[go: up one dir, main page]

EP1021168A4 - Dispositif d'administration de microparticules ou de nanoparticules de polymeres - Google Patents

Dispositif d'administration de microparticules ou de nanoparticules de polymeres

Info

Publication number
EP1021168A4
EP1021168A4 EP98952243A EP98952243A EP1021168A4 EP 1021168 A4 EP1021168 A4 EP 1021168A4 EP 98952243 A EP98952243 A EP 98952243A EP 98952243 A EP98952243 A EP 98952243A EP 1021168 A4 EP1021168 A4 EP 1021168A4
Authority
EP
European Patent Office
Prior art keywords
particulate
nano
micro
delivery system
polymeric delivery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98952243A
Other languages
German (de)
English (en)
Other versions
EP1021168A1 (fr
Inventor
Ales Prokop
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vanderbilt University
Original Assignee
Vanderbilt University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vanderbilt University filed Critical Vanderbilt University
Publication of EP1021168A1 publication Critical patent/EP1021168A1/fr
Publication of EP1021168A4 publication Critical patent/EP1021168A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5115—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5169—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
EP98952243A 1997-10-09 1998-10-09 Dispositif d'administration de microparticules ou de nanoparticules de polymeres Withdrawn EP1021168A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6294397P 1997-10-09 1997-10-09
US62943P 1997-10-09
PCT/US1998/021455 WO1999018934A1 (fr) 1997-10-09 1998-10-09 Dispositif d'administration de microparticules ou de nanoparticules de polymeres

Publications (2)

Publication Number Publication Date
EP1021168A1 EP1021168A1 (fr) 2000-07-26
EP1021168A4 true EP1021168A4 (fr) 2006-08-30

Family

ID=22045878

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98952243A Withdrawn EP1021168A4 (fr) 1997-10-09 1998-10-09 Dispositif d'administration de microparticules ou de nanoparticules de polymeres

Country Status (3)

Country Link
EP (1) EP1021168A4 (fr)
AU (1) AU9799198A (fr)
WO (1) WO1999018934A1 (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19810965A1 (de) * 1998-03-13 1999-09-16 Aventis Res & Tech Gmbh & Co Nanopartikel, Verfahren zu ihrer Herstellung und ihre Verwendung
AU1186401A (en) * 1999-06-23 2001-01-22 Sedum Laboratories, Inc. Ionically formulated biomolecule microcarriers
AU2463701A (en) 1999-12-29 2001-07-09 Nanodelivery, Inc. Drug delivery system exhibiting permeability control
DE60222160T2 (de) * 2001-10-12 2008-06-12 Elan Pharma International Ltd., Athlone Zusammensetzungen mit einer kombination aus eigenschaften sofortiger freisetzung und kontrollierter freisetzung
US20040014698A1 (en) * 2002-07-18 2004-01-22 Gonzalo Hortelano Oral administration of therapeutic agent coupled to transporting agent
ES2226567B1 (es) * 2003-06-20 2006-07-01 Universidad De Santiago De Compostela Nanoparticulas de acido hialuronico.
ES2246694B1 (es) 2004-04-29 2007-05-01 Instituto Cientifico Y Tecnologico De Navarra, S.A. Nanoparticulas pegiladas.
ES2246695B1 (es) 2004-04-29 2007-05-01 Instituto Cientifico Y Tecnologico De Navarra, S.A. Composicion estimuladora de la respuesta inmunitaria que comprende nanoparticulas a base de un copolimero de metil vinil eter y anhidrido maleico.
KR100604976B1 (ko) * 2004-09-03 2006-07-28 학교법인연세대학교 다작용기 리간드로 안정화된 수용성 나노입자
US7282194B2 (en) * 2004-10-05 2007-10-16 Gp Medical, Inc. Nanoparticles for protein drug delivery
WO2006091180A2 (fr) * 2005-02-25 2006-08-31 Ali Demir Sezer Systemes vecteurs du medicament multiparticulaire fucoidane
EP1871397A1 (fr) * 2005-03-17 2008-01-02 Cargill, Incorporated Compositions liquides avec glycosylaminoglycane pour applications liees a la sante
JP2009527472A (ja) 2006-02-17 2009-07-30 トパス ゲーエムベーハー 細胞特異性を有する三区画ポリマーナノ粒子を使用した多モード撮像法概要
WO2007141050A2 (fr) * 2006-06-08 2007-12-13 Bayer Schering Pharma Aktiengesellschaft Nanoparticules polymères solides fonctionnalisées pour applications diagnostiques et thérapeutiques
US20100166865A1 (en) * 2006-08-17 2010-07-01 Novartis Ag Nanoparticle compositions
DE102007059752A1 (de) * 2007-12-10 2009-06-18 Bayer Schering Pharma Aktiengesellschaft Funktionalisierte, feste Polymernanopartikel enthaltend Epothilone
EP2070521A1 (fr) * 2007-12-10 2009-06-17 Bayer Schering Pharma Aktiengesellschaft Nanoparticules à surface modifiée
JP2012506900A (ja) * 2008-10-28 2012-03-22 ウニベルシダーデ デ サンティアゴ デ コンポステラ アニオン性ポリマーから調製されるナノ粒子系
ES2342588B2 (es) * 2008-10-28 2011-03-10 Universidade De Santiago De Compostela Sistemas nanoparticulares elaborados a base de polimeros anionicos.
ES2341165B2 (es) * 2008-10-28 2010-10-27 Universidad De Santiago De Compostela Nanoparticulas de acido colominico y derivados.
ES2345806B1 (es) * 2009-03-30 2011-07-22 Universidad De Santiago De Compostela Sistemas nanoparticulares elaborados a base de polimeros anionicos para administrar moleculas bioactivas para uso cosmetico.
WO2010100781A1 (fr) * 2009-03-06 2010-09-10 国立大学法人東京大学 Composition pour l'administration d'acide nucléique
JP7140684B2 (ja) * 2016-06-01 2022-09-21 アクセス ツー アドバンスト ヘルス インスティチュート サイジング剤含有ナノアラム粒子
WO2017220611A1 (fr) * 2016-06-20 2017-12-28 Virbac Composition pharmaceutique par voie orale comprenant un agent pharmaceutiquement actif, au moins un polymère bioadhésif cationique et au moins deux polymères anioniques
CN113171355B (zh) * 2021-04-25 2022-07-19 华中农业大学 具有m细胞靶向的硫酸黏杆菌素自组装纳米颗粒、制备方法及应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0454044A2 (fr) * 1990-04-25 1991-10-30 Hoechst Aktiengesellschaft Produit pharmacologique contenant des composés de polyélectrolytes sous forme de microparticules et au moins un agent actif

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4933185A (en) * 1986-09-24 1990-06-12 Massachusetts Institute Of Technology System for controlled release of biologically active compounds
US5562909A (en) * 1993-07-12 1996-10-08 Massachusetts Institute Of Technology Phosphazene polyelectrolytes as immunoadjuvants

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0454044A2 (fr) * 1990-04-25 1991-10-30 Hoechst Aktiengesellschaft Produit pharmacologique contenant des composés de polyélectrolytes sous forme de microparticules et au moins un agent actif

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
See also references of WO9918934A1 *
TAYLOR WANG ET AL.: "An encapsulation system for the immunoisolation of pancreatic islets", NATURE BIOTECHNOLOGY., vol. 15, no. 4, 1997, USNATURE PUBLISHING GROUP, NEW YORK, NY., pages 358 - 362, XP008066998 *

Also Published As

Publication number Publication date
EP1021168A1 (fr) 2000-07-26
WO1999018934A1 (fr) 1999-04-22
AU9799198A (en) 1999-05-03

Similar Documents

Publication Publication Date Title
EP1021168A4 (fr) Dispositif d'administration de microparticules ou de nanoparticules de polymeres
SG80049A1 (en) Delivery system
GB2319184B (en) Drug delivery device
IL120943A0 (en) Transdermal delivery system
ZA979552B (en) Delivery device
GB2338414B (en) Intravesical drug delivery system
IL143087A0 (en) Drug delivery systems and methods
EP1015971A4 (fr) Systeme fiable de transmission d'evenements
IL125042A0 (en) Gastrointestinal drug delivery system
HUP0300246A3 (en) Delivery system
GB9605690D0 (en) Particle delivery
EP0907998A4 (fr) Systeme de plage d'alimentation/apport d'alimentation
ZA9811086B (en) Delivery devices and their use
EP0989878A4 (fr) Systeme d'administration de medicaments
EP1034290A4 (fr) Systeme d'expression et de diffusion propre au flavivirus
ZA975339B (en) Perfume delivery system
GB9721367D0 (en) Delivery system
EP1021137A4 (fr) Systeme d'administration de medicaments
HUP9900086A3 (en) Delivery device
GB2329491B (en) Collection and delivery system
GB9404293D0 (en) Drug delivery system
GB2308902B (en) Peripheral module and microprocessor system
GB9600471D0 (en) Drug delivery system
GB2309559B (en) Microprocessor and system
GB2337520B (en) Delivery system

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20000508

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

A4 Supplementary search report drawn up and despatched

Effective date: 20060801

17Q First examination report despatched

Effective date: 20070605

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20071016