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EP1007063A4 - Regeneration osseuse dans le cadre de l'osteoporose a l'aide de cellules mesenchymateuses de moelle osseuse humaine - Google Patents

Regeneration osseuse dans le cadre de l'osteoporose a l'aide de cellules mesenchymateuses de moelle osseuse humaine

Info

Publication number
EP1007063A4
EP1007063A4 EP98903613A EP98903613A EP1007063A4 EP 1007063 A4 EP1007063 A4 EP 1007063A4 EP 98903613 A EP98903613 A EP 98903613A EP 98903613 A EP98903613 A EP 98903613A EP 1007063 A4 EP1007063 A4 EP 1007063A4
Authority
EP
European Patent Office
Prior art keywords
bone
mesenchymatory
mare
osteoporosis
context
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP98903613A
Other languages
German (de)
English (en)
Other versions
EP1007063A1 (fr
Inventor
Scott P Bruder
Arnold I Caplan
James S Burns
Daniel Marshak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Case Western Reserve University
Osiris Therapeutics Inc
Original Assignee
Case Western Reserve University
Osiris Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Case Western Reserve University, Osiris Therapeutics Inc filed Critical Case Western Reserve University
Priority to EP10000798A priority Critical patent/EP2179738A3/fr
Publication of EP1007063A1 publication Critical patent/EP1007063A1/fr
Publication of EP1007063A4 publication Critical patent/EP1007063A4/fr
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Developmental Biology & Embryology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP98903613A 1997-01-24 1998-01-22 Regeneration osseuse dans le cadre de l'osteoporose a l'aide de cellules mesenchymateuses de moelle osseuse humaine Ceased EP1007063A4 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP10000798A EP2179738A3 (fr) 1997-01-24 1998-01-22 Utilisation de cellules souche mesenchymales pour le traitement de l'osteoporose

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3638897P 1997-01-24 1997-01-24
US36388P 1997-01-24
PCT/US1998/001112 WO1998032450A1 (fr) 1997-01-24 1998-01-22 Regeneration osseuse dans le cadre de l'osteoporose a l'aide de cellules mesenchymateuses de moelle osseuse humaine

Publications (2)

Publication Number Publication Date
EP1007063A1 EP1007063A1 (fr) 2000-06-14
EP1007063A4 true EP1007063A4 (fr) 2002-04-24

Family

ID=21888339

Family Applications (2)

Application Number Title Priority Date Filing Date
EP98903613A Ceased EP1007063A4 (fr) 1997-01-24 1998-01-22 Regeneration osseuse dans le cadre de l'osteoporose a l'aide de cellules mesenchymateuses de moelle osseuse humaine
EP10000798A Withdrawn EP2179738A3 (fr) 1997-01-24 1998-01-22 Utilisation de cellules souche mesenchymales pour le traitement de l'osteoporose

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP10000798A Withdrawn EP2179738A3 (fr) 1997-01-24 1998-01-22 Utilisation de cellules souche mesenchymales pour le traitement de l'osteoporose

Country Status (5)

Country Link
EP (2) EP1007063A4 (fr)
JP (1) JP2001509163A (fr)
AU (1) AU6033898A (fr)
CA (1) CA2278539A1 (fr)
WO (1) WO1998032450A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100679923B1 (ko) 2000-08-07 2007-02-07 신정욱 돼지의 해면골을 취하여 무기물화함으로써 골이식용 해면골의 기초 본블록을 제조하는 방법
JP2007508018A (ja) 2003-10-08 2007-04-05 べト−ステム インコーポレイテッド 新規の幹細胞組成物の調製法および使用法、ならびにこの組成物を含有するキット
US20130089529A1 (en) * 2010-06-11 2013-04-11 University-Industry Cooperation Group Of Kyunghee University Agent for osteogenesis using substance-p and preparation process thereof
EP3193953B1 (fr) 2014-09-19 2020-03-11 Osiris Therapeutics, Inc. Produit de réparation osseuse et ses procédés d'utilisation
RU2644650C2 (ru) 2014-12-01 2018-02-13 Общество с ограниченной ответственностью "Т-Хелпер Клеточные Технологии" Материал стволовых клеток и способ его получения
RU2708329C2 (ru) 2016-05-31 2019-12-05 Общество с ограниченной ответственностью "Т-Хелпер Клеточные Технологии" Материал стволовых клеток, композиции и способы применения
CN113876703A (zh) * 2021-11-06 2022-01-04 王啸远 一种骨髓间充质干细胞注射液及其制备方法和应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996030031A1 (fr) * 1995-03-28 1996-10-03 Thomas Jefferson University Cellules de stroma isolees et leur methode d'utilisation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5053050A (en) * 1988-04-29 1991-10-01 Samuel Itay Compositions for repair of cartilage and bone
US5486359A (en) * 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US5226914A (en) * 1990-11-16 1993-07-13 Caplan Arnold I Method for treating connective tissue disorders

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996030031A1 (fr) * 1995-03-28 1996-10-03 Thomas Jefferson University Cellules de stroma isolees et leur methode d'utilisation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9832450A1 *

Also Published As

Publication number Publication date
EP1007063A1 (fr) 2000-06-14
AU6033898A (en) 1998-08-18
WO1998032450A1 (fr) 1998-07-30
CA2278539A1 (fr) 1998-07-30
JP2001509163A (ja) 2001-07-10
EP2179738A2 (fr) 2010-04-28
EP2179738A3 (fr) 2010-05-05

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