EP1154801A4 - Integration de cellules progenitrices neurales transplantees dans les tissus nerveux de destinataires dystrophiques matures et immatures - Google Patents

Integration de cellules progenitrices neurales transplantees dans les tissus nerveux de destinataires dystrophiques matures et immatures

Info

Publication number: EP1154801A4
Authority: EP; European Patent Office
Prior art keywords: neural; preceller; dystroce; receivers; tire
Prior art date: 1999-02-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP00907260A

Other languages

German (de)

English (en)

Other versions

EP1154801A1 (fr

Inventor

Michael J Young

Fred H Gage

Jasodhara Ray

Simon J Whiteley

Henry Klassen

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Schepens Eye Research Institute Inc

Salk Institute for Biological Studies

Original Assignee

Schepens Eye Research Institute Inc

Salk Institute for Biological Studies

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-02-11

Filing date

2000-02-11

Publication date

2002-08-21

2000-02-11 Application filed by Schepens Eye Research Institute Inc, Salk Institute for Biological Studies filed Critical Schepens Eye Research Institute Inc

2001-11-21 Publication of EP1154801A1 publication Critical patent/EP1154801A1/fr

2002-08-21 Publication of EP1154801A4 publication Critical patent/EP1154801A4/fr

Status Withdrawn legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Biomedical Technology (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Addiction (AREA)
Psychiatry (AREA)
Ophthalmology & Optometry (AREA)
Diabetes (AREA)
Pain & Pain Management (AREA)
Psychology (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Cardiology (AREA)
Cell Biology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Developmental Biology & Embryology (AREA)
Obesity (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Microbiology (AREA)

EP00907260A 1999-02-11 2000-02-11 Integration de cellules progenitrices neurales transplantees dans les tissus nerveux de destinataires dystrophiques matures et immatures Withdrawn EP1154801A4 (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US11964299P	1999-02-11	1999-02-11
US119642P		1999-02-11
PCT/US2000/003534 WO2000047238A1 (fr)	1999-02-11	2000-02-11	Integration de cellules progenitrices neurales transplantees dans les tissus nerveux de destinataires dystrophiques matures et immatures

Publications (2)

Publication Number	Publication Date
EP1154801A1 EP1154801A1 (fr)	2001-11-21
EP1154801A4 true EP1154801A4 (fr)	2002-08-21

Family

ID=22385498

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP00907260A Withdrawn EP1154801A4 (fr)	1999-02-11	2000-02-11	Integration de cellules progenitrices neurales transplantees dans les tissus nerveux de destinataires dystrophiques matures et immatures

Country Status (5)

Country	Link
EP (1)	EP1154801A4 (fr)
JP (1)	JP2002536423A (fr)
AU (1)	AU2878400A (fr)
CA (1)	CA2362476A1 (fr)
WO (1)	WO2000047238A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2002230669A1 (en) *	2000-11-06	2002-05-15	The Salk Institute For Biological Studies	Postmortem stem cells
US7312025B2 (en)	2002-07-12	2007-12-25	University Of Washington	Methods and systems for extended in vitro culture of neuronal cells
AU2003302707B2 (en) *	2002-12-02	2008-10-02	Anges Mg, Inc.	Method for culturing neural stem cells using hepatocyte growth factor
US9061017B2 (en)	2006-05-03	2015-06-23	The Schepens Eye Research Institute, Inc.	Isolation and therapeutic application of adult retinal stem cells collected from extra-retinal tissues
WO2007130060A2 (fr)	2006-05-03	2007-11-15	Schepens Eye Research	Isolation et application thérapeutique de cellules souches rétiniennes adultes prélevées sur des tissus extra-rétiniens
JO3626B1 (ar) *	2012-02-23	2020-08-27	Merial Inc	تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها

2000
- 2000-02-11 EP EP00907260A patent/EP1154801A4/fr not_active Withdrawn
- 2000-02-11 CA CA002362476A patent/CA2362476A1/fr not_active Abandoned
- 2000-02-11 JP JP2000598189A patent/JP2002536423A/ja active Pending
- 2000-02-11 AU AU28784/00A patent/AU2878400A/en not_active Abandoned
- 2000-02-11 WO PCT/US2000/003534 patent/WO2000047238A1/fr not_active Ceased

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
GAGE F H ET AL: "SURVIVAL AND DIFFERENTIATION OF ADULT NEURONAL PROGENITOR CELLS TRANSPLANTED TO THE ADULT BRAIN", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 92, 1 December 1995 (1995-12-01), pages 11879 - 11883, XP002034681, ISSN: 0027-8424 *
See also references of WO0047238A1 *
SUHONEN JAANA O ET AL: "Differentiation of adult hippocampus-derived progenitors into olfactory neurons in vivo.", NATURE (LONDON), vol. 383, no. 6601, 1996, pages 624 - 627, XP002203051, ISSN: 0028-0836 *
TAKAHASHI M ET AL: "WIDESPREAD INTEGRATION AND SURVIVAL OF ADULT-DERIVED NEURAL PROGENITOR CELLS IN THE DEVELOPING OPTIC RETINA", MOLECULAR AND CELLULAR NEUROSCIENCES, SAN DIEGO, US, vol. 12, December 1998 (1998-12-01), pages 340 - 348, XP002926797, ISSN: 1044-7431 *

Also Published As

Publication number	Publication date
AU2878400A (en)	2000-08-29
WO2000047238A1 (fr)	2000-08-17
JP2002536423A (ja)	2002-10-29
CA2362476A1 (fr)	2000-08-17
WO2000047238A9 (fr)	2001-07-26
EP1154801A1 (fr)	2001-11-21

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Legal Events

Date	Code	Title	Description
2001-10-05	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2001-11-21	17P	Request for examination filed	Effective date: 20010911
2001-11-21	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
2001-11-21	AX	Request for extension of the european patent	Free format text: AL;LT;LV;MK;RO;SI
2002-08-21	A4	Supplementary search report drawn up and despatched	Effective date: 20020708
2002-08-21	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
2004-01-19	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2004-03-03	18D	Application deemed to be withdrawn	Effective date: 20030902