EP1268526A4 - Molecules d'acide nucleique specifiques de la prostate ou des testicules, polypeptides, techniques de diagnostic, et traitement therapeutique - Google Patents
Molecules d'acide nucleique specifiques de la prostate ou des testicules, polypeptides, techniques de diagnostic, et traitement therapeutiqueInfo
- Publication number
- EP1268526A4 EP1268526A4 EP01922630A EP01922630A EP1268526A4 EP 1268526 A4 EP1268526 A4 EP 1268526A4 EP 01922630 A EP01922630 A EP 01922630A EP 01922630 A EP01922630 A EP 01922630A EP 1268526 A4 EP1268526 A4 EP 1268526A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- specific
- testis
- polypeptides
- diagnostic
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19192900P | 2000-03-24 | 2000-03-24 | |
| US191929P | 2000-03-24 | ||
| PCT/US2001/009410 WO2001072962A2 (fr) | 2000-03-24 | 2001-03-23 | Molecules d'acide nucleique specifiques de la prostate ou des testicules, polypeptides, techniques de diagnostic, et traitement therapeutique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP1268526A2 EP1268526A2 (fr) | 2003-01-02 |
| EP1268526A4 true EP1268526A4 (fr) | 2004-09-08 |
Family
ID=22707491
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP01922630A Withdrawn EP1268526A4 (fr) | 2000-03-24 | 2001-03-23 | Molecules d'acide nucleique specifiques de la prostate ou des testicules, polypeptides, techniques de diagnostic, et traitement therapeutique |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1268526A4 (fr) |
| JP (1) | JP2004521602A (fr) |
| AU (2) | AU2001249411B2 (fr) |
| CA (1) | CA2403637A1 (fr) |
| WO (1) | WO2001072962A2 (fr) |
Families Citing this family (96)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1086223T3 (da) | 1998-06-01 | 2009-11-30 | Agensys Inc | Nye serpentintransmembranantigener udtrykt i humane cancerformer og anvendelser deraf |
| US20040141975A1 (en) | 1998-06-01 | 2004-07-22 | Raitano Arthur B. | Nucleic acid and corresponding protein entitled 98P4B6 useful in treatment and detection of cancer |
| US20030149531A1 (en) | 2000-12-06 | 2003-08-07 | Hubert Rene S. | Serpentine transmembrane antigens expressed in human cancers and uses thereof |
| US20060052321A1 (en) | 2002-04-05 | 2006-03-09 | Raitano Arthur B | Nucleic acid and corresponding protein entitled 98P4B6 useful in treatment and detection of cancer |
| US20040048798A1 (en) * | 1999-06-01 | 2004-03-11 | Raitano Arthur B. | Nucleic acid and corresponding protein entitle 98P4B6 useful in treatment and detection of cancer |
| US6833438B1 (en) | 1999-06-01 | 2004-12-21 | Agensys, Inc. | Serpentine transmembrane antigens expressed in human cancers and uses thereof |
| EP1328151A4 (fr) * | 1999-04-29 | 2004-06-16 | Univ Tennessee Res Corp | Acides nucleiques isoles de la famille p-hyde, proteines p-hyde et procede pour induire la susceptibilite a l'induction de la mort cellulaire programmee pendant le cancer |
| US6835812B1 (en) | 1999-04-29 | 2004-12-28 | University Of Tennessee Research Corporation | Human p-Hyde proteins |
| US7611892B2 (en) | 2000-03-24 | 2009-11-03 | President And Fellows Of Harvard College | Prostate-specific or testis-specific nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods |
| WO2005114216A2 (fr) * | 2005-02-22 | 2005-12-01 | Biomedisinsk Innovasjon As | Molecules d'acides nucleiques stamp2, polypeptides, et procedes diagnostiques et therapeutiques |
| GB2379660A (en) * | 2001-01-30 | 2003-03-19 | Aeomica Inc | Human GTP-Rho binding protein 2 |
| EP1231216A3 (fr) * | 2001-01-30 | 2004-03-17 | Aeomica, Inc. | Protéine humaine qui se lie au gtp-rho |
| CA2459318C (fr) | 2001-09-06 | 2017-09-26 | Agensys, Inc. | Acide nucleique et proteine correspondante designes par steap-1 utiles dans le traitement et la detection du cancer |
| US7494646B2 (en) | 2001-09-06 | 2009-02-24 | Agensys, Inc. | Antibodies and molecules derived therefrom that bind to STEAP-1 proteins |
| JP2005534287A (ja) * | 2002-04-05 | 2005-11-17 | アジェンシス, インコーポレイテッド | 癌の処置および検出において有用な98p4b6との名称の核酸および対応するタンパク質 |
| JP5840351B2 (ja) * | 2002-09-06 | 2016-01-06 | アジェンシス,インコーポレイテッド | 癌の処置および検出において有用な98p4b6と称される、核酸および対応タンパク質 |
| BR122018071808B8 (pt) | 2003-11-06 | 2020-06-30 | Seattle Genetics Inc | conjugado |
| GB0326834D0 (en) * | 2003-11-18 | 2003-12-24 | Celltech R&D Ltd | A protein involved in lung cancer |
| TWI238677B (en) | 2003-12-25 | 2005-08-21 | Fujitsu Ltd | Organic EL element, organic EL display, process for fabricating organic EL element, and device for fabricating organic EL element |
| DK1742966T3 (da) | 2004-04-22 | 2014-02-03 | Agensys Inc | Antistoffer og molekyler afledt deraf som binder til STEAP-1 proteiner |
| BRPI0510883B8 (pt) | 2004-06-01 | 2021-05-25 | Genentech Inc | composto conjugado de droga e anticorpo, composição farmacêutica, método de fabricação de composto conjugado de droga e anticorpo e usos de uma formulação, de um conjugado de droga e anticorpo e um agente quimioterapêutico e de uma combinação |
| US20100111856A1 (en) | 2004-09-23 | 2010-05-06 | Herman Gill | Zirconium-radiolabeled, cysteine engineered antibody conjugates |
| CN101065151B (zh) | 2004-09-23 | 2014-12-10 | 健泰科生物技术公司 | 半胱氨酸改造的抗体和偶联物 |
| CA2667019C (fr) | 2006-10-27 | 2016-03-29 | Genentech, Inc. | Anticorps et immunoconjugues, et leurs utilisations |
| US8426673B2 (en) * | 2008-01-11 | 2013-04-23 | Astellas Pharma, Inc. | Pathological animal model for pelvic pain syndrome |
| US8470980B2 (en) | 2009-09-09 | 2013-06-25 | Centrose, Llc | Extracellular targeted drug conjugates |
| BR112012026213B1 (pt) | 2010-04-15 | 2021-12-28 | Medimmune Limited | Compostos de pirrolobenzodiazepinas, conjugado das mesmas, composição farmacêutica compreendendo o conjugado e uso do mesmo para o tratamento de uma doença proliferativa |
| WO2011156328A1 (fr) | 2010-06-08 | 2011-12-15 | Genentech, Inc. | Anticorps et conjugués modifiés par la cystéine |
| CN103313990B (zh) | 2010-11-17 | 2016-07-20 | 基因泰克公司 | 丙氨酰美登醇抗体偶联物 |
| US8679767B2 (en) | 2011-05-12 | 2014-03-25 | Genentech, Inc. | Multiple reaction monitoring LC-MS/MS method to detect therapeutic antibodies in animal samples using framework signature peptides |
| SG11201401406YA (en) | 2011-10-14 | 2014-05-29 | Spirogen Sarl | Pyrrolobenzodiazepines and conjugates thereof |
| WO2013130093A1 (fr) | 2012-03-02 | 2013-09-06 | Genentech, Inc. | Biomarqueurs pour un traitement à base de composés chimiothérapeutiques anti-tubuline |
| PT2906298T (pt) | 2012-10-12 | 2018-12-28 | Medimmune Ltd | Conjugados de pirrolobenzodiazepina-anticorpos |
| SMT201800346T1 (it) | 2012-10-12 | 2018-09-13 | Medimmune Ltd | Coniugati pirrolobenzodiazepina-anticorpo |
| WO2014057122A1 (fr) | 2012-10-12 | 2014-04-17 | Adc Therapeutics Sàrl | Conjugués anticorps anti-cd22 - pyrrolobenzodiazépine |
| WO2014057074A1 (fr) | 2012-10-12 | 2014-04-17 | Spirogen Sàrl | Pyrrolobenzodiazépines et leurs conjugués |
| SI2906253T1 (sl) | 2012-10-12 | 2018-11-30 | Adc Therapeutics Sa | Konjugati pirolobenzodiazepin-protitelo proti PSMA |
| EP2906250B1 (fr) | 2012-10-12 | 2018-05-30 | ADC Therapeutics SA | Conjugués pyrrolobenzodiazepine-anticorps anti-psma |
| US10695433B2 (en) | 2012-10-12 | 2020-06-30 | Medimmune Limited | Pyrrolobenzodiazepine-antibody conjugates |
| JP6307519B2 (ja) | 2012-12-21 | 2018-04-04 | メドイミューン・リミテッドMedImmune Limited | ピロロベンゾジアゼピンおよびその結合体 |
| CN110627797A (zh) | 2012-12-21 | 2019-12-31 | 麦迪穆有限责任公司 | 用于治疗增殖性和自身免疫疾病的非对称吡咯并苯并二氮杂卓二聚物 |
| AU2014230735B2 (en) | 2013-03-13 | 2018-03-15 | Medimmune Limited | Pyrrolobenzodiazepines and conjugates thereof |
| JP6340019B2 (ja) | 2013-03-13 | 2018-06-06 | メドイミューン・リミテッドMedImmune Limited | ピロロベンゾジアゼピン及びそのコンジュゲート |
| EP2968596B1 (fr) | 2013-03-13 | 2019-03-06 | Medimmune Limited | Pyrrolobenzodiazépines et leurs conjugués |
| US10442836B2 (en) | 2013-08-12 | 2019-10-15 | Genentech, Inc. | 1-(chloromethyl)-2,3-dihydro-1H-benzo[E]indole dimer antibody-drug conjugate compounds, and methods of use and treatment |
| GB201317982D0 (en) | 2013-10-11 | 2013-11-27 | Spirogen Sarl | Pyrrolobenzodiazepines and conjugates thereof |
| WO2015052535A1 (fr) | 2013-10-11 | 2015-04-16 | Spirogen Sàrl | Conjugués anticorps-pyrrolobenzodiazépine |
| US10010624B2 (en) | 2013-10-11 | 2018-07-03 | Medimmune Limited | Pyrrolobenzodiazepine-antibody conjugates |
| EP3054985B1 (fr) | 2013-10-11 | 2018-12-26 | Medimmune Limited | Conjugués anticorps-pyrrolobenzodiazépine |
| JP6980384B2 (ja) | 2013-12-16 | 2021-12-15 | ジェネンテック, インコーポレイテッド | 1−(クロロメチル)−2,3−ジヒドロ−1h−ベンゾ[e]インドール二量体抗体−薬物コンジュゲート化合物、並びに使用及び処置の方法 |
| RU2689388C1 (ru) | 2013-12-16 | 2019-05-28 | Дженентек, Инк. | Пептидомиметические соединения и их конъюгаты антител с лекарственными средствами |
| EA201691023A1 (ru) | 2013-12-16 | 2016-10-31 | Дженентек, Инк. | Пептидомиметические соединения и их конъюгаты антитела с лекарственным средством |
| US10188746B2 (en) | 2014-09-10 | 2019-01-29 | Medimmune Limited | Pyrrolobenzodiazepines and conjugates thereof |
| JP6622293B2 (ja) | 2014-09-12 | 2019-12-18 | ジェネンテック, インコーポレイテッド | アントラサイクリンジスルフィド中間体、抗体−薬物複合体、及び方法 |
| GB201416112D0 (en) | 2014-09-12 | 2014-10-29 | Medimmune Ltd | Pyrrolobenzodiazepines and conjugates thereof |
| MX2017003123A (es) | 2014-09-12 | 2017-05-12 | Genentech Inc | Anticuerpos y conjugados modificados geneticamente con cisteina. |
| AU2015317653A1 (en) | 2014-09-17 | 2017-04-06 | Genentech, Inc. | Pyrrolobenzodiazepines and antibody disulfide conjugates thereof |
| US10780096B2 (en) | 2014-11-25 | 2020-09-22 | Adc Therapeutics Sa | Pyrrolobenzodiazepine-antibody conjugates |
| JP6752204B2 (ja) | 2014-12-03 | 2020-09-09 | ジェネンテック, インコーポレイテッド | 四級アミン化合物及びその抗体−薬物コンジュゲート |
| GB201506411D0 (en) | 2015-04-15 | 2015-05-27 | Bergenbio As | Humanized anti-axl antibodies |
| GB201506402D0 (en) | 2015-04-15 | 2015-05-27 | Berkel Patricius H C Van And Howard Philip W | Site-specific antibody-drug conjugates |
| MA43345A (fr) | 2015-10-02 | 2018-08-08 | Hoffmann La Roche | Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation |
| MA43354A (fr) | 2015-10-16 | 2018-08-22 | Genentech Inc | Conjugués médicamenteux à pont disulfure encombré |
| MA45326A (fr) | 2015-10-20 | 2018-08-29 | Genentech Inc | Conjugués calichéamicine-anticorps-médicament et procédés d'utilisation |
| GB201601431D0 (en) | 2016-01-26 | 2016-03-09 | Medimmune Ltd | Pyrrolobenzodiazepines |
| GB201602359D0 (en) | 2016-02-10 | 2016-03-23 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
| GB201602356D0 (en) | 2016-02-10 | 2016-03-23 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
| US20170315132A1 (en) | 2016-03-25 | 2017-11-02 | Genentech, Inc. | Multiplexed total antibody and antibody-conjugated drug quantification assay |
| GB201607478D0 (en) | 2016-04-29 | 2016-06-15 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
| ES2858151T3 (es) | 2016-05-20 | 2021-09-29 | Hoffmann La Roche | Conjugados de PROTAC-anticuerpo y procedimientos de uso |
| US20170370906A1 (en) | 2016-05-27 | 2017-12-28 | Genentech, Inc. | Bioanalytical analysis of site-specific antibody drug conjugates |
| EP3464280B1 (fr) | 2016-06-06 | 2021-10-06 | F. Hoffmann-La Roche AG | Médicaments conjugués d'anticorps silvestrol et procédés d'utilisation |
| WO2018031662A1 (fr) | 2016-08-11 | 2018-02-15 | Genentech, Inc. | Promédicaments de pyrrolobenzodiazépine et conjugués d'anticorps de ceux-ci |
| CN110139674B (zh) | 2016-10-05 | 2023-05-16 | 豪夫迈·罗氏有限公司 | 制备抗体药物缀合物的方法 |
| GB201617466D0 (en) | 2016-10-14 | 2016-11-30 | Medimmune Ltd | Pyrrolobenzodiazepine conjugates |
| ES2871001T3 (es) | 2017-02-08 | 2021-10-28 | Adc Therapeutics Sa | Conjugados de pirrolobenzodiazepinas y anticuerpos |
| GB201702031D0 (en) | 2017-02-08 | 2017-03-22 | Medlmmune Ltd | Pyrrolobenzodiazepine-antibody conjugates |
| ES2955852T3 (es) | 2017-04-03 | 2023-12-07 | Hoffmann La Roche | Anticuerpos de unión a STEAP-1 |
| WO2018192944A1 (fr) | 2017-04-18 | 2018-10-25 | Medimmune Limited | Conjugués de pyrrolobenzodiazépine |
| CA3057748A1 (fr) | 2017-04-20 | 2018-10-25 | Adc Therapeutics Sa | Polytherapie avec un conjugue anticorps anti-axl-medicament |
| ES2988683T3 (es) | 2017-06-14 | 2024-11-21 | Adc Therapeutics Sa | Pautas posológicas para la administración de un CAF anti-CD19 |
| SG11202000358YA (en) | 2017-08-18 | 2020-02-27 | Medimmune Ltd | Pyrrolobenzodiazepine conjugates |
| KR20220156974A (ko) | 2017-09-20 | 2022-11-28 | 주식회사 피에이치파마 | 타일란스타틴 유사체 |
| GB201803342D0 (en) | 2018-03-01 | 2018-04-18 | Medimmune Ltd | Methods |
| GB201806022D0 (en) | 2018-04-12 | 2018-05-30 | Medimmune Ltd | Pyrrolobenzodiazepines and conjugates thereof |
| GB201814281D0 (en) | 2018-09-03 | 2018-10-17 | Femtogenix Ltd | Cytotoxic agents |
| EP3870235A1 (fr) | 2018-10-24 | 2021-09-01 | F. Hoffmann-La Roche AG | Inducteurs chimiques conjugués de dégradation et méthodes d'utilisation |
| EP3894427A1 (fr) | 2018-12-10 | 2021-10-20 | Genentech, Inc. | Peptides de photoréticulation pour conjugaison spécifique de site à des protéines contenant fc |
| GB201901197D0 (en) | 2019-01-29 | 2019-03-20 | Femtogenix Ltd | G-A Crosslinking cytotoxic agents |
| MX2021010477A (es) | 2019-03-15 | 2021-10-01 | Medimmune Ltd | Dimeros de azetidobenzodiazepina y conjugados que los comprenden para uso en el tratamiento de cancer. |
| GB2597532A (en) | 2020-07-28 | 2022-02-02 | Femtogenix Ltd | Cytotoxic compounds |
| WO2022078524A2 (fr) | 2021-11-03 | 2022-04-21 | Hangzhou Dac Biotech Co., Ltd. | Conjugaison spécifique d'un anticorps |
| AR128330A1 (es) | 2022-01-26 | 2024-04-17 | Genentech Inc | Inductores químicos de degradación conjugados con anticuerpo y métodos de estos |
| AR128331A1 (es) | 2022-01-26 | 2024-04-17 | Genentech Inc | Inductores químicos de degradación conjugados con anticuerpos y métodos de estos |
| EP4637833A2 (fr) | 2022-12-23 | 2025-10-29 | Genentech, Inc. | Conjugués d'agent de dégradation de céréblon et leurs utilisations |
| WO2024220546A2 (fr) | 2023-04-17 | 2024-10-24 | Peak Bio, Inc. | Anticorps et conjugués anticorps-médicament et procédés d'utilisation, processus synthétiques et intermédiaires |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999062941A2 (fr) * | 1998-06-01 | 1999-12-09 | Urogenesys, Inc. | Nouveaux antigenes transmembranaires du type serpentin exprimes dans des cancers humains et utilisation de ces antigenes |
| WO2000073509A2 (fr) * | 1999-06-01 | 2000-12-07 | Incyte Genomics, Inc. | Molecules utilisees a des fins diagnostiques et therapeutiques |
| WO2001005970A2 (fr) * | 1999-07-19 | 2001-01-25 | Incyte Genomics, Inc. | Proteines associees de liaison gtp |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5599686A (en) * | 1994-06-28 | 1997-02-04 | Merck & Co., Inc. | Peptides |
| US5820880A (en) * | 1995-06-07 | 1998-10-13 | The United States Of America As Represented By The Secretary Of The Army | Liposomal formulation |
| US6048970A (en) * | 1998-05-22 | 2000-04-11 | Incyte Pharmaceuticals, Inc. | Prostate growth-associated membrane proteins |
-
2001
- 2001-03-23 JP JP2001571877A patent/JP2004521602A/ja not_active Withdrawn
- 2001-03-23 WO PCT/US2001/009410 patent/WO2001072962A2/fr not_active Ceased
- 2001-03-23 CA CA002403637A patent/CA2403637A1/fr not_active Abandoned
- 2001-03-23 AU AU2001249411A patent/AU2001249411B2/en not_active Ceased
- 2001-03-23 EP EP01922630A patent/EP1268526A4/fr not_active Withdrawn
- 2001-03-23 AU AU4941101A patent/AU4941101A/xx active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999062941A2 (fr) * | 1998-06-01 | 1999-12-09 | Urogenesys, Inc. | Nouveaux antigenes transmembranaires du type serpentin exprimes dans des cancers humains et utilisation de ces antigenes |
| WO2000073509A2 (fr) * | 1999-06-01 | 2000-12-07 | Incyte Genomics, Inc. | Molecules utilisees a des fins diagnostiques et therapeutiques |
| WO2001005970A2 (fr) * | 1999-07-19 | 2001-01-25 | Incyte Genomics, Inc. | Proteines associees de liaison gtp |
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| Title |
|---|
| DATABASE EMBL [online] EBI; 10 December 1999 (1999-12-10), EMMANUEL DIAS NETO ET AL: "SHOTGUN SEQUENCING OF THE HUMAN TRANSCRIPTOME WITH ORF EXPRESSED SEQUENCE TAGS", XP002279053, Database accession no. AI908168 * |
| DATABASE EMBL [online] EBI; 22 February 2000 (2000-02-22), ISOGAI T., OTSUKI T., XP002241852, Database accession no. AK001691 * |
| DATABASE EMBL [online] EBI; 26 April 1999 (1999-04-26), MAHAIRAS G.G ET AL.: "Sequence-tagged connectors...", Database accession no. AQ456610 * |
| DIATCHENKO L ET AL: "SUPPRESSION SUBTRACTIVE HYBRIDIZATION: A METHOD FOR GENERATING DIFFERENTIALLY REGULATED OR TISSUE-SPECIFIC CDNA PROBES AND LIBRARIES", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 93, 1 June 1996 (1996-06-01), pages 6025 - 6030, XP002911922, ISSN: 0027-8424 * |
| MAHAIRAS G G ET AL: "SEQUENCE-TAGGED CONNECTORS: A SEQUENCE APPROACH TO MAPPING AND SCANNING THE HUMAN GENOME", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 96, no. 17, AQ456610, August 1999 (1999-08-01), pages 9739 - 9744, XP002175436, ISSN: 0027-8424 * |
| WATANABE G ET AL: "PROTEIN KINASE N (PKN) AND PKN-RELATED PROTEIN RHOPHILIN AS TARGETS OF SMALL GTPASE RHO", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 271, no. 5249, 2 February 1996 (1996-02-02), pages 645 - 648, XP001109460, ISSN: 0036-8075 * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU4941101A (en) | 2001-10-08 |
| CA2403637A1 (fr) | 2001-10-04 |
| AU2001249411B2 (en) | 2007-02-15 |
| WO2001072962A2 (fr) | 2001-10-04 |
| JP2004521602A (ja) | 2004-07-22 |
| EP1268526A2 (fr) | 2003-01-02 |
| AU2001249411B9 (en) | 2001-10-08 |
| WO2001072962A3 (fr) | 2002-01-17 |
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