EP1185549A4 - Dna encoding a human subunit of the 5-ht3 serotonin receptor - Google Patents

Dna encoding a human subunit of the 5-ht3 serotonin receptor

Info

Publication number: EP1185549A4
Authority: EP; European Patent Office
Prior art keywords: dna encoding; serotonin receptor; human subunit; subunit; human
Prior art date: 1999-05-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP00932357A

Other languages

German (de)

French (fr)

Other versions

EP1185549A2 (en

Inventor

Adrienne Dubin

Andrea Michael R D

Jayashree Pyatti

Jessica Y Zhu

Mark G Erlander

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Janssen Pharmaceuticals Inc

Original Assignee

Ortho McNeil Pharmaceutical Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-05-24

Filing date

2000-05-11

Publication date

2004-04-28

2000-05-11 Application filed by Ortho McNeil Pharmaceutical Inc filed Critical Ortho McNeil Pharmaceutical Inc

2002-03-13 Publication of EP1185549A2 publication Critical patent/EP1185549A2/en

2004-04-28 Publication of EP1185549A4 publication Critical patent/EP1185549A4/en

Status Withdrawn legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Psychiatry (AREA)
Hematology (AREA)
Endocrinology (AREA)
Obesity (AREA)
Immunology (AREA)
Gynecology & Obstetrics (AREA)
Zoology (AREA)
Hospice & Palliative Care (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Psychology (AREA)
Child & Adolescent Psychology (AREA)
Emergency Medicine (AREA)
Reproductive Health (AREA)
Cell Biology (AREA)
Toxicology (AREA)
Heart & Thoracic Surgery (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)

EP00932357A 1999-05-24 2000-05-11 Dna encoding a human subunit of the 5-ht3 serotonin receptor Withdrawn EP1185549A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US31771399A	1999-05-24	1999-05-24
PCT/US2000/013071 WO2000071741A2 (en)	1999-05-24	2000-05-11	Dna encoding a human subunit of the 5-ht3 serotonin receptor
US317713		2002-12-11

Publications (2)

Publication Number	Publication Date
EP1185549A2 EP1185549A2 (en)	2002-03-13
EP1185549A4 true EP1185549A4 (en)	2004-04-28

Family

ID=23234946

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP00932357A Withdrawn EP1185549A4 (en)	1999-05-24	2000-05-11	Dna encoding a human subunit of the 5-ht3 serotonin receptor

Country Status (6)

Country	Link
EP (1)	EP1185549A4 (en)
JP (1)	JP2004511202A (en)
AR (1)	AR024073A1 (en)
AU (1)	AU5009100A (en)
CA (1)	CA2374432A1 (en)
WO (1)	WO2000071741A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6365370B1 (en) *	1999-09-01	2002-04-02	Ortho-Mcneil Pharmaceutical, Inc.	DNA encoding a human subunit 5-HT3-C of the 5-HT3 serotonin receptor
WO2006021348A1 (en) *	2004-08-26	2006-03-02	Bayer Healthcare Ag	Diagnostics and therapeutics for diseases associated with 5-hydroxytryptamine receptor 3b (5-ht3b)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5472866A (en) *	1992-12-24	1995-12-05	Synaptic Pharmaceutical Corporation	DNA encoding 5-HT4A serotonin receptors

2000
- 2000-05-11 JP JP2000620118A patent/JP2004511202A/en active Pending
- 2000-05-11 EP EP00932357A patent/EP1185549A4/en not_active Withdrawn
- 2000-05-11 WO PCT/US2000/013071 patent/WO2000071741A2/en not_active Ceased
- 2000-05-11 CA CA002374432A patent/CA2374432A1/en not_active Abandoned
- 2000-05-11 AU AU50091/00A patent/AU5009100A/en not_active Abandoned
- 2000-05-23 AR ARP000102512A patent/AR024073A1/en unknown

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] XP002266828, retrieved from EBI Database accession no. AF080582 *
DATABASE EMBL [online] XP002266829, retrieved from EBI Database accession no. O95264 *
DATABASE EMBL [online] XP002266830, retrieved from EBI Database accession no. AF169255 *
DUBIN ADRIENNE E ET AL: "The pharmacological and functional characteristics of the serotonin 5-HT3A receptor are specifically modified by a 5-HT3B receptor subunit", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, vol. 274, no. 43, AF169255, 22 October 1999 (1999-10-22), pages 30799 - 30810, XP002236132, ISSN: 0021-9258, Retrieved from the Internet <URL:EBI> *
FLETCHER S ET AL: "Desperately seeking subunits: are native 5-HT3 receptors really homomeric complexes?", TRENDS IN PHARMACOLOGICAL SCIENCES, ELSEVIER TRENDS JOURNAL, CAMBRIDGE, GB, vol. 19, no. 6, 1 June 1998 (1998-06-01), pages 212 - 215, XP004145665, ISSN: 0165-6147 *
See also references of WO0071741A3 *

Also Published As

Publication number	Publication date
AR024073A1 (en)	2002-09-04
CA2374432A1 (en)	2000-11-30
AU5009100A (en)	2000-12-12
WO2000071741A2 (en)	2000-11-30
WO2000071741A3 (en)	2001-06-28
JP2004511202A (en)	2004-04-15
EP1185549A2 (en)	2002-03-13
WO2000071741A9 (en)	2001-07-26

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SI1221952T1 (en)	2005-10-31	Use of central cannabinoid receptor antagonist for preparing medicines
EP1237548A4 (en)	2003-07-23	Il-8 receptor antagonists

Legal Events

Date	Code	Title	Description
2002-01-25	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2002-03-13	17P	Request for examination filed	Effective date: 20011219
2002-03-13	AK	Designated contracting states	Kind code of ref document: A2 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
2002-03-13	AX	Request for extension of the european patent	Free format text: AL;LT;LV;MK;RO;SI
2002-05-29	RIN1	Information on inventor provided before grant (corrected)	Inventor name: ERLANDER, MARK, G. Inventor name: ZHU, JESSICA, Y. Inventor name: PYATTI, JAYASHREE Inventor name: D'ANDREA, MICHAEL, R. Inventor name: DUBIN, ADRIENNE
2004-03-10	RIC1	Information provided on ipc code assigned before grant	Ipc: 7C 07K 14/705 A
2004-04-28	A4	Supplementary search report drawn up and despatched	Effective date: 20040315
2004-11-26	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2005-01-12	18D	Application deemed to be withdrawn	Effective date: 20040703