages 327 - 331, XP000517222, ISSN: 1043-1802 *
See also references of WO0137665A1 *

Also Published As

Publication number	Publication date
WO2001037665A1 (en)	2001-05-31
EP1233671A1 (de)	2002-08-28

Publication	Publication Date	Title
TWI367096B (en)	2012-07-01	Vitamin-receptor binding drug delivery conjugates and pharmaceutical compositions
AU3692001A (en)	2001-09-03	Compositions and methods for enhancing drug delivery across biological membranesand tissues
AU2001235009A1 (en)	2001-11-01	Drug delivery apparatus
IL138990A0 (en)	2001-11-25	Matrices for drug delivery and methods for making and using the same
HUP0203588A3 (en)	2005-01-28	Analgesic pharmaceutical compositions and their use
EP1367995A4 (de)	2007-08-01	Zusammensetzungen und verfahren zur verbesserung der arzneimittelabgabe über und in das epithelgewebe
IL144325A0 (en)	2002-05-23	Compositions and methods for mucosal delivery
AU2001232049A1 (en)	2001-11-01	Improvements in and relating to controlling drug delivery apparatus
PL351387A1 (en)	2003-04-07	Pharmaceutical composition
HUP0204372A3 (en)	2004-06-28	Pharmaceutical compositions providing enhanced drug concentrations
EP1239831A4 (de)	2009-07-22	Verbesserte pharmazeutische zusammensetzungen für schwerlösliche arzneistoffe
AU6275601A (en)	2001-11-26	Stable polymeric micelle-type drug composition and method for the preparation thereof
IL135886A0 (en)	2001-05-20	Topical compositions for nsai drug delivery
AU5326100A (en)	2000-12-28	Pharmaceutical compositions and methods for use
GB2355252B (en)	2002-01-23	Improvements in drug delivery devices
HUP0302130A3 (en)	2005-06-28	Combination pharmaceutical compositions and process for their preparation
IL151910A0 (en)	2003-04-10	Compositions for drug delivery
EP1233671A4 (de)	2005-11-02	Zusammensetzungen und verfahren zur arzneistoffabgabe unter verwendung von amphiphilen bindungsmolekülen
HUP0200468A3 (en)	2002-12-28	Resorcinol derivatives and pharmaceutical compositions containing them
AU2001238485A1 (en)	2001-08-27	Methods and compositions for gene delivery
IL153487A0 (en)	2003-07-06	Pharmaceutical compositions and methods for use
EP1173192A4 (de)	2002-05-02	Verfahren und zusammensetzungen für eine gezielte verabreichung von medikamenten
AU3926000A (en)	2000-10-23	Methods and compositions for drug delivery
IL153897A0 (en)	2003-07-31	Pharmaceutical compositions and methods for use
AU2002308649A1 (en)	2002-11-18	Compositions and methods for enhancing drug delivery

Legal Events

Date	Code	Title	Description
2002-07-13	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2002-08-28	17P	Request for examination filed	Effective date: 20020612
2002-08-28	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
2005-11-02	A4	Supplementary search report drawn up and despatched	Effective date: 20050919
2005-11-02	RIC1	Information provided on ipc code assigned before grant	Ipc: 7A 61K 48/00 A Ipc: 7C 12N 15/88 B
2006-06-09	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2006-07-12	18D	Application deemed to be withdrawn	Effective date: 20051202