EP1158972A4 - Traitement de l'hypertension avec des composes inhibant la destruction des enkephalines ou des endorphines - Google Patents

Traitement de l'hypertension avec des composes inhibant la destruction des enkephalines ou des endorphines

Info

Publication number: EP1158972A4
Authority: EP; European Patent Office
Prior art keywords: enkephalins; endorphins; hypertension; destruction; inhibit
Prior art date: 1999-01-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP00903252A

Other languages

German (de)

English (en)

Other versions

EP1158972A1 (fr

Inventor

Seymour Ehrenpreis

Kenneth Blum

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Individual

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-01-12

Filing date

2000-01-12

Publication date

2003-05-02

2000-01-12 Application filed by Individual filed Critical Individual

2001-12-05 Publication of EP1158972A1 publication Critical patent/EP1158972A1/fr

2003-05-02 Publication of EP1158972A4 publication Critical patent/EP1158972A4/fr

Status Withdrawn legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Inorganic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

EP00903252A 1999-01-12 2000-01-12 Traitement de l'hypertension avec des composes inhibant la destruction des enkephalines ou des endorphines Withdrawn EP1158972A4 (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US11572499P	1999-01-12	1999-01-12
US115724P		1999-01-12
PCT/US2000/000722 WO2000041686A1 (fr)	1999-01-12	2000-01-12	Traitement de l'hypertension avec des composes inhibant la destruction des enkephalines ou des endorphines

Publications (2)

Publication Number	Publication Date
EP1158972A1 EP1158972A1 (fr)	2001-12-05
EP1158972A4 true EP1158972A4 (fr)	2003-05-02

Family

ID=22363061

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP00903252A Withdrawn EP1158972A4 (fr)	1999-01-12	2000-01-12	Traitement de l'hypertension avec des composes inhibant la destruction des enkephalines ou des endorphines

Country Status (4)

Country	Link
EP (1)	EP1158972A4 (fr)
AU (1)	AU2502700A (fr)
CA (1)	CA2363847A1 (fr)
WO (1)	WO2000041686A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE476188T1 (de) *	2002-05-14	2010-08-15	Nipro Corp	Medikament zur prävention und behandlung von familiärer amyloid polyneuropathie
US9937146B2 (en) *	2016-03-23	2018-04-10	Bioadatp, Llc	Enkephalin-influencing composition and method

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DD229931A1 (de) *	1984-11-09	1985-11-20	Adw Ddr	Verfahren zur herstellung eines mittels mit antistresswirkung
US4749688A (en) *	1986-06-20	1988-06-07	Schering Corporation	Use of neutral metalloendopeptidase inhibitors in the treatment of hypertension
GB2286528A (en) *	1994-02-17	1995-08-23	Robert John Woodward	Dietary supplement

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5238932A (en) *	1992-05-20	1993-08-24	Merrell Dow Pharmaceuticals Inc.	Mercaptoacetylamide tricyclic derivatives useful as inhibitors of enkephalinase
US5420271A (en) *	1992-08-24	1995-05-30	Merrell Dow Pharmaceuticals, Inc.	2-substituted indane-2-mercaptoacetylamide tricyclic derivatives useful as inhibitors of enkephalinase
US5425954A (en) *	1993-09-30	1995-06-20	Curafas Incorporated	Topical amino acid - vitamin complex compositions for pharmaceutical and cosmetic use

2000
- 2000-01-12 CA CA002363847A patent/CA2363847A1/fr not_active Abandoned
- 2000-01-12 AU AU25027/00A patent/AU2502700A/en not_active Abandoned
- 2000-01-12 WO PCT/US2000/000722 patent/WO2000041686A1/fr not_active Ceased
- 2000-01-12 EP EP00903252A patent/EP1158972A4/fr not_active Withdrawn

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DD229931A1 (de) *	1984-11-09	1985-11-20	Adw Ddr	Verfahren zur herstellung eines mittels mit antistresswirkung
US4749688A (en) *	1986-06-20	1988-06-07	Schering Corporation	Use of neutral metalloendopeptidase inhibitors in the treatment of hypertension
GB2286528A (en) *	1994-02-17	1995-08-23	Robert John Woodward	Dietary supplement

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO0041686A1 *

Also Published As

Publication number	Publication date
EP1158972A1 (fr)	2001-12-05
AU2502700A (en)	2000-08-01
WO2000041686A1 (fr)	2000-07-20
CA2363847A1 (fr)	2000-07-20

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FR2765773B1 (fr)	1999-08-27	Machine agricole de type desileuse ou desileuse-pailleuse
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FR2714922B1 (fr)	1996-02-23	Agencement d'éléments préfabriqués applicable au domaine de la décoration.

Legal Events

Date	Code	Title	Description
2001-10-19	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2001-12-05	17P	Request for examination filed	Effective date: 20010813
2001-12-05	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
2001-12-05	AX	Request for extension of the european patent	Free format text: AL;LT;LV;MK;RO;SI
2003-01-08	RIC1	Information provided on ipc code assigned before grant	Free format text: 7A 61K 45/00 A, 7A 61K 31/198 B, 7A 61K 31/401 B, 7A 61K 31/52 B, 7A 61P 9/12 B
2003-05-02	A4	Supplementary search report drawn up and despatched	Effective date: 20030317
2003-08-13	17Q	First examination report despatched	Effective date: 20030701
2004-05-28	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2004-07-14	18D	Application deemed to be withdrawn	Effective date: 20040113