EP1162205A3 - Procédé de préparation en grande quantité d'acide ascorbique 2-O-alpha-D-glucopyranosyle - Google Patents
Procédé de préparation en grande quantité d'acide ascorbique 2-O-alpha-D-glucopyranosyle Download PDFInfo
- Publication number
- EP1162205A3 EP1162205A3 EP01305024A EP01305024A EP1162205A3 EP 1162205 A3 EP1162205 A3 EP 1162205A3 EP 01305024 A EP01305024 A EP 01305024A EP 01305024 A EP01305024 A EP 01305024A EP 1162205 A3 EP1162205 A3 EP 1162205A3
- Authority
- EP
- European Patent Office
- Prior art keywords
- ascorbic acid
- glucopyranosyl
- producing
- alpha
- high content
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 title abstract 2
- MLSJBGYKDYSOAE-DCWMUDTNSA-N L-Ascorbic acid-2-glucoside Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O[C@@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)=C1O MLSJBGYKDYSOAE-DCWMUDTNSA-N 0.000 title 1
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 6
- 239000002211 L-ascorbic acid Substances 0.000 abstract 4
- 229960005070 ascorbic acid Drugs 0.000 abstract 4
- 235000000069 L-ascorbic acid Nutrition 0.000 abstract 3
- 150000001720 carbohydrates Chemical class 0.000 abstract 3
- 150000001450 anions Chemical class 0.000 abstract 2
- 239000000243 solution Substances 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 239000003957 anion exchange resin Substances 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000003480 eluent Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000172643 | 2000-06-08 | ||
| JP2000172643 | 2000-06-08 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| EP1162205A2 EP1162205A2 (fr) | 2001-12-12 |
| EP1162205A3 true EP1162205A3 (fr) | 2002-02-06 |
| EP1162205B1 EP1162205B1 (fr) | 2003-08-27 |
Family
ID=18675009
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP01305024A Expired - Lifetime EP1162205B1 (fr) | 2000-06-08 | 2001-06-08 | Procédé de préparation en grande quantité d'acide ascorbique 2-O-alpha-D-glucopyranosyle |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US6576446B2 (fr) |
| EP (1) | EP1162205B1 (fr) |
| KR (1) | KR100776895B1 (fr) |
| DE (1) | DE60100642T2 (fr) |
| TW (1) | TWI295294B (fr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8343951B2 (en) * | 2006-02-22 | 2013-01-01 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Volatile sulfide production inhibitor and method for inhibiting the production of volatile sulfide using the inhibitor |
| MX2012002696A (es) * | 2009-09-03 | 2012-08-15 | Hayashibara Biochem Lab | Composicion particulada que contiene ácido 2-0-alfa-d-glucosil-l-a scórbico anhidro cristalino, procedimiento para la producción de la misma, y sus usos. |
| US20110172180A1 (en) | 2010-01-13 | 2011-07-14 | Allergan Industrie. Sas | Heat stable hyaluronic acid compositions for dermatological use |
| US9114188B2 (en) | 2010-01-13 | 2015-08-25 | Allergan, Industrie, S.A.S. | Stable hydrogel compositions including additives |
| JP5056918B2 (ja) * | 2010-07-20 | 2012-10-24 | 富士ゼロックス株式会社 | 用紙処理装置および画像形成装置 |
| AU2012262047A1 (en) | 2011-06-03 | 2014-01-16 | Allergan, Inc. | Dermal filler compositions including antioxidants |
| WO2014103475A1 (fr) | 2012-12-27 | 2014-07-03 | 株式会社林原 | Composition antivieillissement pour l'extérieur de la peau et son procédé de production |
| CN103755756B (zh) * | 2014-02-11 | 2015-07-08 | 江苏诚信药业有限公司 | 一种制备维生素c葡萄糖苷的工艺系统及其工艺方法 |
| CN103923136B (zh) * | 2014-04-20 | 2019-01-18 | 厦门世达膜科技有限公司 | 一种抗坏血酸葡糖苷的生产方法 |
| CN105461768B (zh) * | 2014-08-25 | 2018-10-30 | 上海医药工业研究院 | 一种2-O-α-D-葡萄糖基-L-抗坏血酸的制备方法 |
| CN109476693A (zh) * | 2016-07-29 | 2019-03-15 | 佳里多控股公司 | 2-O-α-D-糖基-L-抗坏血酸金属盐、其作为抗氧化剂的用途及其粉末的制造方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06228183A (ja) * | 1993-02-03 | 1994-08-16 | Unitika Ltd | L−アスコルビン酸糖誘導体の精製方法 |
| US5508391A (en) * | 1989-10-21 | 1996-04-16 | Kabushiki Kaisha Hayashibara | Crystalline 2-O-α-D-glucopyranosyl-L-ascorbic acid, and its preparation and uses |
-
2001
- 2001-06-08 TW TW090113958A patent/TWI295294B/zh not_active IP Right Cessation
- 2001-06-08 DE DE60100642T patent/DE60100642T2/de not_active Expired - Lifetime
- 2001-06-08 US US09/875,963 patent/US6576446B2/en not_active Expired - Lifetime
- 2001-06-08 KR KR1020010032124A patent/KR100776895B1/ko not_active Expired - Lifetime
- 2001-06-08 EP EP01305024A patent/EP1162205B1/fr not_active Expired - Lifetime
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5508391A (en) * | 1989-10-21 | 1996-04-16 | Kabushiki Kaisha Hayashibara | Crystalline 2-O-α-D-glucopyranosyl-L-ascorbic acid, and its preparation and uses |
| JPH06228183A (ja) * | 1993-02-03 | 1994-08-16 | Unitika Ltd | L−アスコルビン酸糖誘導体の精製方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1162205A2 (fr) | 2001-12-12 |
| KR100776895B1 (ko) | 2007-11-19 |
| US6576446B2 (en) | 2003-06-10 |
| TWI295294B (en) | 2008-04-01 |
| DE60100642T2 (de) | 2004-06-17 |
| US20010051711A1 (en) | 2001-12-13 |
| EP1162205B1 (fr) | 2003-08-27 |
| DE60100642D1 (de) | 2003-10-02 |
| KR20010111053A (ko) | 2001-12-15 |
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