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EP1146904A4 - Use of hydroxyurea and a reverse transcriptase inhibitor to induce autovaccination by autologous hiv - Google Patents

Use of hydroxyurea and a reverse transcriptase inhibitor to induce autovaccination by autologous hiv

Info

Publication number
EP1146904A4
EP1146904A4 EP00905949A EP00905949A EP1146904A4 EP 1146904 A4 EP1146904 A4 EP 1146904A4 EP 00905949 A EP00905949 A EP 00905949A EP 00905949 A EP00905949 A EP 00905949A EP 1146904 A4 EP1146904 A4 EP 1146904A4
Authority
EP
European Patent Office
Prior art keywords
autovaccination
hydroxyurea
induce
reverse transcriptase
transcriptase inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00905949A
Other languages
German (de)
French (fr)
Other versions
EP1146904A1 (en
Inventor
Franco Lori
Juliana Lisziewicz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/493,769 external-priority patent/US20030095988A1/en
Application filed by Individual filed Critical Individual
Publication of EP1146904A1 publication Critical patent/EP1146904A1/en
Publication of EP1146904A4 publication Critical patent/EP1146904A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/21—Retroviridae, e.g. equine infectious anemia virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP00905949A 1999-02-03 2000-02-02 Use of hydroxyurea and a reverse transcriptase inhibitor to induce autovaccination by autologous hiv Withdrawn EP1146904A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US24375399A 1999-02-03 1999-02-03
US243753 1999-02-03
US09/493,769 US20030095988A1 (en) 2000-01-28 2000-01-28 Method of inducing autovaccination against HIV infection using structured treatment interruptions
US493769 2000-01-28
PCT/US2000/002754 WO2000045844A1 (en) 1999-02-03 2000-02-02 Use of hydroxyurea and a reverse transcriptase inhibitor to induce autovaccination by autologous hiv

Publications (2)

Publication Number Publication Date
EP1146904A1 EP1146904A1 (en) 2001-10-24
EP1146904A4 true EP1146904A4 (en) 2004-09-15

Family

ID=26936052

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00905949A Withdrawn EP1146904A4 (en) 1999-02-03 2000-02-02 Use of hydroxyurea and a reverse transcriptase inhibitor to induce autovaccination by autologous hiv

Country Status (3)

Country Link
EP (1) EP1146904A4 (en)
AU (1) AU2753700A (en)
WO (1) WO2000045844A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030095988A1 (en) * 2000-01-28 2003-05-22 Julianna Lisziewicz Method of inducing autovaccination against HIV infection using structured treatment interruptions
FR2821556B1 (en) * 2001-03-02 2003-04-25 Aventis Pasteur USE OF LIPOPEPTIDES FOR IMMUNOTHERAPY OF HIV + SUBJECTS
US20030044428A1 (en) * 2001-01-26 2003-03-06 Moss Ronald B. Method for treating an HIV-infected individual by combining immunization with structured interruption of anti-retroviral treatment

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994027590A1 (en) * 1993-05-21 1994-12-08 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services New procedure to block the replication of reverse transcriptase dependent viruses by the use of inhibitors of deoxynucleotides synthesis
WO1996022777A1 (en) * 1995-01-25 1996-08-01 Compagnie De Developpement Aguettant Mixtures of dideoxy-nucleosides and hydroxycarbamide for inhibiting retroviral spread

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5413999A (en) * 1991-11-08 1995-05-09 Merck & Co., Inc. HIV protease inhibitors useful for the treatment of AIDS
US5521161A (en) * 1993-12-20 1996-05-28 Compagnie De Developpment Aguettant S.A. Method of treating HIV in humans by administration of ddI and hydroxycarbamide
US6114312A (en) * 1997-03-07 2000-09-05 Research Institute For Genetic And Human Therapy (R.I.G.H.T.) Method of inhibiting human immunodeficiency virus by combined use of hydroxyurea, a nucleoside analog, and a protease inhibitor

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994027590A1 (en) * 1993-05-21 1994-12-08 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services New procedure to block the replication of reverse transcriptase dependent viruses by the use of inhibitors of deoxynucleotides synthesis
WO1996022777A1 (en) * 1995-01-25 1996-08-01 Compagnie De Developpement Aguettant Mixtures of dideoxy-nucleosides and hydroxycarbamide for inhibiting retroviral spread

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO0045844A1 *

Also Published As

Publication number Publication date
EP1146904A1 (en) 2001-10-24
WO2000045844A1 (en) 2000-08-10
AU2753700A (en) 2000-08-25

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 20010809

AK Designated contracting states

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Effective date: 20040729

STAA Information on the status of an ep patent application or granted ep patent

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18D Application deemed to be withdrawn

Effective date: 20040901